Patient-derived organoids and orthotopic xenografts of primary and recurrent gliomas represent relevant patient avatars for precision oncology
Golebiewska, Anna, Hau, Ann-Christin, Oudin, Anaïs, Stieber, Daniel, Yabo, Yahaya A., Baus, Virginie, Barthelemy, Vanessa, Klein, Eliane, Bougnaud, Sébastien, Keunen, Olivier, Wantz, May, Michelucci, Alessandro, Neirinckx, Virginie, Muller, Arnaud, Kaoma, Tony, Nazarov, Petr V., Azuaje, Francisco, De Falco, Alfonso, Flies, Ben, Richart, Lorraine, Poovathingal, Suresh, Arns, Thais, Grzyb, Kamil, Mock, Andreas, Herold-Mende, Christel, Steino, Anne, Brown, Dennis, May, Patrick, Miletic, Hrvoje, Malta, Tathiane M., Noushmehr, Houtan, Kwon, Yong-Jun, Jahn, Winnie, Klink, Barbara, Tanner, Georgette, Stead, Lucy F., Mittelbronn, Michel, Skupin, Alexander, Hertel, Frank, Bjerkvig, Rolf, Niclou, Simone P.
Published in Acta neuropathologica (01.12.2020)
Published in Acta neuropathologica (01.12.2020)
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Oncofetal Chondroitin Sulfate: A Putative Therapeutic Target in Adult and Pediatric Solid Tumors
Khazamipour, Nastaran, Al-Nakouzi, Nader, Oo, Htoo Zarni, Ørum-Madsen, Maj, Steino, Anne, Sorensen, Poul H, Daugaard, Mads
Published in Cells (Basel, Switzerland) (28.03.2020)
Published in Cells (Basel, Switzerland) (28.03.2020)
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Phase 2 clinical trial of VAL-083 as first-line treatment in newly-diagnosed MGMT-unmethylated glioblastoma multiforme (GBM): Halfway report
Guo, Chengcheng, Yang, Qunying, Li, Jiawei, Wu, Shaoxiong, Deng, Meiling, Du, Xiaojing, Sai, Ke, Jiang, Xiaobing, Chen, Zhenghe, Zhang, Ji, Lin, Fuhua, Wang, Jian, Chen, Yinsheng, Ke, Chao, Zhang, Xiangheng, Ju, Xue, Mou, Yonggao, Bacha, Jeffrey, Steino, Anne, Kanekal, Sarath, Kwan, Claire, Johnson, Gregory, Schwartz, Richard, Langlands, John, Brown, Dennis, Chen, Zhong-ping
Published in Glioma (01.01.2019)
Published in Glioma (01.01.2019)
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Indoleamine 2,3-Dioxygenase Inhibitors Isolated from the Sponge Xestospongia vansoesti: Structure Elucidation, Analogue Synthesis, and Biological Activity
Centko, Ryan M., Steinø, Anne, Rosell, Federico I., Patrick, Brian O., de Voogd, Nicole, Mauk, A. Grant, Andersen, Raymond J.
Published in Organic letters (19.12.2014)
Published in Organic letters (19.12.2014)
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Abstract P053: VAL-083 (dianhydrogalactitol) synergizes with PARP inhibitors in BRCA-proficient and BRCA-deficient ovarian cancer models
Steino, Anne, He, Guangan, Zhai, Beibei, Bacha, Jeffrey, Brown, Dennis M., Daugaard, Mads, Siddik, Zahid H.
Published in Molecular cancer therapeutics (01.12.2021)
Published in Molecular cancer therapeutics (01.12.2021)
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Abstract 1369: Dianhydrogalactitol (VAL-083) synergizes with topoisomerase inhibitors to overcome homologous recombination repair activity in glioblastoma and prostate cancer cells
Zhai, Beibei, Kotapalli, Sudha Sravanti, Bacha, Jeffrey A., Brown, Dennis M., Steino, Anne, Daugaard, Mads
Published in Cancer research (Chicago, Ill.) (15.08.2020)
Published in Cancer research (Chicago, Ill.) (15.08.2020)
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Halicloic Acids A and B Isolated from the Marine Sponge Haliclona sp. Collected in the Philippines Inhibit Indoleamine 2,3-Dioxygenase
Williams, David E, Steinø, Anne, de Voogd, Nicole J, Mauk, A. Grant, Andersen, Raymond J
Published in Journal of natural products (Washington, D.C.) (24.08.2012)
Published in Journal of natural products (Washington, D.C.) (24.08.2012)
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Abstract 1051: Dianhydrogalactitol (VAL-083) reduces glioblastoma tumor growth upon bevacizumab-induced hypoxia, in vivo
Golebiewska, Anna, Oudin, Anais, Steino, Anne, Niclou, Simone P., Bacha, Jeffrey, Brown, Dennis M.
Published in Cancer research (Chicago, Ill.) (01.07.2019)
Published in Cancer research (Chicago, Ill.) (01.07.2019)
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Abstract 3499: Dianhydrogalactitol (VAL-083) in combination with AZD1775 increases survival in diffuse intrinsic pontine glioma (DIPG), in vivo
Steino, Anne, Yang, Xiaodong, Kline, Cassie, Bacha, Jeffrey, Brown, Dennis M., Mueller, Sabine
Published in Cancer research (Chicago, Ill.) (01.07.2019)
Published in Cancer research (Chicago, Ill.) (01.07.2019)
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Abstract 2985: Molecular mechanisms of dianhydrogalactitol (VAL-083) in cancer treatment
Zhai, Beibei, Steino, Anne, Bacha, Jeffrey, Brown, Dennis, Daugaard, Mads
Published in Cancer research (Chicago, Ill.) (15.07.2016)
Published in Cancer research (Chicago, Ill.) (15.07.2016)
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Abstract B30: Dianhydrogalactitol (VAL-083) has the potential to overcome major challenges in the treatment of DIPG
Steino, Anne, Zhai, Beibei, Zhai, Beibei, Bacha, Jeffrey, Brown, Dennis, Fouse, Shaun, Costello, Joe, Daugaard, Mads, Daugaard, Mads, Mueller, Sabine
Published in Cancer research (Chicago, Ill.) (01.10.2018)
Published in Cancer research (Chicago, Ill.) (01.10.2018)
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Proteomic Screens for Suppressors of Anoikis Identify IL1RAP as a Promising Surface Target in Ewing Sarcoma
Zhang, Hai-Feng, Hughes, Christopher S, Li, Wei, He, Jian-Zhong, Surdez, Didier, El-Naggar, Amal M, Cheng, Hongwei, Prudova, Anna, Delaidelli, Alberto, Negri, Gian Luca, Li, Xiaojun, Ørum-Madsen, Maj Sofie, Lizardo, Michael M, Oo, Htoo Zarni, Colborne, Shane, Shyp, Taras, Scopim-Ribeiro, Renata, Hammond, Colin A, Dhez, Anne-Chloe, Langman, Sofya, Lim, Jonathan K M, Kung, Sonia H Y, Li, Amy, Steino, Anne, Daugaard, Mads, Parker, Seth J, Geltink, Ramon I Klein, Orentas, Rimas J, Xu, Li-Yan, Morin, Gregg B, Delattre, Olivier, Dimitrov, Dimiter S, Sorensen, Poul H
Published in Cancer discovery (01.11.2021)
Published in Cancer discovery (01.11.2021)
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