FRI0516 Paquinimod (ABR-215757), an Immunomodulatory Compound, Reduces Fibrosis in the Tight Skin-1 (TSK-1) Model for Systemic Sclerosis
Stenström, M., Carlsson Nyhlén, H., Nilsson, M., Eriksson, H., Törngren, M., Distler, J.H., Distler, O., Sparre, B., Tuvesson, H.
Published in Annals of the rheumatic diseases (01.06.2014)
Published in Annals of the rheumatic diseases (01.06.2014)
Get full text
Journal Article
FRI0496 An Open-Label Study to Evaluate Biomarkers and Safety in Systemic Sclerosis (SSC) Patients Treated with Paquinimod (ABR-215757)
Hesselstrand, R., Distler, J.H., Riemekasten, G., Törngren, M., Nyhlén, H.C., Stenström, M., Andersson, F., Eriksson, H., Sparre, B., Tuvesson, H., Distler, O.
Published in Annals of the rheumatic diseases (01.06.2014)
Published in Annals of the rheumatic diseases (01.06.2014)
Get full text
Journal Article
CYTOCHROME P450 3A4 IS THE MAJOR ENZYME RESPONSIBLE FOR THE METABOLISM OF LAQUINIMOD, A NOVEL IMMUNOMODULATOR
TUVESSON, Helén, HALLIN, Ingrid, PERSSON, Robert, SPARRE, Birgitta, GUNNARSSON, Per Olov, SEIDEGARD, Janeric
Published in Drug metabolism and disposition (01.06.2005)
Published in Drug metabolism and disposition (01.06.2005)
Get full text
Journal Article
In vitro metabolism and in vivo pharmacokinetics of quinoline 3-carboxamide derivatives in various species
Tuvesson, H, Hallin, I, Ellman, M, Sparre, B, Gunnarsson, P. O, Seidegård, J
Published in Xenobiotica (01.03.2005)
Published in Xenobiotica (01.03.2005)
Get full text
Journal Article
Pharmacokinetics, tolerability, and preliminary efficacy of paquinimod (ABR-215757), a new quinoline-3-carboxamide derivative: Studies in lupus-prone mice and a multicenter, randomized, double-blind, placebo-controlled, repeat-dose, dose-ranging study in patients with systemic lupus erythematosus
Bengtsson, Anders A., Sturfelt, Gunnar, Lood, Christian, Rönnblom, Lars, van Vollenhoven, Ronald F., Axelsson, Bengt, Sparre, Birgitta, Tuvesson, Helén, Öhman, Marie Wallén, Leanderson, Tomas
Published in Arthritis & rheumatology (Hoboken, N.J.) (01.05.2012)
Published in Arthritis & rheumatology (Hoboken, N.J.) (01.05.2012)
Get full text
Journal Article
The new orally active immunoregulator laquinimod (ABR-215062) effectively inhibits development and relapses of experimental autoimmune encephalomyelitis
Brunmark, Charlott, Runström, Anna, Ohlsson, Lennart, Sparre, Birgitta, Brodin, Thomas, Åström, Mikael, Hedlund, Gunnar
Published in Journal of neuroimmunology (01.09.2002)
Published in Journal of neuroimmunology (01.09.2002)
Get full text
Journal Article