Next-generation Fc receptor–targeting biologics for autoimmune diseases
Zuercher, Adrian W., Spirig, Rolf, Baz Morelli, Adriana, Rowe, Tony, Käsermann, Fabian
Published in Autoimmunity reviews (01.10.2019)
Published in Autoimmunity reviews (01.10.2019)
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Recombinant IgG1 Fc hexamers block cytotoxicity and pathological changes in experimental in vitro and rat models of neuromyelitis optica
Tradtrantip, Lukmanee, Felix, Christian M., Spirig, Rolf, Morelli, Adriana Baz, Verkman, A.S.
Published in Neuropharmacology (01.05.2018)
Published in Neuropharmacology (01.05.2018)
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rIgG1 Fc Hexamer Inhibits Antibody-Mediated Autoimmune Disease via Effects on Complement and FcγRs
Spirig, Rolf, Campbell, Ian K, Koernig, Sandra, Chen, Chao-Guang, Lewis, Bonnie J B, Butcher, Rebecca, Muir, Ineke, Taylor, Shirley, Chia, Jenny, Leong, David, Simmonds, Jason, Scotney, Pierre, Schmidt, Peter, Fabri, Louis, Hofmann, Andreas, Jordi, Monika, Spycher, Martin O, Cattepoel, Susann, Brasseit, Jennifer, Panousis, Con, Rowe, Tony, Branch, Donald R, Baz Morelli, Adriana, Käsermann, Fabian, Zuercher, Adrian W
Published in The Journal of immunology (1950) (15.04.2018)
Published in The Journal of immunology (1950) (15.04.2018)
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Neutrophil extracellular traps and citrullinated fibrinogen contribute to injury in a porcine model of limb ischemia and reperfusion
Zollet, Valentina, Arenas Hoyos, Isabel, Hirsiger, Stefanie, Brahim, Bilal Ben, Petrucci, Maria Francesca, Casoni, Daniela, Wang, Junhua, Spirig, Rolf, Nettelbeck, Kay, Garcia, Luisana, Fuest, Lena, Vögelin, Esther, Constantinescu, Mihai, Rieben, Robert
Published in Frontiers in immunology (09.09.2024)
Published in Frontiers in immunology (09.09.2024)
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Small-Molecule Immunosuppressive Drugs and Therapeutic Immunoglobulins Differentially Inhibit NK Cell Effector Functions in vitro
Pradier, Amandine, Papaserafeim, Maria, Li, Ning, Rietveld, Anke, Kaestel, Charlotte, Gruaz, Lyssia, Vonarburg, Cédric, Spirig, Rolf, Puga Yung, Gisella L, Seebach, Jörg D
Published in Frontiers in immunology (27.03.2019)
Published in Frontiers in immunology (27.03.2019)
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Journal Article
The Emerging Role of TLR and Innate Immunity in Cardiovascular Disease
Spirig, Rolf, Shaw, Sidney G., Tsui, Janice C. S.
Published in Cardiology research and practice (01.01.2012)
Published in Cardiology research and practice (01.01.2012)
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C1 esterase inhibitor reduces lower extremity ischemia/reperfusion injury and associated lung damage
Duehrkop, Claudia, Banz, Yara, Spirig, Rolf, Miescher, Sylvia, Nolte, Marc W, Spycher, Martin, Smith, Richard A G, Sacks, Steven H, Rieben, Robert
Published in PloS one (26.08.2013)
Published in PloS one (26.08.2013)
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Using the K/BxN mouse model of endogenous, chronic, rheumatoid arthritis for the evaluation of potential immunoglobulin-based therapeutic agents, including IVIg and Fc-μTP-L309C, a recombinant IgG1 Fc hexamer
Lewis, Bonnie J B, Ville, Jade, Blacquiere, Megan, Cen, Selena, Spirig, Rolf, Zuercher, Adrian W, Käsermann, Fabian, Branch, Donald R
Published in BMC immunology (04.12.2019)
Published in BMC immunology (04.12.2019)
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Reconstituted high-density lipoprotein modulates activation of human leukocytes
Spirig, Rolf, Schaub, Alexander, Kropf, Alain, Miescher, Sylvia, Spycher, Martin O, Rieben, Robert
Published in PloS one (14.08.2013)
Published in PloS one (14.08.2013)
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Journal Article
IVIG in autoimmune disease – Potential next generation biologics
Zuercher, Adrian W, Spirig, Rolf, Morelli, Adriana Baz, Käsermann, Fabian
Published in Autoimmunity reviews (01.08.2016)
Published in Autoimmunity reviews (01.08.2016)
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Journal Article
Effects of TLR agonists on the hypoxia-regulated transcription factor HIF-1alpha and dendritic cell maturation under normoxic conditions
Spirig, Rolf, Djafarzadeh, Siamak, Regueira, Tomas, Shaw, Sidney G, von Garnier, Christophe, Takala, Jukka, Jakob, Stephan M, Rieben, Robert, Lepper, Philipp M
Published in PloS one (07.06.2010)
Published in PloS one (07.06.2010)
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IgG hexamers initiate complement-dependent acute lung injury
Cleary, Simon J, Seo, Yurim, Tian, Jennifer J, Kwaan, Nicholas, Bulkley, David P, Bentlage, Arthur Eh, Vidarsson, Gestur, Boilard, Éric, Spirig, Rolf, Zimring, James C, Looney, Mark R
Published in The Journal of clinical investigation (01.06.2024)
Published in The Journal of clinical investigation (01.06.2024)
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Effects of C1 inhibitor on endothelial cell activation in a rat hind limb ischemia-reperfusion injury model
Zhang, Shengye, Shaw-Boden, Jane, Banz, Yara, Bongoni, Anjan K., Taddeo, Adriano, Spirig, Rolf, Nolte, Marc W., Cowan, Peter J., Rieben, Robert
Published in Journal of vascular surgery (01.12.2018)
Published in Journal of vascular surgery (01.12.2018)
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Effect of intravenous IgG therapy on natural killer cell function related to Fc gamma receptor gene expression
Papaserafeim, Maria, Jandus, Peter, Iancu Ferfoglia, Ruxandra, Nieke, Jan P., Vonarburg, Cédric, Spirig, Rolf, Puga Yung, Gisella L., Seebach, Jörg D.
Published in Journal of allergy and clinical immunology (01.09.2020)
Published in Journal of allergy and clinical immunology (01.09.2020)
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Modulation of Neutrophil Function by Recombinant Human IgG1 Fc Hexamer in the Endogenous K/BxN Mouse Model of Rheumatoid Arthritis
Almizraq, Ruqayyah J., Frias Boligan, Kayluz, Lewis, Bonnie J.B., Cen, Selena, Whetstone, Heather, Spirig, Rolf, Käsermann, Fabian, Campbell, Ian K., von Gunten, Stephan, Branch, Donald R.
Published in Pharmacology (01.03.2023)
Published in Pharmacology (01.03.2023)
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Journal Article
Effects of TLR Agonists on the Hypoxia-Regulated Transcription Factor HIF-1α and Dendritic Cell Maturation under Normoxic Conditions
Spirig, Rolf, Djafarzadeh, Siamak, Regueira, Tomas, Shaw, Sidney G., von Garnier, Christophe, Takala, Jukka, Jakob, Stephan M., Rieben, Robert, Lepper, Philipp M.
Published in PloS one (07.06.2010)
Published in PloS one (07.06.2010)
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