MEK and PI3K-AKT inhibitors synergistically block activated IL7 receptor signaling in T-cell acute lymphoblastic leukemia
Canté-Barrett, K, Spijkers-Hagelstein, J A P, Buijs-Gladdines, J G C A M, Uitdehaag, J C M, Smits, W K, van der Zwet, J, Buijsman, R C, Zaman, G J R, Pieters, R, Meijerink, J P P
Published in Leukemia (01.09.2016)
Published in Leukemia (01.09.2016)
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Journal Article
Hypertension is associated with marked alterations in sphingolipid biology: a potential role for ceramide
Spijkers, Léon J A, van den Akker, Rob F P, Janssen, Ben J A, Debets, Jacques J, De Mey, Jo G R, Stroes, Erik S G, van den Born, Bert-Jan H, Wijesinghe, Dayanjan S, Chalfant, Charles E, MacAleese, Luke, Eijkel, Gert B, Heeren, Ron M A, Alewijnse, Astrid E, Peters, Stephan L M
Published in PloS one (19.07.2011)
Published in PloS one (19.07.2011)
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Journal Article
Soluble syndecan-1 and glycosaminoglycans in preeclamptic and normotensive pregnancies
Hassani Lahsinoui, H., Amraoui, F., Spijkers, L. J. A., Veenboer, G. J. M., Peters, S. L. M., van Vlies, N., Vogt, L., Ris-Stalpers, C., van den Born, B. J. H., Afink, G. B.
Published in Scientific reports (23.02.2021)
Published in Scientific reports (23.02.2021)
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Journal Article
Sphingosine-1-phosphate receptor 3 mediates sphingosine-1-phosphate induced release of weibel-palade bodies from endothelial cells
van Hooren, Kathinka W E M, Spijkers, Léon J A, van Breevoort, Dorothee, Fernandez-Borja, Mar, Bierings, Ruben, van Buul, Jaap D, Alewijnse, Astrid E, Peters, Stephan L M, Voorberg, Jan
Published in PloS one (14.03.2014)
Published in PloS one (14.03.2014)
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Journal Article
Sphingosine‐1‐Phosphate Receptor 1 Regulates Cardiac Function by Modulating Ca2+ Sensitivity and Na+/H+ Exchange and Mediates Protection by Ischemic Preconditioning
Keul, Petra, Borren, Marcel M. G. J., Ghanem, Alexander, Müller, Frank Ulrich, Baartscheer, Antonius, Verkerk, Arie O., Stümpel, Frank, Schulte, Jan Sebastian, Hamdani, Nazha, Linke, Wolfgang A., Loenen, Pieter, Matus, Marek, Schmitz, Wilhelm, Stypmann, Jörg, Tiemann, Klaus, Ravesloot, Jan‐Hindrik, Alewijnse, Astrid E., Hermann, Sven, Spijkers, Léon J. A., Hiller, Karl‐Heinz, Herr, Deron, Heusch, Gerd, Schäfers, Michael, Peters, Stephan L. M., Chun, Jerold, Levkau, Bodo
Published in Journal of the American Heart Association (20.05.2016)
Published in Journal of the American Heart Association (20.05.2016)
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Journal Article
Heterogeneity in arterial remodeling among sublines of spontaneously hypertensive rats
Bakker, Erik N T P, Groma, Gergely, Spijkers, Léon J A, de Vos, Judith, van Weert, Angela, van Veen, Henk, Everts, Vincent, Arribas, Silvia M, VanBavel, Ed
Published in PloS one (24.09.2014)
Published in PloS one (24.09.2014)
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Journal Article
Antihypertensive treatment differentially affects vascular sphingolipid biology in spontaneously hypertensive rats
Spijkers, Léon J A, Janssen, Ben J A, Nelissen, Jelly, Meens, Merlijn J P M T, Wijesinghe, Dayanjan, Chalfant, Charles E, De Mey, Jo G R, Alewijnse, Astrid E, Peters, Stephan L M
Published in PloS one (15.12.2011)
Published in PloS one (15.12.2011)
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Journal Article
Liquid−Solid Mass Transfer in Agitated Slurry Reactors and Rotating Solid Foam Reactors
Tschentscher, R, Spijkers, R. J. P, Nijhuis, T. A, van der Schaaf, J, Schouten, J. C
Published in Industrial & engineering chemistry research (03.11.2010)
Published in Industrial & engineering chemistry research (03.11.2010)
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Journal Article
Conference Proceeding
Plasma ceramide is increased and associated with proteinuria in women with pre-eclampsia and HELLP syndrome
Amraoui, Fouad, Hassani Lahsinoui, Hajar, Spijkers, Leon J.A., Vogt, Liffert, Peters, Stephan L.M., Wijesinghe, Dayanjan S., Warncke, Urszula O., Chalfant, Charles E., Ris-Stalpers, Carrie, van den Born, Bert-Jan H., Afink, Gijs B.
Published in Pregnancy hypertension (01.01.2020)
Published in Pregnancy hypertension (01.01.2020)
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Journal Article
Dietary fish oil improves endothelial function and lowers blood pressure via suppression of sphingolipid-mediated contractions in spontaneously hypertensive rats
van den Elsen, Lieke W J, Spijkers, Léon J A, van den Akker, Rob F P, van Winssen, Aggie M H, Balvers, Martin, Wijesinghe, Dayanjan S, Chalfant, Charles E, Garssen, Johan, Willemsen, Linette E M, Alewijnse, Astrid E, Peters, Stephan L M
Published in Journal of hypertension (01.05.2014)
Published in Journal of hypertension (01.05.2014)
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Journal Article
Frequencies and prognostic impact of RAS mutations in MLL-rearranged acute lymphoblastic leukemia in infants
Driessen, E. M. C., van Roon, E. H. J., Spijkers-Hagelstein, J. A. P., Schneider, P., de Lorenzo, P., Valsecchi, M. G., Pieters, R., Stam, R. W.
Published in Haematologica (Roma) (01.06.2013)
Published in Haematologica (Roma) (01.06.2013)
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Journal Article
Monitoring cobalamin inactivation during nitrous oxide anesthesia by determination of homocysteine and folate in plasma and urine
Ermens, A A, Refsum, H, Rupreht, J, Spijkers, L J, Guttormsen, A B, Lindemans, J, Ueland, P M, Abels, J
Published in Clinical pharmacology and therapeutics (01.04.1991)
Published in Clinical pharmacology and therapeutics (01.04.1991)
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Journal Article
Sphingolipids and the orchestration of endothelium-derived vasoactive factors: When endothelial function demands greasing
Spijkers, Leon J.A., Academic Medical Center, Amsterdam, the Netherlands, Alewijnse, Astrid E., Academic Medical Center, Amsterdam, the Netherlands, Peters, Stephan L.M., Academic Medical Center, Amsterdam, the Netherlands
Published in Molecules and cells (01.02.2010)
Published in Molecules and cells (01.02.2010)
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Journal Article
Toxicity of methotrexate in rats preexposed to nitrous oxide
ERMENS, A. A. M, SCHOESTER, M, SPIJKERS, L. J. M, LINDEMANS, J, ABELS, J
Published in Cancer research (Chicago, Ill.) (15.11.1989)
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Published in Cancer research (Chicago, Ill.) (15.11.1989)
Journal Article
A patient-centred instrument for assessment of quality of breast cancer care: results of a pilot questionnaire
de Kok, M, Sixma, H J M, van der Weijden, T, Kessels, A G H, Dirksen, C D, Spijkers, K F J, van de Velde, C J H, Roukema, J A, van der Ent, F W C, Finaly-Marais, C, von Meyenfeldt, M F
Published in Quality & safety in health care (01.12.2010)
Published in Quality & safety in health care (01.12.2010)
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