Assessing Different Classification Methods for Virtual Screening
Plewczynski, Dariusz, Spieser, Stéphane A. H, Koch, Uwe
Published in Journal of chemical information and modeling (01.05.2006)
Published in Journal of chemical information and modeling (01.05.2006)
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Journal Article
H1PVAT is a novel and potent early-stage inhibitor of poliovirus replication that targets VP1
TIJSMA, Aloys, THIBAUT, Hendrik Jan, MARCHAND, Arnaud, CHALTIN, Patrick, NEYTS, Johan, LEYSSEN, Pieter, SPIESER, Stéphane A. H, DE PALMA, Armando, KOUKNI, Mohamed, RHODEN, Eric, OBERSTE, Steve, PÜRSTINGER, Gerhard, VOLNY-LURAGHI, Antonia, MARTIN, Javier
Published in Antiviral research (01.10.2014)
Published in Antiviral research (01.10.2014)
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4-Hydroxy-5-pyrrolinone-3-carboxamide HIV-1 integrase inhibitors
Pace, Paola, Spieser, Stéphane A.H., Summa, Vincenzo
Published in Bioorganic & medicinal chemistry (15.07.2008)
Published in Bioorganic & medicinal chemistry (15.07.2008)
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Journal Article
Dihydroxy-pyrimidine and N-methylpyrimidone HIV-integrase inhibitors: Improving cell based activity by the quaternarization of a chiral center
Nizi, Emanuela, Orsale, Maria Vittoria, Crescenzi, Benedetta, Pescatore, Giovanna, Muraglia, Ester, Alfieri, Anna, Gardelli, Cristina, Spieser, Stéphane A.H., Summa, Vincenzo
Published in Bioorganic & medicinal chemistry letters (15.08.2009)
Published in Bioorganic & medicinal chemistry letters (15.08.2009)
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Journal Article
Target specific compound identification using a support vector machine
Plewczynski, Dariusz, von Grotthuss, Marcin, Spieser, Stephane A H, Rychlewski, Leszek, Wyrwicz, Lucjan S, Ginalski, Krzysztof, Koch, Uwe
Published in Combinatorial chemistry & high throughput screening (01.03.2007)
Published in Combinatorial chemistry & high throughput screening (01.03.2007)
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Journal Article
Covalent Inhibition of Bacterial Quorum Sensing
Amara, Neri, Mashiach, Roi, Amar, Dotan, Krief, Pnina, Spieser, Stéphane A. H, Bottomley, Matthew J, Aharoni, Amir, Meijler, Michael M
Published in Journal of the American Chemical Society (05.08.2009)
Published in Journal of the American Chemical Society (05.08.2009)
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Journal Article
A Novel Irreversible TEAD Inhibitor, SWTX-143, Blocks Hippo Pathway Transcriptional Output and Causes Tumor Regression in Preclinical Mesothelioma Models
Hillen, Hanne, Candi, Aurélie, Vanderhoydonck, Bart, Kowalczyk, Weronika, Sansores-Garcia, Leticia, Kesikiadou, Elena C, Van Huffel, Leen, Spiessens, Lore, Nijs, Marnik, Soons, Erik, Haeck, Wanda, Klaassen, Hugo, Smets, Wim, Spieser, Stéphane A, Marchand, Arnaud, Chaltin, Patrick, Ciesielski, Fabrice, Debaene, Francois, Chen, Lei, Kamal, Adeela, Gwaltney, Stephen L, Versele, Matthias, Halder, Georg A
Published in Molecular cancer therapeutics (03.01.2024)
Published in Molecular cancer therapeutics (03.01.2024)
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Journal Article
Modifying Rap1-signalling by targeting Pde6δ is neuroprotective in models of Alzheimer's disease
Dumbacher, Michael, Van Dooren, Tom, Princen, Katrien, De Witte, Koen, Farinelli, Mélissa, Lievens, Sam, Tavernier, Jan, Dehaen, Wim, Wera, Stefaan, Winderickx, Joris, Allasia, Sara, Kilonda, Amuri, Spieser, Stéphane, Marchand, Arnaud, Chaltin, Patrick, Hoogenraad, Casper C, Griffioen, Gerard
Published in Molecular neurodegeneration (26.09.2018)
Published in Molecular neurodegeneration (26.09.2018)
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Journal Article
A Force Field for Phosphoric Acid: Comparison of Simulated with Experimental Data in the Solid and Liquid State
Spieser, Stéphane A. H, Leeflang, Bas R, Kroon-Batenburg, Loes M. J, Kroon, Jan
Published in The journal of physical chemistry. A, Molecules, spectroscopy, kinetics, environment, & general theory (10.08.2000)
Published in The journal of physical chemistry. A, Molecules, spectroscopy, kinetics, environment, & general theory (10.08.2000)
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Journal Article
Abstract 5229: Discovery of novel potent allosteric inhibitors of YAP/TAZ-TEAD transcription for the treatment of multiple solid tumor types addicted to Hippo signaling
Versele, Matthias, Candi, Aurélie, Nijs, Marnik, Haeck, Wanda, Klaassen, Hugo, Smets, Wim, Spieser, Stéphane, Vanderhoydonck, Bart, Marchand, Arnaud, Chaltin, Patrick, Sansores, Leticia, Halder, Georg
Published in Cancer research (Chicago, Ill.) (15.08.2020)
Published in Cancer research (Chicago, Ill.) (15.08.2020)
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Journal Article
2-PYRAZOLE ANILINES AND RELATED ANALOGS FOR INHIBITING YAP/TAZ-TEAD
VANDERHOYDONCK, Bart, MARCHAND, Arnaud, SPIESER, Stephane, VERSELE, Matthias, SMETS, Wim, HALDER, Georg, GWALTNEY, Stephen, CANDI, Aurelie
Year of Publication 01.08.2024
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Year of Publication 01.08.2024
Patent
2-PYRAZOLE ANILINES AND RELATED ANALOGS FOR INHIBITING YAP/TAZ-TEAD
VANDERHOYDONCK, Bart, MARCHAND, Arnaud, SPIESER, Stephane, VERSELE, Matthias, SMETS, Wim, HALDER, Georg, GWALTNEY, Stephen, L, CANDI, Aurelie
Year of Publication 30.10.2024
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Year of Publication 30.10.2024
Patent
2-PYRAZOLE ANILINES AND RELATED ANALOGS FOR INHIBITING YAP/TAZ-TEAD
VANDERHOYDONCK, Bart, MARCHAND, Arnaud, SPIESER, Stephane, VERSELE, Matthias, SMETS, Wim, HALDER, Georg, GWALTNEY, Stephen, CANDI, Aurelie
Year of Publication 30.11.2023
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Year of Publication 30.11.2023
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2-PYRAZOLE ANILINES AND RELATED ANALOGS FOR INHIBITING YAP/TAZ-TEAD
VANDERHOYDONCK, Bart, MARCHAND, Arnaud, SPIESER, Stephane, VERSELE, Matthias, SMETS, Wim, HALDER, Georg, GWALTNEY, Stephen, CANDI, Aurelie
Year of Publication 31.08.2023
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Year of Publication 31.08.2023
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2-PYRAZOLE ANILINES AND RELATED ANALOGS FOR INHIBITING YAP/TAZ-TEAD
VANDERHOYDONCK, Bart, MARCHAND, Arnaud, SPIESER, Stephane, VERSELE, Matthias, SMETS, Wim, HALDER, Georg, GWALTNEY, Stephen, CANDI, Aurelie
Year of Publication 29.06.2023
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Year of Publication 29.06.2023
Patent
Modifying Rap1-signalling by targeting Pde6[delta] is neuroprotective in models of Alzheimer's disease
Dumbacher, Michael, Van Dooren, Tom, Princen, Katrien, De Witte, Koen, Farinelli, Mélissa, Lievens, Sam, Tavernier, Jan, Dehaen, Wim, Wera, Stefaan, Winderickx, Joris, Allasia, Sara, Kilonda, Amuri, Spieser, Stéphane, Marchand, Arnaud, Chaltin, Patrick, Hoogenraad, Casper C, Griffioen, Gerard
Published in Molecular neurodegeneration (26.09.2018)
Published in Molecular neurodegeneration (26.09.2018)
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Journal Article
Indoles, indazoles, and related analogs for inhibiting YAP/TAZ-TEAD
SMETS, WIM, GWALTNEY, STEPHEN L, CANDI, AURELIE, VERSELE, MATTHIAS, SPIESER, STEPHANE, VANDERHOYDONCK, BART, MARCHAND, ARNAUD
Year of Publication 16.10.2023
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Year of Publication 16.10.2023
Patent
2-PYRAZOLE ANILINES AND RELATED ANALOGS FOR INHIBITING YAP/TAZ-TEAD
SMETS Wim, HALDER Georg, VANDERHOYDONCK Bart, GWALTNEY Stephen L, MARCHAND Arnaud, CANDI Aurelie, VERSELE Matthias, SPIESER Stephane
Year of Publication 20.08.2024
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Year of Publication 20.08.2024
Patent