A myelin-related transcriptomic profile is shared by Pitt–Hopkins syndrome models and human autism spectrum disorder
Phan, BaDoi N., Bohlen, Joseph F., Davis, Brittany A., Ye, Zengyou, Chen, Huei-Ying, Mayfield, Brent, Sripathy, Srinidhi Rao, Cerceo Page, Stephanie, Campbell, Morganne N., Smith, Hannah L., Gallop, Danisha, Kim, Hyojin, Thaxton, Courtney L., Simon, Jeremy M., Burke, Emily E., Shin, Joo Heon, Kennedy, Andrew J., Sweatt, J. David, Philpot, Benjamin D., Jaffe, Andrew E., Maher, Brady J.
Published in Nature neuroscience (01.03.2020)
Published in Nature neuroscience (01.03.2020)
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CaPTure: Calcium PeakToolbox for analysis of in vitro calcium imaging data
Tippani, Madhavi, Pattie, Elizabeth A, Davis, Brittany A, Nguyen, Claudia V, Wang, Yanhong, Sripathy, Srinidhi Rao, Maher, Brady J, Martinowich, Keri, Jaffe, Andrew E, Page, Stephanie Cerceo
Published in BMC neuroscience (30.11.2022)
Published in BMC neuroscience (30.11.2022)
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Evaluation of Nav1.8 as a therapeutic target for Pitt Hopkins Syndrome
Martinowich, Keri, Das, Debamitra, Sripathy, Srinidhi Rao, Mai, Yishan, Kenney, Rakaia F., Maher, Brady J.
Published in Molecular psychiatry (01.01.2023)
Published in Molecular psychiatry (01.01.2023)
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301. Pro-Myelinating Drugs Promote Functional Recovery in an ASD Mouse Model of Pitt-Hopkins Syndrome
Bohlen, Joseph, Cleary, Colin, Das, Debamitra, Sripathy, Srinidhi Rao, Sadowski, Norah, Shim, Gina, Kenney, Rakaia, Buchler, Ingrid, Banerji, Tapasree, Scanlan, Thomas, Mulkey, Daniel, Maher, Brady
Published in Biological psychiatry (1969) (01.05.2023)
Published in Biological psychiatry (1969) (01.05.2023)
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Promyelinating drugs promote functional recovery in an autism spectrum disorder mouse model of Pitt–Hopkins syndrome
Bohlen, Joseph F, Cleary, Colin M, Das, Debamitra, Sripathy, Srinidhi Rao, Sadowski, Norah, Shim, Gina, Kenney, Rakaia F, Buchler, Ingrid P, Banerji, Tapasree, Scanlan, Thomas S, Mulkey, Daniel K, Maher, Brady J
Published in Brain (London, England : 1878) (01.08.2023)
Published in Brain (London, England : 1878) (01.08.2023)
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Electrophysiological measures from human iPSC-derived neurons are associated with schizophrenia clinical status and predict individual cognitive performance
Page, Stephanie Cerceo, Sripathy, Srinidhi Rao, Farinelli, Federica, Ye, Zengyou, Wang, Yanhong, Hiler, Daniel J, Pattie, Elizabeth A, Nguyen, Claudia V, Tippani, Madhavi, Moses, Rebecca L, Chen, Huei-Ying, Tran, Matthew Nguyen, Eagles, Nicholas J, Stolz, Joshua M, Catallini, 2nd, Joseph L, Soudry, Olivia R, Dickinson, Dwight, Berman, Karen F, Apud, Jose A, Weinberger, Daniel R, Martinowich, Keri, Jaffe, Andrew E, Straub, Richard E, Maher, Brady J
Published in Proceedings of the National Academy of Sciences - PNAS (18.01.2022)
Published in Proceedings of the National Academy of Sciences - PNAS (18.01.2022)
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TCF4 Mutations Disrupt Synaptic Function Through Dysregulation of RIMBP2 in Patient-Derived Cortical Neurons
Davis, Brittany A., Chen, Huei-Ying, Ye, Zengyou, Ostlund, Isaac, Tippani, Madhavi, Das, Debamitra, Sripathy, Srinidhi Rao, Wang, Yanhong, Martin, Jacqueline M., Shim, Gina, Panchwagh, Neel M., Moses, Rebecca L., Farinelli, Federica, Bohlen, Joseph F., Li, Meijie, Luikart, Bryan W., Jaffe, Andrew E., Maher, Brady J.
Published in Biological psychiatry (1969) (01.04.2024)
Published in Biological psychiatry (1969) (01.04.2024)
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Psychiatric risk gene Transcription Factor 4 (TCF4) regulates the density and connectivity of distinct inhibitory interneuron subtypes
Chen, Huei-Ying, Phan, BaDoi N., Shim, Gina, Hamersky, Gregory R., Sadowski, Norah, O’Donnell, Thomas S., Sripathy, Srinidhi Rao, Bohlen, Joseph F., Pfenning, Andreas R., Maher, Brady J.
Published in Molecular psychiatry (01.11.2023)
Published in Molecular psychiatry (01.11.2023)
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Schizophrenia Risk Genes Converge into Shifting Co-Expression Networks Across Brain Development, Ageing and Brain Regions
Pergola, Giulio, Parihar, Madhur, Sportelli, Leonardo, Bharadwaj, Rahul, Radulescu, Eugenia, Blasi, Giuseppe, Chen, Qiang, Kleinman, Joel, Wang, Yanhong, Sripathy, Srinidhi Rao, Maher, Brady, Monaco, Alfonso, Shin, Joo Heon, Straub, Richard, Hyde, Thomas, Bertolino, Alessandro, Weinberger, Daniel
Published in Biological psychiatry (1969) (01.05.2022)
Published in Biological psychiatry (1969) (01.05.2022)
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302. Investigating the Impact of Common Genetic Risk Variants for Schizophrenia on Neuronal Function Elucidates Relationships Between Cellular Phenotypes, Clinical Status and Cognitive Performance
Sripathy, Srinidhi Rao, Page, Stephanie Cerceo, Farinelli, Federica, Ye, Zengyou, Wang, Yanhong, Das, Debamitra, Shim, Gina, Hiler, Daniel J., Pattie, Elizabeth A., Nguyen, Claudia V., Tippani, Madhavi, Chen, Huei-Ying, Tran, Matthew N., Eagles, Nicholas J., Stolz, Joshua M., Catallini, Joseph L., Soudry, Olivia R., Dickinson, Dwight, Weinberger, Daniel R., Martinowich, Keri, MacDonald, Matthew L., Shin, Joo Heon, Jaffe, Andrew E., Straub, Richard E., Maher, Brady J.
Published in Biological psychiatry (1969) (01.05.2023)
Published in Biological psychiatry (1969) (01.05.2023)
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Evaluation of Na v 1.8 as a therapeutic target for Pitt Hopkins Syndrome
Martinowich, Keri, Das, Debamitra, Sripathy, Srinidhi Rao, Mai, Yishan, Kenney, Rakaia F, Maher, Brady J
Published in Molecular psychiatry (01.01.2023)
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Published in Molecular psychiatry (01.01.2023)
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TH71. ELECTROPHYSIOLOGICAL MEASURES FROM HUMAN IPSC-DERIVED NEURONS ARE ASSOCIATED WITH SCHIZOPHRENIA CLINICAL STATUS AND PREDICT INDIVIDUAL COGNITIVE PERFORMANCE
Page, Stephanie Cerceo, Sripathy, Srinidhi Rao, Farinelli, Federica, Ye, Zengyou, Wang, Yanhong, Pattie, Elizabeth, Nguyen, Claudia, Tippani, Madhavi, Dickinson, Dwight, Berman, Karen, Weinberger, Daniel, Martinowich, Keri, Jaffe, Andrew, Straub, Richard, Maher, Brady
Published in European neuropsychopharmacology (01.10.2021)
Published in European neuropsychopharmacology (01.10.2021)
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Journal Article
TCF4 mutations disrupt synaptic function through dysregulation of RIMBP2 in patient-derived cortical neurons
Davis, Brittany A, Chen, Huei-Ying, Ye, Zengyou, Ostlund, Isaac, Tippani, Madhavi, Das, Debamitra, Srinidhi Rao Sripathy, Wang, Yanhong, Martin, Jacqueline M, Shim, Gina, Panchwagh, Neel M, Moses, Rebecca L, Farinelli, Federica, Bohlen, Joseph F, Li, Meijie, Luikart, Bryan W, Jaffe, Andrew E, Maher, Brady J
Published in bioRxiv (20.01.2023)
Published in bioRxiv (20.01.2023)
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Paper
A myelin-related transcriptomic profile is shared between Pitt Hopkins syndrome models and human autism spectrum disorder
Phan, BaDoi N., Bohlen, Joseph F., Davis, Brittany A., Ye, Zengyou, Chen, Huei-Ying, Mayfield, Brent, Sripathy, Srinidhi Rao, Page, Stephanie Cerceo, Campbell, Morganne N., Smith, Hannah L., Gallop, Danisha, Kim, Hyojin, Thaxton, Courtney L., Simon, Jeremy M., Burke, Emily E., Shin, Joo Heon, Kennedy, Andrew J., Sweatt, J. David, Philpot, Benjamin D., Jaffe, Andrew E., Maher, Brady J.
Published in Nature neuroscience (03.02.2020)
Published in Nature neuroscience (03.02.2020)
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Journal Article
Consensus molecular environment of schizophrenia risk genes in coexpression networks shifting across age and brain regions
Pergola, Giulio, Parihar, Madhur, Sportelli, Leonardo, Bharadwaj, Rahul, Borcuk, Christopher, Radulescu, Eugenia, Bellantuono, Loredana, Blasi, Giuseppe, Chen, Qiang, Kleinman, Joel E, Wang, Yanhong, Sripathy, Srinidhi Rao, Maher, Brady J, Monaco, Alfonso, Rossi, Fabiana, Shin, Joo Heon, Hyde, Thomas M, Bertolino, Alessandro, Weinberger, Daniel R
Published in Science advances (14.04.2023)
Published in Science advances (14.04.2023)
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Journal Article
Evaluation of Nav1.8 as a therapeutic target for Pitt Hopkins Syndrome
Martinowich, Keri, Das, Debamitra, Srinidhi Rao Sripathy, Maher, Brady J
Published in bioRxiv (16.04.2022)
Published in bioRxiv (16.04.2022)
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Paper
TCF4 mutations disrupt synaptic function through dysregulation of RIMBP2 in patient-derived cortical neurons
Davis, Brittany A, Chen, Huei-Ying, Ye, Zengyou, Ostlund, Isaac, Tippani, Madhavi, Das, Debamitra, Sripathy, Srinidhi Rao, Wang, Yanhong, Martin, Jacqueline M, Shim, Gina, Panchwagh, Neel M, Moses, Rebecca L, Farinelli, Federica, Bohlen, Joseph F, Li, Meijie, Luikart, Bryan W, Jaffe, Andrew E, Maher, Brady J
Published in bioRxiv : the preprint server for biology (20.01.2023)
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Published in bioRxiv : the preprint server for biology (20.01.2023)
Journal Article
Clemastine fumarate enhances myelination and promotes functional recovery in a syndromic ASD mouse model of Pitt-Hopkins Syndrome
Bohlen, Joseph F, Cleary, Colin M, Das, Debamitra, Srinidhi Rao Sripathy, Sadowski, Norah L, Shim, Gina, Kenney, Rakaia F, Buchler, Ingrid P, Mulkey, Daniel K, Maher, Brady J
Published in bioRxiv (04.05.2022)
Published in bioRxiv (04.05.2022)
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Paper
CaPTure: Calcium Peak Toolbox for analysis of in vitro calcium imaging data
Tippani, Madhavi, Pattie, Elizabeth A, Davis, Brittany A, Nguyen, Claudia V, Wang, Yanhong, Srinidhi Rao Sripathy, Maher, Brady J, Martinowich, Keri, Jaffe, Andrew E, Page, Stephanie Cerceo
Published in bioRxiv (09.09.2021)
Published in bioRxiv (09.09.2021)
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