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Published in Nature communications (03.11.2021)
Published in Nature communications (03.11.2021)
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Alternative splicing regulates mouse embryonic stem cell pluripotency and differentiation
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Published in Proceedings of the National Academy of Sciences - PNAS (08.06.2010)
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Antibody repertoire analysis of mouse immunization protocols using microfluidics and molecular genomics
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AKAP13 Rho-GEF and PKD-binding domain deficient mice develop normally but have an abnormal response to β-adrenergic-induced cardiac hypertrophy
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Published in PloS one (26.04.2013)
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Published in Antibodies (Basel) (19.02.2019)
Published in Antibodies (Basel) (19.02.2019)
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Stitchr: stitching coding TCR nucleotide sequences from V/J/CDR3 information
Heather, James M, Spindler, Matthew J, Alonso, Marta Herrero, Shui, Yifang Ivana, Millar, David G, Johnson, David S, Cobbold, Mark, Hata, Aaron N
Published in Nucleic acids research (08.07.2022)
Published in Nucleic acids research (08.07.2022)
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Massively parallel interrogation and mining of natively paired human TCRαβ repertoires
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Published in Nature biotechnology (01.05.2020)
Published in Nature biotechnology (01.05.2020)
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Generation of recombinant hyperimmune globulins from diverse B-cell repertoires
Keating, Sheila M., Mizrahi, Rena A., Adams, Matthew S., Asensio, Michael A., Benzie, Emily, Carter, Kyle P., Chiang, Yao, Edgar, Robert C., Gautam, Bishal K., Gras, Ashley, Leong, Jackson, Leong, Renee, Lim, Yoong Wearn, Manickam, Vishal A., Medina-Cucurella, Angelica V., Niedecken, Ariel R., Saini, Jasmeen, Simons, Jan Fredrik, Spindler, Matthew J., Stadtmiller, Kacy, Tinsley, Brendan, Wagner, Ellen K., Wayham, Nicholas, Tracy, LaRee, Lundberg, Carina Vingsbo, Büscher, Dirk, Terencio, Jose Vicente, Roalfe, Lucy, Pearce, Emma, Richardson, Hayley, Goldblatt, David, Ramjag, Anushka T., Carrington, Christine V. F., Simmons, Graham, Muench, Marcus O., Chamow, Steven M., Monroe, Bryan, Olson, Charles, Oguin, Thomas H., Lynch, Heather, Jeanfreau, Robert, Mosher, Rachel A., Walch, Matthew J., Bartley, Christopher R., Ross, Carl A., Meyer, Everett H., Adler, Adam S., Johnson, David S.
Published in Nature biotechnology (01.08.2021)
Published in Nature biotechnology (01.08.2021)
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Rare, high-affinity anti-pathogen antibodies from human repertoires, discovered using microfluidics and molecular genomics
Adler, Adam S, Mizrahi, Rena A, Spindler, Matthew J, Adams, Matthew S, Asensio, Michael A, Edgar, Robert C, Leong, Jackson, Leong, Renee, Roalfe, Lucy, White, Rebecca, Goldblatt, David, Johnson, David S
Published in mAbs (17.11.2017)
Published in mAbs (17.11.2017)
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A natively paired antibody library yields drug leads with higher sensitivity and specificity than a randomly paired antibody library
Adler, Adam S, Bedinger, Daniel, Adams, Matthew S, Asensio, Michael A, Edgar, Robert C, Leong, Renee, Leong, Jackson, Mizrahi, Rena A, Spindler, Matthew J, Bandi, Srinivasa Rao, Huang, Haichun, Tawde, Pallavi, Brams, Peter, Johnson, David S
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Published in mAbs (03.04.2018)
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Published in mAbs (17.11.2017)
Published in mAbs (17.11.2017)
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Taglieri, Domenico M, Johnson, Keven R, Burmeister, Brian T, Monasky, Michelle M, Spindler, Matthew J, DeSantiago, Jaime, Banach, Kathrin, Conklin, Bruce R, Carnegie, Graeme K
Published in Journal of molecular and cellular cardiology (01.01.2014)
Published in Journal of molecular and cellular cardiology (01.01.2014)
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A robust method to derive functional neural crest cells from human pluripotent stem cells
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Published in American journal of stem cells (01.01.2013)
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Published in American journal of stem cells (01.01.2013)
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High-throughput screening for rare antigen-reactive TCRs using natively-paired TCRαβ expression libraries generated from millions diverse primary T cells
Spindler, Matthew J, Nelson, Ayla L, Heather, James M, Wagner, Ellen K, Adler, Adam S, Johnson, David S
Published in The Journal of immunology (1950) (01.05.2020)
Published in The Journal of immunology (1950) (01.05.2020)
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Gain-of-function cardiomyopathic mutations in RBM20 rewire splicing regulation and re-distribute ribonucleoprotein aggregates within processing bodies
Fenix, Aidan M, Miyaoka, Yuichiro, Bertero, Alessandro, Blue, Steven, Spindler, Matthew J, Tan, Kenneth Kb, Perez-Bermejo, Juan A, Chan, Amanda H, Mayer, Steven J, Nguyen, Trieu, Russell, Caitlin R, Lizarraga, Paweena, Truong, Annie, Po-Lin, So, Kulkarni, Aishwarya, Chetal, Kashish, Sathe, Shashank, Sniadecki, Nathan J, Yeo, Gene W, Murry, Charles E, Salomonis, Nathan
Published in bioRxiv (03.06.2021)
Published in bioRxiv (03.06.2021)
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Paper
Antibody repertoire analysis of mouse immunization protocols using microfluidics and molecular genomics
Asensio, Michael A., Lim, Yoong Wearn, Wayham, Nicholas, Stadtmiller, Kacy, Edgar, Robert C., Leong, Jackson, Leong, Renee, Mizrahi, Rena A., Adams, Matthew S., Simons, Jan Fredrik, Spindler, Matthew J., Johnson, David S., Adler, Adam S.
Published in mAbs (04.07.2019)
Published in mAbs (04.07.2019)
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Rare, high-affinity mouse anti-PD-1 antibodies that function in checkpoint blockade, discovered using microfluidics and molecular genomics
Adler, Adam S., Mizrahi, Rena A., Spindler, Matthew J., Adams, Matthew S., Asensio, Michael A., Edgar, Robert C., Leong, Jackson, Leong, Renee, Johnson, David S.
Published in mAbs (17.11.2017)
Published in mAbs (17.11.2017)
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