Stabilizing the Hsp70-Tau Complex Promotes Turnover in Models of Tauopathy
Young, Zapporah T., Rauch, Jennifer N., Assimon, Victoria A., Jinwal, Umesh K., Ahn, Misol, Li, Xiaokai, Dunyak, Bryan M., Ahmad, Atta, Carlson, George A., Srinivasan, Sharan R., Zuiderweg, Erik R.P., Dickey, Chad A., Gestwicki, Jason E.
Published in Cell chemical biology (18.08.2016)
Published in Cell chemical biology (18.08.2016)
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Synthesis and Initial Evaluation of YM-08, a Blood-Brain Barrier Permeable Derivative of the Heat Shock Protein 70 (Hsp70) Inhibitor MKT-077, Which Reduces Tau Levels
Miyata, Yoshinari, Li, Xiaokai, Lee, Hsiu-Fang, Jinwal, Umesh K, Srinivasan, Sharan R, Seguin, Sandlin P, Young, Zapporah T, Brodsky, Jeffrey L, Dickey, Chad A, Sun, Duxin, Gestwicki, Jason E
Published in ACS chemical neuroscience (19.06.2013)
Published in ACS chemical neuroscience (19.06.2013)
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Discovery of Novel Activators of Large-Conductance Calcium-Activated Potassium Channels for the Treatment of Cerebellar Ataxia
Srinivasan, Sharan R, Huang, Haoran, Chang, Wei-Chih, Nasburg, Joshua A, Nguyen, Hai M, Strassmaier, Tim, Wulff, Heike, Shakkottai, Vikram G
Published in Molecular pharmacology (01.07.2022)
Published in Molecular pharmacology (01.07.2022)
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X-linked inhibitor of apoptosis protein (XIAP) is a client of heat shock protein 70 (Hsp70) and a biomarker of its inhibition
Cesa, Laura C., Shao, Hao, Srinivasan, Sharan R., Tse, Eric, Jain, Chetali, Zuiderweg, Erik R.P, Southworth, Daniel R., Mapp, Anna K., Gestwicki, Jason E.
Published in The Journal of biological chemistry (16.02.2018)
Published in The Journal of biological chemistry (16.02.2018)
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Heat Shock Protein 70 (Hsp70) Suppresses RIP1-Dependent Apoptotic and Necroptotic Cascades
Srinivasan, Sharan R, Cesa, Laura C, Li, Xiaokai, Julien, Olivier, Zhuang, Min, Shao, Hao, Chung, Jooho, Maillard, Ivan, Wells, James A, Duckett, Colin S, Gestwicki, Jason E
Published in Molecular cancer research (01.01.2018)
Published in Molecular cancer research (01.01.2018)
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Analogues of the Allosteric Heat Shock Protein 70 (Hsp70) Inhibitor, MKT-077, As Anti-Cancer Agents
Li, Xiaokai, Srinivasan, Sharan R, Connarn, Jamie, Ahmad, Atta, Young, Zapporah T, Kabza, Adam M, Zuiderweg, Erik. R. P, Sun, Duxin, Gestwicki, Jason E
Published in ACS medicinal chemistry letters (14.11.2013)
Published in ACS medicinal chemistry letters (14.11.2013)
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Clinical Trial-Ready Patient Cohorts for Multiple System Atrophy: Coupling Biospecimen and iPSC Banking to Longitudinal Deep-Phenotyping
Ndayisaba, Alain, Pitaro, Ariana T., Willett, Andrew S., Jones, Kristie A., de Gusmao, Claudio Melo, Olsen, Abby L., Kim, Jisoo, Rissanen, Eero, Woods, Jared K., Srinivasan, Sharan R., Nagy, Anna, Nagy, Amanda, Mesidor, Merlyne, Cicero, Steven, Patel, Viharkumar, Oakley, Derek H., Tuncali, Idil, Taglieri-Noble, Katherine, Clark, Emily C., Paulson, Jordan, Krolewski, Richard C., Ho, Gary P., Hung, Albert Y., Wills, Anne-Marie, Hayes, Michael T., Macmore, Jason P., Warren, Luigi, Bower, Pamela G., Langer, Carol B., Kellerman, Lawrence R., Humphreys, Christopher W., Glanz, Bonnie I., Dielubanza, Elodi J., Frosch, Matthew P., Freeman, Roy L., Gibbons, Christopher H., Stefanova, Nadia, Chitnis, Tanuja, Weiner, Howard L., Scherzer, Clemens R., Scholz, Sonja W., Vuzman, Dana, Cox, Laura M., Wenning, Gregor, Schmahmann, Jeremy D., Gupta, Anoopum S., Novak, Peter, Young, Geoffrey S., Feany, Mel B., Singhal, Tarun, Khurana, Vikram
Published in Cerebellum (London, England) (01.02.2024)
Published in Cerebellum (London, England) (01.02.2024)
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Correction to: Clinical trial-ready patient cohorts for multiple system atrophy: coupling biospecimen and iPSC banking to longitudinal deep-phenotyping
Ndayisaba, Alain, Pitaro, Ariana T., Willett, Andrew S., Jones, Kristie A., de Gusmao, Claudio Melo, Olsen, Abby L., Kim, Jisoo, Rissanen, Eero, Woods, Jared K., Srinivasan, Sharan R., Nagy, Anna, Nagy, Amanda, Mesidor, Merlyne, Cicero, Steven, Patel, Viharkumar, Oakley, Derek H., Tuncali, Idil, Taglieri-Noble, Katherine, Clark, Emily C., Paulson, Jordan, Krolewski, Richard C., Ho, Gary P., Hung, Albert Y., Wills, Anne-Marie, Hayes, Michael T., Macmore, Jason P., Warren, Luigi, Bower, Pamela G., Langer, Carol B., Kellerman, Lawrence R., Humphreys, Christopher W., Glanz, Bonnie I., Dielubanza, Elodi J., Frosch, Matthew P., Freeman, Roy L., Gibbons, Christopher H., Stefanova, Nadia, Chitnis, Tanuja, Weiner, Howard L., Scherzer, Clemens R., Scholz, Sonja W., Vuzman, Dana, Cox, Laura M., Wenning, Gregor, Schmahmann, Jeremy D., Gupta, Anoopum S., Novak, Peter, Young, Geoffrey S., Feany, Mel B., Singhal, Tarun, Khurana, Vikram
Published in Cerebellum (London, England) (01.02.2024)
Published in Cerebellum (London, England) (01.02.2024)
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Gerstmann-Sträussler-Scheinker Disease Presenting as Late-Onset Slowly Progressive Spinocerebellar Ataxia, and Comparative Case Series with Neuropathology
Stephen, Christopher D, de Gusmao, Claudio Melo, Srinivasan, Sharan R, Olsen, Abby, Freua, Fernando, Kok, Fernando, Montes Garcia Barbosa, Renata, Chen, Jin Yun Helen, Appleby, Brian S, Prior, Thomas, Frosch, Matthew P, Schmahmann, Jeremy D
Published in Movement disorders clinical practice (Hoboken, N.J.) (01.04.2024)
Published in Movement disorders clinical practice (Hoboken, N.J.) (01.04.2024)
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Fatigue Impacts Quality of Life in People with Spinocerebellar Ataxias
Lai, Ruo-Yah, Rummey, Christian, Amlang, Christian J, Lin, Chi-Ying R, Chen, Tiffany X, Perlman, Susan, Wilmot, George, Gomez, Christopher M, Schmahmann, Jeremy D, Paulson, Henry, Ying, Sarah H, Onyike, Chiadi U, Zesiewicz, Theresa A, Bushara, Khalaf O, Geschwind, Michael D, Figueroa, Karla P, Pulst, Stefan M, Subramony, Sub H, Burns, Matthew R, Opal, Puneet, Duquette, Antoine, Ashizawa, Tetsuo, Hamedani, Ali G, Davis, Marie Y, Srinivasan, Sharan R, Moore, Lauren R, Shakkottai, Vikram G, Rosenthal, Liana S, Kuo, Sheng-Han
Published in Movement disorders clinical practice (Hoboken, N.J.) (01.05.2024)
Published in Movement disorders clinical practice (Hoboken, N.J.) (01.05.2024)
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Molecular chaperones DnaK and DnaJ share predicted binding sites on most proteins in the E. coli proteomeElectronic supplementary information (ESI) available. See DOI: 10.1039/c2mb25145k
Srinivasan, Sharan R, Gillies, Anne T, Chang, Lyra, Thompson, Andrea D, Gestwicki, Jason E
Year of Publication 31.07.2012
Year of Publication 31.07.2012
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