Mechanistic Studies Yield Improved Protocols for Base-Catalyzed Anti-Markovnikov Alcohol Addition Reactions
Luo, Chaosheng, Alegre-Requena, Juan V., Sujansky, Stephen J., Pajk, Spencer P., Gallegos, Liliana C., Paton, Robert S., Bandar, Jeffrey S.
Published in Journal of the American Chemical Society (08.06.2022)
Published in Journal of the American Chemical Society (08.06.2022)
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A base-catalyzed approach for the anti-Markovnikov hydration of styrene derivatives
Pajk, Spencer P, Qi, Zisong, Sujansky, Stephen J, Bandar, Jeffrey S
Published in Chemical science (Cambridge) (05.10.2022)
Published in Chemical science (Cambridge) (05.10.2022)
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Identification of MRTX1133, a Noncovalent, Potent, and Selective KRASG12D Inhibitor
Wang, Xiaolun, Allen, Shelley, Blake, James F, Bowcut, Vickie, Briere, David M, Calinisan, Andrew, Dahlke, Joshua R, Fell, Jay B, Fischer, John P, Gunn, Robin J, Hallin, Jill, Laguer, Jade, Lawson, J. David, Medwid, James, Newhouse, Brad, Nguyen, Phong, O’Leary, Jacob M, Olson, Peter, Pajk, Spencer, Rahbaek, Lisa, Rodriguez, Mareli, Smith, Christopher R, Tang, Tony P, Thomas, Nicole C, Vanderpool, Darin, Vigers, Guy P, Christensen, James G, Marx, Matthew A
Published in Journal of medicinal chemistry (24.02.2022)
Published in Journal of medicinal chemistry (24.02.2022)
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Journal Article
Discovery of Potent and Selective Covalent Inhibitors of HER2 WT and HER2 YVMA
Hicken, Erik J, Brown, Karin, Dwulet, Natalie C, Gaudino, John J, Hansen, Erik P, Hartley, Dylan P, Kowalski, John P, Laird, Ellen R, Lazzara, Nicholas C, Li, Bin, Mou, Tung-Chung, Mutryn, Marie F, Oko, Lauren, Pajk, Spencer, Pipal, Robert W, Rosen, Rachel Z, Shelp, Russell, Singh, Anurag, Wang, Jing, Wise, Courtney E, Wong, Christina, Wong, Jim Y
Published in Journal of medicinal chemistry (13.06.2024)
Published in Journal of medicinal chemistry (13.06.2024)
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Journal Article
Discovery of Potent and Selective Covalent Inhibitors of HER2WT and HER2YVMA
Hicken, Erik J., Brown, Karin, Dwulet, Natalie C., Gaudino, John J., Hansen, Erik P., Hartley, Dylan P., Kowalski, John P., Laird, Ellen R., Lazzara, Nicholas C., Li, Bin, Mou, Tung-Chung, Mutryn, Marie F., Oko, Lauren, Pajk, Spencer, Pipal, Robert W., Rosen, Rachel Z., Shelp, Russell, Singh, Anurag, Wang, Jing, Wise, Courtney E., Wong, Christina, Wong, Jim Y.
Published in Journal of medicinal chemistry (13.06.2024)
Published in Journal of medicinal chemistry (13.06.2024)
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Journal Article
Identification of MRTX1133, a Noncovalent, Potent, and Selective KRAS G12D Inhibitor
Wang, Xiaolun, Allen, Shelley, Blake, James F, Bowcut, Vickie, Briere, David M, Calinisan, Andrew, Dahlke, Joshua R, Fell, Jay B, Fischer, John P, Gunn, Robin J, Hallin, Jill, Laguer, Jade, Lawson, J David, Medwid, James, Newhouse, Brad, Nguyen, Phong, O'Leary, Jacob M, Olson, Peter, Pajk, Spencer, Rahbaek, Lisa, Rodriguez, Mareli, Smith, Christopher R, Tang, Tony P, Thomas, Nicole C, Vanderpool, Darin, Vigers, Guy P, Christensen, James G, Marx, Matthew A
Published in Journal of medicinal chemistry (24.02.2022)
Published in Journal of medicinal chemistry (24.02.2022)
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Journal Article
Hybrid Integration of Silicon Slot Photonics with Ferroelectric Nematic Liquid Crystal for Poling-Free Pockels-Effect Modulation
Onural, Deniz, Wang, Imbert, Chiang, Li-Yuan, Raja, Shiva, Zhang, Xinchang, Singh, Manuj, Li, Dingning, Dao, Howard, Pajk, Spencer, Sickler, Jason W., Pecinovsky, Cory, Popovic, Milos A.
Published in 2024 Conference on Lasers and Electro-Optics (CLEO) (05.05.2024)
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Published in 2024 Conference on Lasers and Electro-Optics (CLEO) (05.05.2024)
Conference Proceeding
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ELLIS, Bryan Daniel, PAJK, Spencer Phillip, ROSEN, Rachel Zoe, LAZZARA, Nicholas Charles, NEWHOUSE, Bradley Jon, LAIRD, Ellen Ruth, HICKEN, Erik James, SHELP, Russell Andrew
Year of Publication 28.08.2024
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Year of Publication 28.08.2024
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HER2 MUTATION INHIBITORS
ELLIS, Bryan Daniel, PAJK, Spencer Phillip, ROSEN, Rachel Zoe, LAZZARA, Nicholas Charles, NEWHOUSE, Bradley Jon, LAIRD, Ellen Ruth, HICKEN, Erik James, SHELP, Russell Andrew
Year of Publication 01.05.2024
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Year of Publication 01.05.2024
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HER2 MUTATION INHIBITORS
ELLIS, Bryan Daniel, PAJK, Spencer Phillip, LAZZARA, Nicholas Charles, NEWHOUSE, Bradley Jon, LAIRD, Ellen Ruth, HICKEN, Erik James, GAUDINO, John Joseph, BOYS, Mark Laurence
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Year of Publication 18.04.2024
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HER2 MUTATION INHIBITORS
ELLIS, Bryan Daniel, PAJK, Spencer Phillip, ROSEN, Rachel Zoe, LAZZARA, Nicholas Charles, NEWHOUSE, Bradley Jon, LAIRD, Ellen Ruth, HICKEN, Erik James, SHELP, Russell Andrew
Year of Publication 04.01.2024
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Year of Publication 04.01.2024
Patent
KRAS G12D INHIBITORS
LAWSON, John David, RODRIGUEZ, Martha E, BLAKE, James Francis, NGUYEN, Phong, O'LEARY, Jacob M, NEWHOUSE, Bradley J, DOERNER BARBAUR, Patrick Michael, PAJK, Spencer, FELL, Jay Bradford, MARX, Matthew Arnold, FISCHER, John, Peter, TANG, Tony Pisal
Year of Publication 25.09.2024
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Year of Publication 25.09.2024
Patent
KRAS G12D INHIBITORS
Newhouse, Bradley J, Rodriguez, Martha E, O'Leary, Jacob M, Pajk, Spencer, Blake, James Francis, Lawson, John David, Doerner Barbaur, Patrick Michael, Nguyen, Phong, Tang, Tony Pisal, Marx, Matthew Arnold, Fell, Jay Bradford, Fischer, John Peter
Year of Publication 01.02.2024
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Year of Publication 01.02.2024
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HER2 MUTATION INHIBITORS
ELLIS, Bryan Daniel, PAJK, Spencer Phillip, Rosen, Rachel Zoe, LAZZARA, Nicholas Charles, NEWHOUSE, Bradley Jon, LAIRD, Ellen Ruth, HICKEN, Erik James, Shelp, Russell Andrew
Year of Publication 09.02.2023
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Year of Publication 09.02.2023
Patent
HER2 MUTATION INHIBITORS
ELLIS, Bryan Daniel, PAJK, Spencer Phillip, LAZZARA, Nicholas Charles, NEWHOUSE, Bradley Jon, LAIRD, Ellen Ruth, HICKEN, Erik James, GAUDINO, John Joseph, BOYS, Mark Laurence
Year of Publication 26.01.2023
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Year of Publication 26.01.2023
Patent
KRAS G12D INHIBITORS
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Year of Publication 06.11.2024
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Year of Publication 06.11.2024
Patent
HER2 MUTATION INHIBITORS
ELLIS, BRYAN DANIEL, ROSEN, RACHEL ZOE, NEWHOUSE, BRADLEY JON, SHELP, RUSSELL ANDREW, PAJK, SPENCER PHILLIP, LAIRD, ELLEN RUTH, HICKEN, ERIK JAMES, LAZZARA, NICHOLAS CHARLES
Year of Publication 29.12.2022
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Year of Publication 29.12.2022
Patent
HER2 MUTATION INHIBITORS
ELLIS, Bryan Daniel, PAJK, Spencer Phillip, ROSEN, Rachel Zoe, LAZZARA, Nicholas Charles, NEWHOUSE, Bradley Jon, LAIRD, Ellen Ruth, HICKEN, Erik James, SHELP, Russell Andrew
Year of Publication 29.12.2022
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Year of Publication 29.12.2022
Patent
QUINAZOLIN-4-ONE DERIVATIVES USEFUL FOR THE TREATMENT OF BRAF-ASSOCIATED DISEASES AND DISORDERS
METCALF, Andrew Terrance, TARLTON, Eugene, LAIRD, Ellen Ruth, BROWN, Katie Keaton, BARBOUR, Patrick Michael, MORENO, David Austin, PRIGARO, Brett Joseph, PAJK, Spencer Phillip, NEWHOUSE, Bradley Jon, HICKEN, Erik James, REN, Li, COOK, Adam Wade, KAHN, Dean Russell
Year of Publication 27.09.2023
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Year of Publication 27.09.2023
Patent