Epigenetic Activation of Plasmacytoid DCs Drives IFNAR-Dependent Therapeutic Differentiation of AML
Salmon, Jessica M, Todorovski, Izabela, Stanley, Kym L, Bruedigam, Claudia, Kearney, Conor J, Martelotto, Luciano G, Rossello, Fernando, Semple, Timothy, Arnau, Gisela Mir, Zethoven, Magnus, Bots, Michael, Bjelosevic, Stefan, Cluse, Leonie A, Fraser, Peter J, Litalien, Veronique, Vidacs, Eva, McArthur, Kate, Matthews, Antony Y, Gressier, Elise, de Weerd, Nicole A, Lichte, Jens, Kelly, Madison J, Hogg, Simon J, Hertzog, Paul J, Kats, Lev M, Vervoort, Stephin J, De Carvalho, Daniel D, Scheu, Stefanie, Bedoui, Sammy, Kile, Benjamin T, Lane, Steven W, Perkins, Andrew C, Wei, Andrew H, Dominguez, Pilar M, Johnstone, Ricky W
Published in Cancer discovery (02.06.2022)
Published in Cancer discovery (02.06.2022)
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Inhibition of pyrimidine biosynthesis targets protein translation in acute myeloid leukemia
So, Joan, Lewis, Alexander C, Smith, Lorey K, Stanley, Kym, Franich, Rheana, Yoannidis, David, Pijpers, Lizzy, Dominguez, Pilar, Hogg, Simon J, Vervoort, Stephin J, Brown, Fiona C, Johnstone, Ricky W, McDonald, Gabrielle, Ulanet, Danielle B, Murtie, Josh, Gruber, Emily, Kats, Lev M
Published in EMBO molecular medicine (07.07.2022)
Published in EMBO molecular medicine (07.07.2022)
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Functional-genetic dissection of HDAC dependencies in mouse lymphoid and myeloid malignancies
Matthews, Geoffrey M., Mehdipour, Parinaz, Cluse, Leonie A., Falkenberg, Katrina J., Wang, Eric, Roth, Mareike, Santoro, Fabio, Vidacs, Eva, Stanley, Kym, House, Colin M., Rusche, James R., Vakoc, Christopher R., Zuber, Johannes, Minucci, Saverio, Johnstone, Ricky W.
Published in Blood (19.11.2015)
Published in Blood (19.11.2015)
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Correction to: Combining the differentiating effect of panobinostat with the apoptotic effect of arsenic trioxide leads to significant survival benefit in a model of t(8;21) acute myeloid leukemia
Salmon, Jessica M, Bots, Michael, Vidacs, Eva, Stanley, Kym L, Atadja, Peter, Zuber, Johannes, Johnstone, Ricky W
Published in Clinical epigenetics (18.11.2020)
Published in Clinical epigenetics (18.11.2020)
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Journal Article
Combination therapy of established cancer using a histone deacetylase inhibitor and a TRAIL receptor agonist
Frew, Ailsa J, Lindemann, Ralph K, Martin, Ben P, Clarke, Christopher J.P, Sharkey, Janelle, Anthony, Desiree A, Banks, Kellie-Marie, Haynes, Nicole M, Gangatirkar, Pradnya, Stanley, Kym, Bolden, Jessica E, Takeda, Kazuyoshi, Yagita, Hideo, Secrist, J. Paul, Smyth, Mark J, Johnstone, Ricky W
Published in Proceedings of the National Academy of Sciences - PNAS (12.08.2008)
Published in Proceedings of the National Academy of Sciences - PNAS (12.08.2008)
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Genomic analysis of a spontaneous model of breast cancer metastasis to bone reveals a role for the extracellular matrix
Eckhardt, Bedrich L, Parker, Belinda S, van Laar, Ryan K, Restall, Christina M, Natoli, Anthony L, Tavaria, Michael D, Stanley, Kym L, Sloan, Erica K, Moseley, Jane M, Anderson, Robin L
Published in Molecular cancer research (01.01.2005)
Published in Molecular cancer research (01.01.2005)
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Journal Article
The mTORC1 inhibitor everolimus prevents and treats Eμ-Myc lymphoma by restoring oncogene-induced senescence
Wall, Meaghan, Poortinga, Gretchen, Stanley, Kym L, Lindemann, Ralph K, Bots, Michael, Chan, Christopher J, Bywater, Megan J, Kinross, Kathryn M, Astle, Megan V, Waldeck, Kelly, Hannan, Katherine M, Shortt, Jake, Smyth, Mark J, Lowe, Scott W, Hannan, Ross D, Pearson, Richard B, Johnstone, Ricky W, McArthur, Grant A
Published in Cancer discovery (01.01.2013)
Published in Cancer discovery (01.01.2013)
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Journal Article
Combining the differentiating effect of panobinostat with the apoptotic effect of arsenic trioxide leads to significant survival benefit in a model of t(8;21) acute myeloid leukemia
Salmon, Jessica M, Bots, Michael, Vidacs, Eva, Stanley, Kym L, Atadja, Peter, Zuber, Johannes, Johnstone, Ricky W
Published in Clinical epigenetics (22.01.2015)
Published in Clinical epigenetics (22.01.2015)
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Journal Article
BET inhibitor resistance emerges from leukaemia stem cells
Fong, Chun Yew, Gilan, Omer, Lam, Enid Y N, Rubin, Alan F, Ftouni, Sarah, Tyler, Dean, Stanley, Kym, Sinha, Devbarna, Yeh, Paul, Morison, Jessica, Giotopoulos, George, Lugo, Dave, Jeffrey, Philip, Lee, Stanley Chun-Wei, Carpenter, Christopher, Gregory, Richard, Ramsay, Robert G, Lane, Steven W, Abdel-Wahab, Omar, Kouzarides, Tony, Johnstone, Ricky W, Dawson, Sarah-Jane, Huntly, Brian J P, Prinjha, Rab K, Papenfuss, Anthony T, Dawson, Mark A
Published in Nature (London) (24.09.2015)
Published in Nature (London) (24.09.2015)
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Journal Article
Differentiation therapy for the treatment of t(8;21) acute myeloid leukemia using histone deacetylase inhibitors
Bots, Michael, Verbrugge, Inge, Martin, Benjamin P., Salmon, Jessica M., Ghisi, Margherita, Baker, Adele, Stanley, Kym, Shortt, Jake, Ossenkoppele, Gert J., Zuber, Johannes, Rappaport, Amy R., Atadja, Peter, Lowe, Scott W., Johnstone, Ricky W.
Published in Blood (27.02.2014)
Published in Blood (27.02.2014)
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Functional interdependence of BRD4 and DOT1L in MLL leukemia
Gilan, Omer, Lam, Enid Y N, Becher, Isabelle, Lugo, Dave, Cannizzaro, Ester, Joberty, Gerard, Ward, Aoife, Wiese, Meike, Fong, Chun Yew, Ftouni, Sarah, Tyler, Dean, Stanley, Kym, MacPherson, Laura, Weng, Chen-Fang, Chan, Yih-Chih, Ghisi, Margherita, Smil, David, Carpenter, Christopher, Brown, Peter, Garton, Neil, Blewitt, Marnie E, Bannister, Andrew J, Kouzarides, Tony, Huntly, Brian J P, Johnstone, Ricky W, Drewes, Gerard, Dawson, Sarah-Jane, Arrowsmith, Cheryl H, Grandi, Paola, Prinjha, Rab K, Dawson, Mark A
Published in Nature structural & molecular biology (01.07.2016)
Published in Nature structural & molecular biology (01.07.2016)
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Journal Article
Inhibition of mutant IDH1 promotes cycling of acute myeloid leukemia stem cells
Gruber, Emily, So, Joan, Lewis, Alexander C., Franich, Rheana, Cole, Rachel, Martelotto, Luciano G., Rogers, Amy J., Vidacs, Eva, Fraser, Peter, Stanley, Kym, Jones, Lisa, Trigos, Anna, Thio, Niko, Li, Jason, Nicolay, Brandon, Daigle, Scott, Tron, Adriana E., Hyer, Marc L., Shortt, Jake, Johnstone, Ricky W., Kats, Lev M.
Published in Cell reports (Cambridge) (16.08.2022)
Published in Cell reports (Cambridge) (16.08.2022)
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Journal Article
Development of targeted therapies for acute myeloid leukemias
Salmon, Jessica, Bots, Michael, Verbrugge, Inge, Martin, Ben, Stanley, Kym, Baker, Adele, Vidacs, Eva, Johnstone, Ricky
Published in Experimental hematology (01.08.2013)
Published in Experimental hematology (01.08.2013)
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Journal Article
Modelling Resistance to Emerging Epigenetic Therapies
Fong, Chun Yew, Gilan, Omer, Lam, Enid, Rubin, Alan, Morison, Jessica, Giotopoulos, George, Stanley, Kym, Sarah, Ftouni, Tyler, Dean, Lugo, Dave, Jeffrey, Philip, Gregory, Richard, Schreuder, Jaring, Naik, Shalin, Kouzarides, Tony, Huntly, Brian, Johnstone, Ricky W, Prinjha, Rab K, Papenfuss, Anthony, Dawson, Mark A
Published in Blood (06.12.2014)
Published in Blood (06.12.2014)
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Abstract 4311: Utilising the preclinical VkMYC model of multiple myeloma to rapidly and effectively screen novel therapies and their combinations
Matthews, Geoffrey M., Chesi, Marta, Lefebure, Marcus, Shortt, Jake, Banks, Kellie, Stanley, Kym, Faulkner, David, Atadja, Peter, Bergsagel, Leif, Johnstone, Ricky W.
Published in Cancer research (Chicago, Ill.) (15.04.2011)
Published in Cancer research (Chicago, Ill.) (15.04.2011)
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Abstract 3110: RNA Polymerase I: A novel target in the treatment of Myc-driven malignancy
Bywater, Megan J., Poortinga, Gretchen, Cullinane, Carleen, Stanley, Kym, Walker, Rachael, Drygin, Denis, Anderes, Kenna, Johnstone, Ricky, McArthur, Grant A., Hannan, Ross D.
Published in Cancer research (Chicago, Ill.) (15.04.2010)
Published in Cancer research (Chicago, Ill.) (15.04.2010)
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Abstract B176: Synergistic induction of apoptosis by the histone-deacetylase inhibitor, Panobinostat, combined with ABT-737 or rhTRAIL, in multiple myeloma
Matthews, Geoffrey M., Shortt, Jake, Banks, Kellie M., Stanley, Kym, Faulkner, David, Bergsagel, Leif, Chesi, Marta, Atadja, Peter, Johnstone, Ricky W.
Published in Molecular cancer therapeutics (10.12.2009)
Published in Molecular cancer therapeutics (10.12.2009)
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