Lapatinib-induced liver injury characterized by class II HLA and Gilbert's syndrome genotypes
Spraggs, C F, Parham, L R, Hunt, C M, Dollery, C T
Published in Clinical pharmacology and therapeutics (01.04.2012)
Published in Clinical pharmacology and therapeutics (01.04.2012)
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Antiemetic activity of the NK1 receptor antagonist GR205171 in the treatment of established postoperative nausea and vomiting after major gynaecological surgery
Diemunsch, P, Schoeffler, P, Bryssine, B, Cheli-Muller, L E, Lees, J, McQuade, B A, Spraggs, C F
Published in British journal of anaesthesia : BJA (01.02.1999)
Published in British journal of anaesthesia : BJA (01.02.1999)
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Pazopanib-induced hyperbilirubinemia is associated with Gilbert's syndrome UGT1A1 polymorphism
Xu, C-F, Reck, B H, Xue, Z, Huang, L, Baker, K L, Chen, M, Chen, E P, Ellens, H E, Mooser, V E, Cardon, L R, Spraggs, C F, Pandite, L
Published in British journal of cancer (27.04.2010)
Published in British journal of cancer (27.04.2010)
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Comprehensive genome-wide evaluation of lapatinib-induced liver injury yields a single genetic signal centered on known risk allele HLA-DRB107:01
Parham, L R, Briley, L P, Li, L, Shen, J, Newcombe, P J, King, K S, Slater, A J, Dilthey, A, Iqbal, Z, McVean, G, Cox, C J, Nelson, M R, Spraggs, C F
Published in The pharmacogenomics journal (01.04.2016)
Published in The pharmacogenomics journal (01.04.2016)
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IL8 polymorphisms and overall survival in pazopanib- or sunitinib-treated patients with renal cell carcinoma
Xu, C-F, Johnson, T, Garcia-Donas, J, Choueiri, T K, Sternberg, C N, Davis, I D, Bing, N, Deen, K C, Xue, Z, McCann, L, Esteban, E, Whittaker, J C, Spraggs, C F, Rodríguez-Antona, C, Pandite, L N, Motzer, R J
Published in British journal of cancer (31.03.2015)
Published in British journal of cancer (31.03.2015)
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Characterisation of the HLA-DRB107:01 biomarker for lapatinib-induced liver toxicity during treatment of early-stage breast cancer patients with lapatinib in combination with trastuzumab and/or taxanes
Spraggs, C F, Parham, L R, Briley, L P, Warren, L, Williams, L S, Fraser, D J, Jiang, Z, Aziz, Z, Ahmed, S, Demetriou, G, Mehta, A, Jackson, N, Byrne, J, Andersson, M, Toi, M, Harris, L, Gralow, J, Zujewski, J A, Crescenzo, R, Armour, A, Perez, E, Piccart, M
Published in The pharmacogenomics journal (22.05.2018)
Published in The pharmacogenomics journal (22.05.2018)
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Concomitant use of pazopanib and simvastatin increases the risk of transaminase elevations in patients with cancer
Xu, C.F., Xue, Z., Bing, N., King, K.S., McCann, L.A., de Souza, P.L., Goodman, V.L., Spraggs, C.F., Mooser, V.E., Pandite, L.N.
Published in Annals of oncology (01.09.2012)
Published in Annals of oncology (01.09.2012)
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Different effects of the BIM deletion polymorphism on treatment of solid tumors by the tyrosine kinase inhibitors (TKI) pazopanib, sunitinib, and lapatinib
Spraggs, C.F., Parham, L.R., Song, K., Briley, L.P., Johnson, T., Russo, M., Tada, H., du Bois, A., Xu, C.-F.
Published in Annals of oncology (01.07.2015)
Published in Annals of oncology (01.07.2015)
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Role of pepsin in the development of indomethacin‐induced antral ulceration in the rat
GAW, A. J., WILLIAMS, L. V., SPRAGGS, C. F., JORDAN, C. C.
Published in Alimentary pharmacology & therapeutics (01.04.1995)
Published in Alimentary pharmacology & therapeutics (01.04.1995)
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Transmucosal electrical resistance in rabbit isolated gastric mucosa during exposure to acid
Spencer, G E, Spraggs, C F, Stables, R, Hirst, B H
Published in The Journal of physiology (01.04.1992)
Published in The Journal of physiology (01.04.1992)
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RELATIONSHIP BETWEEN LESION FORMATION AND PERMEABILITY OF RAT GASTRIC MUCOSA TO H+ AND OTHER CATIONS
BUNCE, K.T., McCARTHY, J.J., SPRAGGS, C.F., STABLES, R.
Published in British journal of pharmacology (01.02.1982)
Published in British journal of pharmacology (01.02.1982)
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Selective activity of cyclokinins
Spraggs, C F, Margolius, H S, Cuthbert, A W
Published in Journal of pharmacy and pharmacology (01.04.1983)
Published in Journal of pharmacy and pharmacology (01.04.1983)
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Pharmacogenetic investigation of lapatinib-associated diarrhea in metastatic breast cancer clinical trials
Briley, L. P., Chiano, M., King, K., Casey, M., Preston, A. J., Sapunar, F., Mooser, V. E., Cardon, L. R., Spraggs, C. F.
Published in Journal of clinical oncology (20.05.2011)
Published in Journal of clinical oncology (20.05.2011)
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