AICAR and metformin, but not exercise, increase muscle glucose transport through AMPK-, ERK-, and PDK1-dependent activation of atypical PKC
Sajan, M. P, Bandyopadhyay, G, Miura, A, Standaert, M. L, Nimal, S, Longnus, S. L, Van Obberghen, E, Hainault, I, Foufelle, F, Kahn, R, Braun, U, Leitges, M, Farese, R. V
Published in American journal of physiology: endocrinology and metabolism (01.02.2010)
Published in American journal of physiology: endocrinology and metabolism (01.02.2010)
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Role of atypical protein kinase C in activation of sterol regulatory element binding protein-1c and nuclear factor kappa B (NFκB) in liver of rodents used as a model of diabetes, and relationships to hyperlipidaemia and insulin resistance
Sajan, M. P, Standaert, M. L, Rivas, J, Miura, A, Kanoh, Y, Soto, J, Taniguchi, C. M, Kahn, C. R, Farese, R. V
Published in Diabetologia (01.06.2009)
Published in Diabetologia (01.06.2009)
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Metformin improves atypical protein kinase C activation by insulin and phosphatidylinositol-3,4,5-(PO₄)₃ in muscle of diabetic subjects
Luna, V, Casauban, L, Sajan, M. P, Gomez-Daspet, J, Powe, J. L, Miura, A, Rivas, J, Standaert, M. L, Farese, R. V
Published in Diabetologia (01.02.2006)
Published in Diabetologia (01.02.2006)
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Insulin and PIP3 Activate PKC-ζ by Mechanisms That Are Both Dependent and Independent of Phosphorylation of Activation Loop (T410) and Autophosphorylation (T560) Sites
Standaert, Mary L, Bandyopadhyay, Gautam, Kanoh, Yoshinori, Sajan, Mini P, Farese, Robert V
Published in Biochemistry (Easton) (09.01.2001)
Published in Biochemistry (Easton) (09.01.2001)
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Combined thiazolidinedione-metformin treatment synergistically improves insulin signalling to insulin receptor substrate-1-dependent phosphatidylinositol 3-kinase, atypical protein kinase C and protein kinase B/Akt in human diabetic muscle
Temofonte, N, Sajan, M. P, Nimal, S, Pastoor, T, Fumero, C, Casaubon, L, Powe, J. L, Standaert, M. L, Farese, R. V
Published in Diabetologia (01.01.2009)
Published in Diabetologia (01.01.2009)
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Dependence of Insulin-Stimulated Glucose Transporter 4 Translocation on 3-Phosphoinositide-Dependent Protein Kinase-1 and Its Target Threonine-410 in the Activation Loop of Protein Kinase C-ζ
Bandyopadhyay, G, Standaert, M. L, Sajan, M. P, Karnitz, L. M, Cong, L, Quon, M. J, Farese, R. V
Published in Molecular endocrinology (Baltimore, Md.) (01.10.1999)
Published in Molecular endocrinology (Baltimore, Md.) (01.10.1999)
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Impaired Activation of Protein Kinase C-ζ by Insulin and Phosphatidylinositol-3,4,5-(PO4)3 in Cultured Preadipocyte-Derived Adipocytes and Myotubes of Obese Subjects
Sajan, M. P, Standaert, M. L, Miura, A, Bandyopadhyay, G, Vollenweider, P, Franklin, D. M, Lea-Currie, R, Farese, R. V
Published in The journal of clinical endocrinology and metabolism (01.08.2004)
Published in The journal of clinical endocrinology and metabolism (01.08.2004)
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Chronic activation of protein kinase C in soleus muscles and other tissues of insulin-resistant type II diabetic Goto-Kakizaki (GK), obese/aged, and obese/Zucker rats. A mechanism for inhibiting glycogen synthesis
A Avignon, K Yamada, X Zhou, B Spencer, O Cardona, S Saba-Siddique, L Galloway, M L Standaert, R V Farese
Published in Diabetes (New York, N.Y.) (01.10.1996)
Published in Diabetes (New York, N.Y.) (01.10.1996)
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Okadaic acid activates atypical protein kinase C (zeta/lambda) in rat and 3T3/L1 adipocytes. An apparent requirement for activation of Glut4 translocation and glucose transport
Standaert, M L, Bandyopadhyay, G, Sajan, M P, Cong, L, Quon, M J, Farese, R V
Published in The Journal of biological chemistry (14.05.1999)
Published in The Journal of biological chemistry (14.05.1999)
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Insulin-induced activation of glycerol-3-phosphate acyltransferase by a chiro-inositol-containing insulin mediator is defective in adipocytes of insulin-resistant, type II diabetic, Goto-Kakizaki rats
Farese, R.V, Standaert, M.L, Yamada, K, Huang, L.C, Zhang, C, Cooper, D.R, Wang, Z, Yang, Y, Suzuki, S, Toyota, T, Larner, J
Published in Proceedings of the National Academy of Sciences - PNAS (08.11.1994)
Published in Proceedings of the National Academy of Sciences - PNAS (08.11.1994)
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Insulin increases membrane and cytosolic protein kinase C activity in BC3H-1 myocytes
Cooper, D.R., Konda, T.S., Standaert, M.L., Davis, J.S., Pollet, R.J., Farese, R.V.
Published in The Journal of biological chemistry (15.03.1987)
Published in The Journal of biological chemistry (15.03.1987)
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Role of protein kinase C in insulin's regulation of c-fos transcription
MESSINA, J. L, STANDAERT, M. L, ISHIZUKA, T, WEINSTOCK, R. S, FARESE, R. V
Published in The Journal of biological chemistry (05.05.1992)
Published in The Journal of biological chemistry (05.05.1992)
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Journal Article
Protein kinase C-zeta as a downstream effector of phosphatidylinositol 3-kinase during insulin stimulation in rat adipocytes. Potential role in glucose transport
Standaert, M L, Galloway, L, Karnam, P, Bandyopadhyay, G, Moscat, J, Farese, R V
Published in The Journal of biological chemistry (28.11.1997)
Published in The Journal of biological chemistry (28.11.1997)
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Journal Article
Evidence for involvement of protein kinase C (PKC)-zeta and noninvolvement of diacylglycerol-sensitive PKCs in insulin-stimulated glucose transport in L6 myotubes
Bandyopadhyay, G, Standaert, M L, Galloway, L, Moscat, J, Farese, R V
Published in Endocrinology (Philadelphia) (01.11.1997)
Published in Endocrinology (Philadelphia) (01.11.1997)
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The mechanism of insulin stimulation of (Na+,K+)-ATPase transport activity in muscle
Rosić, N K, Standaert, M L, Pollet, R J
Published in The Journal of biological chemistry (25.05.1985)
Published in The Journal of biological chemistry (25.05.1985)
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Insulin-induced glycerolipid mediators and the stimulation of glucose transport in BC3H-1 myocytes
Standaert, M L, Farese, R V, Cooper, D R, Pollet, R J
Published in The Journal of biological chemistry (25.06.1988)
Published in The Journal of biological chemistry (25.06.1988)
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