Raman micro-spectroscopy reveals the spatial distribution of fumarate in cells and tissues
Kamp, Marlous, Surmacki, Jakub, Segarra Mondejar, Marc, Young, Tim, Chrabaszcz, Karolina, Joud, Fadwa, Zecchini, Vincent, Speed, Alyson, Frezza, Christian, Bohndiek, Sarah E.
Published in Nature communications (25.06.2024)
Published in Nature communications (25.06.2024)
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Fumarate induces vesicular release of mtDNA to drive innate immunity
Zecchini, Vincent, Paupe, Vincent, Herranz-Montoya, Irene, Janssen, Joëlle, Wortel, Inge M. N., Morris, Jordan L., Ferguson, Ashley, Chowdury, Suvagata Roy, Segarra-Mondejar, Marc, Costa, Ana S. H., Pereira, Gonçalo C., Tronci, Laura, Young, Timothy, Nikitopoulou, Efterpi, Yang, Ming, Bihary, Dóra, Caicci, Federico, Nagashima, Shun, Speed, Alyson, Bokea, Kalliopi, Baig, Zara, Samarajiwa, Shamith, Tran, Maxine, Mitchell, Thomas, Johnson, Mark, Prudent, Julien, Frezza, Christian
Published in Nature (London) (16.03.2023)
Published in Nature (London) (16.03.2023)
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The renal lineage factor PAX8 controls oncogenic signalling in kidney cancer
Patel, Saroor A., Hirosue, Shoko, Rodrigues, Paulo, Vojtasova, Erika, Richardson, Emma K., Ge, Jianfeng, Syafruddin, Saiful E., Speed, Alyson, Papachristou, Evangelia K., Baker, David, Clarke, David, Purvis, Stephenie, Wesolowski, Ludovic, Dyas, Anna, Castillon, Leticia, Caraffini, Veronica, Bihary, Dóra, Yong, Cissy, Harrison, David J., Stewart, Grant D., Machiela, Mitchell J., Purdue, Mark P., Chanock, Stephen J., Warren, Anne Y., Samarajiwa, Shamith A., Carroll, Jason S., Vanharanta, Sakari
Published in Nature (London) (30.06.2022)
Published in Nature (London) (30.06.2022)
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Lung tumors with distinct p53 mutations respond similarly to p53 targeted therapy but exhibit genotype-specific statin sensitivity
Turrell, Frances K, Kerr, Emma M, Gao, Meiling, Thorpe, Hannah, Doherty, Gary J, Cridge, Jake, Shorthouse, David, Speed, Alyson, Samarajiwa, Shamith, Hall, Benjamin A, Griffiths, Meryl, Martins, Carla P
Published in Genes & development (01.07.2017)
Published in Genes & development (01.07.2017)
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Abstract PR002: Injury-associated transcriptional state transitions in early renal carcinogenesis
Hirosue, Shoko, Ge, Jianfeng, Castillon, Leticia, Rodrigues, Paulo, Bihary, Dóra, Speed, Alyson, Wesolowski, Ludovic, Caraffini, Veronica, Warren, Anne Y., Stewart, Grant D., Welsh, Sarah J., Mitchell, Thomas J., Matakidou, Athena, Seyednasrollah, Fatemeh S., Samarajiwa, Shamith A., Vanharanta, Sakari
Published in Cancer research (Chicago, Ill.) (15.08.2023)
Published in Cancer research (Chicago, Ill.) (15.08.2023)
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Abstract A015: Injury-associated transcriptional state transitions in early renal carcinogenesis
Hirosue, Shoko, Ge, Jianfeng, Castillon, Leticia, Rodrigues, Paulo, Bihary, Dóra, Speed, Alyson, Wesolowski, Ludovic, Caraffini, Veronica, Warren, Anne Y., Stewart, Grant D., Welsh, Sarah J., Mitchell, Thomas J., Matakidou, Athena, Seyednasrollah, Fatemeh S., Samarajiwa, Shamith A., Vanharanta, Sakari
Published in Cancer research (Chicago, Ill.) (15.08.2023)
Published in Cancer research (Chicago, Ill.) (15.08.2023)
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HIRA loss transforms FH -deficient cells
Valcarcel-Jimenez, Lorea, Rogerson, Connor, Yong, Cissy, Schmidt, Christina, Yang, Ming, Cremades-Rodelgo, Monica, Harle, Victoria, Offord, Victoria, Wong, Kim, Mora, Ariane, Speed, Alyson, Caraffini, Veronica, Tran, Maxine Gia Binh, Maher, Eamonn R, Stewart, Grant D, Vanharanta, Sakari, Adams, David J, Frezza, Christian
Published in Science advances (21.10.2022)
Published in Science advances (21.10.2022)
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