Synthesis of pyrazoles and isoxazoles as potent αvβ3 receptor antagonists
PENNING, Thomas D, KHILEVICH, Albert, HANNEKE, Melanie L, KEENE, Jeffery L, KLOVER, Jon A, NICKOLS, G. Allen, NICKOLS, Maureen A, RADER, Randall K, SETTLE, Steven L, SHANNON, Kristen E, STEININGER, Christina N, WESTLIN, Marisa M, CHEN, Barbara B, WESTLIN, William F, RUSSELL, Mark A, BOYS, Mark L, YAPING WANG, DUFFIN, Tiffany, ENGLEMAN, V. Wayne, FINN, Mary Beth, FREEMAN, Sandra K
Published in Bioorganic & medicinal chemistry letters (15.06.2006)
Published in Bioorganic & medicinal chemistry letters (15.06.2006)
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Convergent, parallel synthesis of a series of β-substituted 1,2,4-oxadiazole butanoic acids as potent and selective αvβ3 receptor antagonists
BOYS, Mark L, SCHRETZMAN, Lori A, STENMARK, Heather G, HONGWEI WU, SPANGLER, Dale P, CLARE, Michael, DESAI, Bipin N, KHANNA, Ish K, NGUYEN, Maria N, DUFFIN, Tiffany, WAYNE ENGLEMAN, V, FINN, Mary Beth, CHANDRAKUMAR, Nizal S, FREEMAN, Sandra K, HANNEKE, Melanie L, KEENE, Jeffery L, KLOVER, Jon A, NICKOLS, G. Allen, NICKOLS, Maureen A, STEININGER, Christina N, WESTLIN, Marisa, WESTLIN, William, YU, Yi X, TOLLEFSON, Michael B, YAPING WANG, DALTON, Christopher R, NORRING, Sarah A, MOHLER, Scott B, DOWNS, Victoria L, PENNING, Thomas D, RUSSELL, Mark A, WENDT, John A, CHEN, Barbara B
Published in Bioorganic & medicinal chemistry letters (15.02.2006)
Published in Bioorganic & medicinal chemistry letters (15.02.2006)
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Journal Article
Synthesis of 2,5-thiazole butanoic acids as potent and selective αvβ3 integrin receptor antagonists with improved oral pharmacokinetic properties
WENDT, John A, HONGWEI WU, KEENE, Jeffery L, WAYNE ENGLEMAN, V, FREEMAN, Sandra K, HANNEKE, Melanie L, SHANNON, Kristen E, NICKOLS, Maureen A, STEININGER, Christina N, WESTLIN, Marissa, KLOVER, Jon A, WESTLIN, William, STENMARK, Heather G, NICKOLS, G. Allen, RUSSELL, Mark A, BOYS, Mark L, DOWNS, Victoria L, PENNING, Thomas D, CHEN, Barbara B, YAPING WANG, DUFFIN, Tiffany, FINN, Mary Beth
Published in Bioorganic & medicinal chemistry letters (15.02.2006)
Published in Bioorganic & medicinal chemistry letters (15.02.2006)
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Journal Article
Synthesis of pyrazoles and isoxazoles as potent alpha(v)beta3 receptor antagonists
Penning, Thomas D, Khilevich, Albert, Chen, Barbara B, Russell, Mark A, Boys, Mark L, Wang, Yaping, Duffin, Tiffany, Engleman, V Wayne, Finn, Mary Beth, Freeman, Sandra K, Hanneke, Melanie L, Keene, Jeffery L, Klover, Jon A, Nickols, G Allen, Nickols, Maureen A, Rader, Randall K, Settle, Steven L, Shannon, Kristen E, Steininger, Christina N, Westlin, Marisa M, Westlin, William F
Published in Bioorganic & medicinal chemistry letters (15.06.2006)
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Published in Bioorganic & medicinal chemistry letters (15.06.2006)
Journal Article
Synthesis of pyrazoles and isoxazoles as potent alpha sub(v) beta sub(3) receptor antagonists
Penning, Thomas D, Khilevich, Albert, Chen, Barbara B, Russell, Mark A, Boys, Mark L, Wang, Yaping, Duffin, Tiffany, Engleman, VWayne, Finn, Mary Beth, Freeman, Sandra K, Hanneke, Melanie L, Keene, Jeffery L, Klover, Jon A, Nickols, GAllen, Nickols, Maureen A, Rader, Randall K, Settle, Steven L, Shannon, Kristen E, Steininger, Christina N, Westlin, Marisa M, Westlin, William F
Published in Bioorganic & medicinal chemistry letters (01.06.2006)
Published in Bioorganic & medicinal chemistry letters (01.06.2006)
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Journal Article
Synthesis of 2,5-thiazole butanoic acids as potent and selective alpha(v)beta3 integrin receptor antagonists with improved oral pharmacokinetic properties
Wendt, John A, Wu, Hongwei, Stenmark, Heather G, Boys, Mark L, Downs, Victoria L, Penning, Thomas D, Chen, Barbara B, Wang, Yaping, Duffin, Tiffany, Finn, Mary Beth, Keene, Jeffery L, Engleman, V Wayne, Freeman, Sandra K, Hanneke, Melanie L, Shannon, Kristen E, Nickols, Maureen A, Steininger, Christina N, Westlin, Marissa, Klover, Jon A, Westlin, William, Nickols, G Allen, Russell, Mark A
Published in Bioorganic & medicinal chemistry letters (15.02.2006)
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Published in Bioorganic & medicinal chemistry letters (15.02.2006)
Journal Article
Synthesis of 2,5-thiazole butanoic acids as potent and selective alpha sub(v) beta sub(3) integrin receptor antagonists with improved oral pharmacokinetic properties
Wendt, John A, Wu, Hongwei, Stenmark, Heather G, Boys, Mark L, Downs, Victoria L, Penning, Thomas D, Chen, Barbara B, Wang, Yaping, Duffin, Tiffany, Finn, Mary Beth, Keene, Jeffery L, Engleman, VWayne, Freeman, Sandra K, Hanneke, Melanie L, Shannon, Kristen E, Nickols, Maureen A, Steininger, Christina N, Westlin, Marissa, Klover, Jon A, Westlin, William, Nickols, GAllen, Russell, Mark A
Published in Bioorganic & medicinal chemistry letters (01.02.2006)
Published in Bioorganic & medicinal chemistry letters (01.02.2006)
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Journal Article
Synthesis of 2,5-thiazole butanoic acids as potent and selective α vβ 3 integrin receptor antagonists with improved oral pharmacokinetic properties
Wendt, John A., Wu, Hongwei, Stenmark, Heather G., Boys, Mark L., Downs, Victoria L., Penning, Thomas D., Chen, Barbara B., Wang, Yaping, Duffin, Tiffany, Finn, Mary Beth, Keene, Jeffery L., Engleman, V. Wayne, Freeman, Sandra K., Hanneke, Melanie L., Shannon, Kristen E., Nickols, Maureen A., Steininger, Christina N., Westlin, Marissa, Klover, Jon A., Westlin, William, Nickols, G. Allen, Russell, Mark A.
Published in Bioorganic & medicinal chemistry letters (2006)
Published in Bioorganic & medicinal chemistry letters (2006)
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Journal Article
Synthesis of pyrazoles and isoxazoles as potent α vβ 3 receptor antagonists
Penning, Thomas D., Khilevich, Albert, Chen, Barbara B., Russell, Mark A., Boys, Mark L., Wang, Yaping, Duffin, Tiffany, Engleman, V. Wayne, Finn, Mary Beth, Freeman, Sandra K., Hanneke, Melanie L., Keene, Jeffery L., Klover, Jon A., Nickols, G. Allen, Nickols, Maureen A., Rader, Randall K., Settle, Steven L., Shannon, Kristen E., Steininger, Christina N., Westlin, Marisa M., Westlin, William F.
Published in Bioorganic & medicinal chemistry letters (2006)
Published in Bioorganic & medicinal chemistry letters (2006)
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Journal Article
Convergent, parallel synthesis of a series of beta-substituted 1,2,4-oxadiazole butanoic acids as potent and selective alpha(v)beta3 receptor antagonists
Boys, Mark L, Schretzman, Lori A, Chandrakumar, Nizal S, Tollefson, Michael B, Mohler, Scott B, Downs, Victoria L, Penning, Thomas D, Russell, Mark A, Wendt, John A, Chen, Barbara B, Stenmark, Heather G, Wu, Hongwei, Spangler, Dale P, Clare, Michael, Desai, Bipin N, Khanna, Ish K, Nguyen, Maria N, Duffin, Tiffany, Engleman, V Wayne, Finn, Mary Beth, Freeman, Sandra K, Hanneke, Melanie L, Keene, Jeffery L, Klover, Jon A, Nickols, G Allen, Nickols, Maureen A, Steininger, Christina N, Westlin, Marisa, Westlin, William, Yu, Yi X, Wang, Yaping, Dalton, Christopher R, Norring, Sarah A
Published in Bioorganic & medicinal chemistry letters (15.02.2006)
Get full text
Published in Bioorganic & medicinal chemistry letters (15.02.2006)
Journal Article
Convergent, parallel synthesis of a series of beta -substituted 1,2,4- oxadiazole butanoic acids as potent and selective alpha sub(v) beta sub(3) receptor antagonists
Boys, Mark L, Schretzman, Lori A, Chandrakumar, Nizal S, Tollefson, Michael B, Mohler, Scott B, Downs, Victoria L, Penning, Thomas D, Russell, Mark A, Wendt, John A, Chen, Barbara B, Stenmark, Heather G, Wu, Hongwei, Spangler, Dale P, Clare, Michael, Desai, Bipin N, Khanna, Ish K, Nguyen, Maria N, Duffin, Tiffany, Engleman, VWayne, Finn, Mary Beth, Freeman, Sandra K, Hanneke, Melanie L, Keene, Jeffery L, Klover, Jon A, Nickols, GAllen, Nickols, Maureen A, Steininger, Christina N, Westlin, Marisa, Westlin, William, Yu, Yi X, Wang, Yaping, Dalton, Christopher R, Norring, Sarah A
Published in Bioorganic & medicinal chemistry letters (01.02.2006)
Published in Bioorganic & medicinal chemistry letters (01.02.2006)
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Journal Article
Convergent, parallel synthesis of a series of β-substituted 1,2,4-oxadiazole butanoic acids as potent and selective α vβ 3 receptor antagonists
Boys, Mark L., Schretzman, Lori A., Chandrakumar, Nizal S., Tollefson, Michael B., Mohler, Scott B., Downs, Victoria L., Penning, Thomas D., Russell, Mark A., Wendt, John A., Chen, Barbara B., Stenmark, Heather G., Wu, Hongwei, Spangler, Dale P., Clare, Michael, Desai, Bipin N., Khanna, Ish K., Nguyen, Maria N., Duffin, Tiffany, Engleman, V. Wayne, Finn, Mary Beth, Freeman, Sandra K., Hanneke, Melanie L., Keene, Jeffery L., Klover, Jon A., Nickols, G. Allen, Nickols, Maureen A., Steininger, Christina N., Westlin, Marisa, Westlin, William, Yu, Yi X., Wang, Yaping, Dalton, Christopher R., Norring, Sarah A.
Published in Bioorganic & medicinal chemistry letters (2006)
Published in Bioorganic & medicinal chemistry letters (2006)
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The glycoprotease of Pasteurella haemolytica A1 eliminates binding of myeloid cells to P-selectin but not to E-selectin
Steininger, Christina N., Eddy, Christopher A., Leimgruber, Richard M., Mellors, Alan, Welply, Joseph K.
Published in Biochemical and biophysical research communications (30.10.1992)
Published in Biochemical and biophysical research communications (30.10.1992)
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A peptide isolated by phage display binds to ICAM-1 and inhibits binding to LFA-1
Welply, Joseph K., Steininger, Christina N., Caparon, Maire, Michener, Marshall L., Howard, Susan C., Pegg, Lyle E., Meyer, Debra M., De Ciechi, Pamela A., Devine, Catherine S., Casperson, Gerald F.
Published in Proteins, structure, function, and bioinformatics (01.11.1996)
Published in Proteins, structure, function, and bioinformatics (01.11.1996)
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Intratracheal administration of endotoxin and cytokines: VIII. LPS induces E-selectin expression; anti-E-selectin and soluble E-selectin inhibit acute inflammation
Ulich, T R, Howard, S C, Remick, D G, Yi, E S, Collins, T, Guo, K, Yin, S, Keene, J L, Schmuke, J J, Steininger, C N
Published in Inflammation (01.08.1994)
Published in Inflammation (01.08.1994)
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