Cell elasticity is regulated by the tropomyosin isoform composition of the actin cytoskeleton
Jalilian, Iman, Heu, Celine, Cheng, Hong, Freittag, Hannah, Desouza, Melissa, Stehn, Justine R, Bryce, Nicole S, Whan, Renee M, Hardeman, Edna C, Fath, Thomas, Schevzov, Galina, Gunning, Peter W
Published in PloS one (15.05.2015)
Published in PloS one (15.05.2015)
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Journal Article
MAPKAP Kinase-2 phosphorylation of PABPC1 controls its interaction with 14-3-3 proteins after DNA damage: A combined kinase and protein array approach
Stehn, Justine R, Floyd, Scott R, Wilker, Erik W, Reinhardt, H Christian, Clarke, Scott M, Huang, Qiuying, Polakiewicz, Roberto D, Sonenberg, Nahum, Kong, Yi Wen, Yaffe, Michael B
Published in Frontiers in molecular biosciences (06.04.2023)
Published in Frontiers in molecular biosciences (06.04.2023)
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Journal Article
New approaches to targeting the actin cytoskeleton for chemotherapy
Bonello, Teresa T, Stehn, Justine R, Gunning, Peter W
Published in Future medicinal chemistry (01.10.2009)
Published in Future medicinal chemistry (01.10.2009)
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Journal Article
A Novel Class of Anticancer Compounds Targets the Actin Cytoskeleton in Tumor Cells
STEHN, Justine R, HAASS, Nikolas K, FATH, Thomas, HILL, Timothy A, McCLUSKEY, Adam, SCHEVZOV, Galina, PALMER, Stephen J, HARDEMAN, Edna C, WINLAW, David, REEVE, Vivienne E, DIXON, Ian, WENINGER, Wolfgang, BONELLO MELISSA DESOUZA, Teresa, CRIPE, Timothy P, GUNNING, Peter W, KOTTYAN, Gregg, TREUTLEIN, Herbert, JUN ZENG, NASCIMENTO, Paula R. B. B, SEQUEIRA, Vanessa B, BUTLER, Tanya L, ALLANSON, Munif
Published in Cancer research (Chicago, Ill.) (15.08.2013)
Published in Cancer research (Chicago, Ill.) (15.08.2013)
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Journal Article
Tumor suppressor tropomyosin Tpm2.1 regulates sensitivity to apoptosis beyond anoikis characterized by changes in the levels of intrinsic apoptosis proteins
Desouza‐Armstrong, Melissa, Gunning, Peter W., Stehn, Justine R.
Published in Cytoskeleton (Hoboken, N.J.) (01.06.2017)
Published in Cytoskeleton (Hoboken, N.J.) (01.06.2017)
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Journal Article
Identification of Cancer-Targeted Tropomyosin Inhibitors and Their Synergy with Microtubule Drugs
Currier, Mark A, Stehn, Justine R, Swain, Ashleigh, Chen, Duo, Hook, Jeff, Eiffe, Eleanor, Heaton, Andrew, Brown, David, Nartker, Brooke A, Eaves, David W, Kloss, Nina, Treutlein, Herbert, Zeng, Jun, Alieva, Irina B, Dugina, Vera B, Hardeman, Edna C, Gunning, Peter W, Cripe, Timothy P
Published in Molecular cancer therapeutics (01.08.2017)
Published in Molecular cancer therapeutics (01.08.2017)
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Journal Article
Regulation of cell proliferation by ERK and signal-dependent nuclear translocation of ERK is dependent on Tm5NM1-containing actin filaments
Schevzov, Galina, Kee, Anthony J, Wang, Bin, Sequeira, Vanessa B, Hook, Jeff, Coombes, Jason D, Lucas, Christine A, Stehn, Justine R, Musgrove, Elizabeth A, Cretu, Alexandra, Assoian, Richard, Fath, Thomas, Hanoch, Tamar, Seger, Rony, Pleines, Irina, Kile, Benjamin T, Hardeman, Edna C, Gunning, Peter W
Published in Molecular biology of the cell (01.07.2015)
Published in Molecular biology of the cell (01.07.2015)
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Journal Article
Small molecule targeting of the actin associating protein tropomyosin Tpm3.1 increases neuroblastoma cell response to inhibition of Rac‐mediated multicellular invasion
Mitchell, Camilla B., Stehn, Justine R., O'Neill, Geraldine M.
Published in Cytoskeleton (Hoboken, N.J.) (01.07.2018)
Published in Cytoskeleton (Hoboken, N.J.) (01.07.2018)
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Journal Article
A small molecule inhibitor of tropomyosin dissociates actin binding from tropomyosin-directed regulation of actin dynamics
Bonello, Teresa T, Janco, Miro, Hook, Jeff, Byun, Alex, Appaduray, Mark, Dedova, Irina, Hitchcock-DeGregori, Sarah, Hardeman, Edna C, Stehn, Justine R, Böcking, Till, Gunning, Peter W
Published in Scientific reports (25.01.2016)
Published in Scientific reports (25.01.2016)
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Journal Article
On-target action of anti-tropomyosin drugs regulates glucose metabolism
Kee, Anthony J, Chagan, Jayshan, Chan, Jeng Yie, Bryce, Nicole S, Lucas, Christine A, Zeng, Jun, Hook, Jeff, Treutlein, Herbert, Laybutt, D Ross, Stehn, Justine R, Gunning, Peter W, Hardeman, Edna C
Published in Scientific reports (15.03.2018)
Published in Scientific reports (15.03.2018)
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Journal Article
Cover Image, Volume 74, Issue 6
Desouza‐Armstrong, Melissa, Gunning, Peter W., Stehn, Justine R.
Published in Cytoskeleton (Hoboken, N.J.) (01.06.2017)
Published in Cytoskeleton (Hoboken, N.J.) (01.06.2017)
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Journal Article
Cover Image, Volume 74, Issue 6
Desouza‐Armstrong, Melissa, Gunning, Peter W., Stehn, Justine R.
Published in Cytoskeleton (Hoboken, N.J.) (01.06.2017)
Published in Cytoskeleton (Hoboken, N.J.) (01.06.2017)
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Journal Article
Hypoxia alters the recruitment of tropomyosins into the actin stress fibres of neuroblastoma cells
Glass, Joshua J, Phillips, Phoebe A, Gunning, Peter W, Stehn, Justine R
Published in BMC cancer (16.10.2015)
Published in BMC cancer (16.10.2015)
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Journal Article
High-Content Imaging of Unbiased Chemical Perturbations Reveals that the Phenotypic Plasticity of the Actin Cytoskeleton Is Constrained
Bryce, Nicole S., Failes, Tim W., Stehn, Justine R., Baker, Karen, Zahler, Stefan, Arzhaeva, Yulia, Bischof, Leanne, Lyons, Ciaran, Dedova, Irina, Arndt, Greg M., Gaus, Katharina, Goult, Benjamin T., Hardeman, Edna C., Gunning, Peter W., Lock, John G.
Published in Cell systems (27.11.2019)
Published in Cell systems (27.11.2019)
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Journal Article
Phosphorylation of nonmuscle myosin heavy chain IIA on Ser1917 is mediated by protein kinase C beta II and coincides with the onset of stimulated degranulation of RBL-2H3 mast cells
Ludowyke, Russell I, Elgundi, Zehra, Kranenburg, Tanya, Stehn, Justine R, Schmitz-Peiffer, Carsten, Hughes, William E, Biden, Trevor J
Published in The Journal of immunology (1950) (01.08.2006)
Published in The Journal of immunology (1950) (01.08.2006)
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Journal Article
Abstract C208: Targeting the actin cytoskeleton of neuroblastoma: Elucidating the mechanism by which a novel class of anti-cancer compounds induces tumor cell death
Desouza, Melissa, Nguyen, Margaret, Gunning, Peter W., Stehn, Justine R.
Published in Molecular cancer therapeutics (01.11.2013)
Published in Molecular cancer therapeutics (01.11.2013)
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Journal Article
Abstract B50: Synergistic anti-neuroblastoma efficacy using combinatorial cytoskeletal inhibitors
Stehn, Justine R., Chen, Duo, Currier, Mark A., Eaves, David, Desouza, Melissa, Moosavian, Matthew, Cripe, Timothy P., Gunning, Peter W.
Published in Cancer research (Chicago, Ill.) (15.10.2014)
Published in Cancer research (Chicago, Ill.) (15.10.2014)
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