T Cell Receptor Cross-Reactivity between Similar Foreign and Self Peptides Influences Naive Cell Population Size and Autoimmunity
Nelson, Ryan W., Beisang, Daniel, Tubo, Noah J., Dileepan, Thamotharampillai, Wiesner, Darin L., Nielsen, Kirsten, Wüthrich, Marcel, Klein, Bruce S., Kotov, Dmitri I., Spanier, Justin A., Fife, Brian T., Moon, James J., Jenkins, Marc K.
Published in Immunity (Cambridge, Mass.) (20.01.2015)
Published in Immunity (Cambridge, Mass.) (20.01.2015)
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Tregs with an MHC class II peptide-specific chimeric antigen receptor prevent autoimmune diabetes in mice
Spanier, Justin A, Fung, Vivian, Wardell, Christine M, Alkhatib, Mohannad H, Chen, Yixin, Swanson, Linnea A, Dwyer, Alexander J, Weno, Matthew E, Silva, Nubia, Mitchell, Jason S, Orban, Paul C, Mojibian, Majid, Verchere, C Bruce, Fife, Brian T, Levings, Megan K
Published in The Journal of clinical investigation (15.09.2023)
Published in The Journal of clinical investigation (15.09.2023)
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Development of canine PD-1/PD-L1 specific monoclonal antibodies and amplification of canine T cell function
Choi, Jin Wook, Withers, Sita S, Chang, Hong, Spanier, Justin A, De La Trinidad, Victoria L, Panesar, Harmanpreet, Fife, Brian T, Sciammas, Roger, Sparger, Ellen E, Moore, Peter F, Kent, Michael S, Rebhun, Robert B, McSorley, Stephen J
Published in PloS one (02.07.2020)
Published in PloS one (02.07.2020)
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Programmed Death-1 Culls Peripheral Accumulation of High-Affinity Autoreactive CD4 T Cells to Protect against Autoimmunity
Jiang, Tony T., Martinov, Tijana, Xin, Lijun, Kinder, Jeremy M., Spanier, Justin A., Fife, Brian T., Way, Sing Sing
Published in Cell reports (Cambridge) (08.11.2016)
Published in Cell reports (Cambridge) (08.11.2016)
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Efficient generation of monoclonal antibodies against peptide in the context of MHCII using magnetic enrichment
Spanier, Justin A., Frederick, Daniel R., Taylor, Justin J., Heffernan, James R., Kotov, Dmitri I., Martinov, Tijana, Osum, Kevin C., Ruggiero, Jenna L., Rust, Blake J., Landry, Samuel J., Jenkins, Marc K., McLachlan, James B., Fife, Brian T.
Published in Nature communications (13.06.2016)
Published in Nature communications (13.06.2016)
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Editorial: Fresh Ideas, Foundational Experiments: Immunology and Diabetes
Spanier, Justin A, Tse, Hubert M, Horwitz, Marc S, Fife, Brian T
Published in Frontiers in endocrinology (Lausanne) (16.05.2019)
Published in Frontiers in endocrinology (Lausanne) (16.05.2019)
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T Cell Receptor Cross-Reactivity between Similar Foreign and Self Peptides Influences Naive Cell Population Size and Autoimmunity
Nelson, Ryan W., Beisang, Daniel, Tubo, Noah J., Dileepan, Thamotharampillai, Wiesner, Darin L., Nielsen, Kirsten, Wüthrich, Marcel, Klein, Bruce S., Kotov, Dmitri I., Spanier, Justin A., Fife, Brian T., Moon, James J., Jenkins, Marc K.
Published in Immunity (Cambridge, Mass.) (16.06.2015)
Published in Immunity (Cambridge, Mass.) (16.06.2015)
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Thymic regulatory T cells arise via two distinct developmental programs
Owen, David L., Mahmud, Shawn A., Sjaastad, Louisa E., Williams, Jason B., Spanier, Justin A., Simeonov, Dimitre R., Ruscher, Roland, Huang, Weishan, Proekt, Irina, Miller, Corey N., Hekim, Can, Jeschke, Jonathan C., Aggarwal, Praful, Broeckel, Ulrich, LaRue, Rebecca S., Henzler, Christine M., Alegre, Maria-Luisa, Anderson, Mark S., August, Avery, Marson, Alexander, Zheng, Ye, Williams, Calvin B., Farrar, Michael A.
Published in Nature immunology (01.02.2019)
Published in Nature immunology (01.02.2019)
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Vitamin D3 alters microglia immune activation by an IL-10 dependent SOCS3 mechanism
Boontanrart, Mandy, Hall, Samuel D, Spanier, Justin A, Hayes, Colleen E, Olson, Julie K
Published in Journal of neuroimmunology (15.03.2016)
Published in Journal of neuroimmunology (15.03.2016)
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Interferon-gamma drives programmed death-ligand 1 expression on islet β cells to limit T cell function during autoimmune diabetes
Osum, Kevin C., Burrack, Adam L., Martinov, Tijana, Sahli, Nathanael L., Mitchell, Jason S., Tucker, Christopher G., Pauken, Kristen E., Papas, Klearchos, Appakalai, Balamurugan, Spanier, Justin A., Fife, Brian T.
Published in Scientific reports (29.05.2018)
Published in Scientific reports (29.05.2018)
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Vitamin D3-mediated resistance to a multiple sclerosis model disease depends on myeloid cell 1,25-dihydroxyvitamin D3 synthesis and correlates with increased CD4+ T cell CTLA-4 expression
Spanier, Justin A., Nashold, Faye E., Nelson, Corwin D., Praska, Corinne E., Hayes, Colleen E.
Published in Journal of neuroimmunology (15.01.2020)
Published in Journal of neuroimmunology (15.01.2020)
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1,25-Dihydroxyvitamin D₃ acts directly on the T lymphocyte vitamin D receptor to inhibit experimental autoimmune encephalomyelitis
Mayne, Christopher G, Spanier, Justin A, Relland, Lance M, Williams, Calvin B, Hayes, Colleen E
Published in European journal of immunology (01.03.2011)
Published in European journal of immunology (01.03.2011)
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Vitamin D 3 -mediated resistance to a multiple sclerosis model disease depends on myeloid cell 1,25-dihydroxyvitamin D 3 synthesis and correlates with increased CD4 + T cell CTLA-4 expression
Spanier, Justin A, Nashold, Faye E, Nelson, Corwin D, Praska, Corinne E, Hayes, Colleen E
Published in Journal of neuroimmunology (15.01.2020)
Published in Journal of neuroimmunology (15.01.2020)
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Vitamin D and estrogen synergy in Vdr -expressing CD4+ T cells is essential to induce Helios+ FoxP3+ T cells and prevent autoimmune demyelinating disease
Spanier, Justin A, Nashold, Faye E, Mayne, Christopher G, Nelson, Corwin D, Hayes, Colleen E
Published in Journal of neuroimmunology (15.09.2015)
Published in Journal of neuroimmunology (15.09.2015)
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CD4+ T cells reactive to a hybrid peptide from insulin-chromogranin A adopt a distinct effector fate and are pathogenic in autoimmune diabetes
Mitchell, Jason S., Spanier, Justin A., Dwyer, Alexander J., Knutson, Todd P., Alkhatib, Mohannad H., Qian, Gina, Weno, Matthew E., Chen, Yixin, Shaheen, Zachary R., Tucker, Christopher G., Kangas, Takashi O., Morales, Milagros Silva, Silva, Nubia, Kaisho, Tsuneyasu, Farrar, Michael A., Fife, Brian T.
Published in Immunity (Cambridge, Mass.) (08.10.2024)
Published in Immunity (Cambridge, Mass.) (08.10.2024)
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Estrogen Controls Vitamin D3-Mediated Resistance to Experimental Autoimmune Encephalomyelitis by Controlling Vitamin D3 Metabolism and Receptor Expression
Nashold, Faye E, Spach, Karen M, Spanier, Justin A, Hayes, Colleen E
Published in The Journal of immunology (1950) (15.09.2009)
Published in The Journal of immunology (1950) (15.09.2009)
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Increased Effector Memory Insulin-Specific CD4 + T Cells Correlate With Insulin Autoantibodies in Patients With Recent-Onset Type 1 Diabetes
Spanier, Justin A, Sahli, Nathanael L, Wilson, Joseph C, Martinov, Tijana, Dileepan, Thamotharampillai, Burrack, Adam L, Finger, Erik B, Blazar, Bruce R, Michels, Aaron W, Moran, Antoinette, Jenkins, Marc K, Fife, Brian T
Published in Diabetes (New York, N.Y.) (01.12.2017)
Published in Diabetes (New York, N.Y.) (01.12.2017)
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Programmed Death-1 Restrains the Germinal Center in Type 1 Diabetes
Martinov, Tijana, Swanson, Linnea A, Breed, Elise R, Tucker, Christopher G, Dwyer, Alexander J, Johnson, Jenna K, Mitchell, Jason S, Sahli, Nathanael L, Wilson, Joseph C, Singh, Lovejot M, Hogquist, Kristin A, Spanier, Justin A, Fife, Brian T
Published in The Journal of immunology (1950) (15.08.2019)
Published in The Journal of immunology (1950) (15.08.2019)
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Cutting edge: identification of autoreactive CD4+ and CD8+ T cell subsets resistant to PD-1 pathway blockade
Pauken, Kristen E, Nelson, Christine E, Martinov, Tijana, Spanier, Justin A, Heffernan, James R, Sahli, Nathanael L, Quarnstrom, Clare F, Osum, Kevin C, Schenkel, Jason M, Jenkins, Marc K, Blazar, Bruce R, Vezys, Vaiva, Fife, Brian T
Published in The Journal of immunology (1950) (15.04.2015)
Published in The Journal of immunology (1950) (15.04.2015)
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Cutting Edge: Dual TCRα Expression Poses an Autoimmune Hazard by Limiting Regulatory T Cell Generation
Schuldt, Nathaniel J, Auger, Jennifer L, Spanier, Justin A, Martinov, Tijana, Breed, Elise R, Fife, Brian T, Hogquist, Kristin A, Binstadt, Bryce A
Published in The Journal of immunology (1950) (01.07.2017)
Published in The Journal of immunology (1950) (01.07.2017)
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