Overcoming intrinsic multidrug resistance in melanoma by blocking the mitochondrial respiratory chain of slow-cycling JARID1B(high) cells
Roesch, Alexander, Vultur, Adina, Bogeski, Ivan, Wang, Huan, Zimmermann, Katharina M, Speicher, David, Körbel, Christina, Laschke, Matthias W, Gimotty, Phyllis A, Philipp, Stephan E, Krause, Elmar, Pätzold, Sylvie, Villanueva, Jessie, Krepler, Clemens, Fukunaga-Kalabis, Mizuho, Hoth, Markus, Bastian, Boris C, Vogt, Thomas, Herlyn, Meenhard
Published in Cancer cell (10.06.2013)
Published in Cancer cell (10.06.2013)
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Journal Article
Directed Evolution of Piperazic Acid Incorporation by a Nonribosomal Peptide Synthetase
Stephan, Philipp, Langley, Chloe, Winkler, Daniela, Basquin, Jérôme, Caputi, Lorenzo, O'Connor, Sarah E., Kries, Hajo
Published in Angewandte Chemie International Edition (28.08.2023)
Published in Angewandte Chemie International Edition (28.08.2023)
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Early long-term administration of the CSF1R inhibitor PLX3397 ablates microglia and reduces accumulation of intraneuronal amyloid, neuritic plaque deposition and pre-fibrillar oligomers in 5XFAD mouse model of Alzheimer's disease
Sosna, Justyna, Philipp, Stephan, Albay, 3rd, Ricardo, Reyes-Ruiz, Jorge Mauricio, Baglietto-Vargas, David, LaFerla, Frank M, Glabe, Charles G
Published in Molecular neurodegeneration (01.03.2018)
Published in Molecular neurodegeneration (01.03.2018)
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Journal Article
Analysing Megasynthetase Mutants at High Throughput Using Droplet Microfluidics
Pourmasoumi, Farzaneh, Hengoju, Sundar, Beck, Katharina, Stephan, Philipp, Klopfleisch, Lukas, Hoernke, Maria, Rosenbaum, Miriam A., Kries, Hajo
Published in Chembiochem : a European journal of chemical biology (14.12.2023)
Published in Chembiochem : a European journal of chemical biology (14.12.2023)
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Journal Article
Cavβ3 Regulates Ca2+ Signaling and Insulin Expression in Pancreatic β-Cells in a Cell-Autonomous Manner
Becker, Alexander, Wardas, Barbara, Salah, Houssein, Amini, Maryam, Fecher-Trost, Claudia, Sen, Qiao, Martus, Damian, Beck, Andreas, Philipp, Stephan E., Flockerzi, Veit, Belkacemi, Anouar
Published in Diabetes (New York, N.Y.) (01.11.2021)
Published in Diabetes (New York, N.Y.) (01.11.2021)
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Journal Article
Deletion of TRPC4 and TRPC6 in mice impairs smooth muscle contraction and intestinal motility in vivo
Tsvilovskyy, Volodymyr V, Zholos, Alexander V, Aberle, Thomas, Philipp, Stephan E, Dietrich, Alexander, Zhu, Michael X, Birnbaumer, Lutz, Freichel, Marc, Flockerzi, Veit
Published in Gastroenterology (New York, N.Y. 1943) (01.10.2009)
Published in Gastroenterology (New York, N.Y. 1943) (01.10.2009)
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Journal Article
Precursor‐Directed Diversification of Cyclic Tetrapeptidic Pseudoxylallemycins
Guo, Huijuan, Schmidt, Alexander, Stephan, Philipp, Raguž, Luka, Braga, Daniel, Kaiser, Marcel, Dahse, Hans‐Martin, Weigel, Christiane, Lackner, Gerald, Beemelmanns, Christine
Published in Chembiochem : a European journal of chemical biology (02.11.2018)
Published in Chembiochem : a European journal of chemical biology (02.11.2018)
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Journal Article
Anti-nociceptive action of peripheral mu-opioid receptors by G-beta-gamma protein-mediated inhibition of TRPM3 channels
Dembla, Sandeep, Behrendt, Marc, Mohr, Florian, Goecke, Christian, Sondermann, Julia, Schneider, Franziska M, Schmidt, Marlene, Stab, Julia, Enzeroth, Raissa, Leitner, Michael G, Nuñez-Badinez, Paulina, Schwenk, Jochen, Nürnberg, Bernd, Cohen, Alejandro, Philipp, Stephan E, Greffrath, Wolfgang, Bünemann, Moritz, Oliver, Dominik, Zakharian, Eleonora, Schmidt, Manuela, Oberwinkler, Johannes
Published in eLife (15.08.2017)
Published in eLife (15.08.2017)
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Structure-based inhibitors of amyloid beta core suggest a common interface with tau
Griner, Sarah L, Seidler, Paul, Bowler, Jeannette, Murray, Kevin A, Yang, Tianxiao Peter, Sahay, Shruti, Sawaya, Michael R, Cascio, Duilio, Rodriguez, Jose A, Philipp, Stephan, Sosna, Justyna, Glabe, Charles G, Gonen, Tamir, Eisenberg, David S
Published in eLife (15.10.2019)
Published in eLife (15.10.2019)
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Journal Article
Transient receptor potential M3 channels are ionotropic steroid receptors in pancreatic β cells
Lis, Annette, Lambert, Sachar, Straub, Isabelle, Mannebach, Stefanie, Flockerzi, Veit, Philipp, Stephan E, Wagner, Thomas F.J, Mathar, Ilka, Düfer, Martina, Oberwinkler, Johannes, Loch, Sabine
Published in Nature cell biology (01.12.2008)
Published in Nature cell biology (01.12.2008)
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Journal Article
The structural basis for an on–off switch controlling Gβγ-mediated inhibition of TRPM3 channels
Behrendt, Marc, Gruss, Fabian, Enzeroth, Raissa, Dembla, Sandeep, Zhao, Siyuan, Crassous, Pierre-Antoine, Mohr, Florian, Nys, Mieke, Louros, Nikolaos, Gallardo, Rodrigo, Zorzinif, Valentina, Wagner, Doris, Economou, Anastassios, Οικoνόμoυ, Αναστάσιoς, Rousseau, Frederic, Schymkowitz, Joost, Philipp, Stephan E., Rohacs, Tibor, Ulens, Chris, Oberwinkler, Johannes
Published in Proceedings of the National Academy of Sciences - PNAS (17.11.2020)
Published in Proceedings of the National Academy of Sciences - PNAS (17.11.2020)
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Journal Article
A background Ca2+ entry pathway mediated by TRPC1/TRPC4 is critical for development of pathological cardiac remodelling
Camacho Londoño, Juan E, Tian, Qinghai, Hammer, Karin, Schröder, Laura, Camacho Londoño, Julia, Reil, Jan C, He, Tao, Oberhofer, Martin, Mannebach, Stefanie, Mathar, Ilka, Philipp, Stephan E, Tabellion, Wiebke, Schweda, Frank, Dietrich, Alexander, Kaestner, Lars, Laufs, Ulrich, Birnbaumer, Lutz, Flockerzi, Veit, Freichel, Marc, Lipp, Peter
Published in European heart journal (01.09.2015)
Published in European heart journal (01.09.2015)
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Journal Article
Increased IgE-dependent mast cell activation and anaphylactic responses in mice lacking the calcium-activated nonselective cation channel TRPM4
Vennekens, Rudi, Freichel, Marc, Olausson, Jenny, Meissner, Marcel, Bloch, Wilhelm, Mathar, Ilka, Philipp, Stephan E, Schmitz, Frank, Weissgerber, Petra, Nilius, Bernd, Flockerzi, Veit
Published in Nature Immunology (01.03.2007)
Published in Nature Immunology (01.03.2007)
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Journal Article
The S4–S5-linker – gearbox of TRP channel gating
Hofmann, Laura, Wang, Hongmei, Zheng, Wang, Philipp, Stephan E, Hidalgo, Patricia, Cavalié, Adolfo, Chen, Xing-Zhen, Beck, Andreas, Flockerzi, Veit
Published in Cell calcium (Edinburgh) (01.11.2017)
Published in Cell calcium (Edinburgh) (01.11.2017)
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Journal Article
Ca2+-dependent regulation and binding of calmodulin to multiple sites of Transient Receptor Potential Melastatin 3 (TRPM3) ion channels
Przibilla, Julia, Dembla, Sandeep, Rizun, Oleksandr, Lis, Annette, Jung, Martin, Oberwinkler, Johannes, Beck, Andreas, Philipp, Stephan E.
Published in Cell calcium (Edinburgh) (01.07.2018)
Published in Cell calcium (Edinburgh) (01.07.2018)
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Journal Article
Identification of Sidt2 as a lysosomal cation‐conducting protein
Beck, Andreas, Fecher‐Trost, Claudia, Wolske, Karin, Philipp, Stephan E., Flockerzi, Veit, Wissenbach, Ulrich
Published in FEBS letters (01.01.2017)
Published in FEBS letters (01.01.2017)
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Journal Article
Morphologically homogeneous red blood cells present a heterogeneous response to hormonal stimulation
Wang, Jue, Wagner-Britz, Lisa, Bogdanova, Anna, Ruppenthal, Sandra, Wiesen, Kathrina, Kaiser, Elisabeth, Tian, Qinghai, Krause, Elmar, Bernhardt, Ingolf, Lipp, Peter, Philipp, Stephan E, Kaestner, Lars
Published in PloS one (28.06.2013)
Published in PloS one (28.06.2013)
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