An allosteric modulator binds to a conformational hub in the β2 adrenergic receptor
Liu, Xiangyu, Kaindl, Jonas, Korczynska, Magdalena, Stößel, Anne, Dengler, Daniela, Stanek, Markus, Hübner, Harald, Clark, Mary J., Mahoney, Jake, Matt, Rachel Ann, Xu, Xinyu, Hirata, Kunio, Shoichet, Brian K., Sunahara, Roger K., Kobilka, Brian K., Gmeiner, Peter
Published in Nature chemical biology (01.07.2020)
Published in Nature chemical biology (01.07.2020)
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Elucidating structural determinants of biased signaling at the 5-HT1A G protein-coupled receptor through molecular dynamics simulations
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Published in Biophysical journal (08.02.2024)
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Structure-guided development of dual β2 adrenergic/dopamine D2 receptor agonists
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Published in Bioorganic & medicinal chemistry (15.06.2016)
Published in Bioorganic & medicinal chemistry (15.06.2016)
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Structure-guided development of dual beta(2) adrenergic/dopamine D-2 receptor agonists
Weichert, Dietmar, Stanek, Markus, Huebner, Harald, Gmeiner, Peter
Published in Bioorganic & medicinal chemistry (15.06.2016)
Published in Bioorganic & medicinal chemistry (15.06.2016)
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Journal Article
Structure-guided development of dual beta sub(2) adrenergic/dopamine D sub(2) receptor agonists
Weichert, Dietmar, Stanek, Markus, Huebner, Harald, Gmeiner, Peter
Published in Bioorganic & medicinal chemistry (15.06.2016)
Published in Bioorganic & medicinal chemistry (15.06.2016)
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Journal Article
Hybridization of β‑Adrenergic Agonists and Antagonists Confers G Protein Bias
Stanek, Markus, Picard, Louis-Philippe, Schmidt, Maximilian F, Kaindl, Jonas M, Hübner, Harald, Bouvier, Michel, Weikert, Dorothée, Gmeiner, Peter
Published in Journal of medicinal chemistry (23.05.2019)
Published in Journal of medicinal chemistry (23.05.2019)
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Journal Article
An allosteric modulator binds to a conformational hub in the β 2 adrenergic receptor
Liu, Xiangyu, Kaindl, Jonas, Korczynska, Magdalena, Stößel, Anne, Dengler, Daniela, Stanek, Markus, Hübner, Harald, Clark, Mary J, Mahoney, Jake, Matt, Rachel Ann, Xu, Xinyu, Hirata, Kunio, Shoichet, Brian K, Sunahara, Roger K, Kobilka, Brian K, Gmeiner, Peter
Published in Nature chemical biology (01.07.2020)
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Published in Nature chemical biology (01.07.2020)
Journal Article
Beta-2 selective adrenergic receptor agonists
Shonberg, Jeremy, Stößel, Anne, Möller, Dorothée, Gmeiner, Peter, Maul, Luis, Sunahara, Roger, Huebner, Harald, Clark, Mary Joyce, Kobilka, Brian K, Stanek, Markus
Year of Publication 28.02.2023
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Year of Publication 28.02.2023
Patent
BETA-2 SELECTIVE ADRENERGIC RECEPTOR AGONISTS
HUEBNER, Harald, SHONBERG, Jeremy, KOBILKA, Brian K, MAUL, Luis, STÖßEL, Anne, STANEK, Markus, GMEINER, Peter, SUNAHARA, Roger, MÖLLER, Dorothée, CLARK, Mary Joyce
Year of Publication 18.08.2021
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Year of Publication 18.08.2021
Patent
BETA-ADRENERGIC RECEPTOR ALLOSTERIC MODULATORS
KOBILKA, Brian K, SUNAHARA, Roger K, SHOICHET, Brian S, KORCZYNSKA, Magdalena, MAHONEY, Jacob P, CLARK, Mary J, ZHANG, Cheng, HÜBNER, Harald, STÖSSEL, Anne, LIU, Xiangyu, STANEK, Markus, GMEINER, Peter, DENGLER, Daniela, KAINDL, Jonas
Year of Publication 18.11.2021
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Year of Publication 18.11.2021
Patent
BETA-2 SELECTIVE ADRENERGIC RECEPTOR AGONISTS
HUEBNER, Harald, SHONBERG, Jeremy, KOBILKA, Brian K, MAUL, Luis, STÖßEL, Anne, STANEK, Markus, GMEINER, Peter, SUNAHARA, Roger, MÖLLER, Dorothée, CLARK, Mary Joyce
Year of Publication 19.11.2020
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Year of Publication 19.11.2020
Patent
BETA-2 SELECTIVE ADRENERGIC RECEPTOR AGONISTS
HUEBNER, Harald, SHONBERG, Jeremy, KOBILKA, Brian K, MAUL, Luis, STÖßEL, Anne, STANEK, Markus, GMEINER, Peter, SUNAHARA, Roger, MÖLLER, Dorothée, CLARK, Mary Joyce
Year of Publication 14.10.2020
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Year of Publication 14.10.2020
Patent
BETA-2 SELECTIVE ADRENERGIC RECEPTOR AGONISTS
HUEBNER, Harald, SHONBERG, Jeremy, KOBILKA, Brian K, MAUL, Luis, STÖßEL, Anne, STANEK, Markus, GMEINER, Peter, SUNAHARA, Roger, MÖLLER, Dorothée, CLARK, Mary Joyce
Year of Publication 05.03.2020
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Year of Publication 05.03.2020
Patent
BETA-ADRENERGIC RECEPTOR ALLOSTERIC MODULATORS
KORCZYNSKA, Magdalena, KOBILKA, Brian, SUNAHARA, Roger, MAHONEY, Jacob, ZHANG, Cheng, HÜBNER, Harald, SHOICHET, Brian, STÖSSEL, Anne, LIU, Xiangyu, STANEK, Markus, CLARK, Mary, GMEINER, Peter, DENGLER, Daniela, KAINDL, Jonas
Year of Publication 24.10.2019
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Year of Publication 24.10.2019
Patent
BETA-2 SELECTIVE ADRENERGIC RECEPTOR AGONISTS
HUEBNER, Harald, SHONBERG, Jeremy, KOBILKA, Brian K, MAUL, Luis, STÖßEL, Anne, STANEK, Markus, GMEINER, Peter, SUNAHARA, Roger, MÖLLER, Dorothée, CLARK, Mary Joyce
Year of Publication 13.06.2019
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Year of Publication 13.06.2019
Patent