Thermoneutral housing exacerbates nonalcoholic fatty liver disease in mice and allows for sex-independent disease modeling
Giles, Daniel A, Moreno-Fernandez, Maria E, Stankiewicz, Traci E, Graspeuntner, Simon, Cappelletti, Monica, Wu, David, Mukherjee, Rajib, Chan, Calvin C, Lawson, Matthew J, Klarquist, Jared, Sünderhauf, Annika, Softic, Samir, Kahn, C Ronald, Stemmer, Kerstin, Iwakura, Yoichiro, Aronow, Bruce J, Karns, Rebekah, Steinbrecher, Kris A, Karp, Christopher L, Sheridan, Rachel, Shanmukhappa, Shiva K, Reynaud, Damien, Haslam, David B, Sina, Christian, Rupp, Jan, Hogan, Simon P, Divanovic, Senad
Published in Nature medicine (01.07.2017)
Published in Nature medicine (01.07.2017)
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Diabetes as risk factor for pancreatic cancer: Hyperglycemia promotes epithelial-mesenchymal-transition and stem cell properties in pancreatic ductal epithelial cells
Rahn, Sascha, Zimmermann, Vivien, Viol, Fabrice, Knaack, Hendrike, Stemmer, Kerstin, Peters, Lena, Lenk, Lennart, Ungefroren, Hendrik, Saur, Dieter, Schäfer, Heiner, Helm, Ole, Sebens, Susanne
Published in Cancer letters (28.02.2018)
Published in Cancer letters (28.02.2018)
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Journal Article
The scaffold protein p62 regulates adaptive thermogenesis through ATF2 nuclear target activation
Fischer, Katrin, Fenzl, Anna, Liu, Dianxin, Dyar, Kenneth A, Kleinert, Maximilian, Brielmeier, Markus, Clemmensen, Christoffer, Fedl, Anna, Finan, Brian, Gessner, Andre, Jastroch, Martin, Huang, Jianfeng, Keipert, Susanne, Klingenspor, Martin, Brüning, Jens C, Kneilling, Manfred, Maier, Florian C, Othman, Ahmed E, Pichler, Bernd J, Pramme-Steinwachs, Ines, Sachs, Stephan, Scheideler, Angelika, Thaiss, Wolfgang M, Uhlenhaut, Henriette, Ussar, Siegfried, Woods, Stephen C, Zorn, Julia, Stemmer, Kerstin, Collins, Sheila, Diaz-Meco, Maria, Moscat, Jorge, Tschöp, Matthias H, Müller, Timo D
Published in Nature communications (08.05.2020)
Published in Nature communications (08.05.2020)
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Journal Article
Comparison of Aristolochic acid I derived DNA adduct levels in human renal toxicity models
Bastek, Heinke, Zubel, Tabea, Stemmer, Kerstin, Mangerich, Aswin, Beneke, Sascha, Dietrich, Daniel R.
Published in Toxicology (Amsterdam) (15.05.2019)
Published in Toxicology (Amsterdam) (15.05.2019)
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Journal Article
Liver microRNA transcriptome reveals miR-182 as link between type 2 diabetes and fatty liver disease in obesity
Krause, Christin, Britsemmer, Jan H, Bernecker, Miriam, Molenaar, Anna, Taege, Natalie, Lopez-Alcantara, Nuria, Geißler, Cathleen, Kaehler, Meike, Iben, Katharina, Judycka, Anna, Wagner, Jonas, Wolter, Stefan, Mann, Oliver, Pfluger, Paul, Cascorbi, Ingolf, Lehnert, Hendrik, Stemmer, Kerstin, Schriever, Sonja C, Kirchner, Henriette
Published in eLife (22.07.2024)
Published in eLife (22.07.2024)
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Journal Article
Adipocyte-derived extracellular vesicles increase insulin secretion through transport of insulinotropic protein cargo
Kulaj, Konxhe, Harger, Alexandra, Bauer, Michaela, Caliskan, Özüm S, Gupta, Tilak Kumar, Chiang, Dapi Menglin, Milbank, Edward, Reber, Josefine, Karlas, Angelos, Kotzbeck, Petra, Sailer, David N, Volta, Francesco, Lutter, Dominik, Prakash, Sneha, Merl-Pham, Juliane, Ntziachristos, Vasilis, Hauner, Hans, Pfaffl, Michael W, Tschöp, Matthias H, Müller, Timo D, Hauck, Stefanie M, Engel, Benjamin D, Gerdes, Jantje M, Pfluger, Paul T, Krahmer, Natalie, Stemmer, Kerstin
Published in Nature communications (09.02.2023)
Published in Nature communications (09.02.2023)
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Journal Article
Fibroblast Growth Factor 21 Mediates Specific Glucagon Actions
HABEGGER, Kirk M, STEMMER, Kerstin, KRISHNA, Radha, ARAFAT, Ayman M, KONKAR, Anish, BELLI, Sara, KAPPS, Martin, WOODS, Stephen C, HOFMANN, Susanna M, D'ALESSIO, David, PFLUGER, Paul T, PEREZ-TILVE, Diego, CHENG, Christine, SEELEY, Randy J, KONISHI, Morichika, ITOH, Nobuyujki, KHARITONENKOV, Alexei, SPRANGER, Joachim, DIMARCHI, Richard D, TSCHÖP, Matthias H, MÜLLER, Timo D, HEPPNER, Kristy M, OTTAWAY, Nickki, HOLLAND, Jenna, HEMBREE, Jazzminn L, SMILEY, David, GELFANOV, Vasily
Published in Diabetes (New York, N.Y.) (01.05.2013)
Published in Diabetes (New York, N.Y.) (01.05.2013)
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Spatiotemporal GLP-1 and GIP receptor signaling and trafficking/recycling dynamics induced by selected receptor mono- and dual-agonists
Novikoff, Aaron, O'Brien, Shannon L., Bernecker, Miriam, Grandl, Gerald, Kleinert, Maximilian, Knerr, Patrick J., Stemmer, Kerstin, Klingenspor, Martin, Zeigerer, Anja, DiMarchi, Richard, Tschöp, Matthias H., Finan, Brian, Calebiro, Davide, Müller, Timo D.
Published in Molecular metabolism (Germany) (01.07.2021)
Published in Molecular metabolism (Germany) (01.07.2021)
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Journal Article
Adipose cells and tissues soften with lipid accumulation while in diabetes adipose tissue stiffens
Abuhattum, Shada, Kotzbeck, Petra, Schlüßler, Raimund, Harger, Alexandra, Ariza de Schellenberger, Angela, Kim, Kyoohyun, Escolano, Joan-Carles, Müller, Torsten, Braun, Jürgen, Wabitsch, Martin, Tschöp, Matthias, Sack, Ingolf, Brankatschk, Marko, Guck, Jochen, Stemmer, Kerstin, Taubenberger, Anna V
Published in Scientific reports (20.06.2022)
Published in Scientific reports (20.06.2022)
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Journal Article
Hypothalamic leptin action is mediated by histone deacetylase 5
Kabra, Dhiraj G, Pfuhlmann, Katrin, García-Cáceres, Cristina, Schriever, Sonja C, Casquero García, Veronica, Kebede, Adam Fiseha, Fuente-Martin, Esther, Trivedi, Chitrang, Heppner, Kristy, Uhlenhaut, N Henriette, Legutko, Beata, Kabra, Uma D, Gao, Yuanqing, Yi, Chun-Xia, Quarta, Carmelo, Clemmensen, Christoffer, Finan, Brian, Müller, Timo D, Meyer, Carola W, Paez-Pereda, Marcelo, Stemmer, Kerstin, Woods, Stephen C, Perez-Tilve, Diego, Schneider, Robert, Olson, Eric N, Tschöp, Matthias H, Pfluger, Paul T
Published in Nature communications (29.02.2016)
Published in Nature communications (29.02.2016)
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Journal Article
Pharmacological targeting of α3β4 nicotinic receptors improves peripheral insulin sensitivity in mice with diet-induced obesity
Jall, Sigrid, De Angelis, Meri, Lundsgaard, Anne-Marie, Fritzen, Andreas M., Nicolaisen, Trine S., Klein, Anders B., Novikoff, Aaron, Sachs, Stephan, Richter, Erik A., Kiens, Bente, Schramm, Karl-Werner, Tschöp, Matthias H., Stemmer, Kerstin, Clemmensen, Christoffer, Müller, Timo D., Kleinert, Maximilian
Published in Diabetologia (01.06.2020)
Published in Diabetologia (01.06.2020)
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Journal Article
Vertical sleeve gastrectomy triggers fast β-cell recovery upon overt diabetes
Oppenländer, Lena, Palit, Subarna, Stemmer, Kerstin, Greisle, Tobias, Sterr, Michael, Salinno, Ciro, Bastidas-Ponce, Aimée, Feuchtinger, Annette, Böttcher, Anika, Ansarullah, Theis, Fabian J., Lickert, Heiko
Published in Molecular metabolism (Germany) (01.12.2021)
Published in Molecular metabolism (Germany) (01.12.2021)
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Journal Article
Impaired glucose tolerance in rats fed low-carbohydrate, high-fat diets
Bielohuby, Maximilian, Sisley, Stephanie, Sandoval, Darleen, Herbach, Nadja, Zengin, Ayse, Fischereder, Michael, Menhofer, Dominik, Stoehr, Barbara J M, Stemmer, Kerstin, Wanke, Rüdiger, Tschöp, Matthias H, Seeley, Randy J, Bidlingmaier, Martin
Published in American journal of physiology: endocrinology and metabolism (01.11.2013)
Published in American journal of physiology: endocrinology and metabolism (01.11.2013)
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Journal Article
Dual specificity phosphatase 6 deficiency is associated with impaired systemic glucose tolerance and reversible weight retardation in mice
Pfuhlmann, Katrin, Pfluger, Paul T, Schriever, Sonja C, Müller, Timo D, Tschöp, Matthias H, Stemmer, Kerstin
Published in PloS one (05.09.2017)
Published in PloS one (05.09.2017)
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Journal Article
The orphan receptor Gpr83 regulates systemic energy metabolism via ghrelin-dependent and ghrelin-independent mechanisms
Müller, Timo D, Müller, Anne, Yi, Chun-Xia, Habegger, Kirk M, Meyer, Carola W, Gaylinn, Bruce D, Finan, Brian, Heppner, Kristy, Trivedi, Chitrang, Bielohuby, Maximilian, Abplanalp, William, Meyer, Franziska, Piechowski, Carolin L, Pratzka, Juliane, Stemmer, Kerstin, Holland, Jenna, Hembree, Jazzmin, Bhardwaj, Nakul, Raver, Christine, Ottaway, Nickki, Krishna, Radha, Sah, Renu, Sallee, Floyd R, Woods, Stephen C, Perez-Tilve, Diego, Bidlingmaier, Martin, Thorner, Michael O, Krude, Heiko, Smiley, David, DiMarchi, Richard, Hofmann, Susanna, Pfluger, Paul T, Kleinau, Gunnar, Biebermann, Heike, Tschöp, Matthias H
Published in Nature communications (07.06.2013)
Published in Nature communications (07.06.2013)
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Journal Article
Induction of ketosis in rats fed low-carbohydrate, high-fat diets depends on the relative abundance of dietary fat and protein
Bielohuby, Maximilian, Menhofer, Dominik, Kirchner, Henriette, Stoehr, Barbara J M, Müller, Timo D, Stock, Peggy, Hempel, Madlen, Stemmer, Kerstin, Pfluger, Paul T, Kienzle, Ellen, Christ, Bruno, Tschöp, Matthias H, Bidlingmaier, Martin
Published in American journal of physiology: endocrinology and metabolism (01.01.2011)
Published in American journal of physiology: endocrinology and metabolism (01.01.2011)
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Journal Article
High-fat-diet-induced obesity causes an inflammatory and tumor-promoting microenvironment in the rat kidney
Stemmer, Kerstin, Perez-Tilve, Diego, Ananthakrishnan, Gayathri, Bort, Anja, Seeley, Randy J, Tschöp, Matthias H, Dietrich, Daniel R, Pfluger, Paul T
Published in Disease models & mechanisms (01.09.2012)
Published in Disease models & mechanisms (01.09.2012)
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Journal Article
The glucose-dependent insulinotropic polypeptide (GIP) regulates body weight and food intake via CNS-GIPR signaling
Zhang, Qian, Delessa, Challa Tenagne, Augustin, Robert, Bakhti, Mostafa, Colldén, Gustav, Drucker, Daniel J., Feuchtinger, Annette, Caceres, Cristina Garcia, Grandl, Gerald, Harger, Alexandra, Herzig, Stephan, Hofmann, Susanna, Holleman, Cassie Lynn, Jastroch, Martin, Keipert, Susanne, Kleinert, Maximilian, Knerr, Patrick J., Kulaj, Konxhe, Legutko, Beata, Lickert, Heiko, Liu, Xue, Luippold, Gerd, Lutter, Dominik, Malogajski, Emilija, Medina, Marta Tarquis, Mowery, Stephanie A., Blutke, Andreas, Perez-Tilve, Diego, Salinno, Ciro, Sehrer, Laura, DiMarchi, Richard D., Tschöp, Matthias H., Stemmer, Kerstin, Finan, Brian, Wolfrum, Christian, Müller, Timo D.
Published in Cell metabolism (06.04.2021)
Published in Cell metabolism (06.04.2021)
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