Stromal-derived interleukin 6 drives epithelial-to-mesenchymal transition and therapy resistance in esophageal adenocarcinoma
Ebbing, Eva A., van der Zalm, Amber P., Steins, Anne, Creemers, Aafke, Hermsen, Simone, Rentenaar, Rosa, Klein, Michelle, Waasdorp, Cynthia, Hooijer, Gerrit K. J., Meijer, Sybren L., Krishnadath, Kausilia K., Punt, Cornelis J. A., van Berge Henegouwen, Mark I., Gisbertz, Suzanne S., van Delden, Otto M., Hulshof, Maarten C. C. M., Medema, Jan Paul, van Laarhoven, Hanneke W. M., Bijlsma, Maarten F.
Published in Proceedings of the National Academy of Sciences - PNAS (05.02.2019)
Published in Proceedings of the National Academy of Sciences - PNAS (05.02.2019)
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Journal Article
Computational modeling of heart failure in microgravity transitions
Wilson, Stefan L, Schulte, Klaus-Martin, Steins, Anne, Gruen, Russell L, Tucker, Emma M, van Loon, Lex M
Published in Frontiers in physiology (21.06.2024)
Published in Frontiers in physiology (21.06.2024)
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Journal Article
High‐grade mesenchymal pancreatic ductal adenocarcinoma drives stromal deactivation through CSF‐1
Steins, Anne, van Mackelenbergh, Madelaine G, van der Zalm, Amber P, Klaassen, Remy, Serrels, Bryan, Goris, Sandrine G, Kocher, Hemant M, Waasdorp, Cynthia, de Jong, Joan H, Tekin, Cansu, Besselink, Marc G, Busch, Olivier R, van de Vijver, Marc J, Verheij, Joanne, Dijk, Frederike, van Tienhoven, Geertjan, Wilmink, Johanna W, Medema, Jan Paul, van Laarhoven, Hanneke WM, Bijlsma, Maarten F
Published in EMBO reports (06.05.2020)
Published in EMBO reports (06.05.2020)
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Journal Article
Computational modeling of orthostatic intolerance for travel to Mars
van Loon, Lex M., Steins, Anne, Schulte, Klaus-Martin, Gruen, Russell, Tucker, Emma M.
Published in NPJ microgravity (09.08.2022)
Published in NPJ microgravity (09.08.2022)
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Journal Article
Pathological validation and prognostic potential of quantitative MRI in the characterization of pancreas cancer: preliminary experience
Klaassen, Remy, Steins, Anne, Gurney‐Champion, Oliver J., Bijlsma, Maarten F., Tienhoven, Geertjan, Engelbrecht, Marc R. W., Eijck, Casper H. J., Suker, Mustafa, Wilmink, Johanna W., Besselink, Marc G., Busch, Olivier R., Boer, Onno J., Vijver, Marc J., Hooijer, Gerrit K. J., Verheij, Joanne, Stoker, Jaap, Nederveen, Aart J., Laarhoven, Hanneke W. M.
Published in Molecular oncology (01.09.2020)
Published in Molecular oncology (01.09.2020)
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Journal Article
Stromal SPOCK1 supports invasive pancreatic cancer growth
Veenstra, Veronique L., Damhofer, Helene, Waasdorp, Cynthia, Steins, Anne, Kocher, Hemant M., Medema, Jan P., Laarhoven, Hanneke W., Bijlsma, Maarten F
Published in Molecular oncology (01.08.2017)
Published in Molecular oncology (01.08.2017)
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Journal Article
In Vitro Evaluation of Spider Silk Meshes as a Potential Biomaterial for Bladder Reconstruction
Steins, Anne, Dik, Pieter, Müller, Wally H, Vervoort, Stephin J, Reimers, Kerstin, Kuhbier, Jörn W, Vogt, Peter M, van Apeldoorn, Aart A, Coffer, Paul J, Schepers, Koen
Published in PloS one (21.12.2015)
Published in PloS one (21.12.2015)
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Journal Article
Rapid stromal remodeling by short‐term VEGFR2 inhibition increases chemotherapy delivery in esophagogastric adenocarcinoma
Steins, Anne, Klaassen, Remy, Jacobs, Igor, Schabel, Matthias C., Lier, Monique G. J. T. B., Ebbing, Eva A., Hectors, Stefanie J., Tas, Sander W., Maracle, Chrissta X., Punt, Cornelis J. A., Siebes, Maria, Bergman, Jacques J. G. H. M., Medema, Jan Paul, Wilmink, Johanna W., Mathot, Ron A. A., Strijkers, Gustav J., Bijlsma, Maarten F., Laarhoven, Hanneke W. M.
Published in Molecular oncology (01.04.2020)
Published in Molecular oncology (01.04.2020)
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Journal Article
Soluble Compounds Released by Hypoxic Stroma Confer Invasive Properties to Pancreatic Ductal Adenocarcinoma
Liu, Dajia, Steins, Anne, Klaassen, Remy, van der Zalm, Amber P., Bennink, Roel J., van Tienhoven, Geertjan, Besselink, Marc G., Bijlsma, Maarten F., van Laarhoven, Hanneke W. M.
Published in Biomedicines (22.10.2020)
Published in Biomedicines (22.10.2020)
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Journal Article
Systemic effects of angiogenesis inhibition alter pharmacokinetics and intratumoral delivery of nab-paclitaxel
Steins, Anne, Ebbing, Eva A., Pistorius, Marcel C. M., Waasdorp, Cynthia, Krishnadath, Kausilia K., Medema, Jan Paul, Wilmink, Johanna W., Mathôt, Ron A. A., Bijlsma, Maarten F., van Laarhoven, Hanneke W. M.
Published in Drug delivery (2017)
Published in Drug delivery (2017)
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Journal Article
Establishment of patient-derived xenograft models and cell lines for malignancies of the upper gastrointestinal tract
Damhofer, Helene, Ebbing, Eva A, Steins, Anne, Welling, Lieke, Tol, Johanna A, Krishnadath, Kausilia K, van Leusden, Tom, van de Vijver, Marc J, Besselink, Marc G, Busch, Olivier R, Henegouwen, Mark I van Berge, van Delden, Otto, Meijer, Sybren L, Dijk, Frederike, Medema, Jan Paul, van Laarhoven, Hanneke W, Bijlsma, Maarten F
Published in Journal of translational medicine (11.04.2015)
Published in Journal of translational medicine (11.04.2015)
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Journal Article
Inhaled nebulised unfractionated heparin for the treatment of hospitalised patients with COVID‐19: A multicentre case series of 98 patients
Haren, Frank M. P., Loon, Lex M., Steins, Anne, Smoot, Thomas L., Sas, Caitlin, Staas, Sabrina, Vilaseca, Alicia B., Barbera, Ruben A., Vidmar, Gustavo, Beccari, Hugo, Popilevsky, Frida, Daribayeva, Eleonora, Venkatesan, Bhuvaneshwari, Mozes, Susan, Postel, Rachel, Popilevski, Natalie, Webb, Andrew, Nunes, Quentin, Laffey, John G., Artigas, Antonio, Smith, Roger, Dixon, Barry, Richardson, Alice, Yoon, Hwan‐Jin, Page, Clive
Published in British journal of clinical pharmacology (01.06.2022)
Published in British journal of clinical pharmacology (01.06.2022)
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Journal Article
Unsupervised class discovery in pancreatic ductal adenocarcinoma reveals cell-intrinsic mesenchymal features and high concordance between existing classification systems
Dijk, Frederike, Veenstra, Veronique L., Soer, Eline C., Dings, Mark P. G., Zhao, Lan, Halfwerk, Johannes B., Hooijer, Gerrit K., Damhofer, Helene, Marzano, Marco, Steins, Anne, Waasdorp, Cynthia, Busch, Olivier R., Besselink, Marc G., Tol, Johanna A., Welling, Lieke, van Rijssen, Lennart B., Klompmaker, Sjors, Wilmink, Hanneke W., van Laarhoven, Hanneke W., Medema, Jan Paul, Vermeulen, Louis, van Hooff , Sander R., Koster, Jan, Verheij, Joanne, van de Vijver, Marc J., Wang, Xin, Bijlsma, Maarten F.
Published in Scientific reports (15.01.2020)
Published in Scientific reports (15.01.2020)
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Journal Article
Esophageal Adenocarcinoma Cells and Xenograft Tumors Exposed to Erb-b2 Receptor Tyrosine Kinase 2 and 3 Inhibitors Activate Transforming Growth Factor Beta Signaling, Which Induces Epithelial to Mesenchymal Transition
Ebbing, Eva A, Steins, Anne, Fessler, Evelyn, Stathi, Phylicia, Lesterhuis, Willem Joost, Krishnadath, Kausilia K, Vermeulen, Louis, Medema, Jan Paul, Bijlsma, Maarten F, van Laarhoven, Hanneke W.M
Published in Gastroenterology (New York, N.Y. 1943) (01.07.2017)
Published in Gastroenterology (New York, N.Y. 1943) (01.07.2017)
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Journal Article
Chemoradiation induces epithelial‐to‐mesenchymal transition in esophageal adenocarcinoma
Steins, Anne, Ebbing, Eva A., Creemers, Aafke, Zalm, Amber P., Jibodh, Rajni A., Waasdorp, Cynthia, Meijer, Sybren L., Delden, Otto M., Krishnadath, Kausilia K., Hulshof, Maarten C.C.M., Bennink, Roelof J., Punt, Cornelis J.A., Medema, Jan Paul, Bijlsma, Maarten F., Laarhoven, Hanneke W.M.
Published in International journal of cancer (15.11.2019)
Published in International journal of cancer (15.11.2019)
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Journal Article
MP9-20 PRIMARY HUMAN UROTHELIAL CELL CULTURE ON A MATRIX OF SPIDER SILK; A NOVEL TECHNIQUE IN BLADDER RECONSTRUCTION
Steins, Anne, Dik, Pieter, van Apeldoorn, Aart, Reimers, Kerstin, Klijn, Aart, de Jong, Tom, Coffer, Paul, Schepers, Koen
Published in The Journal of urology (01.04.2014)
Published in The Journal of urology (01.04.2014)
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Journal Article
Cell death and barrier disruption by clinically used iodine concentrations
Steins, Anne, Carroll, Christina, Choong, Fui Jiun, George, Amee J, He, Jin-Shu, Parsons, Kate M, Feng, Shouya, Man, Si Ming, Kam, Cathelijne, van Loon, Lex M, Poh, Perlita, Ferreira, Rita, Mann, Graham J, Gruen, Russell L, Hannan, Katherine M, Hannan, Ross D, Schulte, Klaus-Martin
Published in Life science alliance (01.06.2023)
Published in Life science alliance (01.06.2023)
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Journal Article
Abstract 421: The role of the tumor microenvironment of pancreatic cancer to predict treatment outcome
Steins, Anne, Klaassen, Remy, Gurney-Champion, Oliver, Bijlsma, Maarten, Medema, Jan Paul, Wijkstra, Hessel, van Tienhoven, Geertjan, Busch, Olivier, Punt, Cornelis, Besselink, Marc, Wilmink, Hanneke, van de Vijver, Marc, Stoker, Jaap, Nederveen, Aart, van Laarhoven, Hanneke
Published in Cancer research (Chicago, Ill.) (01.08.2015)
Published in Cancer research (Chicago, Ill.) (01.08.2015)
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Journal Article
Establishment of patient-derived xenograft models and cell lines for malignancies of the upper gastrointestinal tract
Damhofer, Helene, Ebbing, Eva A, Steins, Anne, Welling, Lieke, Tol, Johanna A, Krishnadath, Kausilia K, van Leusden, Tom, van de Vijver, Marc J, Besselink, Marc G, Busch, Olivier R, van Berge Henegouwen, Mark I, van Delden, Otto, Meijer, Sybren L, Dijk, Frederike, Medema, Jan Paul, van Laarhoven, Hanneke W, Bijlsma, Maarten F
Published in Journal of translational medicine (11.04.2015)
Published in Journal of translational medicine (11.04.2015)
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Journal Article