Discovery of Nivasorexant (ACT-539313): The First Selective Orexin‑1 Receptor Antagonist (SO1RA) Investigated in Clinical Trials
Williams, Jodi T., Bolli, Martin H., Brotschi, Christine, Sifferlen, Thierry, Steiner, Michel A., Treiber, Alexander, Gatfield, John, Boss, Christoph
Published in Journal of medicinal chemistry (22.02.2024)
Published in Journal of medicinal chemistry (22.02.2024)
Get full text
Journal Article
Role of the endocannabinoid system in regulation of the hypothalamic-pituitary-adrenocortical axis
Get full text
Book Chapter
Journal Article
Discovery and Characterization of ACT-335827, an Orally Available, Brain Penetrant Orexin Receptor Type1 Selective Antagonist
Steiner, Michel A., Gatfield, John, Brisbare-Roch, Catherine, Dietrich, Hendrik, Treiber, Alexander, Jenck, Francois, Boss, Christoph
Published in ChemMedChem (01.06.2013)
Published in ChemMedChem (01.06.2013)
Get full text
Journal Article
ΔFosB in brain reward circuits mediates resilience to stress and antidepressant responses
LaPlant, Quincey C, Watts, Emily L, Dietz, David M, Vialou, Vincent, Ohnishi, Yoko H, Wallace, Deanna L, Steiner, Michel A, Tamminga, Carol A, Ohnishi, Yoshinori N, Mouzon, Ezekiell, Warren, Brandon L, Bolaños, Carlos A, Nestler, Eric J, Neve, Rachael L, Rush, Augustus J, Iñiguez, Sergio D, Ghose, Subroto, Krishnan, Vaishnav, Robison, Alfred J, Covington, Herbert E, Berton, Olivier
Published in Nature neuroscience (01.06.2010)
Published in Nature neuroscience (01.06.2010)
Get full text
Journal Article
Antidepressant-like behavioral effects of impaired cannabinoid receptor type 1 signaling coincide with exaggerated corticosterone secretion in mice
Steiner, Michel A, Marsicano, Giovanni, Nestler, Eric J, Holsboer, Florian, Lutz, Beat, Wotjak, Carsten T
Published in Psychoneuroendocrinology (01.01.2008)
Published in Psychoneuroendocrinology (01.01.2008)
Get full text
Journal Article
Requirement of Cannabinoid Receptor Type 1 for the Basal Modulation of Hypothalamic-Pituitary-Adrenal Axis Function
Cota, Daniela, Steiner, Michel-Alexander, Marsicano, Giovanni, Cervino, Cristina, Herman, James P, Grübler, Yvonne, Stalla, Johanna, Pasquali, Renato, Lutz, Beat, Stalla, Günter K, Pagotto, Uberto
Published in Endocrinology (Philadelphia) (01.04.2007)
Published in Endocrinology (Philadelphia) (01.04.2007)
Get full text
Journal Article
Differential effects of the dual orexin receptor antagonist almorexant and the GABA(A)-α1 receptor modulator zolpidem, alone or combined with ethanol, on motor performance in the rat
Steiner, Michel A, Lecourt, Hugues, Strasser, Daniel S, Brisbare-Roch, Catherine, Jenck, François
Published in Neuropsychopharmacology (New York, N.Y.) (01.03.2011)
Published in Neuropsychopharmacology (New York, N.Y.) (01.03.2011)
Get full text
Journal Article
Structure-Activity Relationship, Biological, and Pharmacological Characterization of the Proline Sulfonamide ACT-462206: a Potent, Brain-Penetrant Dual Orexin 1/Orexin 2 Receptor Antagonist
Boss, Christoph, Roch-Brisbare, Catherine, Steiner, Michel A., Treiber, Alexander, Dietrich, Hendrik, Jenck, Francois, von Raumer, Markus, Sifferlen, Thierry, Brotschi, Christine, Heidmann, Bibia, Williams, Jodi T., Aissaoui, Hamed, Siegrist, Romain, Gatfield, John
Published in ChemMedChem (01.11.2014)
Published in ChemMedChem (01.11.2014)
Get full text
Journal Article
Examining the role of endogenous orexins in hypothalamus–pituitary–adrenal axis endocrine function using transient dual orexin receptor antagonism in the rat
Steiner, Michel A, Sciarretta, Carla, Brisbare-Roch, Catherine, Strasser, Daniel S, Studer, Rolf, Jenck, Francois
Published in Psychoneuroendocrinology (01.04.2013)
Published in Psychoneuroendocrinology (01.04.2013)
Get full text
Journal Article
Plasma neurofilament light, glial fibrillary acidic protein and lysosphingolipid biomarkers for pharmacodynamics and disease monitoring of GM2 and GM1 gangliosidoses patients
Welford, Richard W.D., Farine, Herve, Steiner, Michel, Garzotti, Marco, Dobrenis, Kostantin, Sievers, Claudia, Strasser, Daniel S., Amraoui, Yasmina, Groenen, Peter M.A., Giugliani, Roberto, Mengel, Eugen
Published in Molecular genetics and metabolism reports (01.03.2022)
Published in Molecular genetics and metabolism reports (01.03.2022)
Get full text
Journal Article