Genetic and pharmacological modifications of thrombin formation in apolipoprotein e-deficient mice determine atherosclerosis severity and atherothrombosis onset in a neutrophil-dependent manner
Borissoff, Julian I, Otten, Jeroen J T, Heeneman, Sylvia, Leenders, Peter, van Oerle, René, Soehnlein, Oliver, Loubele, Sarah T B G, Hamulyák, Karly, Hackeng, Tilman M, Daemen, Mat J A P, Degen, Jay L, Weiler, Hartmut, Esmon, Charles T, van Ryn, Joanne, Biessen, Erik A L, Spronk, Henri M H, ten Cate, Hugo
Published in PloS one (07.02.2013)
Published in PloS one (07.02.2013)
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Factor XIa and Thrombin Generation Are Elevated in Patients with Acute Coronary Syndrome and Predict Recurrent Cardiovascular Events
Loeffen, Rinske, van Oerle, René, Leers, Mathie P G, Kragten, Johannes A, Crijns, Harry, Spronk, Henri M H, Ten Cate, Hugo
Published in PloS one (15.07.2016)
Published in PloS one (15.07.2016)
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Targeting Coagulation Factor Xa Promotes Regression of Advanced Atherosclerosis in Apolipoprotein-E Deficient Mice
Posthuma, Jelle J., Posma, Jens J. N., van Oerle, Rene, Leenders, Peter, van Gorp, Rick H., Jaminon, Armand M. G., Mackman, Nigel, Heitmeier, Stefan, Schurgers, Leon J., ten Cate, Hugo, Spronk, Henri M. H.
Published in Scientific reports (07.03.2019)
Published in Scientific reports (07.03.2019)
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Prothrombin complex concentrates and a specific antidote to dabigatran are effective ex-vivo in reversing the effects of dabigatran in an anticoagulation/liver trauma experimental model
Grottke, Oliver, van Ryn, Joanne, Spronk, Henri M H, Rossaint, Rolf
Published in Critical care (London, England) (05.02.2014)
Published in Critical care (London, England) (05.02.2014)
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Regression of warfarin-induced medial elastocalcinosis by high intake of vitamin K in rats
Schurgers, Leon J., Spronk, Henri M.H., Soute, Berry A.M., Schiffers, Paul M., DeMey, Jo G.R., Vermeer, Cees
Published in Blood (01.04.2007)
Published in Blood (01.04.2007)
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Composition of PM affects acute vascular inflammatory and coagulative markers - the RAPTES project
Strak, Maciej, Hoek, Gerard, Godri, Krystal J, Gosens, Ilse, Mudway, Ian S, van Oerle, René, Spronk, Henri M H, Cassee, Flemming R, Lebret, Erik, Kelly, Frank J, Harrison, Roy M, Brunekreef, Bert, Steenhof, Maaike, Janssen, Nicole A H
Published in PloS one (13.03.2013)
Published in PloS one (13.03.2013)
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Thrombin generation capacity of prothrombin complex concentrate in an in vitro dilutional model
Grottke, Oliver, Rossaint, Rolf, Henskens, Yvonne, van Oerle, Rene, Ten Cate, Hugo, Spronk, Henri M H
Published in PloS one (17.05.2013)
Published in PloS one (17.05.2013)
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Integrating Mechanisms in Thrombotic Peripheral Arterial Disease
Nagy, Magdolna, van der Meijden, Paola E. J, Glunz, Julia, Schurgers, Leon, Lutgens, Esther, ten Cate, Hugo, Heitmeier, Stefan, Spronk, Henri M. H
Published in Pharmaceuticals (Basel, Switzerland) (01.11.2022)
Published in Pharmaceuticals (Basel, Switzerland) (01.11.2022)
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Volume replacement strategies do not impair the binding of dabigatran to idarucizumab: Porcine model of hemodilution
Grottke, Oliver, van Ryn, Joanne, Zentai, Christian, Gan, Guanfa, Honickel, Markus, Rossaint, Rolf, Ten Cate, Hugo, Spronk, Henri M H
Published in PloS one (07.01.2019)
Published in PloS one (07.01.2019)
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Thrombin generation in the Glasgow Myocardial Infarction Study
Smid, Machiel, Dielis, Arne W J H, Spronk, Henri M H, Rumley, Ann, van Oerle, Rene, Woodward, Mark, ten Cate, Hugo, Lowe, Gordon
Published in PloS one (24.06.2013)
Published in PloS one (24.06.2013)
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Evaluation of the analytical performance of the PC100 platelet counter
Nagy, Magdolna, Fazaeli, Sepanta, van Oerle, René, Ten Cate, Hugo, Schemmann, Marcel, Sherry, John, Kelleher, Gillian, Spronk, Henri M H
Published in Thrombosis journal (04.05.2021)
Published in Thrombosis journal (04.05.2021)
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Relationships between coagulation factors and thrombin generation in a general population with arterial and venous disease background
van Paridon, Pauline C S, Panova-Noeva, Marina, van Oerle, Rene, Schulz, Andreas, Prochaska, Jürgen H, Arnold, Natalie, Schmidtmann, Irene, Beutel, Manfred, Pfeiffer, Norbert, Münzel, Thomas, Lackner, Karl J, Ten Cate, Hugo, Wild, Philipp S, Spronk, Henri M H
Published in Thrombosis journal (08.06.2022)
Published in Thrombosis journal (08.06.2022)
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Recombinant Factor VIIa Reduces Bleeding after Blunt Liver Injury in a Pig Model of Dilutional Coagulopathy under Severe Hypothermia
Spronk, Henri M H, Braunschweig, Till, Rossaint, Rolf, Wüst, Dirk C, van Oerle, Rene, Lauritzen, Brian, Tolba, Rene, Grottke, Oliver
Published in PloS one (22.06.2015)
Published in PloS one (22.06.2015)
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Higher levels of circulating desphospho-uncarboxylated matrix Gla protein over time are associated with worse survival: the prospective Maastricht Intensive Care COVID cohort
Mulder, Mark M G, Schellens, Joep, Sels, Jan-Willem E M, van Rosmalen, Frank, Hulshof, Anne-Marije, de Vries, Femke, Segers, Ruud, Mihl, Casper, van Mook, Walther N K A, Bast, Aalt, Spronk, Henri M H, Henskens, Yvonne M C, van der Horst, Iwan C C, Cate, Hugo Ten, Schurgers, Leon J, Drent, Marjolein, van Bussel, Bas C T
Published in Journal of intensive care (18.12.2023)
Published in Journal of intensive care (18.12.2023)
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Monitoring thrombin generation: is addition of corn trypsin inhibitor needed?
Spronk, Henri M H, Dielis, Arne W J H, Panova-Noeva, Marina, van Oerle, René, Govers-Riemslag, José W P, Hamulyák, Karly, Falanga, Anna, Cate, Hugo Ten
Published in Thrombosis and haemostasis (01.06.2009)
Published in Thrombosis and haemostasis (01.06.2009)
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Protein C or Protein S deficiency associates with paradoxically impaired platelet‐dependent thrombus and fibrin formation under flow
Brouns, Sanne L.N., Tullemans, Bibian M.E., Bulato, Cristiana, Perrella, Gina, Campello, Elena, Spiezia, Luca, van Geffen, Johanna P., Kuijpers, Marijke J.E., van Oerle, René, Spronk, Henri M.H., van der Meijden, Paola E.J., Simioni, Paolo, Heemskerk, Johan W.M.
Published in Research and practice in thrombosis and haemostasis (01.02.2022)
Published in Research and practice in thrombosis and haemostasis (01.02.2022)
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Thrombin generation and atherosclerosis
Kalz, Jana, ten Cate, Hugo, Spronk, Henri M. H.
Published in Journal of thrombosis and thrombolysis (2014)
Published in Journal of thrombosis and thrombolysis (2014)
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Increasing concentrations of prothrombin complex concentrate induce disseminated intravascular coagulation in a pig model of coagulopathy with blunt liver injury
Grottke, Oliver, Braunschweig, Till, Spronk, Henri M.H., Esch, Stephanie, Rieg, Annette D., van Oerle, Rene, ten Cate, Hugo, Fitzner, Christina, Tolba, Rene, Rossaint, Rolf
Published in Blood (18.08.2011)
Published in Blood (18.08.2011)
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