Phosphoproteome profiling uncovers a key role for CDKs in TNF signaling
Tanzer, Maria C., Bludau, Isabell, Stafford, Che A., Hornung, Veit, Mann, Matthias
Published in Nature communications (18.10.2021)
Published in Nature communications (18.10.2021)
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Journal Article
Oligomerization‐driven MLKL ubiquitylation antagonizes necroptosis
Liu, Zikou, Dagley, Laura F, Shield‐Artin, Kristy, Young, Samuel N, Bankovacki, Aleksandra, Wang, Xiangyi, Tang, Michelle, Howitt, Jason, Stafford, Che A, Nachbur, Ueli, Fitzgibbon, Cheree, Garnish, Sarah E, Webb, Andrew I, Komander, David, Murphy, James M, Hildebrand, Joanne M, Silke, John
Published in The EMBO journal (01.12.2021)
Published in The EMBO journal (01.12.2021)
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Journal Article
Parkin inhibits BAK and BAX apoptotic function by distinct mechanisms during mitophagy
Bernardini, Jonathan P, Brouwer, Jason M, Tan, Iris KL, Sandow, Jarrod J, Huang, Shuai, Stafford, Che A, Bankovacki, Aleksandra, Riffkin, Christopher D, Wardak, Ahmad Z, Czabotar, Peter E, Lazarou, Michael, Dewson, Grant
Published in The EMBO journal (15.01.2019)
Published in The EMBO journal (15.01.2019)
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Journal Article
NOD Signaling and Cell Death
Heim, Valentin J., Stafford, Che A., Nachbur, Ueli
Published in Frontiers in cell and developmental biology (02.10.2019)
Published in Frontiers in cell and developmental biology (02.10.2019)
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Journal Article
IAPs Regulate Distinct Innate Immune Pathways to Co-ordinate the Response to Bacterial Peptidoglycans
Stafford, Che A., Lawlor, Kate E., Heim, Valentin J., Bankovacki, Aleksandra, Bernardini, Jonathan P., Silke, John, Nachbur, Ueli
Published in Cell reports (Cambridge) (06.02.2018)
Published in Cell reports (Cambridge) (06.02.2018)
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Journal Article
IKKβ primes inflammasome formation by recruiting NLRP3 to the trans-Golgi network
Schmacke, Niklas A., O’Duill, Fionan, Gaidt, Moritz M., Szymanska, Inga, Kamper, Julia M., Schmid-Burgk, Jonathan L., Mädler, Sophia C., Mackens-Kiani, Timur, Kozaki, Tatsuya, Chauhan, Dhruv, Nagl, Dennis, Stafford, Che A., Harz, Hartmann, Fröhlich, Adrian L., Pinci, Francesca, Ginhoux, Florent, Beckmann, Roland, Mann, Matthias, Leonhardt, Heinrich, Hornung, Veit
Published in Immunity (Cambridge, Mass.) (13.12.2022)
Published in Immunity (Cambridge, Mass.) (13.12.2022)
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Journal Article
Phosphorylation of muramyl peptides by NAGK is required for NOD2 activation
Stafford, Che A., Gassauer, Alicia-Marie, de Oliveira Mann, Carina C., Tanzer, Maria C., Fessler, Evelyn, Wefers, Benedikt, Nagl, Dennis, Kuut, Gunnar, Sulek, Karolina, Vasilopoulou, Catherine, Schwojer, Sophia J., Wiest, Andreas, Pfautsch, Marie K., Wurst, Wolfgang, Yabal, Monica, Fröhlich, Thomas, Mann, Matthias, Gisch, Nicolas, Jae, Lucas T., Hornung, Veit
Published in Nature (London) (15.09.2022)
Published in Nature (London) (15.09.2022)
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Journal Article
A RIPK2 inhibitor delays NOD signalling events yet prevents inflammatory cytokine production
Nachbur, Ueli, Stafford, Che A., Bankovacki, Aleksandra, Zhan, Yifan, Lindqvist, Lisa M., Fiil, Berthe K., Khakham, Yelena, Ko, Hyun-Ja, Sandow, Jarrod J., Falk, Hendrik, Holien, Jessica K., Chau, Diep, Hildebrand, Joanne, Vince, James E., Sharp, Phillip P., Webb, Andrew I., Jackman, Katherine A., Mühlen, Sabrina, Kennedy, Catherine L., Lowes, Kym N., Murphy, James M., Gyrd-Hansen, Mads, Parker, Michael W., Hartland, Elizabeth L., Lew, Andrew M., Huang, David C. S., Lessene, Guillaume, Silke, John
Published in Nature communications (17.03.2015)
Published in Nature communications (17.03.2015)
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Journal Article
A regulatory region on RIPK2 is required for XIAP binding and NOD signaling activity
Heim, Valentin J, Dagley, Laura F, Stafford, Che A, Hansen, Fynn M, Clayer, Elise, Bankovacki, Aleksandra, Webb, Andrew I, Lucet, Isabelle S, Silke, John, Nachbur, Ueli
Published in EMBO reports (05.11.2020)
Published in EMBO reports (05.11.2020)
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Journal Article
A regulatory region on RIPK 2 is required for XIAP binding and NOD signaling activity
Heim, Valentin J, Dagley, Laura F, Stafford, Che A, Hansen, Fynn M, Clayer, Elise, Bankovacki, Aleksandra, Webb, Andrew I, Lucet, Isabelle S, Silke, John, Nachbur, Ueli
Published in EMBO reports (05.11.2020)
Published in EMBO reports (05.11.2020)
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Journal Article
Phosphoproteome profiling uncovers a key role for CDKs in TNF signaling
Tanzer, Maria C, Bludau, Isabell, Stafford, Che A, Hornung, Veit, Mann, Matthias
Published in bioRxiv (05.11.2020)
Published in bioRxiv (05.11.2020)
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Paper
Priming enables a NEK7-independent route of NLRP3 activation
Schmacke, Niklas A, Gaidt, Moritz M, Szymanska, Inga, O'duill, Fionan, Stafford, Che A, Chauhan, Dhruv, Froehlich, Adrian L, Nagl, Dennis, Pinci, Francesca, Schmid-Burgk, Jonathan L, Hornung, Veit
Published in bioRxiv (09.10.2019)
Published in bioRxiv (09.10.2019)
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Paper