Increased cell senescence in human metabolic disorders
Spinelli, Rosa, Baboota, Ritesh Kumar, Gogg, Silvia, Beguinot, Francesco, Blüher, Matthias, Nerstedt, Annika, Smith, Ulf
Published in The Journal of clinical investigation (15.06.2023)
Published in The Journal of clinical investigation (15.06.2023)
Get full text
Journal Article
Nutritional Factors, DNA Methylation, and Risk of Type 2 Diabetes and Obesity: Perspectives and Challenges
Parrillo, Luca, Spinelli, Rosa, Nicolò, Antonella, Longo, Michele, Mirra, Paola, Raciti, Gregory Alexander, Miele, Claudia, Beguinot, Francesco
Published in International journal of molecular sciences (19.06.2019)
Published in International journal of molecular sciences (19.06.2019)
Get full text
Journal Article
Pathologic endoplasmic reticulum stress induced by glucotoxic insults inhibits adipocyte differentiation and induces an inflammatory phenotype
Longo, Michele, Spinelli, Rosa, D'Esposito, Vittoria, Zatterale, Federica, Fiory, Francesca, Nigro, Cecilia, Raciti, Gregory A., Miele, Claudia, Formisano, Pietro, Beguinot, Francesco, Di Jeso, Bruno
Published in Biochimica et biophysica acta (01.06.2016)
Published in Biochimica et biophysica acta (01.06.2016)
Get full text
Journal Article
Citrus aurantium L. dry extracts promote C/ebpβ expression and improve adipocyte differentiation in 3T3-L1 cells
Raciti, Gregory Alexander, Fiory, Francesca, Campitelli, Michele, Desiderio, Antonella, Spinelli, Rosa, Longo, Michele, Nigro, Cecilia, Pepe, Giacomo, Sommella, Eduardo, Campiglia, Pietro, Formisano, Pietro, Beguinot, Francesco, Miele, Claudia
Published in PloS one (29.03.2018)
Published in PloS one (29.03.2018)
Get full text
Journal Article
Chronic hyperinsulinemia promotes human hepatocyte senescence
Baboota, Ritesh K., Spinelli, Rosa, Erlandsson, Malin C., Brandao, Bruna B., Lino, Marsel, Yang, Hong, Mardinoglu, Adil, Bokarewa, Maria I., Boucher, Jeremie, Kahn, C. Ronald, Smith, Ulf
Published in Molecular metabolism (Germany) (01.10.2022)
Published in Molecular metabolism (Germany) (01.10.2022)
Get full text
Journal Article
Altered H3K4me3 profile at the TFAM promoter causes mitochondrial alterations in preadipocytes from first-degree relatives of type 2 diabetics
Longo, Michele, Zatterale, Federica, Spinelli, Rosa, Naderi, Jamal, Parrillo, Luca, Florese, Pasqualina, Nigro, Cecilia, Leone, Alessia, Moccia, Augusta, Desiderio, Antonella, Raciti, Gregory A, Miele, Claudia, Smith, Ulf, Beguinot, Francesco
Published in Clinical epigenetics (07.09.2023)
Published in Clinical epigenetics (07.09.2023)
Get full text
Journal Article
Prostate health index (phi) and prostate cancer antigen 3 (PCA3) significantly improve diagnostic accuracy in patients undergoing prostate biopsy
Perdonà, Sisto, Bruzzese, Dario, Ferro, Matteo, Autorino, Riccardo, Marino, Ada, Mazzarella, Claudia, Perruolo, Giuseppe, Longo, Michele, Spinelli, Rosa, Di Lorenzo, Giuseppe, Oliva, Andrea, De Sio, Marco, Damiano, Rocco, Altieri, Vincenzo, Terracciano, Daniela
Published in The Prostate (15.02.2013)
Published in The Prostate (15.02.2013)
Get full text
Journal Article
Methylglyoxal Impairs the Pro-Angiogenic Ability of Mouse Adipose-Derived Stem Cells (mADSCs) via a Senescence-Associated Mechanism
Leone, Alessia, Nicolò, Antonella, Prevenzano, Immacolata, Zatterale, Federica, Longo, Michele, Desiderio, Antonella, Spinelli, Rosa, Campitelli, Michele, Conza, Domenico, Raciti, Gregory Alexander, Beguinot, Francesco, Nigro, Cecilia, Miele, Claudia
Published in Cells (Basel, Switzerland) (28.06.2023)
Published in Cells (Basel, Switzerland) (28.06.2023)
Get full text
Journal Article
The Transcription Factor HOXA5: Novel Insights into Metabolic Diseases and Adipose Tissue Dysfunction
Parrillo, Luca, Spinelli, Rosa, Longo, Michele, Zatterale, Federica, Santamaria, Gianluca, Leone, Alessia, Campitelli, Michele, Raciti, Gregory Alexander, Beguinot, Francesco
Published in Cells (Basel, Switzerland) (18.08.2023)
Published in Cells (Basel, Switzerland) (18.08.2023)
Get full text
Journal Article
Epigenetic silencing of the ANKRD26 gene correlates to the pro-inflammatory profile and increased cardio-metabolic risk factors in human obesity
Desiderio, Antonella, Longo, Michele, Parrillo, Luca, Campitelli, Michele, Cacace, Giuseppe, de Simone, Sonia, Spinelli, Rosa, Zatterale, Federica, Cabaro, Serena, Dolce, Pasquale, Formisano, Pietro, Milone, Marco, Miele, Claudia, Beguinot, Francesco, Raciti, Gregory A
Published in Clinical epigenetics (04.12.2019)
Published in Clinical epigenetics (04.12.2019)
Get full text
Journal Article
Epigenetic Dysregulation of the Homeobox A5 ( HOXA5 ) Gene Associates with Subcutaneous Adipocyte Hypertrophy in Human Obesity
Parrillo, Luca, Spinelli, Rosa, Costanzo, Mattia, Florese, Pasqualina, Cabaro, Serena, Desiderio, Antonella, Prevenzano, Immacolata, Raciti, Gregory Alexander, Smith, Ulf, Miele, Claudia, Formisano, Pietro, Napoli, Raffaele, Beguinot, Francesco
Published in Cells (Basel, Switzerland) (18.02.2022)
Published in Cells (Basel, Switzerland) (18.02.2022)
Get full text
Journal Article
Reactive oxygen species regulate the levels of dual oxidase (Duox1-2) in human neuroblastoma cells
Damiano, Simona, Fusco, Roberta, Morano, Annalisa, De Mizio, Mariarosaria, Paternò, Roberto, De Rosa, Antonella, Spinelli, Rosa, Amente, Stefano, Frunzio, Rodolfo, Mondola, Paolo, Miot, Francoise, Laccetti, Paolo, Santillo, Mariarosaria, Avvedimento, Enrico Vittorio
Published in PloS one (16.04.2012)
Published in PloS one (16.04.2012)
Get full text
Journal Article
Toll-Like Receptor-Positive Cells and Recognition of Pathogens: How Human Myeloid Dendritic Cells Respond to In Vitro Infection with Leishmania infantum
Pepe, Maria, Altamura, Maria, Spinelli, Rosa, Calvello, Rosa, Saccia, Matteo, Cavallo, Pasqua, Covelli, Vito, Jirillo, Emilio, Brandonisio, Olga
Published in Current pharmaceutical design (01.11.2006)
Published in Current pharmaceutical design (01.11.2006)
Get full text
Journal Article
Hypomethylation at PANDAR promoter progressively induces senescence in adipocyte precursor cells in subjects with obesity and type 2 diabetes
Desiderio, Antonella, Pastorino, Monica, Campitelli, Michele, Prevenzano, Immacolata, De Palma, Fatima Domenica Elisa, Spinelli, Rosa, Parrillo, Luca, Longo, Michele, Milone, Marco, Miele, Claudia, Raciti, Gregory Alexander, Beguinot, Francesco
Published in The FASEB journal (15.10.2024)
Published in The FASEB journal (15.10.2024)
Get full text
Journal Article
KCTD1: A novel modulator of adipogenesis through the interaction with the transcription factor AP2α
Pirone, Luciano, Smaldone, Giovanni, Spinelli, Rosa, Barberisi, Manlio, Beguinot, Francesco, Vitagliano, Luigi, Miele, Claudia, Di Gaetano, Sonia, Raciti, Gregory Alexander, Pedone, Emilia
Published in Biochimica et biophysica acta. Molecular and cell biology of lipids (01.12.2019)
Published in Biochimica et biophysica acta. Molecular and cell biology of lipids (01.12.2019)
Get full text
Journal Article
ZMAT3 hypomethylation contributes to early senescence of preadipocytes from healthy first‐degree relatives of type 2 diabetics
Spinelli, Rosa, Florese, Pasqualina, Parrillo, Luca, Zatterale, Federica, Longo, Michele, D’Esposito, Vittoria, Desiderio, Antonella, Nerstedt, Annika, Gustafson, Birgit, Formisano, Pietro, Miele, Claudia, Raciti, Gregory Alexander, Napoli, Raffaele, Smith, Ulf, Beguinot, Francesco
Published in Aging cell (01.03.2022)
Published in Aging cell (01.03.2022)
Get full text
Journal Article
Adipose microenvironment promotes triple negative breast cancer cell invasiveness and dissemination by producing CCL5
D'Esposito, Vittoria, Liguoro, Domenico, Ambrosio, Maria Rosaria, Collina, Francesca, Cantile, Monica, Spinelli, Rosa, Raciti, Gregory Alexander, Miele, Claudia, Valentino, Rossella, Campiglia, Pietro, De Laurentiis, Michelino, Di Bonito, Maurizio, Botti, Gerardo, Franco, Renato, Beguinot, Francesco, Formisano, Pietro
Published in Oncotarget (26.04.2016)
Published in Oncotarget (26.04.2016)
Get full text
Journal Article
IL‐3 synergises with basophil‐derived IL‐4 and IL‐13 to promote the alternative activation of human monocytes
Borriello, Francesco, Longo, Michele, Spinelli, Rosa, Pecoraro, Antonio, Granata, Francescopaolo, Staiano, Rosaria Ilaria, Loffredo, Stefania, Spadaro, Giuseppe, Beguinot, Francesco, Schroeder, John, Marone, Gianni
Published in European journal of immunology (01.07.2015)
Published in European journal of immunology (01.07.2015)
Get full text
Journal Article
Epigenetic modifications of the Zfp/ZNF423 gene control murine adipogenic commitment and are dysregulated in human hypertrophic obesity
Longo, Michele, Raciti, Gregory A., Zatterale, Federica, Parrillo, Luca, Desiderio, Antonella, Spinelli, Rosa, Hammarstedt, Ann, Hedjazifar, Shahram, Hoffmann, Jenny M., Nigro, Cecilia, Mirra, Paola, Fiory, Francesca, Formisano, Pietro, Miele, Claudia, Smith, Ulf, Beguinot, Francesco
Published in Diabetologia (01.02.2018)
Published in Diabetologia (01.02.2018)
Get full text
Journal Article