Genetic Silencing of AKT Induces Melanoma Cell Death via mTOR Suppression
Parkman, Gennie L, Turapov, Tursun, Kircher, David A, Burnett, William J, Stehn, Christopher M, O'Toole, Kayla, Culver, Katie M, Chadwick, Ashley T, Elmer, Riley C, Flaherty, Ryan, Stanley, Karly A, Foth, Mona, Lum, David H, Judson-Torres, Robert L, Friend, John E, VanBrocklin, Matthew W, McMahon, Martin, Holmen, Sheri L
Published in Molecular cancer therapeutics (04.03.2024)
Published in Molecular cancer therapeutics (04.03.2024)
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Journal Article
AKT1E17K Activates Focal Adhesion Kinase and Promotes Melanoma Brain Metastasis
Kircher, David A., Trombetti, Kirby A., Silvis, Mark R., Parkman, Gennie L., Fischer, Grant M., Angel, Stephanie N., Stehn, Christopher M., Strain, Sean C., Grossmann, Allie H., Duffy, Keith L., Boucher, Kenneth M., McMahon, Martin, Davies, Michael A., Mendoza, Michelle C., VanBrocklin, Matthew W., Holmen, Sheri L.
Published in Molecular cancer research (01.09.2019)
Published in Molecular cancer research (01.09.2019)
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Journal Article
Transposon Mutagenesis Reveals RBMS3 Silencing as a Promoter of Malignant Progression of BRAFV600E-Driven Lung Tumorigenesis
Vaishnavi, Aria, Juan, Joseph, Jacob, Maebh, Stehn, Christopher, Gardner, Eric E, Scherzer, Michael T, Schuman, Sophia, Van Veen, J Edward, Murphy, Brandon, Hackett, Christopher S, Dupuy, Adam J, Chmura, Steven A, van der Weyden, Louise, Newberg, Justin Y, Liu, Annie, Mann, Karen, Rust, Alistair G, Weiss, William A, Kinsey, Conan G, Adams, David J, Grossmann, Allie, Mann, Michael B, McMahon, Martin
Published in Cancer research (Chicago, Ill.) (15.11.2022)
Published in Cancer research (Chicago, Ill.) (15.11.2022)
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Journal Article
Abstract 6011: Methylation profiling reveals the role of PRC2 in regulating DNA methylome changes in malignant peripheral nerve sheath tumors
Stehn, Christopher M., Bhunia, Minu, Williams, Kyle B., Larsson, Alex T., Largaespada, David A.
Published in Cancer research (Chicago, Ill.) (04.04.2023)
Published in Cancer research (Chicago, Ill.) (04.04.2023)
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Abstract B009: Characterizing the super enhancer landscape of H3K27me3 loss in MPNST and DIPG
Stehn, Christopher M., Bhunia, Minu, Williams, Kyle, Larsson, Alex T., Caride, Ariel, Lee, Jeong-Heon, Ordog, Tamas, Largaespada, David
Published in Cancer research (Chicago, Ill.) (04.03.2024)
Published in Cancer research (Chicago, Ill.) (04.03.2024)
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Abstract A010: Methylation profiling reveals the role of PRC2 in regulating DNA methylome stochasticity in malignant peripheral nerve sheath tumors
Stehn, Christopher M., Bhunia, Minu, Suppiah, Suganth, Herman, Adam, Zadeh, Gelareh, Largaespada, David
Published in Cancer research (Chicago, Ill.) (01.12.2022)
Published in Cancer research (Chicago, Ill.) (01.12.2022)
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Abstract A007: Integrative multiomic analysis reveals NOTCH signaling is derepressed by loss of PRC2 in malignant peripheral nerve sheath tumors
Bhunia, Minu, Stehn, Christopher M., Madala, Mahathi, Williams, Kyle, Larsson, Alex, Jubenville, Tyler, Suppiah, Suganth, Zadeh, Gelareh
Published in Cancer research (Chicago, Ill.) (01.12.2022)
Published in Cancer research (Chicago, Ill.) (01.12.2022)
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Abstract 2736: AKT1E17K activates focal adhesion kinase and promotes melanoma brain metastasis
Kircher, David A., Trombetti, Kirby A., Silvis, Mark R., Parkman, Gennie L., Fischer, Grant M., Angel, Stephanie N., Stehn, Christopher M., Strain, Sean C., Grossmann, Allie H., Duffy, Keith L., McMahon, Martin, Davies, Michael A., Mendoza, Michelle C., VanBrocklin, Matthew W., Holmen, Sheri L.
Published in Cancer research (Chicago, Ill.) (15.08.2020)
Published in Cancer research (Chicago, Ill.) (15.08.2020)
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Abstract 4127: Combined inhibition of RAF, MEK, and FAK attenuates melanoma brain metastases and prolongs survival in preclinical models
Stanley, Karly A., Almazan, Jared D., Turapov, Tursun, Kircher, David A., Parkman, Gennie L., Field, MiKaela N., Culver, Katie M., Stehn, Christopher M., Coma, Silvia, Pachter, Jonathan A., Colman, Howard, Holmen, Sheri L.
Published in Cancer research (Chicago, Ill.) (22.03.2024)
Published in Cancer research (Chicago, Ill.) (22.03.2024)
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Abstract 427: Newer generation mTOR inhibition represents effective therapeutic strategy for BRAF-mutant melanoma
Parkman, Gennie L., Turapov, Tursun, Kircher, David, Burnett, William, Stehn, Christopher, O'Toole, Kayla, Culver, Katie, Chadwick, Ashley, Elmer, Riley, Flaherty, Ryan, Foth, Mona, Stanley, Karly, Andtbacka, Robert, Lum, David, Judson-Torres, Robert, McMahon, Martin, Holmen, Sheri
Published in Cancer research (Chicago, Ill.) (04.04.2023)
Published in Cancer research (Chicago, Ill.) (04.04.2023)
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Journal Article
AKT1 E17K Activates Focal Adhesion Kinase and Promotes Melanoma Brain Metastasis
Kircher, David A, Trombetti, Kirby A, Silvis, Mark R, Parkman, Gennie L, Fischer, Grant M, Angel, Stephanie N, Stehn, Christopher M, Strain, Sean C, Grossmann, Allie H, Duffy, Keith L, Boucher, Kenneth M, McMahon, Martin, Davies, Michael A, Mendoza, Michelle C, VanBrocklin, Matthew W, Holmen, Sheri L
Published in Molecular cancer research (01.09.2019)
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Published in Molecular cancer research (01.09.2019)
Journal Article
"Transposon Mutagenesis Reveals RBMS3 as a Promoter of Malignant Progression of BRAFV600E-Driven Lung Tumorigenesis."
Vaishnavi, Aria, Joseph, Juan, Scherzer, Michael T, Vanveen, J Edward, Stehn, Christopher, Hackett, Christopher S, Dupuy, Adam, Chmura, Steven A, Van Der Weyden, Louise, Newberg, Justin Y, Mann, Karen M, Liu, Annie, Rust, Alistair G, Weiss, William A, Adams, David, Grossman, Allie, Mann, Michael B, Mcmahon, Martin
Published in bioRxiv (28.02.2022)
Published in bioRxiv (28.02.2022)
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