Design and Synthesis of Selurampanel, a Novel Orally Active and Competitive AMPA Receptor Antagonist
Orain, David, Tasdelen, Engin, Haessig, Samuel, Koller, Manuel, Picard, Anne, Dubois, Celine, Lingenhoehl, Kurt, Desrayaud, Sandrine, Floersheim, Phillip, Carcache, David, Urwyler, Stephan, Kallen, Joerg, Mattes, Henri
Published in ChemMedChem (03.02.2017)
Published in ChemMedChem (03.02.2017)
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ABP688, a novel selective and high affinity ligand for the labeling of mGlu5 receptors: Identification, in vitro pharmacology, pharmacokinetic and biodistribution studies
Hintermann, Samuel, Vranesic, Ivo, Allgeier, Hans, Brülisauer, Armin, Hoyer, Daniel, Lemaire, Michel, Moenius, Thomas, Urwyler, Stephan, Whitebread, Steven, Gasparini, Fabrizio, Auberson, Yves P.
Published in Bioorganic & medicinal chemistry (15.01.2007)
Published in Bioorganic & medicinal chemistry (15.01.2007)
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Discovery of NMDA Glycine Site Inhibitors from the Chemical Universe Database GDB
Nguyen, Kong Thong, Syed, Salahuddin, Urwyler, Stephan, Bertrand, Sonia, Bertrand, Daniel, Reymond, Jean-Louis
Published in ChemMedChem (20.10.2008)
Published in ChemMedChem (20.10.2008)
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N,N'-Dicyclopentyl-2-methylsulfanyl-5-nitro-pyrimidine-4,6-diamine (GS39783) and structurally related compounds: novel allosteric enhancers of gamma-aminobutyric acidB receptor function
Urwyler, Stephan, Pozza, Mario F, Lingenhoehl, Kurt, Mosbacher, Johannes, Lampert, Christina, Froestl, Wolfgang, Koller, Manuel, Kaupmann, Klemens
Published in The Journal of pharmacology and experimental therapeutics (01.10.2003)
Published in The Journal of pharmacology and experimental therapeutics (01.10.2003)
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Drug Design, in Vitro Pharmacology, and Structure−Activity Relationships of 3-Acylamino-2-aminopropionic Acid Derivatives, a Novel Class of Partial Agonists at the Glycine Site on the N-Methyl-d-aspartate (NMDA) Receptor Complex
Urwyler, Stephan, Floersheim, Philipp, Roy, Bernard L, Koller, Manuel
Published in Journal of medicinal chemistry (27.08.2009)
Published in Journal of medicinal chemistry (27.08.2009)
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Cover Picture: Design and Synthesis of Selurampanel, a Novel Orally Active and Competitive AMPA Receptor Antagonist (ChemMedChem 3/2017)
Orain, David, Tasdelen, Engin, Haessig, Samuel, Koller, Manuel, Picard, Anne, Dubois, Celine, Lingenhoehl, Kurt, Desrayaud, Sandrine, Floersheim, Phillip, Carcache, David, Urwyler, Stephan, Kallen, Joerg, Mattes, Henri
Published in ChemMedChem (03.02.2017)
Published in ChemMedChem (03.02.2017)
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Quinazolinedione sulfonamides: A novel class of competitive AMPA receptor antagonists with oral activity
Koller, Manuel, Lingenhoehl, Kurt, Schmutz, Markus, Vranesic, Ivan-Toma, Kallen, Joerg, Auberson, Yves P., Carcache, David A., Mattes, Henri, Ofner, Silvio, Orain, David, Urwyler, Stephan
Published in Bioorganic & medicinal chemistry letters (01.06.2011)
Published in Bioorganic & medicinal chemistry letters (01.06.2011)
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Mechanisms of allosteric modulation at GABAB receptors by CGP7930 and GS39783: effects on affinities and efficacies of orthosteric ligands with distinct intrinsic properties
Urwyler, Stephan, Gjoni, Tina, Koljatić, Jelena, Dupuis, Delphine S
Published in Neuropharmacology (01.03.2005)
Published in Neuropharmacology (01.03.2005)
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6-Amino quinazolinedione sulfonamides as orally active competitive AMPA receptor antagonists
Orain, David, Ofner, Silvio, Koller, Manuel, Carcache, David A., Froestl, Wolfgang, Allgeier, Hans, Rasetti, Vittorio, Nozulak, Joachim, Mattes, Henri, Soldermann, Nicolas, Floersheim, Philipp, Desrayaud, Sandrine, Kallen, Joerg, Lingenhoehl, Kurt, Urwyler, Stephan
Published in Bioorganic & medicinal chemistry letters (15.01.2012)
Published in Bioorganic & medicinal chemistry letters (15.01.2012)
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