Gene Editing of CCR5 in Autologous CD4 T Cells of Persons Infected with HIV
Tebas, Pablo, Stein, David, Tang, Winson W, Frank, Ian, Wang, Shelley Q, Lee, Gary, Spratt, S. Kaye, Surosky, Richard T, Giedlin, Martin A, Nichol, Geoff, Holmes, Michael C, Gregory, Philip D, Ando, Dale G, Kalos, Michael, Collman, Ronald G, Binder-Scholl, Gwendolyn, Plesa, Gabriela, Hwang, Wei-Ting, Levine, Bruce L, June, Carl H
Published in The New England journal of medicine (06.03.2014)
Published in The New England journal of medicine (06.03.2014)
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Delayed administration of a bio-engineered zinc-finger VEGF-A gene therapy is neuroprotective and attenuates allodynia following traumatic spinal cord injury
Figley, Sarah A, Liu, Yang, Karadimas, Spyridon K, Satkunendrarajah, Kajana, Fettes, Peter, Spratt, S Kaye, Lee, Gary, Ando, Dale, Surosky, Richard, Giedlin, Martin, Fehlings, Michael G
Published in PloS one (20.05.2014)
Published in PloS one (20.05.2014)
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Treatment of traumatic brain injury using zinc-finger protein gene therapy targeting VEGF-A
Siddiq, Ishita, Park, Eugene, Liu, Elaine, Spratt, S Kaye, Surosky, Richard, Lee, Gary, Ando, Dale, Giedlin, Marty, Hare, Gregory M T, Fehlings, Michael G, Baker, Andrew J
Published in Journal of neurotrauma (20.11.2012)
Published in Journal of neurotrauma (20.11.2012)
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Induction of angiogenesis in a mouse model using engineered transcription factors
Giordano, Frank J, Rebar, Edward J, Huang, Yan, Hickey, Reed, Nath, Anjali K, Meoli, David, Nath, Sameer, Chen, Bingliang, Xu, Lei, Liang, Yuxin, Jamieson, Andrew C, Zhang, Lei, Spratt, S Kaye, Case, Casey C, Wolffe, Alan
Published in Nature medicine (01.12.2002)
Published in Nature medicine (01.12.2002)
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A Designed Zinc-finger Transcriptional Repressor of Phospholamban Improves Function of the Failing Heart
Zhang, H Steve, Liu, Dingang, Huang, Yan, Schmidt, Stefan, Hickey, Reed, Guschin, Dmitry, Su, Haili, Jovin, Ion S, Kunis, Mike, Hinkley, Sarah, Liang, Yuxin, Hinh, Linda, Spratt, S Kaye, Case, Casey C, Rebar, Edward J, Ehrlich, Barbara, Gregory, Philip D, Giordano, Frank J
Published in Molecular therapy (01.08.2012)
Published in Molecular therapy (01.08.2012)
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Gene Transfer of an Engineered Transcription Factor Promoting Expression of VEGF-A Protects Against Experimental Diabetic Neuropathy
PRICE, Sally A, DENT, Carolyn, TOMLINSON, David R, DURAN-JIMENEZ, Beatriz, YUXIN LIANG, LEI ZHANG, REBAR, Edward J, CASE, Casey C, GREGORY, Philip D, MARTIN, Tyler J, KAYE SPRATT, S
Published in Diabetes (New York, N.Y.) (01.06.2006)
Published in Diabetes (New York, N.Y.) (01.06.2006)
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Zinc-Finger Protein-Targeted Gene Regulation: Genomewide Single-Gene Specificity
Tan, Siyuan, Guschin, Dmitry, Davalos, Albert, Lee, Ya-Li, Snowden, Andrew W., Jouvenot, Yann, Zhang, H. Steven, Howes, Katherine, McNamara, Andrew R., Lai, Albert, Ullman, Chris, Reynolds, Lindsey, Moore, Michael, Isalan, Mark, Berg, Lutz-Peter, Campos, Bradley, Qi, Hong, Spratt, S. Kaye, Case, Casey C., Pabo, Carl O., Campisi, Judith, Gregory, Philip D.
Published in Proceedings of the National Academy of Sciences - PNAS (14.10.2003)
Published in Proceedings of the National Academy of Sciences - PNAS (14.10.2003)
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Engineered Zinc Finger Protein–Mediated VEGF-A Activation Restores Deficient VEGF-A in Sensory Neurons in Experimental Diabetes
PAWSON, Elizabeth J, DURAN-JIMENEZ, Beatriz, SUROSKY, Richard, BROOKE, Heather E, SPRATT, S. Kaye, TOMLINSON, David R, GARDINER, Natalie J
Published in Diabetes (New York, N.Y.) (01.02.2010)
Published in Diabetes (New York, N.Y.) (01.02.2010)
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ZFN-Mediated Gene Targeting at the Albumin Locus in Liver Results in Therapeutic Levels of Human FIX in Mice and Non-Human Primates
Wechsler, Thomas, Meyer, Kathleen E., Spratt, S. Kaye, Greengard, Judith, Santiago, Yolanda, Sproul, Scott, Surosky, Richard, Paschon, David E., Dubois-Stringfellow, Nathalie, Ando, Dale Genji, Nichol, Geoff, Rebar, Edward J., Holmes, Michael C.
Published in Blood (03.12.2015)
Published in Blood (03.12.2015)
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Efficient clinical scale gene modification via zinc finger nuclease-targeted disruption of the HIV co-receptor CCR5
Maier, Dawn A, Brennan, Andrea L, Jiang, Shuguang, Binder-Scholl, Gwendolyn K, Lee, Gary, Plesa, Gabriela, Zheng, Zhaohui, Cotte, Julio, Carpenito, Carmine, Wood, Travis, Spratt, S Kaye, Ando, Dale, Gregory, Philip, Holmes, Michael C, Perez, Elena E, Riley, James L, Carroll, Richard G, June, Carl H, Levine, Bruce L
Published in Human gene therapy (01.03.2013)
Published in Human gene therapy (01.03.2013)
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Persistent and therapeutic concentrations of human factor IX in mice after hepatic gene transfer of recombinant AAV vectors
Snyder, Richard O, Miao, Carol H, Patijn, Gijsbert A, Spratt, S. Kaye, Danos, Olivier, Nagy, Dea, Gown, Allen M, Winther, Brian, Meuse, Leonard, Cohen, Lawrence K, Thompson, Arthur R, Kay, Mark A
Published in Nature genetics (01.07.1997)
Published in Nature genetics (01.07.1997)
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Prolonged Production of NADPH Oxidase-Corrected Granulocytes after Gene Therapy of Chronic Granulomatous Disease
Malech, H L, Maples, P B, Whiting-Theobald, N, Linton, G F, Sekhsaria, S, Vowells, S J, Li, F, Miller, J A, DeCarlo, E, Holland, S M, Leitman, S F, Carter, C S, Butz, R E, Read, E J, Fleisher, T A, Schneiderman, R D, Van Epps, D E, Spratt, S K, Maack, C A, Rokovich, J A, Cohen, L K, Gallin, J I
Published in Proceedings of the National Academy of Sciences - PNAS (28.10.1997)
Published in Proceedings of the National Academy of Sciences - PNAS (28.10.1997)
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Efficient and stable adeno-associated virus-mediated transduction in the skeletal muscle of adult immunocompetent mice
Snyder, R O, Spratt, S K, Lagarde, C, Bohl, D, Kaspar, B, Sloan, B, Cohen, L K, Danos, O
Published in Human gene therapy (01.11.1997)
Published in Human gene therapy (01.11.1997)
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Ocular Gene Transfer with Self-Complementary AAV Vectors
Yokoi, Katsutoshi, Kachi, Shu, Zhang, H. Steve, Gregory, Philip D, Spratt, S. Kaye, Samulski, R. Jude, Campochiaro, Peter A
Published in Investigative ophthalmology & visual science (01.07.2007)
Published in Investigative ophthalmology & visual science (01.07.2007)
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Gene therapy for traumatic central nervous system injury and stroke using an engineered zinc finger protein that upregulates VEGF-A
D'Onofrio, Philippe M, Thayapararajah, Mahinthan, Lysko, Meghan D, Magharious, Mark, Spratt, S Kaye, Lee, Gary, Ando, Dale, Surosky, Richard, Fehlings, Michael G, Koeberle, Paulo D
Published in Journal of neurotrauma (01.09.2011)
Published in Journal of neurotrauma (01.09.2011)
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Selective uptake and sustained expression of AAV vectors following subcutaneous delivery
Donahue, Brian A., McArthur, James G., Spratt, S. Kaye, Bohl, Delphine, Lagarde, Catherine, Sanchez, Lisa, Kaspar, Brian A., Sloan, Barbara A., Lee, Ya Li, Danos, Olivier, Snyder, Richard O.
Published in The journal of gene medicine (01.01.1999)
Published in The journal of gene medicine (01.01.1999)
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Isolation and characterization of the human pulmonary surfactant apoprotein gene
White, R T, Damm, D, Miller, J, Spratt, K, Schilling, J, Hawgood, S, Benson, B, Cordell, B
Published in Nature (London) (01.09.1985)
Published in Nature (London) (01.09.1985)
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Intravenous administration of CLN3 gene therapy for juvenile neuronal ceroid lipofuscinosis
Kerns, Scott, Daum, J., Bosch, M., Fallet, R., Odvody, J., Henson, Kari, Spratt, Kaye, Kielian, Tammy
Published in Molecular genetics and metabolism (01.02.2018)
Published in Molecular genetics and metabolism (01.02.2018)
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