Gene silencing following siRNA delivery to skin via coated steel microneedles: In vitro and in vivo proof-of-concept
Chong, Rosalind H.E., Gonzalez-Gonzalez, Emilio, Lara, Maria F., Speaker, Tycho J., Contag, Christopher H., Kaspar, Roger L., Coulman, Sion A., Hargest, Rachel, Birchall, James C.
Published in Journal of controlled release (28.03.2013)
Published in Journal of controlled release (28.03.2013)
Get full text
Journal Article
Silencing of Reporter Gene Expression in Skin Using siRNAs and Expression of Plasmid DNA Delivered by a Soluble Protrusion Array Device (PAD)
Gonzalez-Gonzalez, Emilio, Speaker, Tycho J, Hickerson, Robyn P, Spitler, Ryan, Flores, Manuel A, Leake, Devin, Contag, Christopher H, Kaspar, Roger L
Published in Molecular therapy (01.09.2010)
Published in Molecular therapy (01.09.2010)
Get full text
Journal Article
Gene expression profiling in pachyonychia congenita skin
Cao, Yu-An, Hickerson, Robyn P, Seegmiller, Brandon L, Grapov, Dmitry, Gross, Maren M, Bessette, Marc R, Phinney, Brett S, Flores, Manuel A, Speaker, Tycho J, Vermeulen, Annaleen, Bravo, Albert A, Bruckner, Anna L, Milstone, Leonard M, Schwartz, Mary E, Rice, Robert H, Kaspar, Roger L
Published in Journal of dermatological science (01.03.2015)
Published in Journal of dermatological science (01.03.2015)
Get full text
Journal Article
Inhibition of CD44 gene expression in human skin models, using self-delivery short interfering RNA administered by dissolvable microneedle arrays
Lara, Maria Fernanda, González-González, Emilio, Speaker, Tycho J, Hickerson, Robyn P, Leake, Devin, Milstone, Leonard M, Contag, Christopher H, Kaspar, Roger L
Published in Human gene therapy (01.08.2012)
Published in Human gene therapy (01.08.2012)
Get more information
Journal Article
Imaging Functional Nucleic Acid Delivery to Skin
Kaspar, Roger L, Hickerson, Robyn P, González-González, Emilio, Flores, Manuel A, Speaker, Tycho P, Rogers, Faye A, Milstone, Leonard M, Contag, Christopher H
Published in Methods in molecular biology (Clifton, N.J.) (2016)
Published in Methods in molecular biology (Clifton, N.J.) (2016)
Get more information
Journal Article
Non-Invasive Intravital Imaging of siRNA-Mediated Mutant Keratin Gene Repression in Skin
Hickerson, Robyn P., Speaker, Tycho J., Lara, Maria Fernanda, González-González, Emilio, Flores, Manuel A., Contag, Christopher H., Kaspar, Roger L.
Published in Molecular imaging and biology (01.02.2016)
Published in Molecular imaging and biology (01.02.2016)
Get full text
Journal Article
Gene Silencing in Skin After Deposition of Self-Delivery siRNA With a Motorized Microneedle Array Device
Hickerson, Robyn P, Wey, Winston C, Rimm, David L, Speaker, Tycho, Suh, Susie, Flores, Manuel A, Gonzalez-Gonzalez, Emilio, Leake, Devin, Contag, Christopher H, Kaspar, Roger L
Published in Molecular therapy. Nucleic acids (01.10.2013)
Published in Molecular therapy. Nucleic acids (01.10.2013)
Get full text
Journal Article
Microencapsulation decreases the skin absorption of N, N-diethyl- m-toluamide (DEET)
Kasting, Gerald B., Bhatt, Varsha D., Speaker, Tycho J.
Published in Toxicology in vitro (01.03.2008)
Published in Toxicology in vitro (01.03.2008)
Get full text
Journal Article
Visualization of plasmid delivery to keratinocytes in mouse and human epidermis
González-González, Emilio, Kim, Yeu-Chun, Speaker, Tycho J, Hickerson, Robyn P, Spitler, Ryan, Birchall, James C, Lara, Maria Fernanda, Hu, Rong-Hua, Liang, Yanhua, Kirkiles-Smith, Nancy, Prausnitz, Mark R, Milstone, Leonard M, Contag, Christopher H, Kaspar, Roger L
Published in Scientific reports (2011)
Published in Scientific reports (2011)
Get full text
Journal Article
Assessing the risk of a clinically significant infection from a Microneedle Array Patch (MAP) product
Dul, Maria, Alali, Mohammed, Ameri, Mahmoud, Burke, Matthew Douglas, Craig, Christine M., Creelman, Benjamin Paul, Dick, Lisa, Donnelly, Ryan F., Eakins, Michael N., Frivold, Collrane, Forster, Angus Harry, Gilbert, Philippe-Alexandre, Henke, Stefan, Henry, Sebastien, Hunt, Desmond, Lewis, Hayley, Maibach, Howard I., Mistilis, Jessica Joyce, Park, Jung-Hwan, Prausnitz, Mark R., Robinson, David Kenneth, Hernandez, Carmen Amelia Rodriguez, Ross, Charles, Shin, Juyeop, Speaker, Tycho Joseph, Taylor, Kevin Michael, Zehrung, Darin, Birchall, James C., Jarrahian, Courtney, Coulman, Sion A.
Published in Journal of controlled release (01.09.2023)
Published in Journal of controlled release (01.09.2023)
Get full text
Journal Article
Skin-based soluble microneedle array mediated anti-malarial CSP vaccination (65.28)
Speaker, Tycho, Chang, Stella, Fairman, Jeff, Kaspar, Roger
Published in The Journal of immunology (1950) (01.04.2011)
Published in The Journal of immunology (1950) (01.04.2011)
Get full text
Journal Article
Adjuvanted Flu Vaccination Using a Novel High-Efficiency Hollow Microprotrusion Skin Patch (130.37)
Chang, Stella, Kaspar, Roger, Fairman, Jeff, Speaker, Tycho
Published in The Journal of immunology (1950) (01.04.2010)
Published in The Journal of immunology (1950) (01.04.2010)
Get full text
Journal Article
Skin Delivery of the JVRS-100 Immunostimulant with and without Fluzone using a Protrusion Array Device (PAD) Results in Potent Adaptive Immune Responses (78.34)
Chang, Stella, Gonzalez-Gonzalez, Emilio, Contag, Christopher H., Fairman, Jeff, Kaspar, Roger, Speaker, Tycho
Published in The Journal of immunology (1950) (01.04.2009)
Published in The Journal of immunology (1950) (01.04.2009)
Get full text
Journal Article