Spinal NK-1 receptor-expressing neurons and descending pathways support fentanyl-induced pain hypersensitivity in a rat model of postoperative pain
Rivat, Cyril, Vera-Portocarrero, Louis P., Ibrahim, Mohab M., Mata, Heriberto P., Stagg, Nicola J., De Felice, Milena, Porreca, Frank, Malan, T. P.
Published in The European journal of neuroscience (01.02.2009)
Published in The European journal of neuroscience (01.02.2009)
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Journal Article
Membrane-Proximal Epitope Facilitates Efficient T Cell Synapse Formation by Anti-FcRH5/CD3 and Is a Requirement for Myeloma Cell Killing
Li, Ji, Stagg, Nicola J., Johnston, Jennifer, Harris, Michael J., Menzies, Sam A., DiCara, Danielle, Clark, Vanessa, Hristopoulos, Maria, Cook, Ryan, Slaga, Dionysos, Nakamura, Rin, McCarty, Luke, Sukumaran, Siddharth, Luis, Elizabeth, Ye, Zhengmao, Wu, Thomas D., Sumiyoshi, Teiko, Danilenko, Dimitry, Lee, Genee Y., Totpal, Klara, Ellerman, Diego, Hötzel, Isidro, James, John R., Junttila, Teemu T.
Published in Cancer cell (13.03.2017)
Published in Cancer cell (13.03.2017)
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Journal Article
Microtubule and tubulin binding and regulation of microtubule dynamics by the antibody drug conjugate (ADC) payload, monomethyl auristatin E (MMAE): Mechanistic insights into MMAE ADC peripheral neuropathy
Best, Rebecca L., LaPointe, Nichole E., Azarenko, Olga, Miller, Herb, Genualdi, Christine, Chih, Stephen, Shen, Ben-Quan, Jordan, Mary Ann, Wilson, Leslie, Feinstein, Stuart C., Stagg, Nicola J.
Published in Toxicology and applied pharmacology (15.06.2021)
Published in Toxicology and applied pharmacology (15.06.2021)
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Journal Article
Regular Exercise Reverses Sensory Hypersensitivity in a Rat Neuropathic Pain Model: Role of Endogenous Opioids
STAGG, Nicola J, MATA, Heriberto P, IBRAHIM, Mohab M, HENRIKSEN, Erik J, PORRECA, Frank, VANDERAH, Todd W, PHILIP MALAN, T
Published in Anesthesiology (Philadelphia) (01.04.2011)
Published in Anesthesiology (Philadelphia) (01.04.2011)
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Journal Article
Nonclinical toxicology development of a novel antibody antibiotic conjugate for treating invasive Staphylococcus Aureus infections
Stagg, Nicola J., Katavolos, Paula, Achilles Poon, Kirsten, Zhong, Shelly, Ljumanovic, Nina, Kamath, Amrita, Cai, Hao, Carrasco-Triguero, Montserrat, Halpern, Wendy
Published in Toxicology and applied pharmacology (15.01.2022)
Published in Toxicology and applied pharmacology (15.01.2022)
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Journal Article
Peripheral neuropathy with microtubule inhibitor containing antibody drug conjugates: Challenges and perspectives in translatability from nonclinical toxicology studies to the clinic
Stagg, Nicola J., Shen, Ben-Quan, Brunstein, Flavia, Li, Chunze, Kamath, Amrita V., Zhong, Fiona, Schutten, Melissa, Fine, Bernard M.
Published in Regulatory toxicology and pharmacology (01.12.2016)
Published in Regulatory toxicology and pharmacology (01.12.2016)
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Journal Article
Predictivity/Translatability of Toxicities Observed in Nonclinical Toxicology Studies to Clinical Safety Outcomes in Drug Development: Case Examples
Stagg, Nicola J, Ghantous, Hanan N, Roth, Robert, Hastings, Kenneth L
Published in International journal of toxicology (01.03.2020)
Published in International journal of toxicology (01.03.2020)
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Journal Article
Antibody–Drug Conjugates Derived from Cytotoxic seco-CBI-Dimer Payloads Are Highly Efficacious in Xenograft Models and Form Protein Adducts In Vivo
Su, Dian, Chen, Jinhua, Cosino, Ely, dela Cruz-Chuh, Josefa, Davis, Helen, Del Rosario, Geoffrey, Figueroa, Isabel, Goon, Leanne, He, Jintang, Kamath, Amrita V, Kaur, Surinder, Kozak, Katherine R, Lau, Jeffrey, Lee, Donna, Lee, M. Violet, Leipold, Douglas, Liu, Luna, Liu, Peter, Lu, Guo-Liang, Nelson, Chris, Ng, Carl, Pillow, Thomas H, Polakis, Paul, Polson, Andrew G, Rowntree, Rebecca K, Saad, Ola, Safina, Brian, Stagg, Nicola J, Tercel, Moana, Vandlen, Richard, Vollmar, Breanna S, Wai, John, Wang, Tao, Wei, BinQing, Xu, Keyang, Xue, Juanjuan, Xu, Zijin, Yan, Gang, Yao, Hui, Yu, Shang-Fan, Zhang, Donglu, Zhong, Fiona, Dragovich, Peter S
Published in Bioconjugate chemistry (15.05.2019)
Published in Bioconjugate chemistry (15.05.2019)
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Journal Article
CB2 cannabinoid receptor mediation of antinociception
IBRAHIM, Mohab M, RUDE, Megan L, STAGG, Nicola J, MATA, Heriberto P, LAI, Josephine, VANDERAH, Todd W, PORRECA, Frank, BUCKLEY, Nancy E, MAKRIYANNIS, Alexandros, MALAN, T. Philip
Published in Pain (Amsterdam) (01.05.2006)
Published in Pain (Amsterdam) (01.05.2006)
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Journal Article
Exploration of Pyrrolobenzodiazepine (PBD)-Dimers Containing Disulfide-Based Prodrugs as Payloads for Antibody–Drug Conjugates
Pei, Zhonghua, Chen, Chunjiao, Chen, Jinhua, Cruz-Chuh, Josefa dela, Delarosa, Reginald, Deng, Yuzhong, Fourie-O’Donohue, Aimee, Figueroa, Isabel, Guo, Jun, Jin, Weiwei, Khojasteh, S. Cyrus, Kozak, Katherine R, Latifi, Brandon, Lee, James, Li, Guangmin, Lin, Eva, Liu, Liling, Lu, Jiawei, Martin, Scott, Ng, Carl, Nguyen, Trung, Ohri, Rachana, Lewis Phillips, Gail, Pillow, Thomas H, Rowntree, Rebecca K, Stagg, Nicola J, Stokoe, David, Ulufatu, Sheila, Verma, Vishal A, Wai, John, Wang, Jing, Xu, Keyang, Xu, Zijin, Yao, Hui, Yu, Shang-Fan, Zhang, Donglu, Dragovich, Peter S
Published in Molecular pharmaceutics (04.09.2018)
Published in Molecular pharmaceutics (04.09.2018)
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Journal Article
Acute and 28-day repeated dose toxicology studies in mice with aryloxyalkanoate dioxygenase (AAD-1) protein expressed in 2,4-D tolerant DAS-40278-9 maize
Stagg, Nicola J., Thomas, Johnson, Herman, Rod A., Juberg, Daland R.
Published in Regulatory toxicology and pharmacology (01.03.2012)
Published in Regulatory toxicology and pharmacology (01.03.2012)
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Journal Article
An Anti-B7-H4 Antibody–Drug Conjugate for the Treatment of Breast Cancer
Leong, Steven R, Liang, Wei-Ching, Wu, Yan, Crocker, Lisa, Cheng, Eric, Sampath, Deepak, Ohri, Rachana, Raab, Helga, Hass, Philip E, Pham, Thinh, Firestein, Ron, Li, Dongwei, Schutten, Melissa, Stagg, Nicola J, Ogasawara, Annie, Koppada, Neelima, Roth, Leslie, Williams, Simon P, Lee, Byoung-Chul, Chalouni, Cecile, Peng, Ivan, DeVoss, Jason, Tremayne, Jarrod, Polakis, Paul, Polson, Andrew G
Published in Molecular pharmaceutics (01.06.2015)
Published in Molecular pharmaceutics (01.06.2015)
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Journal Article
Workshop proceedings: challenges and opportunities in evaluating protein allergenicity across biotechnology industries
Stagg, Nicola J, Ghantous, Hanan N, Ladics, Gregory S, House, Robert V, Gendel, Steven M, Hastings, Kenneth L
Published in International journal of toxicology (01.01.2013)
Published in International journal of toxicology (01.01.2013)
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Journal Article
CB 2 cannabinoid receptor mediation of antinociception
Ibrahim, Mohab M., Rude, Megan L., Stagg, Nicola J., Mata, Heriberto P., Lai, Josephine, Vanderah, Todd W., Porreca, Frank, Buckley, Nancy E., Makriyannis, Alexandros, Malan, T. Philip
Published in Pain (Amsterdam) (2006)
Published in Pain (Amsterdam) (2006)
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Journal Article