Discovery and Characterization of Novel, Potent, Non-Peptide Parathyroid Hormone-1 Receptor Antagonists
McDonald, Iain M, Austin, Carol, Buck, Ildiko M, Dunstone, David J, Gaffen, John, Griffin, Eric, Harper, Elaine A, Hull, Robert A. D, Kalindjian, S. Barret, Linney, Ian D, Low, Caroline M. R, Patel, Dipa, Pether, Michael J, Raynor, Michelle, Roberts, Sonia P, Shaxted, Mark E, Spencer, John, Steel, Katherine I. M, Sykes, David A, Wright, Paul T, Xun, Wei
Published in Journal of medicinal chemistry (04.10.2007)
Published in Journal of medicinal chemistry (04.10.2007)
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Journal Article
Optimization of 1,3,4-Benzotriazepine-Based CCK2 Antagonists to Obtain Potent, Orally Active Inhibitors of Gastrin-Mediated Gastric Acid Secretion
McDonald, Iain M, Black, James W, Buck, Ildiko M, Dunstone, David J, Griffin, Eric P, Harper, Elaine A, Hull, Robert A. D, Kalindjian, S. Barret, Lilley, Elliot J, Linney, Ian D, Pether, Michael J, Roberts, Sonia P, Shaxted, Mark E, Spencer, John, Steel, Katherine I. M, Sykes, David A, Walker, Martin K, Watt, Gillian F, Wright, Laurence, Wright, Paul T, Xun, Wei
Published in Journal of medicinal chemistry (28.06.2007)
Published in Journal of medicinal chemistry (28.06.2007)
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Journal Article
Optimization of the in Vitro and in Vivo Properties of a Novel Series of 2,4,5-Trisubstituted Imidazoles as Potent Cholecystokinin-2 (CCK2) Antagonists
Buck, Ildiko M, Black, James W, Cooke, Tracey, Dunstone, David J, Gaffen, John D, Griffin, Eric P, Harper, Elaine A, Hull, Robert A. D, Kalindjian, S. Barret, Lilley, Elliot J, Linney, Ian D, Low, Caroline M. R, McDonald, Iain M, Pether, Michael J, Roberts, Sonia P, Shankley, Nigel P, Shaxted, Mark E, Steel, Katherine I. M, Sykes, David A, Tozer, Matthew J, Watt, Gillian F, Walker, Martin K, Wright, Laurence, Wright, Paul T
Published in Journal of medicinal chemistry (03.11.2005)
Published in Journal of medicinal chemistry (03.11.2005)
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Journal Article
2,7-Dioxo-2,3,4,5,6,7-hexahydro-1H-benzo[h][1,4]diazonine as a New Template for the Design of CCK2 Receptor Antagonists
McDonald, Iain M, Dunstone, David J, Kalindjian, S. Barret, Linney, Ian D, Low, Caroline M. R, Pether, Michael J, Steel, Katherine I. M, Tozer, Matthew J, Vinter, J. G
Published in Journal of medicinal chemistry (21.09.2000)
Published in Journal of medicinal chemistry (21.09.2000)
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Journal Article
Development of Peptide 3D Structure Mimetics: Rational Design of Novel Peptoid Cholecystokinin Receptor Antagonists
Low, Caroline M. R, Black, James W, Broughton, Howard B, Buck, Ildiko M, Davies, Jonathan M. R, Dunstone, David J, Hull, Robert A. D, Kalindjian, S. Barret, McDonald, Iain M, Pether, Michael J, Shankley, Nigel P, Steel, Katherine I. M
Published in Journal of medicinal chemistry (21.09.2000)
Published in Journal of medicinal chemistry (21.09.2000)
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Journal Article
Non-Peptide Cholecystokinin-B/Gastrin Receptor Antagonists Based on Bicyclic, Heteroaromatic Skeletons
Kalindjian, S. Barret, Buck, Ildiko M, Davies, Jonathan M. R, Dunstone, David J, Hudson, Martin L, Low, Caroline M. R, McDonald, Iain M, Pether, Michael J, Steel, Katherine I. M, Tozer, Matthew J, Vinter, J. G
Published in Journal of medicinal chemistry (26.04.1996)
Published in Journal of medicinal chemistry (26.04.1996)
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Journal Article
Improving the Affinity and Selectivity of a Nonpeptide Series of Cholecystokinin-B/Gastrin Receptor Antagonists Based on the Dibenzobicyclo[2.2.2]octane Skeleton
Kalindjian, S. Barret, Buck, Ildiko M, Cushnir, Julia R, Dunstone, David J, Hudson, Martin L, Low, Caroline M. R, McDonald, Iain M, Pether, Michael J, Steel, Katherine I. M, Tozer, Matthew J
Published in Journal of medicinal chemistry (01.10.1995)
Published in Journal of medicinal chemistry (01.10.1995)
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Journal Article
A New Class of Non-peptidic Cholecystokinin-B/Gastrin Receptor Antagonists Based on Dibenzobicyclo[2.2.2]octane
Kalindjian, S. Barret, Bodkin, Michael J, Buck, Ildiko M, Dunstone, David J, Low, Caroline M. R, McDonald, Iain M, Pether, Michael J, Steel, Katherine I. M
Published in Journal of medicinal chemistry (01.10.1994)
Published in Journal of medicinal chemistry (01.10.1994)
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Journal Article
Optimization of 1,3,4-benzotriazepine-based CCK(2) antagonists to obtain potent, orally active inhibitors of gastrin-mediated gastric acid secretion
McDonald, Iain M, Black, James W, Buck, Ildiko M, Dunstone, David J, Griffin, Eric P, Harper, Elaine A, Hull, Robert A D, Kalindjian, S Barret, Lilley, Elliot J, Linney, Ian D, Pether, Michael J, Roberts, Sonia P, Shaxted, Mark E, Spencer, John, Steel, Katherine I M, Sykes, David A, Walker, Martin K, Watt, Gillian F, Wright, Laurence, Wright, Paul T, Xun, Wei
Published in Journal of medicinal chemistry (28.06.2007)
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Published in Journal of medicinal chemistry (28.06.2007)
Journal Article
Optimization of 1,3,4-Benzotriazepine-Based CCK 2 Antagonists to Obtain Potent, Orally Active Inhibitors of Gastrin-Mediated Gastric Acid Secretion
McDonald, Iain M., Black, James W., Buck, Ildiko M., Dunstone, David J., Griffin, Eric P., Harper, Elaine A., Hull, Robert A. D., Kalindjian, S. Barret, Lilley, Elliot J., Linney, Ian D., Pether, Michael J., Roberts, Sonia P., Shaxted, Mark E., Spencer, John, Steel, Katherine I. M., Sykes, David A., Walker, Martin K., Watt, Gillian F., Wright, Laurence, Wright, Paul T., Xun, Wei
Published in Journal of medicinal chemistry (01.06.2007)
Published in Journal of medicinal chemistry (01.06.2007)
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Journal Article
omega-(Imidazol-4-yl)alkane-1-sulfonamides: a new series of potent histamine H(3) receptor antagonists
Tozer, Matthew J, Buck, Ildiko M, Cooke, Tracey, Kalindjian, S Barret, Pether, Michael J, Steel, Katherine I M
Published in Bioorganic & medicinal chemistry (01.02.2002)
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Published in Bioorganic & medicinal chemistry (01.02.2002)
Journal Article
2,7-Dioxo-2,3,4,5,6,7-hexahydro-1 H -benzo[ h ][1,4]diazonine as a New Template for the Design of CCK 2 Receptor Antagonists
McDonald, Iain M., Dunstone, David J., Kalindjian, S. Barret, Linney, Ian D., Low, Caroline M. R., Pether, Michael J., Steel, Katherine I. M., Tozer, Matthew J., Vinter, J. G.
Published in Journal of medicinal chemistry (01.09.2000)
Published in Journal of medicinal chemistry (01.09.2000)
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Journal Article
LIGANDS OF GASTRIN AND CCK RECEPTORS
DAVIES JONATHAN M. R, PETHER MICHAEL J, DUNSTONE DAVID J, KALINDJIAN SARKIS B, LOW CAROLINE M. R, TOZER MATTHEW J, STEEL KATHERINE I. M, HUDSON MARTIN L, BUCK ILDIKO M, MCDONALD IAIN M
Year of Publication 28.09.2001
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Year of Publication 28.09.2001
Patent
Tetrapeptide derivatives and analogues
MCDONALD; IAIN M, STEEL; KATHERINE I. M, BROUGHTON; HOWARD B, LOW; CAROLINE M. R, KALINDJIAN; SARKIS B, SHANKLEY; NIGEL P, BUCK; ILDIKO M, HULL; ROBERT A. D, DAVIES; JONATHAN M. R
Year of Publication 23.01.1996
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Year of Publication 23.01.1996
Patent
Bicyclo[2,2,2]octane derivatives
STEEL; KATHERINE I. M, BODKIN; MICHAEL J, PETHER; MICHAEL J, MCDONALD; IAIN M, TOZER; MATTHEW J, HARPER; ELAINE A, LOW; CAROLINE M. R, KALINDJIAN; SARKIS B, DUNSTONE; DAVID J, SHANKLEY; NIGEL P, BUCK; ILDIKO M, HULL; ROBERT A. D, DAVIES; JONATHAN M. R, HUDSON; MARTIN L
Year of Publication 07.05.1996
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Year of Publication 07.05.1996
Patent