Identification of diarylsulfonamides as agonists of the free fatty acid receptor 4 (FFA4/GPR120)
Sparks, Steven M., Chen, Grace, Collins, Jon L., Danger, Dana, Dock, Steven T., Jayawickreme, Channa, Jenkinson, Stephen, Laudeman, Christopher, Leesnitzer, M. Anthony, Liang, Xi, Maloney, Patrick, McCoy, David C., Moncol, David, Rash, Vincent, Rimele, Thomas, Vulimiri, Padmaja, Way, James M., Ross, Sean
Published in Bioorganic & medicinal chemistry letters (15.07.2014)
Published in Bioorganic & medicinal chemistry letters (15.07.2014)
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Journal Article
Lipid-mediated release of GLP-1 by mouse taste buds from circumvallate papillae: putative involvement of GPR120 and impact on taste sensitivity
Martin, Céline, Passilly-Degrace, Patricia, Chevrot, Michaël, Ancel, Déborah, Sparks, Steven M., Drucker, Daniel J., Besnard, Philippe
Published in Journal of lipid research (01.11.2012)
Published in Journal of lipid research (01.11.2012)
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Journal Article
Development of Highly Selective Pyrimidine-Based Aldosterone Synthase (CYP11B2) Inhibitors
Sparks, Steven M, Danger, Dana P, Hoekstra, William J, Leesnitzer, Tony, Schotzinger, Robert J, Yates, Christopher M, Becherer, J. David
Published in ACS medicinal chemistry letters (11.07.2019)
Published in ACS medicinal chemistry letters (11.07.2019)
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Journal Article
Exploration of phenylpropanoic acids as agonists of the free fatty acid receptor 4 (FFA4): Identification of an orally efficacious FFA4 agonist
Sparks, Steven M., Aquino, Christopher, Banker, Pierette, Collins, Jon L., Cowan, David, Diaz, Caroline, Dock, Steven T., Hertzog, Donald L., Liang, Xi, Swiger, Erin D., Yuen, Josephine, Chen, Grace, Jayawickreme, Channa, Moncol, David, Nystrom, Christopher, Rash, Vincent, Rimele, Thomas, Roller, Shane, Ross, Sean
Published in Bioorganic & medicinal chemistry letters (01.03.2017)
Published in Bioorganic & medicinal chemistry letters (01.03.2017)
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Journal Article
Identification of nonabsorbable inhibitors of the scavenger receptor-BI (SR-BI) for tissue-specific administration
Sparks, Steven M., Zhou, Huiqiang, Generaux, Claudia, Harston, Lindsey, Moncol, David, Jayawickreme, Channa, Parham, Janet, Condreay, Patrick, Rimele, Thomas
Published in Bioorganic & medicinal chemistry letters (15.04.2016)
Published in Bioorganic & medicinal chemistry letters (15.04.2016)
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Journal Article
Identification of potent, nonabsorbable agonists of the calcium-sensing receptor for GI-specific administration
Sparks, Steven M., Spearing, Paul K., Diaz, Caroline J., Cowan, David J., Jayawickreme, Channa, Chen, Grace, Rimele, Thomas J., Generaux, Claudia, Harston, Lindsey T., Roller, Shane G.
Published in Bioorganic & medicinal chemistry letters (15.10.2017)
Published in Bioorganic & medicinal chemistry letters (15.10.2017)
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Journal Article
The Type 2 Intramolecular Diels-Alder Reaction: Synthesis and Chemistry of Bridgehead Alkenes
Bear, Brian R., Sparks, Steven M., Shea, Kenneth J.
Published in Angewandte Chemie International Edition (02.03.2001)
Published in Angewandte Chemie International Edition (02.03.2001)
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Journal Article
인다졸계 화합물 및 관련된 사용 방법
DONG HANQING, WANG JING, ARAUJO ERIKA, SPARKS STEVEN M, BERLIN MICHAEL, ZHANG WEI
Year of Publication 26.12.2023
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Year of Publication 26.12.2023
Patent
Anthranilimide based glycogen phosphorylase inhibitors for the treatment of type 2 diabetes. Part 3: X-ray crystallographic characterization, core and urea optimization and in vivo efficacy
Thomson, Stephen A., Banker, Pierette, Bickett, D. Mark, Boucheron, Joyce A., Carter, H. Luke, Clancy, Daphne C., Cooper, Joel P., Dickerson, Scott H., Garrido, Dulce M., Nolte, Robert T., Peat, Andrew J., Sheckler, Lauren R., Sparks, Steven M., Tavares, Francis X., Wang, Liping, Wang, Tony Y., Weiel, James E.
Published in Bioorganic & medicinal chemistry letters (15.02.2009)
Published in Bioorganic & medicinal chemistry letters (15.02.2009)
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Journal Article
Phenoxyacetic acids as PPARδ partial agonists: Synthesis, optimization, and in vivo efficacy
Evans, Karen A., Shearer, Barry G., Wisnoski, David D., Shi, Dongchuan, Sparks, Steven M., Sternbach, Daniel D., Winegar, Deborah A., Billin, Andrew N., Britt, Christy, Way, James M., Epperly, Andrea H., Leesnitzer, Lisa M., Merrihew, Raymond V., Xu, Robert X., Lambert, Millard H., Jin, Jian
Published in Bioorganic & medicinal chemistry letters (15.04.2011)
Published in Bioorganic & medicinal chemistry letters (15.04.2011)
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Journal Article
Anthranilimide-based glycogen phosphorylase inhibitors for the treatment of Type 2 diabetes: 2. Optimization of serine and threonine ether amino acid residues
Sparks, Steven M., Banker, Pierette, Bickett, David M., Clancy, Daphne C., Dickerson, Scott H., Garrido, Dulce M., Golden, Pamela L., Peat, Andrew J., Sheckler, Lauren R., Tavares, Francis X., Thomson, Stephen A., Weiel, James E.
Published in Bioorganic & medicinal chemistry letters (01.02.2009)
Published in Bioorganic & medicinal chemistry letters (01.02.2009)
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Journal Article
Anthranilimide-based glycogen phosphorylase inhibitors for the treatment of type 2 diabetes: 1. Identification of 1-amino-1-cycloalkyl carboxylic acid headgroups
Sparks, Steven M., Banker, Pierette, Bickett, David M., Carter, H. Luke, Clancy, Daphne C., Dickerson, Scott H., Dwornik, Kate A., Garrido, Dulce M., Golden, Pamela L., Nolte, Robert T., Peat, Andrew J., Sheckler, Lauren R., Tavares, Francis X., Thomson, Stephen A., Wang, Liping, Weiel, James E.
Published in Bioorganic & medicinal chemistry letters (01.02.2009)
Published in Bioorganic & medicinal chemistry letters (01.02.2009)
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Journal Article