Highly efficient intercellular spreading of protein misfolding mediated by viral ligand-receptor interactions
Liu, Shu, Hossinger, André, Heumüller, Stefanie-Elisabeth, Hornberger, Annika, Buravlova, Oleksandra, Konstantoulea, Katerina, Müller, Stephan A., Paulsen, Lydia, Rousseau, Frederic, Schymkowitz, Joost, Lichtenthaler, Stefan F., Neumann, Manuela, Denner, Philip, Vorberg, Ina M.
Published in Nature communications (19.10.2021)
Published in Nature communications (19.10.2021)
Get full text
Journal Article
Loss of TREM2 function increases amyloid seeding but reduces plaque-associated ApoE
Parhizkar, Samira, Arzberger, Thomas, Brendel, Matthias, Kleinberger, Gernot, Deussing, Maximilian, Focke, Carola, Nuscher, Brigitte, Xiong, Monica, Ghasemigharagoz, Alireza, Katzmarski, Natalie, Krasemann, Susanne, Lichtenthaler, Stefan F., Müller, Stephan A., Colombo, Alessio, Monasor, Laura Sebastian, Tahirovic, Sabina, Herms, Jochen, Willem, Michael, Pettkus, Nadine, Butovsky, Oleg, Bartenstein, Peter, Edbauer, Dieter, Rominger, Axel, Ertürk, Ali, Grathwohl, Stefan A., Neher, Jonas J., Holtzman, David M., Meyer-Luehmann, Melanie, Haass, Christian
Published in Nature neuroscience (01.02.2019)
Published in Nature neuroscience (01.02.2019)
Get full text
Journal Article
Cell-type-specific profiling of brain mitochondria reveals functional and molecular diversity
Fecher, Caroline, Trovò, Laura, Müller, Stephan A., Snaidero, Nicolas, Wettmarshausen, Jennifer, Heink, Sylvia, Ortiz, Oskar, Wagner, Ingrid, Kühn, Ralf, Hartmann, Jana, Karl, Rosa Maria, Konnerth, Arthur, Korn, Thomas, Wurst, Wolfgang, Merkler, Doron, Lichtenthaler, Stefan F., Perocchi, Fabiana, Misgeld, Thomas
Published in Nature neuroscience (01.10.2019)
Published in Nature neuroscience (01.10.2019)
Get full text
Journal Article
The evolution of morals under indirect reciprocity
Gaudeul, Alexia, Keser, Claudia, Müller, Stephan
Published in Games and economic behavior (01.03.2021)
Published in Games and economic behavior (01.03.2021)
Get full text
Journal Article
Pro-inflammatory activation following demyelination is required for myelin clearance and oligodendrogenesis
Cunha, Maria Inês, Su, Minhui, Cantuti-Castelvetri, Ludovico, Müller, Stephan A, Schifferer, Martina, Djannatian, Minou, Alexopoulos, Ioannis, van der Meer, Franziska, Winkler, Anne, van Ham, Tjakko J, Schmid, Bettina, Lichtenthaler, Stefan F, Stadelmann, Christine, Simons, Mikael
Published in The Journal of experimental medicine (04.05.2020)
Published in The Journal of experimental medicine (04.05.2020)
Get full text
Journal Article
Loss of NPC1 enhances phagocytic uptake and impairs lipid trafficking in microglia
Colombo, Alessio, Dinkel, Lina, Müller, Stephan A., Sebastian Monasor, Laura, Schifferer, Martina, Cantuti-Castelvetri, Ludovico, König, Jasmin, Vidatic, Lea, Bremova-Ertl, Tatiana, Lieberman, Andrew P., Hecimovic, Silva, Simons, Mikael, Lichtenthaler, Stefan F., Strupp, Michael, Schneider, Susanne A., Tahirovic, Sabina
Published in Nature communications (24.02.2021)
Published in Nature communications (24.02.2021)
Get full text
Journal Article
Fibrillar Aβ triggers microglial proteome alterations and dysfunction in Alzheimer mouse models
Sebastian Monasor, Laura, Müller, Stephan A, Colombo, Alessio Vittorio, Tanrioever, Gaye, König, Jasmin, Roth, Stefan, Liesz, Arthur, Berghofer, Anna, Piechotta, Anke, Prestel, Matthias, Saito, Takashi, Saido, Takaomi C, Herms, Jochen, Willem, Michael, Haass, Christian, Lichtenthaler, Stefan F, Tahirovic, Sabina
Published in eLife (08.06.2020)
Published in eLife (08.06.2020)
Get full text
Journal Article
Reactivated endogenous retroviruses promote protein aggregate spreading
Liu, Shu, Heumüller, Stefanie-Elisabeth, Hossinger, André, Müller, Stephan A., Buravlova, Oleksandra, Lichtenthaler, Stefan F., Denner, Philip, Vorberg, Ina M.
Published in Nature communications (18.08.2023)
Published in Nature communications (18.08.2023)
Get full text
Journal Article
Discovery of 3‑Pyridyl Isoindolin-1-one Derivatives as Potent, Selective, and Orally Active Aldosterone Synthase (CYP11B2) Inhibitors
Liu, Yongfu, Wu, Jun, Zhou, Mingwei, Chen, Wenming, Li, Dongbo, Wang, Zhanguo, Hornsperger, Benoit, Aebi, Johannes D, Märki, Hans-Peter, Kuhn, Bernd, Wang, Lisha, Kuglstatter, Andreas, Benz, Jörg, Müller, Stephan, Hochstrasser, Remo, Ottaviani, Giorgio, Xin, Jian, Kirchner, Stephan, Mohr, Susanne, Verry, Philippe, Riboulet, William, Shen, Hong C, Mayweg, Alexander V, Amrein, Kurt, Tan, Xuefei
Published in Journal of medicinal chemistry (09.07.2020)
Published in Journal of medicinal chemistry (09.07.2020)
Get full text
Journal Article
The Alzheimer's disease-linked protease BACE1 modulates neuronal IL-6 signaling through shedding of the receptor gp130
Müller, Stephan A, Shmueli, Merav D, Feng, Xiao, Tüshaus, Johanna, Schumacher, Neele, Clark, Ryan, Smith, Brad E, Chi, An, Rose-John, Stefan, Kennedy, Matthew E, Lichtenthaler, Stefan F
Published in Molecular neurodegeneration (21.02.2023)
Published in Molecular neurodegeneration (21.02.2023)
Get full text
Journal Article
The Effect of Free and Protein-Bound Maillard Reaction Products N-ε-Carboxymethyllysine, N-ε-Fructosyllysine, and Pyrraline on Nrf2 and NFκB in HCT 116 Cells
Raupbach, Jana, Müller, Stephan K, Schnell, Vanessa, Friedrich, Suse, Hellwig, Anne, Grune, Tilman, Henle, Thomas
Published in Molecular nutrition & food research (01.09.2023)
Published in Molecular nutrition & food research (01.09.2023)
Get full text
Journal Article
An optimized quantitative proteomics method establishes the cell type‐resolved mouse brain secretome
Tüshaus, Johanna, Müller, Stephan A, Kataka, Evans Sioma, Zaucha, Jan, Sebastian Monasor, Laura, Su, Minhui, Güner, Gökhan, Jocher, Georg, Tahirovic, Sabina, Frishman, Dmitrij, Simons, Mikael, Lichtenthaler, Stefan F
Published in The EMBO journal (15.10.2020)
Published in The EMBO journal (15.10.2020)
Get full text
Journal Article
Signatures of glial activity can be detected in the CSF proteome
Eninger, Timo, Müller, Stephan A, Bacioglu, Mehtap, Schweighauser, Manuel, Lambert, Marius, Maia, Luis F, Neher, Jonas J, Hornfeck, Sarah M, Obermüller, Ulrike, Kleinberger, Gernot, Haass, Christian, Kahle, Philipp J, Staufenbiel, Matthias, Ping, Lingyan, Duong, Duc M, Levey, Allan I, Seyfried, Nicholas T, Lichtenthaler, Stefan F, Jucker, Mathias, Kaeser, Stephan A
Published in Proceedings of the National Academy of Sciences - PNAS (14.06.2022)
Published in Proceedings of the National Academy of Sciences - PNAS (14.06.2022)
Get full text
Journal Article
High Cytotoxic Efficiency of Lentivirally and Alpharetrovirally Engineered CD19-Specific Chimeric Antigen Receptor Natural Killer Cells Against Acute Lymphoblastic Leukemia
Müller, Stephan, Bexte, Tobias, Gebel, Veronika, Kalensee, Franziska, Stolzenberg, Eva, Hartmann, Jessica, Koehl, Ulrike, Schambach, Axel, Wels, Winfried S, Modlich, Ute, Ullrich, Evelyn
Published in Frontiers in immunology (24.01.2020)
Published in Frontiers in immunology (24.01.2020)
Get full text
Journal Article
Cleavage efficiency of the intramembrane protease γ‐secretase is reduced by the palmitoylation of a substrate's transmembrane domain
Aßfalg, Marlene, Güner, Gökhan, Müller, Stephan A., Breimann, Stephan, Langosch, Dieter, Muhle‐Goll, Claudia, Frishman, Dmitrij, Steiner, Harald, Lichtenthaler, Stefan F.
Published in The FASEB journal (01.02.2024)
Published in The FASEB journal (01.02.2024)
Get full text
Journal Article