Telomerase deficiency reflects age-associated changes in CD4+ T cells
Matthe, Diana M, Thoma, Oana-Maria, Sperka, Tobias, Neurath, Markus F, Waldner, Maximilian J
Published in Immunity & ageing (23.03.2022)
Published in Immunity & ageing (23.03.2022)
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Journal Article
Author Correction: Puma and p21 represent cooperating checkpoints limiting self-renewal and chromosomal instability of somatic stem cells in response to telomere dysfunction
Sperka, Tobias, Song, Zhangfa, Morita, Yohei, Nalapareddy, Kodandaramireddy, Guachalla, Luis Miguel, Lechel, André, Begus-Nahrmann, Yvonne, Burkhalter, Martin D., Mach, Monika, Schlaudraff, Falk, Liss, Birgit, Ju, Zhenyu, Speicher, Michael R., Rudolph, K. Lenhard
Published in Nature cell biology (01.03.2021)
Published in Nature cell biology (01.03.2021)
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Journal Article
Puma and p21 represent cooperating checkpoints limiting self-renewal and chromosomal instability of somatic stem cells in response to telomere dysfunction
Sperka, Tobias, Song, Zhangfa, Morita, Yohei, Nalapareddy, Kodandaramireddy, Guachalla, Luis Miguel, Lechel, André, Begus-Nahrmann, Yvonne, Burkhalter, Martin D., Mach, Monika, Schlaudraff, Falk, Liss, Birgit, Ju, Zhenyu, Speicher, Michael R., Rudolph, K. Lenhard
Published in Nature cell biology (01.01.2012)
Published in Nature cell biology (01.01.2012)
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Journal Article
Activation of Ras requires the ERM-dependent link of actin to the plasma membrane
Sperka, Tobias, Geissler, Katja J, Merkel, Ulrike, Scholl, Ingmar, Rubio, Ignacio, Herrlich, Peter, Morrison, Helen L
Published in PloS one (21.11.2011)
Published in PloS one (21.11.2011)
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Journal Article
Regulation of Son of sevenless by the membrane-actin linker protein ezrin
Geißler, Katja J., Jung, M. Juliane, Riecken, Lars Björn, Sperka, Tobias, Cui, Yan, Schacke, Stephan, Merkel, Ulrike, Markwart, Robby, Rubio, Ignacio, Than, Manuel E., Breithaupt, Constanze, Peuker, Sebastian, Seifert, Reinhard, Kaupp, Ulrich Benjamin, Herrlich, Peter, Morrison, Helen
Published in Proceedings of the National Academy of Sciences - PNAS (17.12.2013)
Published in Proceedings of the National Academy of Sciences - PNAS (17.12.2013)
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Journal Article
Properties of an Ezrin Mutant Defective in F-actin Binding
Saleh, Henri S., Merkel, Ulrike, Geißler, Katja J., Sperka, Tobias, Sechi, Antonio, Breithaupt, Constanze, Morrison, Helen
Published in Journal of molecular biology (30.01.2009)
Published in Journal of molecular biology (30.01.2009)
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Journal Article
DNA damage checkpoints in stem cells, ageing and cancer
Sperka, Tobias, Wang, Jianwei, Rudolph, K. Lenhard
Published in Nature reviews. Molecular cell biology (01.09.2012)
Published in Nature reviews. Molecular cell biology (01.09.2012)
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Journal Article
The NF2 tumor suppressor merlin interacts with Ras and RasGAP, which may modulate Ras signaling
Cui, Yan, Groth, Susann, Troutman, Scott, Carlstedt, Annemarie, Sperka, Tobias, Riecken, Lars Björn, Kissil, Joseph L., Jin, Hongchuan, Morrison, Helen
Published in Oncogene (01.09.2019)
Published in Oncogene (01.09.2019)
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Journal Article
Genome instability of ageing stem cells—Induction and defence mechanisms
Burkhalter, Martin D, Rudolph, K. Lenhard, Sperka, Tobias
Published in Ageing research reviews (01.09.2015)
Published in Ageing research reviews (01.09.2015)
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Journal Article
Wnt activity and basal niche position sensitize intestinal stem and progenitor cells to DNA damage
Tao, Si, Tang, Duozhuang, Morita, Yohei, Sperka, Tobias, Omrani, Omid, Lechel, André, Sakk, Vadim, Kraus, Johann, Kestler, Hans A, Kühl, Michael, Rudolph, Karl Lenhard
Published in The EMBO journal (04.03.2015)
Published in The EMBO journal (04.03.2015)
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Journal Article
Telomeric epigenetic response mediated by Gadd45a regulates stem cell aging and lifespan
Diao, Daojun, Wang, Hu, Li, Tangliang, Shi, Zhencan, Jin, Xiaoqing, Sperka, Tobias, Zhu, Xudong, Zhang, Meimei, Yang, Fan, Cong, Yusheng, Shen, Li, Zhan, Qimin, Yan, Jing, Song, Zhangfa, Ju, Zhenyu
Published in EMBO reports (01.10.2018)
Published in EMBO reports (01.10.2018)
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Journal Article
VEGFR2 Signaling Prevents Colorectal Cancer Cell Senescence to Promote Tumorigenesis in Mice With Colitis
Foersch, Sebastian, Sperka, Tobias, Lindner, Christina, Taut, Astrid, Rudolph, Karl L, Breier, Georg, Boxberger, Frank, Rau, Tilman T, Hartmann, Arndt, Stürzl, Michael, Wittkopf, Nadine, Haep, Lisa, Wirtz, Stefan, Neurath, Markus F, Waldner, Maximilian J
Published in Gastroenterology (New York, N.Y. 1943) (01.07.2015)
Published in Gastroenterology (New York, N.Y. 1943) (01.07.2015)
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Journal Article
Wnt activity and basal niche position sensitize intestinal stem and progenitor cells to DNA damage
Tao, Si, Tang, Duozhuang, Morita, Yohei, Sperka, Tobias, Omrani, Omid, Lechel, André, Sakk, Vadim, Kraus, Johann, Kestler, Hans A, Kühl, Michael, Rudolph, Karl Lenhard
Published in The EMBO journal (02.10.2017)
Published in The EMBO journal (02.10.2017)
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Journal Article
Mo1949 VEGF/VEGFR-2 Signaling Promotes Tumorigenesis in Colitis-Associated Carcinoma Through Inactivation of Premature Senescence in Intestinal Epithelial Cells
Foersch, Sebastian, Sperka, Tobias, Rudolph, Karl L, Breier, Georg, Wirtz, Stefan J, Neurath, Markus F, Waldner, Maximilian J
Published in Gastroenterology (New York, N.Y. 1943) (01.05.2013)
Published in Gastroenterology (New York, N.Y. 1943) (01.05.2013)
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