Structure-based Drug Design Targeting an Inactive RNA Conformation: Exploiting the Flexibility of HIV-1 TAR RNA
Murchie, Alastair I.H., Davis, Ben, Isel, Catherine, Afshar, Mohammad, Drysdale, Martin J., Bower, Justin, Potter, Andrew J., Starkey, Ian D., Swarbrick, Terry M., Mirza, Shabana, Prescott, Catherine D., Vaglio, Philippe, Aboul-ela, Fareed, Karn, Jonathan
Published in Journal of molecular biology (20.02.2004)
Published in Journal of molecular biology (20.02.2004)
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Rational design of inhibitors of HIV-1 TAR RNA through the stabilisation of electrostatic "hot spots"
Davis, Ben, Afshar, Mohammad, Varani, Gabriele, Murchie, Alastair I H, Karn, Jonathan, Lentzen, Georg, Drysdale, Martin, Bower, Justin, Potter, Andrew J, Starkey, Ian D, Swarbrick, Terry, Aboul-ela, Fareed
Published in Journal of molecular biology (13.02.2004)
Published in Journal of molecular biology (13.02.2004)
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Dihydropyrancarboxamides Related to Zanamivir: A New Series of Inhibitors of Influenza Virus Sialidases. 1. Discovery, Synthesis, Biological Activity, and Structure−Activity Relationships of 4-Guanidino- and 4-Amino-4H-pyran-6-carboxamides
Smith, Paul W, Sollis, Steven L, Howes, Peter D, Cherry, Peter C, Starkey, Ian D, Cobley, Kevin N, Weston, Helen, Scicinski, Jan, Merritt, Andrew, Whittington, Andrew, Wyatt, Paul, Taylor, Neil, Green, Darren, Bethell, Richard, Madar, Safia, Fenton, Robert J, Morley, Peter J, Pateman, Tony, Beresford, Alan
Published in Journal of medicinal chemistry (12.03.1998)
Published in Journal of medicinal chemistry (12.03.1998)
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Synthesis and influenza virus sialidase inhibitory activity of the 5-desacetamido analogue of 2,3-didehydro-2,4-dideoxy-4-guanidinyl-N-acetylneuraminic acid (GG167)
Starkey, Ian D., Mahmoudian, Mahmoud, Noble, David, Smith, Paul W., Cherry, Peter C., Howes, Peter D., Sollis, Steven L.
Published in Tetrahedron letters (09.01.1995)
Published in Tetrahedron letters (09.01.1995)
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Journal Article
Dihydropyrancarboxamides Related to Zanamivir: A New Series of Inhibitors of Influenza Virus Sialidases. 1. Discovery, Synthesis, Biological Activity, and Structure−Activity Relationships of 4-Guanidino- and 4-Amino-4 H -pyran-6-carboxamides
Smith, Paul W., Sollis, Steven L., Howes, Peter D., Cherry, Peter C., Starkey, Ian D., Cobley, Kevin N., Weston, Helen, Scicinski, Jan, Merritt, Andrew, Whittington, Andrew, Wyatt, Paul, Taylor, Neil, Green, Darren, Bethell, Richard, Madar, Safia, Fenton, Robert J., Morley, Peter J., Pateman, Tony, Beresford, Alan
Published in Journal of medicinal chemistry (01.03.1998)
Published in Journal of medicinal chemistry (01.03.1998)
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Synthesis and Structure-Activity Relationships of a Series of Penicillin-Derived HIV Proteinase Inhibitors: Heterocyclic Ring Systems Containing P1' and P2' Substituents
Kitchin, John, Bethell, Richard C, Cammack, Nicholas, Dolan, Simon, Evans, Derek N, Holman, Stuart, Holmes, Duncan S, McMeekin, Peter, Mo, Chi L
Published in Journal of medicinal chemistry (01.10.1994)
Published in Journal of medicinal chemistry (01.10.1994)
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