Search Results - "St.-Onge, Stéphane" :: K.UTB vyhledávací portál | TBU Library Retrieval Portal

Effector membrane translocation biosensors reveal G protein and βarrestin coupling profiles of 100 therapeutically relevant GPCRs

Effector membrane translocation biosensors reveal G protein and βarrestin coupling profiles of 100 therapeutically relevant GPCRs

by Avet, Charlotte, Mancini, Arturo, Breton, Billy, Le Gouill, Christian, Hauser, Alexander S, Normand, Claire, Kobayashi, Hiroyuki, Gross, Florence, Hogue, Mireille, Lukasheva, Viktoriya, St-Onge, Stéphane, Carrier, Marilyn, Héroux, Madeleine, Morissette, Sandra, Fauman, Eric B, Fortin, Jean-Philippe, Schann, Stephan, Leroy, Xavier, Gloriam, David E, Bouvier, Michel
Published in eLife (18.03.2022)

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In Vitro and In Vivo Evaluation of a Small-Molecule APJ (Apelin Receptor) Agonist, BMS-986224, as a Potential Treatment for Heart Failure

In Vitro and In Vivo Evaluation of a Small-Molecule APJ (Apelin Receptor) Agonist, BMS-986224, as a Potential Treatment for Heart Failure

by Gargalovic, Peter, Wong, Pancras, Onorato, Joelle, Finlay, Heather, Wang, Tao, Yan, Mujing, Crain, Earl, St-Onge, Stéphane, Héroux, Madeleine, Bouvier, Michel, Xu, Carrie, Chen, Xue-Qing, Generaux, Claudia, Lawrence, Michael, Wexler, Ruth, Gordon, David
Published in Circulation. Heart failure (01.03.2021)

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Preservation of Post-Infarction Cardiac Structure and Function via Long-Term Oral Formyl Peptide Receptor Agonist Treatment

Preservation of Post-Infarction Cardiac Structure and Function via Long-Term Oral Formyl Peptide Receptor Agonist Treatment

by García, Ricardo A., Ito, Bruce R., Lupisella, John A., Carson, Nancy A., Hsu, Mei-Yin, Fernando, Gayani, Heroux, Madeleine, Bouvier, Michel, Dierks, Elizabeth, Kick, Ellen K., Gordon, David A., Chen, Jian, Mintier, Gabe, Carrier, Marilyn, St-Onge, Stéphane, Shah, Himanshu, Towne, Jordan, Bucardo, Marcela Sotelo, Ma, Xiuying, Ryan, Carol S., Wurtz, Nicholas R., Ostrowski, Jacek, Villarreal, Francisco J.
Published in JACC. Basic to translational science (01.12.2019)

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Selective FPR2 Agonism Promotes a Proresolution Macrophage Phenotype and Improves Cardiac Structure-Function Post Myocardial Infarction

Selective FPR2 Agonism Promotes a Proresolution Macrophage Phenotype and Improves Cardiac Structure-Function Post Myocardial Infarction

by García, Ricardo A., Lupisella, John A., Ito, Bruce R., Hsu, Mei-Yin, Fernando, Gayani, Carson, Nancy L., Allocco, John J., Ryan, Carol S., Zhang, Rongan, Wang, Zhaoqing, Heroux, Madeleine, Carrier, Marilyn, St.-Onge, Stéphane, Bouvier, Michel, Dudhgaonkar, Shailesh, Nagar, Jignesh, Bustamante-Pozo, Moises M., Garate-Carrillo, Alejandra, Chen, Jian, Ma, Xiuying, Search, Debra J., Dierks, Elizabeth A., Kick, Ellen K., Wexler, Ruth R., Gordon, David A., Ostrowski, Jacek, Wurtz, Nicholas R., Villarreal, Francisco
Published in JACC. Basic to translational science (01.08.2021)

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A peripherally restricted cannabinoid receptor agonist produces robust anti-nociceptive effects in rodent models of inflammatory and neuropathic pain

A peripherally restricted cannabinoid receptor agonist produces robust anti-nociceptive effects in rodent models of inflammatory and neuropathic pain

by Yu, Xiao Hong, Cao, Chang Qing, Martino, Giovanni, Puma, Carole, Morinville, Anne, St-Onge, Stéphane, Lessard, Étienne, Perkins, Martin N., Laird, Jennifer M.A.
Published in Pain (Amsterdam) (01.11.2010)

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Molecular Mechanisms of Desensitization Underlying the Differential Effects of Formyl Peptide Receptor 2 Agonists on Cardiac Structure–Function Post Myocardial Infarction

Molecular Mechanisms of Desensitization Underlying the Differential Effects of Formyl Peptide Receptor 2 Agonists on Cardiac Structure–Function Post Myocardial Infarction

by Lupisella, John, St-Onge, Stéphane, Carrier, Marilyn, Cook, Erica M., Wang, Tao, Sum, Chi, Fernando, Gayani, Apgar, Kendra, Zhang, Rongan, Carson, Nancy, Snyder, Bradley J., Ryan, Carol S., Ma, Xiuying, Dierks, Elizabeth A., Little, Sean, Kick, Ellen K., Wurtz, Nicholas R., Bouvier, Michel, Héroux, Madeleine, Garcia, Ricardo A.
Published in ACS pharmacology & translational science (14.10.2022)

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New 1,2,3,4-tetrahydropyrrolo[3,4- b]indole derivatives as selective CB2 receptor agonists

New 1,2,3,4-tetrahydropyrrolo[3,4- b]indole derivatives as selective CB2 receptor agonists

by Pagé, Daniel, Yang, Hua, Brown, William, Walpole, Christopher, Fleurent, Manon, Fyfe, Meredith, Gaudreault, François, St-Onge, Stéphane
Published in Bioorganic & medicinal chemistry (15.11.2007)

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Novel benzimidazole derivatives as selective CB2 agonists

Novel benzimidazole derivatives as selective CB2 agonists

by Pagé, Daniel, Balaux, Elise, Boisvert, Luc, Liu, Ziping, Milburn, Claire, Tremblay, Maxime, Wei, Zhongyong, Woo, Simon, Luo, Xuehong, Cheng, Yun-Xing, Yang, Hua, Srivastava, Sanjay, Zhou, Fei, Brown, William, Tomaszewski, Miroslaw, Walpole, Christopher, Hodzic, Leila, St-Onge, Stéphane, Godbout, Claude, Salois, Dominic, Payza, Keymal
Published in Bioorganic & medicinal chemistry (01.07.2008)

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Recovery of homogeneous and functional β2-adrenergic receptors from extracellular baculovirus particles

Recovery of homogeneous and functional β2-adrenergic receptors from extracellular baculovirus particles

by Loisel, Thomas P, Ansanay, Hervé, St-Onge, Stéphane, Gay, Bernard, Boulanger, Pierre, Strosberg, A. Donny, Marullo, Stefano, Bouvier, Michel
Published in Nature biotechnology (01.11.1997)

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The receptor for the orexigenic peptide melanin-concentrating hormone is a G-protein-coupled receptor

The receptor for the orexigenic peptide melanin-concentrating hormone is a G-protein-coupled receptor

by Ahmad, Sultan, Lembo, Paola M.C, Grazzini, Eric, Cao, Jack, Hubatsch, Douglas A, Pelletier, Manon, Hoffert, Cyrla, St-Onge, Stephane, Pou, Chantevy, Labrecque, Jean, Groblewski, Thierry, O'Donnell, Dajan, Payza, Kemal, Walker, Philippe
Published in Nature cell biology (01.09.1999)

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Effector membrane translocation biosensors reveal G protein and [beta]arrestin coupling profiles of 100 therapeutically relevant GPCRs

Effector membrane translocation biosensors reveal G protein and [beta]arrestin coupling profiles of 100 therapeutically relevant GPCRs

by Avet, Charlotte, Mancini, Arturo, Breton, Billy, Le Gouill, Christian, Hauser, Alexander S, Normand, Claire, Kobayashi, Hiroyuki, Gross, Florence, Hogue, Mireille, Lukasheva, Viktoriya, St-Onge, Stéphane, Carrier, Marilyn, Héroux, Madeleine, Morissette, Sandra, Fauman, Eric B, Fortin, Jean-Philippe, Schann, Stephan, Leroy, Xavier, Gloriam, David E, Bouvier, Michel
Published in eLife (18.03.2022)

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N-Methyl-3-(tetrahydro-2H-pyran-4-yl)-2,3,4,9-tetrahydro-1H-carbazole-6-carboxamides as a novel class of cannabinoid receptors agonists with low CNS penetration

N-Methyl-3-(tetrahydro-2H-pyran-4-yl)-2,3,4,9-tetrahydro-1H-carbazole-6-carboxamides as a novel class of cannabinoid receptors agonists with low CNS penetration

by Wei, Zhongyong, Yang, Hua, Liu, Ziping, Tremblay, Maxime, Johnstone, Shawn, Béha, Sara, Yue, Shi Yi, Srivastava, Sanjay, Tomaszewski, Miroslaw J., Brown, William, Walpole, Christopher, St-Onge, Stéphane, Lessard, Etienne, Archambault, Anne-Julie, Groblewski, Thierry, Pagé, Daniel
Published in Bioorganic & medicinal chemistry letters (15.06.2012)

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Functional rescue of a constitutively desensitized β2AR through receptor dimerization

Functional rescue of a constitutively desensitized β2AR through receptor dimerization

by HEBERT, E. Terence, LOISEL, P. Thomas, ADAM, Lynda, ETHIER, Nathalie, ONGE, ST. Stephane, BOUVIER, Michel
Published in Biochemical journal (15.02.1998)

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Discovery of Agonists of Cannabinoid Receptor 1 with Restricted Central Nervous System Penetration Aimed for Treatment of Gastroesophageal Reflux Disease

Discovery of Agonists of Cannabinoid Receptor 1 with Restricted Central Nervous System Penetration Aimed for Treatment of Gastroesophageal Reflux Disease

by Plowright, Alleyn T, Nilsson, Karolina, Antonsson, Madeleine, Amin, Kosrat, Broddefalk, Johan, Jensen, Jörgen, Lehmann, Anders, Jin, Shujuan, St-Onge, Stephane, Tomaszewski, Mirosław J, Tremblay, Maxime, Walpole, Christopher, Wei, Zhongyong, Yang, Hua, Ulander, Johan
Published in Journal of medicinal chemistry (10.01.2013)

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Corrigendum to “Novel benzimidazole derivatives as selective CB2 agonists” [Bioorg. Med. Chem. Lett. 18 (2008) 3695–3700]

Corrigendum to “Novel benzimidazole derivatives as selective CB2 agonists” [Bioorg. Med. Chem. Lett. 18 (2008) 3695–3700]

by Pagé, Daniel, Balaux, Elise, Boisvert, Luc, Liu, Ziping, Milburn, Claire, Tremblay, Maxime, Wei, Zhongyong, Woo, Simon, Luo, Xuehong, Cheng, Yun-Xing, Yang, Hua, Srivastava, Sanjay, Zhou, Fei, Brown, William, Tomaszewski, Miroslaw, Walpole, Christopher, Hodzic, Leila, St-Onge, Stéphane, Godbout, Claude, Salois, Dominic, Payza, Kemal
Published in Bioorganic & medicinal chemistry letters (01.09.2008)

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γ-Carbolines: A novel class of cannabinoid agonists with high aqueous solubility and restricted CNS penetration

γ-Carbolines: A novel class of cannabinoid agonists with high aqueous solubility and restricted CNS penetration

by Cheng, Yun-Xing, Pourashraf, Mehrnaz, Luo, Xuehong, Srivastava, Sanjay, Walpole, Christopher, Salois, Dominic, St-Onge, Stephane, Payza, Kemal, Lessard, Etienne, Yu, Xiao Hong, Tomaszewski, Mirosław J.
Published in Bioorganic & medicinal chemistry letters (15.02.2012)

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N-Methyl-3-(tetrahydro-2H-pyran-4-yl)-2,3,4,9-tetrahydro-1H-carbaz ole- 6-carboxamides as a novel class of cannabinoid receptors agonists with low CNS penetration

N-Methyl-3-(tetrahydro-2H-pyran-4-yl)-2,3,4,9-tetrahydro-1H-carbaz ole- 6-carboxamides as a novel class of cannabinoid receptors agonists with low CNS penetration

by Wei, Zhongyong, Yang, Hua, Liu, Ziping, Tremblay, Maxime, Johnstone, Shawn, Beha, Sara, Yue, Shi Yi, Srivastava, Sanjay, Tomaszewski, Miroslaw J, Brown, William, Walpole, Christopher, St-Onge, Stephane, Lessard, Etienne, Archambault, Anne-Julie, Groblewski, Thierry, Page, Daniel
Published in Bioorganic & medicinal chemistry letters (15.06.2012)

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N, N-Diethyl-4-[(3-hydroxyphenyl)(piperidin-4-yl)amino] benzamide derivatives: The development of diaryl amino piperidines as potent δ opioid receptor agonists with in vivo anti-nociceptive activity in rodent models

N, N-Diethyl-4-[(3-hydroxyphenyl)(piperidin-4-yl)amino] benzamide derivatives: The development of diaryl amino piperidines as potent δ opioid receptor agonists with in vivo anti-nociceptive activity in rodent models

by Jones, Paul, Griffin, Andrew M., Gawell, Lars, Lavoie, Rico, Delorme, Daniel, Roberts, Edward, Brown, William, Walpole, Christopher, Xiao, Wenhau, Boulet, Jamie, Labarre, Maryse, Coupal, Martin, Butterworth, Joanne, St-Onge, Stephane, Hodzic, Lejla, Salois, Dominic
Published in Bioorganic & medicinal chemistry letters (01.11.2009)

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Beta-adrenergic receptor desensitization in the early stage of hereditary cardiomyopathy in hamsters

Beta-adrenergic receptor desensitization in the early stage of hereditary cardiomyopathy in hamsters

by St-Onge, S, Chidiac, P, Brakier-Gingras, L, Bouvier, M
Published in Canadian journal of physiology and pharmacology (01.08.1994)

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Inverse agonism by Dmt–Tic analogues and HS 378, a naltrindole analogue

Inverse agonism by Dmt–Tic analogues and HS 378, a naltrindole analogue

by Labarre, Maryse, Butterworth, Joanne, St-Onge, Stephane, Payza, Kemal, Schmidhammer, Helmut, Salvadori, Severo, Balboni, Gianfranco, Guerrini, Remo, Bryant, Sharon D, Lazarus, Lawrence H
Published in European journal of pharmacology (06.10.2000)

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