Smac mimetics synergize with immune checkpoint inhibitors to promote tumour immunity against glioblastoma
Beug, Shawn T., Beauregard, Caroline E., Healy, Cristin, Sanda, Tarun, St-Jean, Martine, Chabot, Janelle, Walker, Danielle E., Mohan, Aditya, Earl, Nathalie, Lun, Xueqing, Senger, Donna L., Robbins, Stephen M., Staeheli, Peter, Forsyth, Peter A., Alain, Tommy, LaCasse, Eric C., Korneluk, Robert G.
Published in Nature communications (15.02.2017)
Published in Nature communications (15.02.2017)
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Smac mimetics and innate immune stimuli synergize to promote tumor death
Beug, Shawn T, Tang, Vera A, LaCasse, Eric C, Cheung, Herman H, Beauregard, Caroline E, Brun, Jan, Nuyens, Jeffrey P, Earl, Nathalie, St-Jean, Martine, Holbrook, Janelle, Dastidar, Himika, Mahoney, Douglas J, Ilkow, Carolina, Le Boeuf, Fabrice, Bell, John C, Korneluk, Robert G
Published in Nature biotechnology (01.02.2014)
Published in Nature biotechnology (01.02.2014)
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LCL161 enhances expansion and survival of engineered anti-tumor T cells but is restricted by death signaling
Afsahi, Arya, Silvestri, Christopher M, Moore, Allyson E, Graham, Carly F, Bacchiochi, Kaylyn, St-Jean, Martine, Baker, Christopher L, Korneluk, Robert G, Beug, Shawn T, LaCasse, Eric C, Bramson, Jonathan L
Published in Frontiers in immunology (17.04.2023)
Published in Frontiers in immunology (17.04.2023)
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Targeted ablation of the cellular inhibitor of apoptosis 1 (cIAP1) attenuates denervation-induced skeletal muscle atrophy
Lala-Tabbert, Neena, Lejmi-Mrad, Rim, Timusk, Kristen, Fukano, Marina, Holbrook, Janelle, St-Jean, Martine, LaCasse, Eric C, Korneluk, Robert G
Published in Skeletal muscle (24.05.2019)
Published in Skeletal muscle (24.05.2019)
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Correction: Publisher Correction: Smac mimetics synergize with immune checkpoint inhibitors to promote tumour immunity against glioblastoma
Beug, Shawn T., Beauregard, Caroline E., Healy, Cristin, Sanda, Tarun, St-Jean, Martine, Chabot, Janelle, Walker, Danielle E., Mohan, Aditya, Earl, Nathalie, Lun, Xueqing, Senger, Donna L., Robbins, Stephen M., Staeheli, Peter, Forsyth, Peter A., Alain, Tommy, LaCasse, Eric C., Korneluk, Robert G.
Published in Nature communications (18.07.2018)
Published in Nature communications (18.07.2018)
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Combination of IAP Antagonists and TNF-α-Armed Oncolytic Viruses Induce Tumor Vascular Shutdown and Tumor Regression
Beug, Shawn T., Pichette, Stephanie J., St-Jean, Martine, Holbrook, Janelle, Walker, Danielle E., LaCasse, Eric C., Korneluk, Robert G.
Published in Molecular therapy. Oncolytics (28.09.2018)
Published in Molecular therapy. Oncolytics (28.09.2018)
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X-linked Inhibitor of Apoptosis Regulates T Cell Effector Function
Zehntner, Simone P, Bourbonniere, Lyne, Moore, Craig S, Morris, Stephen J, Methot, Danielle, St. Jean, Martine, Lacasse, Eric, Hebb, Andrea L. O, Robertson, George S, Durkin, Jon, Gillard, John W, Owens, Trevor
Published in The Journal of immunology (1950) (01.12.2007)
Published in The Journal of immunology (1950) (01.12.2007)
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The transcription factor SP3 drives TNF-α expression in response to Smac mimetics
Beug, Shawn T, Cheung, Herman H, Sanda, Tarun, St-Jean, Martine, Beauregard, Caroline E, Mamady, Hapsatou, Baird, Stephen D, LaCasse, Eric C, Korneluk, Robert G
Published in Science signaling (29.01.2019)
Published in Science signaling (29.01.2019)
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Loss of XIAP protein expression by RNAi and antisense approaches sensitizes cancer cells to functionally diverse chemotherapeutics
MCMANUS, Dan C, LEFEBVRE, Charles A, CHERTON-HORVAT, Gabriele, ST-JEAN, Martine, KANDIMALLA, Ekambar R, AGRAWAL, Sudhir, MORRIS, Stephen J, DURKIN, Jon P, LACASSE, Eric C
Published in Oncogene (21.10.2004)
Published in Oncogene (21.10.2004)
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Smac mimetics and innate immune stimuli synergize to promote tumor death: produced factors that led to cancer cell death in the presence of SMCs (Supplementary Fig. 17a). We also isolated primary macrophages from bone marrow and these macrophages also responded to oncolytic VSV infection in a dose-dependent manner to produce factors
Beug, Shawn T, Tang, Vera A, LaCasse, Eric C, Cheung, Herman H, Beauregard, Caroline E, Brun, Jan, Nuyens, Jeffrey P, Earl, Nathalie, St-Jean, Martine, Holbrook, Janelle, Dastidar, Himika, Mahoney, Douglas J, Ilkow, Carolina, Boeuf, Fabrice Le, Bell, John C, Korneluk, Robert G
Published in Nature biotechnology (01.02.2014)
Published in Nature biotechnology (01.02.2014)
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Publisher Correction: Smac mimetics synergize with immune checkpoint inhibitors to promote tumour immunity against glioblastoma
Beug, Shawn T, Beauregard, Caroline E, Healy, Cristin, Sanda, Tarun, St-Jean, Martine, Chabot, Janelle, Walker, Danielle E, Mohan, Aditya, Earl, Nathalie, Lun, Xueqing, Senger, Donna L, Robbins, Stephen M, Staeheli, Peter, Forsyth, Peter A, Alain, Tommy, LaCasse, Eric C, Korneluk, Robert G
Published in Nature communications (18.07.2018)
Published in Nature communications (18.07.2018)
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