Heterologous vaccination regimens with self-amplifying RNA and adenoviral COVID vaccines induce robust immune responses in mice
Spencer, Alexandra J., McKay, Paul F., Belij-Rammerstorfer, Sandra, Ulaszewska, Marta, Bissett, Cameron D., Hu, Kai, Samnuan, Karnyart, Blakney, Anna K., Wright, Daniel, Sharpe, Hannah R., Gilbride, Ciaran, Truby, Adam, Allen, Elizabeth R., Gilbert, Sarah C., Shattock, Robin J., Lambe, Teresa
Published in Nature communications (17.05.2021)
Published in Nature communications (17.05.2021)
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Viral vectors as vaccine platforms: from immunogenicity to impact
Ewer, Katie J, Lambe, Teresa, Rollier, Christine S, Spencer, Alexandra J, Hill, Adrian VS, Dorrell, Lucy
Published in Current opinion in immunology (01.08.2016)
Published in Current opinion in immunology (01.08.2016)
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MAIT cell activation augments adenovirus vector vaccine immunogenicity
Provine, Nicholas M, Amini, Ali, Garner, Lucy C, Spencer, Alexandra J, Dold, Christina, Hutchings, Claire, Silva Reyes, Laura, FitzPatrick, Michael E B, Chinnakannan, Senthil, Oguti, Blanche, Raymond, Meriel, Ulaszewska, Marta, Troise, Fulvia, Sharpe, Hannah, Morgan, Sophie B, Hinks, Timothy S C, Lambe, Teresa, Capone, Stefania, Folgori, Antonella, Barnes, Eleanor, Rollier, Christine S, Pollard, Andrew J, Klenerman, Paul
Published in Science (American Association for the Advancement of Science) (29.01.2021)
Published in Science (American Association for the Advancement of Science) (29.01.2021)
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A novel chimpanzee adenovirus vector with low human seroprevalence: improved systems for vector derivation and comparative immunogenicity
Dicks, Matthew D J, Spencer, Alexandra J, Edwards, Nick J, Wadell, Göran, Bojang, Kalifa, Gilbert, Sarah C, Hill, Adrian V S, Cottingham, Matthew G
Published in PloS one (13.07.2012)
Published in PloS one (13.07.2012)
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A PfRH5-Based Vaccine Is Efficacious against Heterologous Strain Blood-Stage Plasmodium falciparum Infection in Aotus Monkeys
Douglas, Alexander D., Baldeviano, G. Christian, Lucas, Carmen M., Lugo-Roman, Luis A., Crosnier, Cécile, Bartholdson, S. Josefin, Diouf, Ababacar, Miura, Kazutoyo, Lambert, Lynn E., Ventocilla, Julio A., Leiva, Karina P., Milne, Kathryn H., Illingworth, Joseph J., Spencer, Alexandra J., Hjerrild, Kathryn A., Alanine, Daniel G.W., Turner, Alison V., Moorhead, Jeromy T., Edgel, Kimberly A., Wu, Yimin, Long, Carole A., Wright, Gavin J., Lescano, Andrés G., Draper, Simon J.
Published in Cell host & microbe (14.01.2015)
Published in Cell host & microbe (14.01.2015)
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ChAdOx1 nCoV-19 (AZD1222) or nCoV-19-Beta (AZD2816) protect Syrian hamsters against Beta Delta and Omicron variants
van Doremalen, Neeltje, Schulz, Jonathan E., Adney, Danielle R., Saturday, Taylor A., Fischer, Robert J., Yinda, Claude Kwe, Thakur, Nazia, Newman, Joseph, Ulaszewska, Marta, Belij-Rammerstorfer, Sandra, Saturday, Greg, Spencer, Alexandra J., Bailey, Dalan, Russell, Colin A., Gilbert, Sarah C., Lambe, Teresa, Munster, Vincent J.
Published in Nature communications (08.08.2022)
Published in Nature communications (08.08.2022)
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Chimpanzee adenoviral vectors as vaccines for outbreak pathogens
Ewer, Katie, Sebastian, Sarah, Spencer, Alexandra J., Gilbert, Sarah, Hill, Adrian V. S., Lambe, Teresa
Published in Human vaccines & immunotherapeutics (02.12.2017)
Published in Human vaccines & immunotherapeutics (02.12.2017)
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Prime and target immunization protects against liver-stage malaria in mice
Gola, Anita, Silman, Daniel, Walters, Adam A, Sridhar, Saranya, Uderhardt, Stefan, Salman, Ahmed M, Halbroth, Benedict R, Bellamy, Duncan, Bowyer, Georgina, Powlson, Jonathan, Baker, Megan, Venkatraman, Navin, Poulton, Ian, Berrie, Eleanor, Roberts, Rachel, Lawrie, Alison M, Angus, Brian, Khan, Shahid M, Janse, Chris J, Ewer, Katie J, Germain, Ronald N, Spencer, Alexandra J, Hill, Adrian V S
Published in Science translational medicine (26.09.2018)
Published in Science translational medicine (26.09.2018)
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Potent immunogenicity and protective efficacy of a multi-pathogen vaccination targeting Ebola, Sudan, Marburg and Lassa viruse
Flaxman, Amy, Sebastian, Sarah, Appelberg, Sofia, Cha, Kuan M, Ulaszewska, Marta, Purushotham, Jyothi, Gilbride, Ciaran, Sharpe, Hannah, Spencer, Alexandra J, Bibi, Sagida, Wright, Daniel, Schmidt, Isabel, Dowall, Stuart, Easterbrook, Linda, Findlay-Wilson, Stephen, Gilbert, Sarah, Mirazimi, Ali, Lambe, Teresa
Published in PLoS pathogens (26.06.2024)
Published in PLoS pathogens (26.06.2024)
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A T cell-inducing influenza vaccine for the elderly: safety and immunogenicity of MVA-NP+M1 in adults aged over 50 years
Antrobus, Richard D, Lillie, Patrick J, Berthoud, Tamara K, Spencer, Alexandra J, McLaren, James E, Ladell, Kristin, Lambe, Teresa, Milicic, Anita, Price, David A, Hill, Adrian V S, Gilbert, Sarah C
Published in PloS one (31.10.2012)
Published in PloS one (31.10.2012)
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A booster dose enhances immunogenicity of the COVID-19 vaccine candidate ChAdOx1 nCoV-19 in aged mice
Silva-Cayetano, Alyssa, Foster, William S., Innocentin, Silvia, Belij-Rammerstorfer, Sandra, Spencer, Alexandra J., Burton, Oliver T., Fra-Bidó, Sigrid, Le Lee, Jia, Thakur, Nazia, Conceicao, Carina, Wright, Daniel, Barrett, Jordan, Evans-Bailey, Nicola, Noble, Carly, Bailey, Dalan, Liston, Adrian, Gilbert, Sarah C., Lambe, Teresa, Linterman, Michelle A.
Published in Med (12.03.2021)
Published in Med (12.03.2021)
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Ultra-low dose immunization and multi-component vaccination strategies enhance protection against malaria in mice
Collins, Katharine A., Brod, Florian, Snaith, Rebecca, Ulaszewska, Marta, Longley, Rhea J., Salman, Ahmed M., Gilbert, Sarah C., Spencer, Alexandra J., Franco, David, Ballou, W. Ripley, Hill, Adrian V. S.
Published in Scientific reports (24.05.2021)
Published in Scientific reports (24.05.2021)
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Combination of RTS,S and Pfs25-IMX313 Induces a Functional Antibody Response Against Malaria Infection and Transmission in Mice
Brod, Florian, Miura, Kazutoyo, Taylor, Iona, Li, Yuanyuan, Marini, Arianna, Salman, Ahmed M, Spencer, Alexandra J, Long, Carole A, Biswas, Sumi
Published in Frontiers in immunology (04.12.2018)
Published in Frontiers in immunology (04.12.2018)
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Preclinical Development and Assessment of Viral Vectors Expressing a Fusion Antigen of Plasmodium falciparum LSA1 and LSAP2 for Efficacy against Liver-Stage Malaria
Halbroth, Benedict R, Sebastian, Sarah, Salman, Ahmed M, Ulaszewska, Marta, Gola, Anita, Longley, Rhea J, Janse, Chris J, Khan, Shahid M, Hill, Adrian V S, Spencer, Alexandra J
Published in Infection and immunity (22.01.2020)
Published in Infection and immunity (22.01.2020)
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Phase Ia Clinical Evaluation of the Plasmodium falciparum Blood-stage Antigen MSP1 in ChAd63 and MVA Vaccine Vectors
Sheehy, Susanne H, Duncan, Christopher JA, Elias, Sean C, Collins, Katharine A, Ewer, Katie J, Spencer, Alexandra J, Williams, Andrew R, Halstead, Fenella D, Moretz, Samuel E, Miura, Kazutoyo, Epp, Christian, Dicks, Matthew DJ, Poulton, Ian D, Lawrie, Alison M, Berrie, Eleanor, Moyle, Sarah, Long, Carole A, Colloca, Stefano, Cortese, Riccardo, Gilbert, Sarah C, Nicosia, Alfredo, Hill, Adrian VS, Draper, Simon J
Published in Molecular therapy (01.12.2011)
Published in Molecular therapy (01.12.2011)
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Comparative assessment of vaccine vectors encoding ten malaria antigens identifies two protective liver-stage candidates
Longley, Rhea J., Salman, Ahmed M., Cottingham, Matthew G., Ewer, Katie, Janse, Chris J., Khan, Shahid M., Spencer, Alexandra J., Hill, Adrian V. S.
Published in Scientific reports (03.07.2015)
Published in Scientific reports (03.07.2015)
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Deep Immune Phenotyping and Single-Cell Transcriptomics Allow Identification of Circulating TRM-Like Cells Which Correlate With Liver-Stage Immunity and Vaccine-Induced Protection From Malaria
Noé, Andrés, Datoo, Mehreen S, Flaxman, Amy, Husainy, Mohammad Ali, Jenkin, Daniel, Bellamy, Duncan, Makinson, Rebecca A, Morter, Richard, Ramos Lopez, Fernando, Sheridan, Jonathan, Voukantsis, Dimitrios, Prasad, Naveen, Hill, Adrian V S, Ewer, Katie J, Spencer, Alexandra J
Published in Frontiers in immunology (07.02.2022)
Published in Frontiers in immunology (07.02.2022)
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Long-term thermostabilization of live poxviral and adenoviral vaccine vectors at supraphysiological temperatures in carbohydrate glass
Alcock, Robert, Cottingham, Matthew G, Rollier, Christine S, Furze, Julie, De Costa, Samodh D, Hanlon, Marian, Spencer, Alexandra J, Honeycutt, Jared D, Wyllie, David H, Gilbert, Sarah C, Bregu, Migena, Hill, Adrian V S
Published in Science translational medicine (17.02.2010)
Published in Science translational medicine (17.02.2010)
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Optimising Controlled Human Malaria Infection Studies Using Cryopreserved P. falciparum Parasites Administered by Needle and Syringe
Sheehy, Susanne H, Spencer, Alexandra J, Douglas, Alexander D, Sim, B Kim Lee, Longley, Rhea J, Edwards, Nick J, Poulton, Ian D, Kimani, Domtila, Williams, Andrew R, Anagnostou, Nicholas A, Roberts, Rachel, Kerridge, Simon, Voysey, Merryn, James, Eric R, Billingsley, Peter F, Gunasekera, Anusha, Lawrie, Alison M, Hoffman, Stephen L, Hill, Adrian V S
Published in PloS one (18.06.2013)
Published in PloS one (18.06.2013)
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