Search Results - "Stefan DENGL" :: K.UTB vyhledávací portál | TBU Library Retrieval Portal

Format chain exchange (FORCE) for high-throughput generation of bispecific antibodies in combinatorial binder-format matrices

Format chain exchange (FORCE) for high-throughput generation of bispecific antibodies in combinatorial binder-format matrices

by Dengl, Stefan, Mayer, Klaus, Bormann, Felix, Duerr, Harald, Hoffmann, Eike, Nussbaum, Bianca, Tischler, Michael, Wagner, Martina, Kuglstatter, Andreas, Leibrock, Lea, Buldun, Can, Georges, Guy, Brinkmann, Ulrich
Published in Nature communications (02.10.2020)

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Journal Article

Torpedo Nuclease Rat1 Is Insufficient to Terminate RNA Polymerase II in Vitro

Torpedo Nuclease Rat1 Is Insufficient to Terminate RNA Polymerase II in Vitro

by Dengl, Stefan, Cramer, Patrick
Published in The Journal of biological chemistry (07.08.2009)

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Oxidation in the complementarity-determining regions differentially influences the properties of therapeutic antibodies

Oxidation in the complementarity-determining regions differentially influences the properties of therapeutic antibodies

by Dashivets, Tetyana, Stracke, Jan, Dengl, Stefan, Knaupp, Alexander, Pollmann, Jan, Buchner, Johannes, Schlothauer, Tilman
Published in mAbs (16.11.2016)

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Journal Article

Aggregation and Chemical Modification of Monoclonal Antibodies under Upstream Processing Conditions

Aggregation and Chemical Modification of Monoclonal Antibodies under Upstream Processing Conditions

by Dengl, Stefan, Wehmer, Marc, Hesse, Friederike, Lipsmeier, Florian, Popp, Oliver, Lang, Kurt
Published in Pharmaceutical research (01.05.2013)

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Understanding the Half-Life Extension of Intravitreally Administered Antibodies Binding to Ocular Albumin

Understanding the Half-Life Extension of Intravitreally Administered Antibodies Binding to Ocular Albumin

by Hauri, Simon, Jakubiak, Paulina, Fueth, Matthias, Dengl, Stefan, Belli, Sara, Alvarez-Sánchez, Rubén, Caruso, Antonello
Published in Pharmaceutics (26.08.2020)

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Journal Article

Structure and in Vivo Requirement of the Yeast Spt6 SH2 Domain

Structure and in Vivo Requirement of the Yeast Spt6 SH2 Domain

by Dengl, Stefan, Mayer, Andreas, Sun, Mai, Cramer, Patrick
Published in Journal of molecular biology (29.05.2009)

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Journal Article

Allosteric antibody inhibition of human hepsin protease

Allosteric antibody inhibition of human hepsin protease

by Koschubs, Tobias, Dengl, Stefan, Dürr, Harald, Kaluza, Klaus, Georges, Guy, Hartl, Christiane, Jennewein, Stefan, Lanzendörfer, Martin, Auer, Johannes, Stern, Alvin, Huang, Kuo-Sen, Packman, Kathryn, Gubler, Ueli, Kostrewa, Dirk, Ries, Stefan, Hansen, Silke, Kohnert, Ulrich, Cramer, Patrick, Mundigl, Olaf
Published in Biochemical journal (15.03.2012)

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The Contorsbody, an antibody format for agonism: Design, structure, and function

The Contorsbody, an antibody format for agonism: Design, structure, and function

by Georges, Guy J., Dengl, Stefan, Bujotzek, Alexander, Hesse, Friederike, Fischer, Jens A.A., Gärtner, Achim, Benz, Jörg, Lauer, Matthias E., Ringler, Philippe, Stahlberg, Henning, Plath, Friederike, Brinkmann, Ulrich, Imhof-Jung, Sabine
Published in Computational and structural biotechnology journal (01.01.2020)

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Journal Article

Engineered hapten-binding antibody derivatives for modulation of pharmacokinetic properties of small molecules and targeted payload delivery

Engineered hapten-binding antibody derivatives for modulation of pharmacokinetic properties of small molecules and targeted payload delivery

by Dengl, Stefan, Sustmann, Claudio, Brinkmann, Ulrich
Published in Immunological reviews (01.03.2016)

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Journal Article

A Tandem SH2 Domain in Transcription Elongation Factor Spt6 Binds the Phosphorylated RNA Polymerase II C-terminal Repeat Domain (CTD)

A Tandem SH2 Domain in Transcription Elongation Factor Spt6 Binds the Phosphorylated RNA Polymerase II C-terminal Repeat Domain (CTD)

by Sun, Mai, Larivière, Laurent, Dengl, Stefan, Mayer, Andreas, Cramer, Patrick
Published in The Journal of biological chemistry (31.12.2010)

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Journal Article

Structural Basis of Transcription: Mismatch-Specific Fidelity Mechanisms and Paused RNA Polymerase II with Frayed RNA

Structural Basis of Transcription: Mismatch-Specific Fidelity Mechanisms and Paused RNA Polymerase II with Frayed RNA

by Sydow, Jasmin F., Brueckner, Florian, Cheung, Alan C.M., Damsma, Gerke E., Dengl, Stefan, Lehmann, Elisabeth, Vassylyev, Dmitry, Cramer, Patrick
Published in Molecular cell (26.06.2009)

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Journal Article

Interplay between reversible phosphorylation and irreversible ADP-ribosylation of eukaryotic translation elongation factor 2

Interplay between reversible phosphorylation and irreversible ADP-ribosylation of eukaryotic translation elongation factor 2

by Mateus-Seidl, Rita, Stahl, Sebastian, Dengl, Stefan, Birzele, Fabian, Herrmuth, Hedda, Mayer, Klaus, Niederfellner, Gerhard, Liu, Xiu-Fen, Pastan, Ira, Brinkmann, Ulrich
Published in Biological chemistry (26.03.2019)

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Journal Article

STABILIZED IMMUNOGLOBULIN DOMAINS

STABILIZED IMMUNOGLOBULIN DOMAINS

by STEFAN SEEBER, LAURENT LARIVIERE, LAURA CODARRI DEAK, EKKEHARD MOESSNER, ANNE-CLAIRE ZAGDOUN, JENS FISCHER, STEFAN DENGL, PABLO UMANA, THOMAS HOFER
Year of Publication 19.03.2024

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Patent

Abstract 2270: RG7769 (PD1-TIM3), a novel heterodimeric avidity-driven T cell specific PD-1/TIM-3 bispecific antibody lacking Fc-mediated effector functions for dual checkpoint inhibition to reactivate dysfunctional T cells

Abstract 2270: RG7769 (PD1-TIM3), a novel heterodimeric avidity-driven T cell specific PD-1/TIM-3 bispecific antibody lacking Fc-mediated effector functions for dual checkpoint inhibition to reactivate dysfunctional T cells

by Deak, Laura Laura Codarri, Seeber, Stefan, Perro, Mario, Weber, Patrick, Lauener, Laura, Chen, Standford, Offner, Sonja, Dengl, Stefan, Hesse, Friederike, Zwick, Adrian, Boettger, Marco, Bujotzek, Alexander, Benz, Jörg, Georges, Guy, Fertig, Georg, Lifke, Valeria, Fischer, Jens, Leclair, Stephane, Levitsky, Victor, Canamero, Marta, Lindner, Juha, Colombetti, Sara, Bendels, Stefanie, Boetsch, Christophe, Fueth, Matthias, Muecke, Merlind, Kao, Henry, Umana, Pablo, Klein, Christian
Published in Cancer research (Chicago, Ill.) (15.08.2020)

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Journal Article

MULTISPECIFIC ANTIBODIES AND USE THEREOF

MULTISPECIFIC ANTIBODIES AND USE THEREOF

by SEBASTIAN FENN, JOERG MOELLEKEN, GEORG TIEFENTHALER, STEFAN KLOSTERMANN, ALEXANDER BUJOTZEK, MEHER MAJETY, JENS FISCHER, CLAUDIA KIRSTENPFAD, SILKE KIRCHNER, STEFAN DENGL
Year of Publication 13.06.2023

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Patent

ANTI-TRANSFERRIN RECEPTOR ANTIBODIES WITH TAILORED AFFINITY

ANTI-TRANSFERRIN RECEPTOR ANTIBODIES WITH TAILORED AFFINITY

by JENS NIEWOEHNER, TILMAN SCHLOTHAUER, STEFAN DENGL, ULRICH GOEPFERT, GUY GEORGES
Year of Publication 25.06.2020

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Patent

ANTIBODY THAT BINDS TO VEGF AND IL-1BETA AND METHODS OF USE

ANTIBODY THAT BINDS TO VEGF AND IL-1BETA AND METHODS OF USE

by JOERG MOELLEKEN, JOERG BENZ, CHRISTIAN GASSNER, MUNDIGL OLAF, ROLAND BECKMANN, KRISTIAN HOBOLT JENSEN, PETER MICHAEL HUELSMANN, STEFAN DENGL, STEFAN LORENZ, KETTENBERGER HUBERT, SABINE IMHOF-JUNG, GUIDO HARTMANN
Year of Publication 08.11.2023

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Patent

Hapten‐directed spontaneous disulfide shuffling: a universal technology for site‐directed covalent coupling of payloads to antibodies

Hapten‐directed spontaneous disulfide shuffling: a universal technology for site‐directed covalent coupling of payloads to antibodies

by Dengl, Stefan, Hoffmann, Eike, Grote, Michael, Wagner, Cornelia, Mundigl, Olaf, Georges, Guy, Thorey, Irmgard, Stubenrauch, Kay‐Gunnar, Bujotzek, Alexander, Josel, Hans‐Peter, Dziadek, Sebastian, Benz, Joerg, Brinkmann, Ulrich
Published in The FASEB journal (01.05.2015)

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Journal Article

ANTI-ANG2 ANTIBODIES AND METHODS OF USE

ANTI-ANG2 ANTIBODIES AND METHODS OF USE

by JOERG MOELLEKEN, JOERG THOMAS REGULA, MICHAEL MOLHOJ, PETER MICHAEL HUELSMANN, STEFAN DENGL, KETTENBERGER HUBERT, GUY GEORGES
Year of Publication 01.04.2021

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Patent

PK modulation of haptenylated peptides via non-covalent antibody complexation

PK modulation of haptenylated peptides via non-covalent antibody complexation

by Hoffmann, Eike, Konkar, Anish, Dziadek, Sebastian, Josel, Hans-Peter, Conde-Knape, Karin, Kropp, Holger, Kling, Lothar, Stubenrauch, Kay, Thorey, Irmgard, Dengl, Stefan, Brinkmann, Ulrich
Published in Journal of controlled release (10.10.2013)

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