Loading…
In Vivo Predictive Dissolution and Simulation Workshop Report: Facilitating the Development of Oral Drug Formulation and the Prediction of Oral Bioperformance
Tsume, Yasuhiro, Patel, Sanjaykumar, Fotaki, Nikoletta, Bergstrӧm, Christel, Amidon, Gordon L., Brasseur, James G., Mudie, Deanna M., Sun, Duxin, Bermejo, Marival, Gao, Ping, Zhu, Wei, Sperry, David C., Vertzoni, Maria, Parrott, Neil, Lionberger, Robert, Kambayashi, Atsushi, Hermans, Andre, Lu, Xujin, Amidon, Gregory E.
Published in The AAPS journal (06.09.2018)
Published in The AAPS journal (06.09.2018)
Get full text
Journal Article
Loading…
Loading…
Loading…
Loading…
Use of Gastrointestinal Simulator, Mass Transport Analysis, and Absorption Simulation to Investigate the Impact of pH Modifiers in Mitigating Weakly Basic Drugs’ Performance Issues Related to Gastric pH: Palbociclib Case Study
Kuminek, Gislaine, Salehi, Niloufar, Waltz, Nicholas M., Sperry, David C., Greenwood, Dale E., Hate, Siddhi S., Amidon, Gregory E.
Published in Molecular pharmaceutics (02.01.2023)
Published in Molecular pharmaceutics (02.01.2023)
Get full text
Journal Article
Loading…
Preclinical and clinical evaluation of a novel TRPA1 antagonist LY3526318
Broad, Lisa M., Suico, Jeffrey G., Turner, P. Kellie, Nie, Si, Johnson, Kirk W., Sanger, Helen E., Wegiel, Lindsay A., Sperry, David C., Remick, David, Moran, Magdalene, Malekiani, Sam, del Camino, Donato, Wu, Xinyuan, Chong, Jayhong A., Blair, Nathaniel T., Wilke, August V.
Published in Pain (Amsterdam) (01.08.2025)
Published in Pain (Amsterdam) (01.08.2025)
Get full text
Journal Article
Loading…
Improving Dissolution Behavior and Oral Absorption of Drugs with pH-Dependent Solubility Using pH Modifiers: A Physiologically Realistic Mass Transport Analysis
Salehi, Niloufar, Kuminek, Gislaine, Al-Gousous, Jozef, Sperry, David C, Greenwood, Dale E, Waltz, Nicholas M, Amidon, Gordon L, Ziff, Robert M, Amidon, Gregory E
Published in Molecular pharmaceutics (06.09.2021)
Published in Molecular pharmaceutics (06.09.2021)
Get full text
Journal Article
Loading…
Relative Bioavailability Risk Assessment: A Systematic Approach to Assessing In Vivo Risk Associated With CM&C-Related Changes
Aburub, Aktham, Sperry, David C., Bhattachar, Shobha, Lobo, Evelyn, Ding, Xuan, Rose, John P.
Published in Journal of pharmaceutical sciences (01.01.2019)
Published in Journal of pharmaceutical sciences (01.01.2019)
Get full text
Journal Article
Loading…
Loading…
Loading…
Development of an in vivo-relevant drug product performance method for an amorphous solid dispersion
Pack, Brian W., Babayan, Yelizaveta, Schrad, Mark A., Stroud, Paul A., Sperry, David C., White, Kevin C., Aburub, Aktham
Published in Journal of pharmaceutical and biomedical analysis (05.08.2017)
Published in Journal of pharmaceutical and biomedical analysis (05.08.2017)
Get full text
Journal Article
Loading…
Loading…
Loading…
FIP Guidelines for Dissolution Testing of Solid Oral Products
Friedel, Horst Dieter, Brown, Cynthia K., Barker, Amy R., Buhse, Lucinda F., Keitel, Susanne, Kraemer, Johannes, Morris, John Michael, Reppas, Christos, Sperry, David C., Sakai-Kato, Kumiko, Stickelmeyer, Mary P., Shah, Vinod P.
Published in Journal of pharmaceutical sciences (01.12.2018)
Published in Journal of pharmaceutical sciences (01.12.2018)
Get full text
Journal Article
Loading…
Loading…
Loading…
Development of a rapidly dispersing tablet of a poorly wettable compound—formulation DOE and mechanistic study of effect of formulation excipients on wetting of celecoxib
He, Xiaorong, Barone, Michael R., Marsac, Patrick J., Sperry, David C.
Published in International journal of pharmaceutics (02.04.2008)
Published in International journal of pharmaceutics (02.04.2008)
Get full text
Journal Article
Loading…
Spectroscopy and reactivity of size-selected Mg+-ammonia clusters
Lee, James I., Sperry, David C., Farrar, James M.
Published in The Journal of chemical physics (01.11.2004)
Published in The Journal of chemical physics (01.11.2004)
Get full text
Journal Article
Loading…
Photodissociation Spectra for Size-Selected Sr+(CH3OH) n and Sr+(CH3OD) n Clusters
Lee, James I, Qian, Jun, Sperry, David C, Midey, Anthony J, Donnelly, Stephen G, Farrar, James M
Published in The journal of physical chemistry. A, Molecules, spectroscopy, kinetics, environment, & general theory (24.10.2002)
Published in The journal of physical chemistry. A, Molecules, spectroscopy, kinetics, environment, & general theory (24.10.2002)
Get full text
Journal Article