DFT Computational Study of the Methanolytic Cleavage of DNA and RNA Phosphodiester Models Promoted by the Dinuclear Zn(II) Complex of 1,3-Bis(1,5,9-triazacyclododec-1-yl)propane
Maxwell, Christopher I, Mosey, Nicholas J, Stan Brown, R
Published in Journal of the American Chemical Society (13.11.2013)
Published in Journal of the American Chemical Society (13.11.2013)
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Cu(II)-Promoted Methanolysis of N,N-Dipicolylacetamide. Multistep Activation by Decoupling of >N̈–CO Resonance via Cu(II)–N Binding, Delivery of the Cu(II):(−OCH3) Nucleophile, and Metal Ion Assistance of the Departure of the Leaving Group
Barrera, Isabel Frances, Maxwell, Christopher I, Neverov, Alexei A, Brown, R. Stan
Published in Journal of organic chemistry (20.04.2012)
Published in Journal of organic chemistry (20.04.2012)
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Journal Article
Cu(II)-Promoted Methanolysis of N,N‑Bis(2-picolyl)carbamates: Rate-Limiting Metal Ion Delivery of Coordinated Alcoholate Nucleophile Followed by Fast Partitioning of a Tetrahedral Intermediate
Neverov, Alexei A, Cimpean, Luana, Chiykowski, Valerie, Vance, Tyler, Brown, R. Stan
Published in Journal of organic chemistry (06.02.2015)
Published in Journal of organic chemistry (06.02.2015)
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Journal Article
The Dinuclear Zn(II) Complex Catalyzed Cyclization of a Series of 2-Hydroxypropyl Aryl Phosphate RNA Models: Progressive Change in Mechanism from Rate-Limiting P−O Bond Cleavage to Substrate Binding
Bunn, Shannon E, Liu, C. Tony, Lu, Zhong-Lin, Neverov, Alexei A, Brown, R. Stan
Published in Journal of the American Chemical Society (26.12.2007)
Published in Journal of the American Chemical Society (26.12.2007)
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Journal Article
Density functional theory study of methoxide promoted and Zn(II)-complexed methoxide promoted cleavages of aryl- and alkyl acetates in methanol. Transition from concerted to stepwise processes as a function of leaving group ability
Maxwell, Christopher I., Neverov, Alexei A., Mosey, Nicholas J., Stan Brown, R.
Published in Journal of physical organic chemistry (01.05.2014)
Published in Journal of physical organic chemistry (01.05.2014)
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Journal Article
Demonstration of Prominent Cu(II)-Promoted Leaving Group Stabilization of the Cleavage of a Homologous Set of Phosphate Mono-, Di-, and Triesters in Methanol
Liu, C. Tony, Neverov, Alexei A, Maxwell, Christopher I, Brown, R. Stan
Published in Journal of the American Chemical Society (17.03.2010)
Published in Journal of the American Chemical Society (17.03.2010)
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Journal Article
Trifunctional Metal Ion-Catalyzed Solvolysis: Cu(II)-Promoted Methanolysis of N,N‑bis(2-picolyl) Benzamides Involves Unusual Lewis Acid Activation of Substrate, Delivery of Coordinated Nucleophile, Powerful Assistance of the Leaving Group Departure
Raycroft, Mark A. R, Maxwell, Christopher I, Oldham, Robyn A. A, Andrea, Areen Saffouri, Neverov, Alexei A, Brown, R. Stan
Published in Inorganic chemistry (01.10.2012)
Published in Inorganic chemistry (01.10.2012)
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Journal Article
Leaving Group Assistance in the La3+-Catalyzed Cleavage of Dimethyl (o-Methoxycarbonyl)aryl Phosphate Triesters in Methanol
Edwards, David R, Liu, C. Tony, Garrett, Graham E, Neverov, Alexei A, Brown, R. Stan
Published in Journal of the American Chemical Society (30.09.2009)
Published in Journal of the American Chemical Society (30.09.2009)
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Journal Article
Kinetic resolution of esters via metal catalyzed methanolysis reactions
Maxwell, Christopher I, Shah, Kalpa, Samuleev, Pavel V, Neverov, Alexei A, Brown, R Stan
Published in Organic & biomolecular chemistry (01.01.2008)
Published in Organic & biomolecular chemistry (01.01.2008)
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Journal Article
Rapid Three-Step Cleavage of RNA and DNA Model Systems Promoted by a Dinuclear Cu(II) Complex in Methanol. Energetic Origins of the Catalytic Efficacy
Lu, Zhong-Lin, Liu, C. Tony, Neverov, Alexei A, Brown, R. Stan
Published in Journal of the American Chemical Society (19.09.2007)
Published in Journal of the American Chemical Society (19.09.2007)
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Journal Article
Biomimetic Cleavage of RNA Models Promoted by a Dinuclear Zn(II) Complex in Ethanol. Greater than 30 kcal/mol Stabilization of the Transition State for Cleavage of a Phosphate Diester
Liu, C. Tony, Neverov, Alexei A, Brown, R. Stan
Published in Journal of the American Chemical Society (10.12.2008)
Published in Journal of the American Chemical Society (10.12.2008)
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Journal Article
Combination of a dinuclear Zn2+ complex and a medium effect exerts a 10(12)-fold rate enhancement of cleavage of an RNA and DNA model system
Neverov, Alexei A, Lu, Zhong-Lin, Maxwell, Christopher I, Mohamed, Mark F, White, Christopher J, Tsang, Josephine S W, Brown, R Stan
Published in Journal of the American Chemical Society (20.12.2006)
Published in Journal of the American Chemical Society (20.12.2006)
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