Vupanorsen, an N-acetyl galactosamine-conjugated antisense drug to ANGPTL3 mRNA, lowers triglycerides and atherogenic lipoproteins in patients with diabetes, hepatic steatosis, and hypertriglyceridaemia
Gaudet, Daniel, Karwatowska-Prokopczuk, Ewa, Baum, Seth J, Hurh, Eunju, Kingsbury, Joyce, Bartlett, Victoria J, Figueroa, Amparo L, Piscitelli, Philip, Singleton, Walter, Witztum, Joseph L, Geary, Richard S, Tsimikas, Sotirios, O'Dea, Louis St. L
Published in European heart journal (21.10.2020)
Published in European heart journal (21.10.2020)
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Apolipoprotein C-III reduction in subjects with moderate hypertriglyceridaemia and at high cardiovascular risk
Tardif, Jean-Claude, Karwatowska-Prokopczuk, Ewa, Amour, Eric St, Ballantyne, Christie M, Shapiro, Michael D, Moriarty, Patrick M, Baum, Seth J, Hurh, Eunju, Bartlett, Victoria J, Kingsbury, Joyce, Figueroa, Amparo L, Alexander, Veronica J, Tami, Joseph, Witztum, Joseph L, Geary, Richard S, O’Dea, Louis St L, Tsimikas, Sotirios, Gaudet, Daniel
Published in European heart journal (06.04.2022)
Published in European heart journal (06.04.2022)
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Effects of Abaloparatide, a Human Parathyroid Hormone-Related Peptide Analog, on Bone Mineral Density in Postmenopausal Women with Osteoporosis
Leder, Benjamin Z, O'Dea, Louis St.L, Zanchetta, José R, Kumar, Prasana, Banks, Kathleen, McKay, Kathleen, Lyttle, C. Richard, Hattersley, Gary
Published in The journal of clinical endocrinology and metabolism (01.02.2015)
Published in The journal of clinical endocrinology and metabolism (01.02.2015)
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Design, Synthesis, and Preclinical Characterization of the Selective Androgen Receptor Modulator (SARM) RAD140
Miller, Chris P, Shomali, Maysoun, Lyttle, C. Richard, O’Dea, Louis St. L, Herendeen, Hillary, Gallacher, Kyla, Paquin, Dottie, Compton, Dennis R, Sahoo, Bishwabhusan, Kerrigan, Sean A, Burge, Matthew S, Nickels, Michael, Green, Jennifer L, Katzenellenbogen, John A, Tchesnokov, Alexei, Hattersley, Gary
Published in ACS medicinal chemistry letters (10.02.2011)
Published in ACS medicinal chemistry letters (10.02.2011)
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Recombinant human luteinizing hormone, lutropin alfa, for the induction of follicular development and pregnancy in profoundly gonadotrophin-deficient women
Kaufmann, Robert, Dunn, Randall, Vaughn, Thomas, Hughes, Graeme, O'Brien, Fanny, Hemsey, George, Thomson, Barbara, St. L. O'Dea, Louis
Published in Clinical endocrinology (Oxford) (01.10.2007)
Published in Clinical endocrinology (Oxford) (01.10.2007)
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Differentiating Familial Chylomicronemia Syndrome From Multifactorial Severe Hypertriglyceridemia by Clinical Profiles
O'Dea, Louis St L, MacDougall, James, Alexander, Veronica J, Digenio, Andres, Hubbard, Brant, Arca, Marcello, Moriarty, Patrick M, Kastelein, John J P, Bruckert, Eric, Soran, Handrean, Witztum, Joseph L, Hegele, Robert A, Gaudet, Daniel
Published in Journal of the Endocrine Society (01.12.2019)
Published in Journal of the Endocrine Society (01.12.2019)
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Efficacy and safety of volanesorsen in patients with multifactorial chylomicronaemia (COMPASS): a multicentre, double-blind, randomised, placebo-controlled, phase 3 trial
Gouni-Berthold, Ioanna, Alexander, Veronica J, Yang, Qingqing, Hurh, Eunju, Steinhagen-Thiessen, Elisabeth, Moriarty, Patrick M, Hughes, Stephen G, Gaudet, Daniel, Hegele, Robert A, O'Dea, Louis St L, Stroes, Erik S G, Tsimikas, Sotirios, Witztum, Joseph L, Agarwal, Abhay, Ballantyne, Christie, Baum, Seth, Bergeron, Jean, Bruckert, Eric, Burdick, Richard, Castro-Cabezas, Manuel, Cervi, Mark, Corder, Clinton, DuFour, Robert, Farrington, Cecil Murray, Francis, Gordon, Galitz, Lawrence, Hamstead, Steven, Hemphill, Linda, Huffman, Cynthia, Issa, Basil, Julius, Ulrich, Kane, John, Krempf, Michel, Martin, Steven, Powell, James, Shultzaberger, Richard, Thompson, Craig, Thompson-Hargrave, Letitia, Toth, Peter, Turner, Traci, Valero, Rene, Verges, Bruno, Visseren, Frank L J, Vyas, Pankaj, Yataco, Alberto
Published in The lancet. Diabetes & endocrinology (01.05.2021)
Published in The lancet. Diabetes & endocrinology (01.05.2021)
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Assessment of efficacy and safety of volanesorsen for treatment of metabolic complications in patients with familial partial lipodystrophy: Results of the BROADEN study: Volanesorsen in FPLD; The BROADEN Study
Oral, Elif A, Garg, Abhimanyu, Tami, Joseph, Huang, Eric A, O'Dea, Louis St L, Schmidt, Hartmut, Tiulpakov, Anatoly, Mertens, Ann, Alexander, Veronica J, Watts, Lynnetta, Hurh, Eunju, Witztum, Joseph L, Geary, Richard S, Tsimikas, Sotirios
Published in Journal of clinical lipidology (01.11.2022)
Published in Journal of clinical lipidology (01.11.2022)
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Design and Rationale of the Global Phase 3 NEURO-TTRansform Study of Antisense Oligonucleotide AKCEA-TTR-L Rx (ION-682884-CS3) in Hereditary Transthyretin-Mediated Amyloid Polyneuropathy
Coelho, Teresa, Ando, Yukio, Benson, Merrill D, Berk, John L, Waddington-Cruz, Márcia, Dyck, Peter J, Gillmore, Julian D, Khella, Sami L, Litchy, William J, Obici, Laura, Monteiro, Cecilia, Tai, Li-Jung, Viney, Nicholas J, Buchele, Gustavo, Brambatti, Michela, Jung, Shiangtung W, St L O'Dea, Louis, Tsimikas, Sotirios, Schneider, Eugene, Geary, Richard S, Monia, Brett P, Gertz, Morie
Published in Neurology and therapy (01.06.2021)
Published in Neurology and therapy (01.06.2021)
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Design and Rationale of the Global Phase 3 NEURO-TTRansform Study of Antisense Oligonucleotide AKCEA-TTR-LRx (ION-682884-CS3) in Hereditary Transthyretin-Mediated Amyloid Polyneuropathy
Coelho, Teresa, Ando, Yukio, Benson, Merrill D., Berk, John L., Waddington-Cruz, Márcia, Dyck, Peter J., Gillmore, Julian D., Khella, Sami L., Litchy, William J., Obici, Laura, Monteiro, Cecilia, Tai, Li-Jung, Viney, Nicholas J., Buchele, Gustavo, Brambatti, Michela, Jung, Shiangtung W., St. L. O’Dea, Louis, Tsimikas, Sotirios, Schneider, Eugene, Geary, Richard S., Monia, Brett P., Gertz, Morie
Published in Neurology and therapy (01.06.2021)
Published in Neurology and therapy (01.06.2021)
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Assessment of efficacy and safety of volanesorsen for treatment of metabolic complications in patients with familial partial lipodystrophy: Results of the BROADEN study
Oral, Elif A., Garg, Abhimanyu, Tami, Joseph, Huang, Eric A., O'Dea, Louis St.L., Schmidt, Hartmut, Tiulpakov, Anatoly, Mertens, Ann, Alexander, Veronica J., Watts, Lynnetta, Hurh, Eunju, Witztum, Joseph L., Geary, Richard S., Tsimikas, Sotirios
Published in Journal of clinical lipidology (01.11.2022)
Published in Journal of clinical lipidology (01.11.2022)
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Rationale and Design of a Phase 3 Study to Evaluate the Efficacy and Safety of ION-682884 in Patients with Transthyretin-Mediated Amyloid Cardiomyopathy (ATTR-CM)
Falk, Rodney H, Gertz, Morie A, Benson, Merrill D, Buchele, Gustavo, Brambatti, Michela, Tsimikas, Sotirios, Viney, Nicholas J, Tai, Li-Jung, Monteiro, Cecilia, Yang, Qingqing, O'Dea, Louis St L, Karwatowska-Prokopczuk, Ewa, Schneider, Eugene, Geary, Richard S, Monia, Brett P
Published in Blood (13.11.2019)
Published in Blood (13.11.2019)
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Revisiting Healthcare Workers as a Risk Group for Progression toward Tuberculosis/Reply
Olaru, Ioana D, Lange, Christoph, Sester, Martina, King, Thomas C, Upfal, Mark, O'Dea, Louis St L
Published in American journal of respiratory and critical care medicine (15.10.2015)
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Published in American journal of respiratory and critical care medicine (15.10.2015)
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Sex steroid control of gonadotropin secretion in the human male. I. Effects of testosterone administration in normal and gonadotropin-releasing hormone-deficient men
Finkelstein, J S, Whitcomb, R W, O'Dea, L S, Longcope, C, Schoenfeld, D A, Crowley, Jr, W F
Published in The journal of clinical endocrinology and metabolism (01.09.1991)
Published in The journal of clinical endocrinology and metabolism (01.09.1991)
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Sex steroid control of gonadotropin secretion in the human male. II. Effects of estradiol administration in normal and gonadotropin-releasing hormone-deficient men
Finkelstein, J S, O'Dea, L S, Whitcomb, R W, Crowley, Jr, W F
Published in The journal of clinical endocrinology and metabolism (01.09.1991)
Published in The journal of clinical endocrinology and metabolism (01.09.1991)
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Utility of free alpha-subunit as an alternative neuroendocrine marker of gonadotropin-releasing hormone (GnRH) stimulation of the gonadotroph in the human: evidence from normal and GnRH-deficient men
Whitcomb, R W, O'Dea, L S, Finkelstein, J S, Heavern, D M, Crowley, Jr, W F
Published in The journal of clinical endocrinology and metabolism (01.06.1990)
Published in The journal of clinical endocrinology and metabolism (01.06.1990)
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Pulsatile gonadotropin secretion after discontinuation of long term gonadotropin-releasing hormone (GnRH) administration in a subset of GnRH-deficient men
Finkelstein, J S, Spratt, D I, O'Dea, L S, Whitcomb, R W, Klibanski, A, Schoenfeld, D A, Crowley, Jr, W F
Published in The journal of clinical endocrinology and metabolism (01.08.1989)
Published in The journal of clinical endocrinology and metabolism (01.08.1989)
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