The Metabolic Syndrome in Men study: a resource for studies of metabolic and cardiovascular diseases
Laakso, Markku, Kuusisto, Johanna, Stančáková, Alena, Kuulasmaa, Teemu, Pajukanta, Päivi, Lusis, Aldons J., Collins, Francis S., Mohlke, Karen L., Boehnke, Michael
Published in Journal of lipid research (01.03.2017)
Published in Journal of lipid research (01.03.2017)
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Heterozygous RFX6 protein truncating variants are associated with MODY with reduced penetrance
Patel, Kashyap A., Kettunen, Jarno, Laakso, Markku, Stančáková, Alena, Laver, Thomas W., Colclough, Kevin, Johnson, Matthew B., Abramowicz, Marc, Groop, Leif, Miettinen, Päivi J., Shepherd, Maggie H., Flanagan, Sarah E., Ellard, Sian, Inagaki, Nobuya, Hattersley, Andrew T., Tuomi, Tiinamaija, Cnop, Miriam, Weedon, Michael N.
Published in Nature communications (12.10.2017)
Published in Nature communications (12.10.2017)
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Exome array analysis identifies new loci and low-frequency variants influencing insulin processing and secretion
Huyghe, Jeroen R, Jackson, Anne U, Fogarty, Marie P, Buchkovich, Martin L, Stančáková, Alena, Stringham, Heather M, Sim, Xueling, Yang, Lingyao, Fuchsberger, Christian, Cederberg, Henna, Chines, Peter S, Teslovich, Tanya M, Romm, Jane M, Ling, Hua, McMullen, Ivy, Ingersoll, Roxann, Pugh, Elizabeth W, Doheny, Kimberly F, Neale, Benjamin M, Daly, Mark J, Kuusisto, Johanna, Scott, Laura J, Kang, Hyun Min, Collins, Francis S, Abecasis, Gonçalo R, Watanabe, Richard M, Boehnke, Michael, Laakso, Markku, Mohlke, Karen L
Published in Nature genetics (01.02.2013)
Published in Nature genetics (01.02.2013)
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Plasma Mannose Levels Are Associated with Incident Type 2 Diabetes and Cardiovascular Disease
Mardinoglu, Adil, Stančáková, Alena, Lotta, Luca A., Kuusisto, Johanna, Boren, Jan, Blüher, Matthias, Wareham, Nicholas J., Ferrannini, Ele, Groop, Per Henrik, Laakso, Markku, Langenberg, Claudia, Smith, Ulf
Published in Cell metabolism (01.08.2017)
Published in Cell metabolism (01.08.2017)
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Decreased plasma β‐amyloid in the Alzheimer's disease APP A673T variant carriers
Martiskainen, Henna, Herukka, Sanna‐Kaisa, Stančáková, Alena, Paananen, Jussi, Soininen, Hilkka, Kuusisto, Johanna, Laakso, Markku, Hiltunen, Mikko
Published in Annals of neurology (01.07.2017)
Published in Annals of neurology (01.07.2017)
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Link Between GIP and Osteopontin in Adipose Tissue and Insulin Resistance
AHLQVIST, Emma, OSMARK, Peter, HANSSON, Ola, KUUSISTO, Johanna, KIEFFER, Timothy J, TUOMI, Tiinamaija, ISOMAA, Bo, MADSBAD, Sten, GOMEZ, Maria F, POULSEN, Pernille, LAAKSO, Markku, DEGERMAN, Eva, KUULASMAA, Tiina, PIHLAJAMÄKI, Jussi, WIERUP, Nils, VAAG, Allan, GROOP, Leif, LYSSENKO, Valeriya, PILGAARD, Kasper, OMAR, Bilal, BRØNS, Charlotte, KOTOVA, Olga, ZETTERQVIST, Anna V, STANCAKOVA, Alena, JONSSON, Anna
Published in Diabetes (New York, N.Y.) (01.06.2013)
Published in Diabetes (New York, N.Y.) (01.06.2013)
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SIRT3 Deficiency and Mitochondrial Protein Hyperacetylation Accelerate the Development of the Metabolic Syndrome
Hirschey, Matthew D., Shimazu, Tadahiro, Jing, Enxuan, Grueter, Carrie A., Collins, Amy M., Aouizerat, Bradley, Stančáková, Alena, Goetzman, Eric, Lam, Maggie M., Schwer, Bjoern, Stevens, Robert D., Muehlbauer, Michael J., Kakar, Sanjay, Bass, Nathan M., Kuusisto, Johanna, Laakso, Markku, Alt, Frederick W., Newgard, Christopher B., Farese, Robert V., Kahn, C. Ronald, Verdin, Eric
Published in Molecular cell (21.10.2011)
Published in Molecular cell (21.10.2011)
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Associations of multiple lipoprotein and apolipoprotein measures with worsening of glycemia and incident type 2 diabetes in 6607 non-diabetic Finnish men
Fizelova, Maria, Miilunpohja, Manna, Kangas, Antti J, Soininen, Pasi, Kuusisto, Johanna, Ala-Korpela, Mika, Laakso, Markku, Stančáková, Alena
Published in Atherosclerosis (01.05.2015)
Published in Atherosclerosis (01.05.2015)
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Genome-Wide Screen for Metabolic Syndrome Susceptibility Loci Reveals Strong Lipid Gene Contribution But No Evidence for Common Genetic Basis for Clustering of Metabolic Syndrome Traits
Kristiansson, Kati, Perola, Markus, Tikkanen, Emmi, Kettunen, Johannes, Surakka, Ida, Havulinna, Aki S, Stančáková, Alena, Barnes, Chris, Widen, Elisabeth, Kajantie, Eero, Eriksson, Johan G, Viikari, Jorma, Kähönen, Mika, Lehtimäki, Terho, Raitakari, Olli T, Hartikainen, Anna-Liisa, Ruokonen, Aimo, Pouta, Anneli, Jula, Antti, Kangas, Antti J, Soininen, Pasi, Ala-Korpela, Mika, Männistö, Satu, Jousilahti, Pekka, Bonnycastle, Lori L, Järvelin, Marjo-Riitta, Kuusisto, Johanna, Collins, Francis S, Laakso, Markku, Hurles, Matthew E, Palotie, Aarno, Peltonen, Leena, Ripatti, Samuli, Salomaa, Veikko
Published in Circulation. Cardiovascular genetics (01.04.2012)
Published in Circulation. Cardiovascular genetics (01.04.2012)
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Clinical, Genetic, and Biochemical Characteristics of Early-Onset Diabetes in the Finnish Population
Huopio, Hanna, Miettinen, Päivi J, Ilonen, Jorma, Nykänen, Päivi, Veijola, Riitta, Keskinen, Päivi, Näntö-Salonen, Kirsti, Vangipurapu, Jagadish, Raivo, Joose, Stančáková, Alena, Männistö, Jonna, Kuulasmaa, Teemu, Knip, Mikael, Otonkoski, Timo, Laakso, Markku
Published in The journal of clinical endocrinology and metabolism (01.08.2016)
Published in The journal of clinical endocrinology and metabolism (01.08.2016)
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Identification of seven novel loci associated with amino acid levels using single-variant and gene-based tests in 8545 Finnish men from the METSIM study
Teslovich, Tanya M, Kim, Daniel Seung, Yin, Xianyong, Stančáková, Alena, Jackson, Anne U, Wielscher, Matthias, Naj, Adam, Perry, John R B, Huyghe, Jeroen R, Stringham, Heather M, Davis, James P, Raulerson, Chelsea K, Welch, Ryan P, Fuchsberger, Christian, Locke, Adam E, Sim, Xueling, Chines, Peter S, Narisu, Narisu, Kangas, Antti J, Soininen, Pasi, Ala-Korpela, Mika, Gudnason, Vilmundur, Musani, Solomon K, Jarvelin, Marjo-Riitta, Schellenberg, Gerard D, Speliotes, Elizabeth K, Kuusisto, Johanna, Collins, Francis S, Boehnke, Michael, Laakso, Markku, Mohlke, Karen L
Published in Human molecular genetics (01.05.2018)
Published in Human molecular genetics (01.05.2018)
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Elevated Plasma Levels of 3-Hydroxyisobutyric Acid Are Associated With Incident Type 2 Diabetes
Mardinoglu, Adil, Gogg, Silvia, Lotta, Luca A., Stančáková, Alena, Nerstedt, Annika, Boren, Jan, Blüher, Matthias, Ferrannini, Ele, Langenberg, Claudia, Wareham, Nicholas J., Laakso, Markku, Smith, Ulf
Published in EBioMedicine (01.01.2018)
Published in EBioMedicine (01.01.2018)
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Glycated Hemoglobin Levels Are Mostly Dependent on Nonglycemic Parameters in 9398 Finnish Men Without Diabetes
Fizelova, Maria, Stančáková, Alena, Lorenzo, Carlos, Haffner, Steven M, Cederberg, Henna, Kuusisto, Johanna, Laakso, Markku
Published in The journal of clinical endocrinology and metabolism (01.05.2015)
Published in The journal of clinical endocrinology and metabolism (01.05.2015)
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Journal Article
Pleiotropic Effects of GIP on Islet Function Involve Osteopontin
LYSSENKO, Valeriya, ELIASSON, Lena, TANEERA, Jalal, BALHUIZEN, Alexander, HANSSON, Ola, OSMARK, Peter, DUNER, Pontus, BRØNS, Charlotte, STANCAKOVA, Alena, KUUSISTO, Johanna, BUGLIANI, Marco, SAXENA, Richa, KOTOVA, Olga, AHLQVIST, Emma, KIEFFER, Timothy J, TUOMI, Tiinamaija, ISOMAA, Bo, MELANDER, Olle, SONESTEDT, Emily, ORHO-MELANDER, Marju, NILSSON, Peter, BONETTI, Sara, BONADONNA, Riccardo, PILGAARD, Kasper, MICCOLI, Roberto, DELPRATO, Stefano, MARCHETTI, Piero, MADSBAD, Sten, POULSEN, Pernille, VAAG, Allan, LAAKSO, Markku, GOMEZ, Maria F, GROOP, Leif, WIERUP, Nils, SALEHI, Albert, WENDT, Anna, JONSSON, Anna, DE MARINIS, Yang Z, BERGLUND, Lisa M
Published in Diabetes (New York, N.Y.) (01.09.2011)
Published in Diabetes (New York, N.Y.) (01.09.2011)
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Increased risk of diabetes with statin treatment is associated with impaired insulin sensitivity and insulin secretion: a 6 year follow-up study of the METSIM cohort
Cederberg, Henna, Stančáková, Alena, Yaluri, Nagendra, Modi, Shalem, Kuusisto, Johanna, Laakso, Markku
Published in Diabetologia (01.05.2015)
Published in Diabetologia (01.05.2015)
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Non-cholesterol sterol levels predict hyperglycemia and conversion to type 2 diabetes in Finnish men
Cederberg, Henna, Gylling, Helena, Miettinen, Tatu A, Paananen, Jussi, Vangipurapu, Jagadish, Pihlajamäki, Jussi, Kuulasmaa, Teemu, Stančáková, Alena, Smith, Ulf, Kuusisto, Johanna, Laakso, Markku
Published in PloS one (28.06.2013)
Published in PloS one (28.06.2013)
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A Common Variant in TFB1M Is Associated with Reduced Insulin Secretion and Increased Future Risk of Type 2 Diabetes
Koeck, Thomas, Olsson, Anders H., Nitert, Marloes Dekker, Sharoyko, Vladimir V., Ladenvall, Claes, Kotova, Olga, Reiling, Erwin, Rönn, Tina, Parikh, Hemang, Taneera, Jalal, Eriksson, Johan G., Metodiev, Metodi D., Larsson, Nils-Göran, Balhuizen, Alexander, Luthman, Holger, Stančáková, Alena, Kuusisto, Johanna, Laakso, Markku, Poulsen, Pernille, Vaag, Allan, Groop, Leif, Lyssenko, Valeriya, Mulder, Hindrik, Ling, Charlotte
Published in Cell metabolism (05.01.2011)
Published in Cell metabolism (05.01.2011)
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The cancer-associated FGFR4-G388R polymorphism enhances pancreatic insulin secretion and modifies the risk of diabetes
Ezzat, Shereen, Zheng, Lei, Florez, Jose C, Stefan, Norbert, Mayr, Thomas, Hliang, Maw Maw, Jablonski, Kathleen, Harden, Maegan, Stančáková, Alena, Laakso, Markku, Haring, Hans-Ulrich, Ullrich, Axel, Asa, Sylvia L
Published in Cell metabolism (04.06.2013)
Published in Cell metabolism (04.06.2013)
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Association analysis of 29,956 individuals confirms that a low-frequency variant at CCND2 halves the risk of type 2 diabetes by enhancing insulin secretion
Yaghootkar, Hanieh, Stancáková, Alena, Freathy, Rachel M, Vangipurapu, Jagadish, Weedon, Michael N, Xie, Weijia, Wood, Andrew R, Ferrannini, Ele, Mari, Andrea, Ring, Susan M, Lawlor, Debbie A, Davey Smith, George, Jørgensen, Torben, Hansen, Torben, Pedersen, Oluf, Steinthorsdottir, Valgerdur, Guðbjartsson, Daniel F, Thorleifsson, Gudmar, Thorsteinsdottir, Unnur, Stefansson, Kari, Hattersley, Andrew T, Walker, Mark, Morris, Andrew D, McCarthy, Mark I, Palmer, Colin N A, Laakso, Markku, Frayling, Timothy M
Published in Diabetes (New York, N.Y.) (01.06.2015)
Published in Diabetes (New York, N.Y.) (01.06.2015)
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