A comprehensive analysis of rare genetic variation in amyotrophic lateral sclerosis in the UK
Morgan, Sarah, Shatunov, Aleksey, Sproviero, William, Jones, Ashley R, Shoai, Maryam, Hughes, Deborah, Al Khleifat, Ahmad, Malaspina, Andrea, Morrison, Karen E, Shaw, Pamela J, Shaw, Christopher E, Sidle, Katie, Orrell, Richard W, Fratta, Pietro, Hardy, John, Pittman, Alan, Al-Chalabi, Ammar
Published in Brain (London, England : 1878) (01.06.2017)
Published in Brain (London, England : 1878) (01.06.2017)
Get full text
Journal Article
C9orf72 intermediate expansions of 24-30 repeats are associated with ALS
Iacoangeli, Alfredo, Al Khleifat, Ahmad, Jones, Ashley R, Sproviero, William, Shatunov, Aleksey, Opie-Martin, Sarah, Morrison, Karen E, Shaw, Pamela J, Shaw, Christopher E, Fogh, Isabella, Dobson, Richard J, Newhouse, Stephen J, Al-Chalabi, Ammar
Published in Acta neuropathologica communications (17.07.2019)
Published in Acta neuropathologica communications (17.07.2019)
Get full text
Journal Article
Investigation of next-generation sequencing technologies as a diagnostic tool for amyotrophic lateral sclerosis
Morgan, Sarah, Shoai, Maryam, Fratta, Pietro, Sidle, Katie, Orrell, Richard, Sweeney, Mary G, Shatunov, Aleksey, Sproviero, William, Jones, Ashley, Al-Chalabi, Ammar, Malaspina, Andrea, Houlden, Henry, Hardy, John, Pittman, Alan
Published in Neurobiology of aging (01.03.2015)
Published in Neurobiology of aging (01.03.2015)
Get full text
Journal Article
Ataxin-1 and ataxin-2 intermediate-length PolyQ expansions in amyotrophic lateral sclerosis
Conforti, Francesca L, Spataro, Rossella, Sproviero, William, Mazzei, Rosalucia, Cavalcanti, Francesca, Condino, Francesca, Simone, Isabella L, Logroscino, Giancarlo, Patitucci, Alessandra, Magariello, Angela, Muglia, Maria, Rodolico, Carmelo, Valentino, Paola, Bono, Francesco, Colletti, Tiziana, Monsurrò, Maria R, Gambardella, Antonio, La Bella, Vincenzo
Published in Neurology (11.12.2012)
Published in Neurology (11.12.2012)
Get more information
Journal Article
The relationship between isolated hypertension with brain volumes in UK Biobank
Newby, Danielle, Winchester, Laura, Sproviero, William, Fernandes, Marco, Ghose, Upamanyu, Lyall, Donald, Launer, Lenore J., Nevado‐Holgado, Alejo J.
Published in Brain and behavior (01.05.2022)
Published in Brain and behavior (01.05.2022)
Get full text
Journal Article
Comparative effect of metformin versus sulfonylureas with dementia and Parkinson’s disease risk in US patients over 50 with type 2 diabetes mellitus
Newby, Danielle, Linden, Andrew Brent, Fernandes, Marco, Molero, Yasmina, Winchester, Laura, Sproviero, William, Ghose, Upamanyu, Li, Qingqin S, Launer, Lenore J, Duijn, Cornelia M van, Nevado-Holgado, Alejo J
Published in BMJ open diabetes research & care (15.09.2022)
Published in BMJ open diabetes research & care (15.09.2022)
Get full text
Journal Article
FUS mutations in sporadic amyotrophic lateral sclerosis: Clinical and genetic analysis
Sproviero, William, La Bella, Vincenzo, Mazzei, Rosalucia, Valentino, Paola, Rodolico, Carmelo, Simone, Isabella Laura, Logroscino, Giancarlo, Ungaro, Carmine, Magariello, Angela, Patitucci, Alessandra, Tedeschi, Gioacchino, Spataro, Rossella, Condino, Francesca, Bono, Francesco, Citrigno, Luigi, Monsurrò, Maria Rosaria, Muglia, Maria, Gambardella, Antonio, Quattrone, Aldo, Conforti, Francesca Luisa
Published in Neurobiology of aging (01.04.2012)
Published in Neurobiology of aging (01.04.2012)
Get full text
Journal Article
The multistep hypothesis of ALS revisited: The role of genetic mutations
Chiò, Adriano, Mazzini, Letizia, D'Alfonso, Sandra, Corrado, Lucia, Canosa, Antonio, Moglia, Cristina, Manera, Umberto, Bersano, Enrica, Brunetti, Maura, Barberis, Marco, Veldink, Jan H, van den Berg, Leonard H, Pearce, Neil, Sproviero, William, McLaughlin, Russell, Vajda, Alice, Hardiman, Orla, Rooney, James, Mora, Gabriele, Calvo, Andrea, Al-Chalabi, Ammar
Published in Neurology (14.08.2018)
Published in Neurology (14.08.2018)
Get more information
Journal Article
High Blood Pressure and Risk of Dementia: A Two-Sample Mendelian Randomization Study in the UK Biobank
Sproviero, William, Winchester, Laura, Newby, Danielle, Fernandes, Marco, Shi, Liu, Goodday, Sarah M., Prats-Uribe, Albert, Alhambra, Daniel P., Buckley, Noel J., Nevado-Holgado, Alejo J.
Published in Biological psychiatry (1969) (15.04.2021)
Published in Biological psychiatry (1969) (15.04.2021)
Get full text
Journal Article
Interplay of Metabolome and Gut Microbiome in Individuals With Major Depressive Disorder vs Control Individuals
Amin, Najaf, Liu, Jun, Bonnechere, Bruno, MahmoudianDehkordi, Siamak, Arnold, Matthias, Batra, Richa, Chiou, Yu-Jie, Fernandes, Marco, Ikram, M Arfan, Kraaij, Robert, Krumsiek, Jan, Newby, Danielle, Nho, Kwangsik, Radjabzadeh, Djawad, Saykin, Andrew J, Shi, Liu, Sproviero, William, Winchester, Laura, Yang, Yang, Nevado-Holgado, Alejo J, Kastenmüller, Gabi, Kaddurah-Daouk, Rima, van Duijn, Cornelia M
Published in JAMA psychiatry (Chicago, Ill.) (01.06.2023)
Published in JAMA psychiatry (Chicago, Ill.) (01.06.2023)
Get more information
Journal Article
Detection of long repeat expansions from PCR-free whole-genome sequence data
Dolzhenko, Egor, van Vugt, Joke J F A, Shaw, Richard J, Bekritsky, Mitchell A, van Blitterswijk, Marka, Narzisi, Giuseppe, Ajay, Subramanian S, Rajan, Vani, Lajoie, Bryan R, Johnson, Nathan H, Kingsbury, Zoya, Humphray, Sean J, Schellevis, Raymond D, Brands, William J, Baker, Matt, Rademakers, Rosa, Kooyman, Maarten, Tazelaar, Gijs H P, van Es, Michael A, McLaughlin, Russell, Sproviero, William, Shatunov, Aleksey, Jones, Ashley, Al Khleifat, Ahmad, Pittman, Alan, Morgan, Sarah, Hardiman, Orla, Al-Chalabi, Ammar, Shaw, Chris, Smith, Bradley, Neo, Edmund J, Morrison, Karen, Shaw, Pamela J, Reeves, Catherine, Winterkorn, Lara, Wexler, Nancy S, Housman, David E, Ng, Christopher W, Li, Alina L, Taft, Ryan J, van den Berg, Leonard H, Bentley, David R, Veldink, Jan H, Eberle, Michael A
Published in Genome research (01.11.2017)
Published in Genome research (01.11.2017)
Get full text
Journal Article
Association between centrally active angiotensin‐converting enzyme inhibitors with dementia risk
Newby, Danielle, Winchester, Laura M, Sproviero, William, Fernandes, Marco, Ghose, Upamanyu, Launer, Lenore J., Nevado‐Holgado, Alejo J
Published in Alzheimer's & dementia (01.06.2023)
Published in Alzheimer's & dementia (01.06.2023)
Get full text
Journal Article
Project MinE: study design and pilot analyses of a large-scale whole-genome sequencing study in amyotrophic lateral sclerosis
Wouter Van Rheenen, Pulit, Sara L, Dekker, Annelot M, Ahmad Al Khleifat, Brands, William J, Iacoangeli, Alfredo, Kenna, Kevin P, Kavak, Ersen, Kooyman, Maarten, McLaughlin, Russell L, Middelkoop, Bas, Moisse, Matthieu, Schellevis, Raymond D, Shatunov, Aleksey, Sproviero, William, Tazelaar, Gijs H P, Rick A A Van der Spek, Perry T C Van Doormaal, Van Eijk, Kristel R, Joke Van Vugt, Basak, A Nazli, Blair, Ian P, Glass, Jonathan D, Hardiman, Orla, Hide, Winston, Landers, John E, Mora, Jesus S, Morrison, Karen E, Newhouse, Stephen, Robberecht, Wim, Shaw, Christopher E, Shaw, Pamela J, Philip Van Damme, Van Es, Michael A, Wray, Naomi R, Al-Chalabi, Ammar, Leonard H Van den Berg, Veldink, Jan H
Published in European journal of human genetics : EJHG (01.10.2018)
Published in European journal of human genetics : EJHG (01.10.2018)
Get full text
Journal Article
Associations Between Brain Volumes and Cognitive Tests with Hypertensive Burden in UK Biobank
Newby, Danielle, Winchester, Laura, Sproviero, William, Fernandes, Marco, Wang, Dai, Kormilitzin, Andrey, Launer, Lenore J., Nevado-Holgado, Alejo J.
Published in Journal of Alzheimer's disease (01.01.2021)
Published in Journal of Alzheimer's disease (01.01.2021)
Get full text
Journal Article
ATXN2 Trinucleotide Repeat Length Correlates with Risk of ALS
Sproviero, William, Shatunov, Aleksey, Stahl, Daniel, Shoai, Maryam, van Rheenen, Wouter, Jones, Ashley R, Al-Sarraj, Safa, Andersen, Peter M, Bonini, Nancy M, Conforti, Francesca L, Van Damme, Philip, Daoud, Hussein, Del Mar Amador, Maria, Fogh, Isabella, Forzan, Monica, Gaastra, Ben, Gellera, Cinzia, Gitler, Aaron D, Hardy, John, Fratta, Pietro, La Bella, Vincenzo, Le Ber, Isabelle, Van Langenhove, Tim, Lattante, Serena, Lee, Yi-Chung, Malaspina, Andrea, Meininger, Vincent, Millecamps, Stèphanie, Orrell, Richard, Rademakers, Rosa, Robberecht, Wim, Rouleau, Guy, Ross, Owen A, Salachas, Francois, Sidle, Katie, Smith, Bradley N, Soong, Bing-Wen, Sorarù, Gianni, Stevanin, Giovanni, Kabashi, Edor, Troakes, Claire, van Broeckhoven, Christine, Veldink, Jan H, van den Berg, Leonard H, Shaw, Christopher E, Powell, John F, Al-Chalabi, Ammar
Published in Neurobiology of aging (01.03.2017)
Published in Neurobiology of aging (01.03.2017)
Get full text
Journal Article
Teaching old drugs new tricks: Do cardiovascular medications effect cognitive decline?: Epidemiology / Risk and protective factors in MCI and dementia
Newby, Danielle, Winchester, Laura, Sproviero, William, Fernandes, Marco, Launer, Lenore J., Lovestone, Simon, Nevado‐Holgado, Alejo J
Published in Alzheimer's & dementia (01.12.2020)
Published in Alzheimer's & dementia (01.12.2020)
Get full text
Journal Article
Teaching old drugs new tricks: Do cardiovascular medications effect cognitive decline?
Newby, Danielle, Winchester, Laura, Sproviero, William, Fernandes, Marco, Launer, Lenore J., Lovestone, Simon, Nevado‐Holgado, Alejo J
Published in Alzheimer's & dementia (01.12.2020)
Published in Alzheimer's & dementia (01.12.2020)
Get full text
Journal Article
The association between isolated hypertension and brain volumes in UK Biobank
Newby, Danielle, Winchester, Laura M, Sproviero, William, Fernandes, Marco, Ghose, Upamanyu, Li, Qingqin S, Launer, Lenore J, Nevado‐Holgado, Alejo J
Published in Alzheimer's & dementia (01.12.2021)
Published in Alzheimer's & dementia (01.12.2021)
Get full text
Journal Article
Genome-wide Meta-analysis Finds the ACSL5-ZDHHC6 Locus Is Associated with ALS and Links Weight Loss to the Disease Genetics
Iacoangeli, Alfredo, Lin, Tian, Al Khleifat, Ahmad, Jones, Ashley R., Opie-Martin, Sarah, Coleman, Jonathan R.I., Shatunov, Aleksey, Sproviero, William, Williams, Kelly L., Garton, Fleur, Restuadi, Restuadi, Henders, Anjali K., Mather, Karen A., Needham, Merilee, Mathers, Susan, Nicholson, Garth A., Rowe, Dominic B., Henderson, Robert, McCombe, Pamela A., Pamphlett, Roger, Blair, Ian P., Schultz, David, Sachdev, Perminder S., Newhouse, Stephen J., Proitsi, Petroula, Fogh, Isabella, Ngo, Shyuan T., Dobson, Richard J.B., Wray, Naomi R., Steyn, Frederik J., Al-Chalabi, Ammar
Published in Cell reports (Cambridge) (27.10.2020)
Published in Cell reports (Cambridge) (27.10.2020)
Get full text
Journal Article