Involvement of β-site APP cleaving enzyme 1 (BACE1) in amyloid precursor protein-mediated enhancement of memory and activity-dependent synaptic plasticity
Ma, Huifang, Lesné, Sylvain, Kotilinek, Linda, Steidl-Nichols, Jill V, Sherman, Mathew, Younkin, Linda, Younkin, Steven, Forster, Colleen, Sergeant, Nicolas, Delacourte, André, Vassar, Robert, Citron, Martin, Kofuji, Paulo, Boland, Linda M, Ashe, Karen H
Published in Proceedings of the National Academy of Sciences - PNAS (08.05.2007)
Published in Proceedings of the National Academy of Sciences - PNAS (08.05.2007)
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From the Cover: Evaluation of the Effects of Tanezumab, a Monoclonal Antibody Against Nerve Growth Factor, on the Sympathetic Nervous System in Adult Cynomolgus Monkeys (Macaca fascicularis): A Stereologic, Histomorphologic, and Cardiofunctional Assessment
Belanger, Patrice, Butler, Paul, Butt, Mark, Bhatt, Siddhartha, Foote, Stephen, Shelton, David, Evans, Mark, Arends, Rosalinda, Hurst, Susan, Okerberg, Carlin, Cummings, Thomas, Potter, David, Steidl-Nichols, Jill, Zorbas, Mark
Published in Toxicological sciences (01.08.2017)
Published in Toxicological sciences (01.08.2017)
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General Principles for the Validation of Proarrhythmia Risk Prediction Models: An Extension of the CiPA In Silico Strategy
Li, Zhihua, Mirams, Gary R., Yoshinaga, Takashi, Ridder, Bradley J., Han, Xiaomei, Chen, Janell E., Stockbridge, Norman L., Wisialowski, Todd A., Damiano, Bruce, Severi, Stefano, Morissette, Pierre, Kowey, Peter R., Holbrook, Mark, Smith, Godfrey, Rasmusson, Randall L., Liu, Michael, Song, Zhen, Qu, Zhilin, Leishman, Derek J., Steidl‐Nichols, Jill, Rodriguez, Blanca, Bueno‐Orovio, Alfonso, Zhou, Xin, Passini, Elisa, Edwards, Andrew G., Morotti, Stefano, Ni, Haibo, Grandi, Eleonora, Clancy, Colleen E., Vandenberg, Jamie, Hill, Adam, Nakamura, Mikiko, Singer, Thomas, Polonchuk, Liudmila, Greiter‐Wilke, Andrea, Wang, Ken, Nave, Stephane, Fullerton, Aaron, Sobie, Eric A., Paci, Michelangelo, Musuamba Tshinanu, Flora, Strauss, David G.
Published in Clinical pharmacology and therapeutics (01.01.2020)
Published in Clinical pharmacology and therapeutics (01.01.2020)
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Altered short-term hippocampal synaptic plasticity in mutant alpha-synuclein transgenic mice
Steidl, Jill V, Gomez-Isla, Teresa, Mariash, Ami, Ashe, Karen Hsiao, Boland, Linda M
Published in Neuroreport (10.02.2003)
Published in Neuroreport (10.02.2003)
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Validation and utility of the PhysioTel™ Digital M11 telemetry implant for cardiovascular data evaluation in cynomolgus monkeys and Beagle dogs
Cordes, Jason S., Heyen, Jonathan R., Volberg, Marlo L., Poy, Nancy, Kreuser, Steven, Shoieb, Ahmed M., Steidl-Nichols, Jill
Published in Journal of pharmacological and toxicological methods (01.05.2016)
Published in Journal of pharmacological and toxicological methods (01.05.2016)
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Fluorescently Labeled Analogues of Dofetilide as High-Affinity Fluorescence Polarization Ligands for the Human Ether-a-go-go-Related Gene (hERG) Channel
Singleton, David H, Boyd, Helen, Steidl-Nichols, Jill V, Deacon, Matt, de Groot, Marcel J, Price, David, Nettleton, David O, Wallace, Nora K, Troutman, Matthew D, Williams, Christine, Boyd, James G
Published in Journal of medicinal chemistry (28.06.2007)
Published in Journal of medicinal chemistry (28.06.2007)
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Early evaluation of compound QT prolongation effects: A predictive 384-well fluorescence polarization binding assay for measuring hERG blockade
Deacon, Matt, Singleton, David, Szalkai, Nikki, Pasieczny, Rodger, Peacock, Chris, Price, David, Boyd, James, Boyd, Helen, Steidl-Nichols, Jill V., Williams, Christine
Published in Journal of pharmacological and toxicological methods (2007)
Published in Journal of pharmacological and toxicological methods (2007)
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Impact of study design on proarrhythmia prediction in the SCREENIT rabbit isolated heart model
Steidl-Nichols, Jill V., Hanton, Gilles, Leaney, Joanne, Liu, Ruei-Che, Leishman, Derek, McHarg, Aileen, Wallis, Rob
Published in Journal of pharmacological and toxicological methods (2008)
Published in Journal of pharmacological and toxicological methods (2008)
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P4‐193: The nonclinical safety profile of the 5‐HT4 partial agonist, PF‐04995274, supported clinical development for symptomatic treatment of Alzheimer's disease
Pettersen, Betty, Harris, Peter, Steidl, Jill, Marcek, John, Mirsky, Michael, Pardo, Ingrid, Papanikolaou, Alexandros
Published in Alzheimer's & dementia (01.07.2011)
Published in Alzheimer's & dementia (01.07.2011)
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The nonclinical safety profile of the 5-HT4 partial agonist, PF-04995274, supported clinical development for symptomatic treatment of Alzheimer's disease
Pettersen, Betty, Harris, Peter, Steidl, Jill, Marcek, John, Mirsky, Michael, Pardo, Ingrid, Papanikolaou, Alexandros
Published in Alzheimer's & dementia (01.07.2011)
Published in Alzheimer's & dementia (01.07.2011)
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Cross species PKPD modeling of moxifloxacin effects on cardiac repolarization
Gorczyca, William, Wolfgang, Eric, Watson, Kenny, Wolford, David, Zhang, Ying, Steidl, Jill, Koup, Jeff, Wisialowski, Todd
Published in Journal of pharmacological and toxicological methods (01.07.2011)
Published in Journal of pharmacological and toxicological methods (01.07.2011)
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Validation of JET™ (Jacketed External Telemetry) technology for ECG and blood pressure assessment in the dog
Foote, Stephen C., Holloway, Jacob, Foote, Adrianne, Harris, Peter, Wolford, David, Li, Dingzhou, Wisialowski, Todd, Steidl, Jill
Published in Journal of pharmacological and toxicological methods (01.07.2011)
Published in Journal of pharmacological and toxicological methods (01.07.2011)
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Validation of combined toxicology and cardiovascular safety pharmacology studies using JET technology
Heyen, Jonathan R., May, Jeffrey R., Scott, Wesley, Palacio, Kimbie, Sacaan, Aida, Steidl, Jill, Foote, Steve, Poy, Nancy, Volberg, Marlo, McHarg, Aileen D.
Published in Journal of pharmacological and toxicological methods (01.07.2011)
Published in Journal of pharmacological and toxicological methods (01.07.2011)
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Effects of milrinone on myocardial contractility across different species
Ringer, Laura W., Austin-LaFrance, Robert, Gorczyca, William P., Wolfgang, Eric A., Wisialowski, Todd A., Steidl, Jill
Published in Journal of pharmacological and toxicological methods (01.07.2011)
Published in Journal of pharmacological and toxicological methods (01.07.2011)
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Assessment of Cardiac Troponin I Responses in Nonhuman Primates during Restraint, Blood Collection, and Dosing in Preclinical Safety Studies
Reagan, William J, Barnes, Robert, Harris, Peter, Summers, Sandy, Lopes, Sarah, Stubbs, Makeida, Blackwell, David, Steidl-Nichols, Jill
Published in Toxicologic pathology (01.02.2017)
Published in Toxicologic pathology (01.02.2017)
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Statistical power analysis of cardiovascular safety pharmacology studies in conscious rats
Bhatt, Siddhartha, Li, Dingzhou, Flynn, Declan, Wisialowski, Todd, Hemkens, Michelle, Steidl-Nichols, Jill
Published in Journal of pharmacological and toxicological methods (01.09.2016)
Published in Journal of pharmacological and toxicological methods (01.09.2016)
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