Interaction between SNAI2 and MYOD enhances oncogenesis and suppresses differentiation in Fusion Negative Rhabdomyosarcoma
Pomella, Silvia, Sreenivas, Prethish, Gryder, Berkley E., Wang, Long, Milewski, David, Cassandri, Matteo, Baxi, Kunal, Hensch, Nicole R., Carcarino, Elena, Song, Young, Chou, Hsien-Chao, Yohe, Marielle E., Stanton, Benjamin Z., Amadio, Bruno, Caruana, Ignazio, De Stefanis, Cristiano, De Vito, Rita, Locatelli, Franco, Chen, Yidong, Chen, Eleanor Y., Houghton, Peter, Khan, Javed, Rota, Rossella, Ignatius, Myron S.
Published in Nature communications (08.01.2021)
Published in Nature communications (08.01.2021)
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Journal Article
Defining function of wild-type and three patient-specific TP53 mutations in a zebrafish model of embryonal rhabdomyosarcoma
Chen, Jiangfei, Baxi, Kunal, Lipsitt, Amanda E, Hensch, Nicole Rae, Wang, Long, Sreenivas, Prethish, Modi, Paulomi, Zhao, Xiang Ru, Baudin, Antoine, Robledo, Daniel G, Bandyopadhyay, Abhik, Sugalski, Aaron, Challa, Anil K, Kurmashev, Dias, Gilbert, Andrea R, Tomlinson, Gail E, Houghton, Peter, Chen, Yidong, Hayes, Madeline N, Chen, Eleanor Y, Libich, David S, Ignatius, Myron S
Published in eLife (02.06.2023)
Published in eLife (02.06.2023)
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MYOD-SKP2 axis boosts tumorigenesis in fusion negative rhabdomyosarcoma by preventing differentiation through p57Kip2 targeting
Pomella, Silvia, Cassandri, Matteo, D’Archivio, Lucrezia, Porrazzo, Antonella, Cossetti, Cristina, Phelps, Doris, Perrone, Clara, Pezzella, Michele, Cardinale, Antonella, Wachtel, Marco, Aloisi, Sara, Milewski, David, Colletti, Marta, Sreenivas, Prethish, Walters, Zoë S., Barillari, Giovanni, Di Giannatale, Angela, Milano, Giuseppe Maria, De Stefanis, Cristiano, Alaggio, Rita, Rodriguez-Rodriguez, Sonia, Carlesso, Nadia, Vakoc, Christopher R., Velardi, Enrico, Schafer, Beat W., Guccione, Ernesto, Gatz, Susanne A., Wasti, Ajla, Yohe, Marielle, Ignatius, Myron, Quintarelli, Concetta, Shipley, Janet, Miele, Lucio, Khan, Javed, Houghton, Peter J., Marampon, Francesco, Gryder, Berkley E., De Angelis, Biagio, Locatelli, Franco, Rota, Rossella
Published in Nature communications (15.12.2023)
Published in Nature communications (15.12.2023)
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MLL5, a trithorax homolog, indirectly regulates H3K4 methylation, represses cyclin A2 expression, and promotes myogenic differentiation
Sebastian, Soji, Sreenivas, Prethish, Sambasivan, Ramkumar, Cheedipudi, Sirisha, Kandalla, Prashanth, Pavlath, Grace K, Dhawan, Jyotsna
Published in Proceedings of the National Academy of Sciences - PNAS (24.03.2009)
Published in Proceedings of the National Academy of Sciences - PNAS (24.03.2009)
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Journal Article
The NOTCH1/SNAIL1/MEF2C Pathway Regulates Growth and Self-Renewal in Embryonal Rhabdomyosarcoma
Ignatius, Myron S., Hayes, Madeline N., Lobbardi, Riadh, Chen, Eleanor Y., McCarthy, Karin M., Sreenivas, Prethish, Motala, Zainab, Durbin, Adam D., Molodtsov, Aleksey, Reeder, Sophia, Jin, Alexander, Sindiri, Sivasish, Beleyea, Brian C., Bhere, Deepak, Alexander, Matthew S., Shah, Khalid, Keller, Charles, Linardic, Corinne M., Nielsen, Petur G., Malkin, David, Khan, Javed, Langenau, David M.
Published in Cell reports (Cambridge) (13.06.2017)
Published in Cell reports (Cambridge) (13.06.2017)
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Journal Article
Distinct transcriptional networks in quiescent myoblasts: a role for Wnt signaling in reversible vs. irreversible arrest
Subramaniam, Sindhu, Sreenivas, Prethish, Cheedipudi, Sirisha, Reddy, Vatrapu Rami, Shashidhara, Lingadahalli Subrahmanya, Chilukoti, Ravi Kumar, Mylavarapu, Madhavi, Dhawan, Jyotsna
Published in PloS one (03.06.2013)
Published in PloS one (03.06.2013)
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Journal Article
A fine balance: epigenetic control of cellular quiescence by the tumor suppressor PRDM2/RIZ at a bivalent domain in the cyclin a gene
Cheedipudi, Sirisha, Puri, Deepika, Saleh, Amena, Gala, Hardik P., Rumman, Mohammed, Pillai, Malini S., Sreenivas, Prethish, Arora, Reety, Sellathurai, Jeeva, Schrøder, Henrik Daa, Mishra, Rakesh K., Dhawan, Jyotsna
Published in Nucleic acids research (27.07.2015)
Published in Nucleic acids research (27.07.2015)
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Abstract 2863: CDKN1A prevents IR-induced apoptosis in rhabdomyosarcoma tumor via repressing the pro-apoptotic factor NOXA in a novel apoptotic regulatory axis
Modi, Paulomi S., Ignatius, Myron, Wang, Long, Sreenivas, Prethish
Published in Cancer research (Chicago, Ill.) (22.03.2024)
Published in Cancer research (Chicago, Ill.) (22.03.2024)
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Abstract 1465: A SNAI2/CDKN1A pathway protects rhabdomyosarcoma tumors from radiation
Modi, Paulomi S., Wang, Long, Sreenivas, Prethish, Ignatius, Myron
Published in Cancer research (Chicago, Ill.) (04.04.2023)
Published in Cancer research (Chicago, Ill.) (04.04.2023)
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Journal Article
Sensitization to Ionizing Radiation by MEK Inhibition Is Dependent on SNAI2 in Fusion-Negative Rhabdomyosarcoma
Hensch, Nicole R, Bondra, Kathryn, Wang, Long, Sreenivas, Prethish, Zhao, Xiang R, Modi, Paulomi, Vaseva, Angelina V, Houghton, Peter J, Ignatius, Myron S
Published in Molecular cancer therapeutics (03.01.2023)
Published in Molecular cancer therapeutics (03.01.2023)
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Journal Article
SNAI2-Mediated Repression of BIM Protects Rhabdomyosarcoma from Ionizing Radiation
Wang, Long, Hensch, Nicole R, Bondra, Kathryn, Sreenivas, Prethish, Zhao, Xiang R, Chen, Jiangfei, Moreno Campos, Rodrigo, Baxi, Kunal, Vaseva, Angelina V, Sunkel, Benjamin D, Gryder, Berkley E, Pomella, Silvia, Stanton, Benjamin Z, Zheng, Siyuan, Chen, Eleanor Y, Rota, Rossella, Khan, Javed, Houghton, Peter J, Ignatius, Myron S
Published in Cancer research (Chicago, Ill.) (01.11.2021)
Published in Cancer research (Chicago, Ill.) (01.11.2021)
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Journal Article
A SNAI2/CTCF Interaction is Required for NOTCH1 Expression in Rhabdomyosarcoma
Sreenivas, Prethish, Wang, Long, Wang, Meng, Challa, Anil, Modi, Paulomi, Hensch, Nicole Rae, Gryder, Berkley, Chou, Hsien-Chao, Zhao, Xiang R, Sunkel, Benjamin, Moreno-Campos, Rodrigo, Khan, Javed, Stanton, Benjamin Z, Ignatius, Myron S
Published in Molecular and cellular biology (2023)
Published in Molecular and cellular biology (2023)
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Journal Article
Abstract 3124: SNAI2 function in embryonal RMS
Pomelo, Silvia, Sreenivas, Prethish, Gryder, Berkley, Wang, Long, Kunal, Baxi, Hensch, Nicole, Chen, Eleanor, Houghton, Peter, Rota, Rossella, Khan, Javed, Ignatius, Myron S.
Published in Cancer research (Chicago, Ill.) (01.07.2019)
Published in Cancer research (Chicago, Ill.) (01.07.2019)
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Journal Article
The 3D chromatin landscape of rhabdomyosarcoma
Wang, Meng, Sreenivas, Prethish, Sunkel, Benjamin D, Wang, Long, Ignatius, Myron, Stanton, Benjamin Z
Published in NAR cancer (01.09.2023)
Published in NAR cancer (01.09.2023)
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Journal Article
A fine balance: epigenetic control of cellular quiescence by the tumor suppressor PRDM2/RIZ at a bivalent domain in the cyclin a gene
Cheedipudi, Sirisha, Puri, Deepika, Saleh, Amena, Gala, Hardik P, Rumman, Mohammed, Pillai, Malini S, Sreenivas, Prethish, Arora, Reety, Sellathurai, Jeeva, Schrøder, Henrik Daa, Mishra, Rakesh K, Dhawan, Jyotsna
Published in Nucleic acids research (27.07.2015)
Published in Nucleic acids research (27.07.2015)
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Journal Article
Abstract B35: Liaison between SNAI2 and MYOD enhances oncogenesis and suppresses differentiation in fusion-negative rhabdomyosarcoma
Pomella, Silvia, Sreenivas, Prethish, Gryder, Berkley E., Wang, Long, Cassandri, Matteo, Baxi, Kunal, Hensch, Nicole R., Carcarino, Elena, Song, Young, Yohe, Marielle, Amadio, Bruno, Caruana, Ignazio, De Stefanis, Cristiano, De Vito, Rita, Locatelli, Franco, Chen, Yidong, Chen, Eleanor Y., Houghton, Peter, Khan, Javed, Rota, Rossella, Ignatius, Myron S.
Published in Cancer research (Chicago, Ill.) (15.07.2020)
Published in Cancer research (Chicago, Ill.) (15.07.2020)
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Journal Article
Quercetin attenuates Monocyte Chemoattractant Protein-1 gene expression in glucose primed aortic endothelial cells through NF-κB and AP-1
Panicker, Sumith Retnamma, Sreenivas, Prethish, Babu, Mani Sankar, Karunagaran, Devarajan, Kartha, Chandrasekharan Cheranellore
Published in Pharmacological research (01.10.2010)
Published in Pharmacological research (01.10.2010)
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Journal Article
Ketogenic diet induces p53-dependent cellular senescence in multiple organs
Wei, Sung-Jen, Schell, Joseph R, Chocron, E Sandra, Varmazyad, Mahboubeh, Xu, Guogang, Chen, Wan Hsi, Martinez, Gloria M, Dong, Felix F, Sreenivas, Prethish, Trevino, Jr, Rolando, Jiang, Haiyan, Du, Yan, Saliba, Afaf, Qian, Wei, Lorenzana, Brandon, Nazarullah, Alia, Chang, Jenny, Sharma, Kumar, Munkácsy, Erin, Horikoshi, Nobuo, Gius, David
Published in Science advances (17.05.2024)
Published in Science advances (17.05.2024)
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Mitochondrial ACSS1-K635 acetylation knock-in mice exhibit altered metabolism, cell senescence, and nonalcoholic fatty liver disease
Xu, Guogang, Quan, Songhua, Schell, Joseph, Gao, Yucheng, Varmazyad, Mahboubeh, Sreenivas, Prethish, Cruz, Diego, Jiang, Haiyan, Pan, Meixia, Han, Xianlin, Palavicini, Juan Pablo, Zhao, Peng, Sun, Xiaoli, Marchant, Erik D, Rasmussen, Blake B, Li, Guannan, Katsumura, Sakie, Morita, Masahiro, Munkácsy, Erin, Horikoshi, Nobuo, Chocron, E Sandra, Gius, David
Published in Science advances (17.05.2024)
Published in Science advances (17.05.2024)
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Journal Article
MYOD-SKP2 axis boosts tumorigenesis in fusion negative rhabdomyosarcoma by preventing differentiation through p57 Kip2 targeting
Pomella, Silvia, Cassandri, Matteo, D'Archivio, Lucrezia, Porrazzo, Antonella, Cossetti, Cristina, Phelps, Doris, Perrone, Clara, Pezzella, Michele, Cardinale, Antonella, Wachtel, Marco, Aloisi, Sara, Milewski, David, Colletti, Marta, Sreenivas, Prethish, Walters, Zoë S, Barillari, Giovanni, Di Giannatale, Angela, Milano, Giuseppe Maria, De Stefanis, Cristiano, Alaggio, Rita, Rodriguez-Rodriguez, Sonia, Carlesso, Nadia, Vakoc, Christopher R, Velardi, Enrico, Schafer, Beat W, Guccione, Ernesto, Gatz, Susanne A, Wasti, Ajla, Yohe, Marielle, Ignatius, Myron, Quintarelli, Concetta, Shipley, Janet, Miele, Lucio, Khan, Javed, Houghton, Peter J, Marampon, Francesco, Gryder, Berkley E, De Angelis, Biagio, Locatelli, Franco, Rota, Rossella
Published in Nature communications (15.12.2023)
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Published in Nature communications (15.12.2023)
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