The Staphylococcal Toxin Panton-Valentine Leukocidin Targets Human C5a Receptors
Spaan, András N., Henry, Thomas, van Rooijen, Willemien J.M., Perret, Magali, Badiou, Cédric, Aerts, Piet C., Kemmink, Johan, de Haas, Carla J.C., van Kessel, Kok P.M., Vandenesch, François, Lina, Gérard, van Strijp, Jos A.G.
Published in Cell host & microbe (15.05.2013)
Published in Cell host & microbe (15.05.2013)
Get full text
Journal Article
Phagocytosis escape by a Staphylococcus aureus protein that connects complement and coagulation proteins at the bacterial surface
Ko, Ya-Ping, Kuipers, Annemarie, Freitag, Claudia M, Jongerius, Ilse, Medina, Eva, van Rooijen, Willemien J, Spaan, András N, van Kessel, Kok P M, Höök, Magnus, Rooijakkers, Suzan H M
Published in PLoS pathogens (01.12.2013)
Published in PLoS pathogens (01.12.2013)
Get full text
Journal Article
Multibatch Cytometry Data Integration for Optimal Immunophenotyping
Ogishi, Masato, Yang, Rui, Gruber, Conor, Zhang, Peng, Pelham, Simon J, Spaan, András N, Rosain, Jérémie, Chbihi, Marwa, Han, Ji Eun, Rao, V Koneti, Kainulainen, Leena, Bustamante, Jacinta, Boisson, Bertrand, Bogunovic, Dusan, Boisson-Dupuis, Stéphanie, Casanova, Jean-Laurent
Published in The Journal of immunology (1950) (01.01.2021)
Published in The Journal of immunology (1950) (01.01.2021)
Get full text
Journal Article
Staphylococcus aureus Targets the Duffy Antigen Receptor for Chemokines (DARC) to Lyse Erythrocytes
Spaan, András N., Reyes-Robles, Tamara, Badiou, Cédric, Cochet, Sylvie, Boguslawski, Kristina M., Yoong, Pauline, Day, Christopher J., de Haas, Carla J.C., van Kessel, Kok P.M., Vandenesch, François, Jennings, Michael P., Le Van Kim, Caroline, Colin, Yves, van Strijp, Jos A.G., Henry, Thomas, Torres, Victor J.
Published in Cell host & microbe (09.09.2015)
Published in Cell host & microbe (09.09.2015)
Get full text
Journal Article
Human STAT3 variants underlie autosomal dominant hyper-IgE syndrome by negative dominance
Asano, Takaki, Khourieh, Joëlle, Zhang, Peng, Rapaport, Franck, Spaan, András N, Li, Juan, Lei, Wei-Te, Pelham, Simon J, Hum, David, Chrabieh, Maya, Han, Ji Eun, Guérin, Antoine, Mackie, Joseph, Gupta, Sudhir, Saikia, Biman, Baghdadi, Jamila E I, Fadil, Ilham, Bousfiha, Aziz, Habib, Tanwir, Marr, Nico, Ganeshanandan, Luckshman, Peake, Jane, Droney, Luke, Williams, Andrew, Celmeli, Fatih, Hatipoglu, Nevin, Ozcelik, Tayfun, Picard, Capucine, Abel, Laurent, Tangye, Stuart G, Boisson-Dupuis, Stéphanie, Zhang, Qian, Puel, Anne, Béziat, Vivien, Casanova, Jean-Laurent, Boisson, Bertrand
Published in The Journal of experimental medicine (02.08.2021)
Published in The Journal of experimental medicine (02.08.2021)
Get full text
Journal Article
The staphylococcal toxins γ-haemolysin AB and CB differentially target phagocytes by employing specific chemokine receptors
Spaan, András N., Vrieling, Manouk, Wallet, Pierre, Badiou, Cédric, Reyes-Robles, Tamara, Ohneck, Elizabeth A., Benito, Yvonne, de Haas, Carla J. C., Day, Christopher J., Jennings, Michael P., Lina, Gérard, Vandenesch, François, van Kessel, Kok P. M., Torres, Victor J., van Strijp, Jos A. G., Henry, Thomas
Published in Nature communications (11.11.2014)
Published in Nature communications (11.11.2014)
Get full text
Journal Article
Differential Interaction of the Staphylococcal Toxins Panton-Valentine Leukocidin and γ-Hemolysin CB with Human C5a Receptors
Spaan, András N, Schiepers, Ariën, de Haas, Carla J C, van Hooijdonk, Davy D J J, Badiou, Cédric, Contamin, Hugues, Vandenesch, François, Lina, Gérard, Gerard, Norma P, Gerard, Craig, van Kessel, Kok P M, Henry, Thomas, van Strijp, Jos A G
Published in The Journal of immunology (1950) (01.08.2015)
Published in The Journal of immunology (1950) (01.08.2015)
Get full text
Journal Article
Biochemically deleterious human NFKB1 variants underlie an autosomal dominant form of common variable immunodeficiency
Li, Juan, Lei, Wei-Te, Zhang, Peng, Rapaport, Franck, Seeleuthner, Yoann, Lyu, Bingnan, Asano, Takaki, Rosain, Jérémie, Hammadi, Boualem, Zhang, Yu, Pelham, Simon J, Spaan, András N, Migaud, Mélanie, Hum, David, Bigio, Benedetta, Chrabieh, Maya, Béziat, Vivien, Bustamante, Jacinta, Zhang, Shen-Ying, Jouanguy, Emmanuelle, Boisson-Dupuis, Stephanie, El Baghdadi, Jamila, Aimanianda, Vishukumar, Thoma, Katharina, Fliegauf, Manfred, Grimbacher, Bodo, Korganow, Anne-Sophie, Saunders, Carol, Rao, V Koneti, Uzel, Gulbu, Freeman, Alexandra F, Holland, Steven M, Su, Helen C, Cunningham-Rundles, Charlotte, Fieschi, Claire, Abel, Laurent, Puel, Anne, Cobat, Aurélie, Casanova, Jean-Laurent, Zhang, Qian, Boisson, Bertrand
Published in The Journal of experimental medicine (01.11.2021)
Published in The Journal of experimental medicine (01.11.2021)
Get full text
Journal Article
OTULIN Haploinsufficiency-Related Fasciitis and Skin Necrosis Treated by TNF Inhibition
Arts, Rob J. W., van der Linden, Tristan J., van der Made, Caspar I., Hendriks, Marianne M. C., van der Heijden, Wouter A., de Mast, Quirijn, Schuurs-Hoeijmakers, Janneke H. M., Simons, Annet, Spaan, András N., Mulders-Manders, Catharina M., van de Veerdonk, Frank L.
Published in Journal of clinical immunology (01.01.2024)
Published in Journal of clinical immunology (01.01.2024)
Get full text
Journal Article
Host-Receptor Post-Translational Modifications Refine Staphylococcal Leukocidin Cytotoxicity
Tromp, Angelino T, Van Gent, Michiel, Jansen, Joris P, Scheepmaker, Lisette M, Velthuizen, Anneroos, De Haas, Carla J C, Van Kessel, Kok P M, Bardoel, Bart W, Boettcher, Michael, McManus, Michael T, Van Strijp, Jos A G, Lebbink, Robert Jan, Haas, Pieter-Jan A, Spaan, András N
Published in Toxins (06.02.2020)
Published in Toxins (06.02.2020)
Get full text
Journal Article
Pre-existing antibody-mediated adverse effects prevent the clinical development of a bacterial anti-inflammatory protein
Tromp, Angelino T, Zhao, Yuxi, Jongerius, Ilse, Heezius, Erik C J M, Abrial, Pauline, Ruyken, Maartje, van Strijp, Jos A G, de Haas, Carla J C, Spaan, András N, van Kessel, Kok P M, Henry, Thomas, Haas, Pieter-Jan A
Published in Disease models & mechanisms (28.09.2020)
Published in Disease models & mechanisms (28.09.2020)
Get full text
Journal Article
Human CD45 is an F-component-specific receptor for the staphylococcal toxin Panton–Valentine leukocidin
Tromp, Angelino T., Van Gent, Michiel, Abrial, Pauline, Martin, Amandine, Jansen, Joris P., De Haas, Carla J. C., Van Kessel, Kok P. M., Bardoel, Bart W., Kruse, Elisabeth, Bourdonnay, Emilie, Boettcher, Michael, McManus, Michael T., Day, Christopher J., Jennings, Michael P., Lina, Gérard, Vandenesch, François, Van Strijp, Jos A. G., Lebbink, Robert Jan, Haas, Pieter-Jan A., Henry, Thomas, Spaan, András N.
Published in Nature microbiology (01.06.2018)
Published in Nature microbiology (01.06.2018)
Get full text
Journal Article
Leukocidins: staphylococcal bi-component pore-forming toxins find their receptors
Spaan, András N., van Strijp, Jos A. G., Torres, Victor J.
Published in Nature reviews. Microbiology (01.07.2017)
Published in Nature reviews. Microbiology (01.07.2017)
Get full text
Journal Article
Neutrophils versus Staphylococcus aureus: a biological tug of war
Spaan, András N, Surewaard, Bas G J, Nijland, Reindert, van Strijp, Jos A G
Published in Annual review of microbiology (01.01.2013)
Published in Annual review of microbiology (01.01.2013)
Get more information
Journal Article
Autoantibodies Neutralizing Type I IFNs in the Bronchoalveolar Lavage of at Least 10% of Patients During Life-Threatening COVID-19 Pneumonia
Philippot, Quentin, Fekkar, Arnaud, Gervais, Adrian, Le Voyer, Tom, Boers, Leonoor S., Conil, Clément, Bizien, Lucy, de Brabander, Justin, Duitman, Jan Willem, Romano, Alessia, Rosain, Jérémie, Blaize, Marion, Migaud, Mélanie, Jeljeli, Maxime, Hammadi, Boualem, Desmons, Aurore, Marchal, Astrid, Mayaux, Julien, Zhang, Qian, Jouanguy, Emmanuelle, Borie, Raphael, Crestani, Bruno, Luyt, Charles Edouard, Adle-Biassette, Homa, Sene, Damien, Megarbane, Bruno, Cobat, Aurélie, Bastard, Paul, Bos, Lieuwe D. J., Casanova, Jean-Laurent, Puel, Anne
Published in Journal of clinical immunology (01.08.2023)
Published in Journal of clinical immunology (01.08.2023)
Get full text
Journal Article
Autoimmune Lymphoproliferative Syndrome Presenting with Invasive Streptococcus pneumoniae Infection
Oksenhendler, Eric, Spaan, András N., Neven, Bénédicte, Stolzenberg, Marie-Claude, Fusaro, Mathieu, Casanova, Jean-Laurent, Rieux-Laucat, Frédéric, Boisson, Bertrand, Magérus, Aude
Published in Journal of clinical immunology (01.04.2020)
Published in Journal of clinical immunology (01.04.2020)
Get full text
Journal Article
Identification of the human mitochondrial FAD transporter and its potential role in multiple acyl-CoA dehydrogenase deficiency
Spaan, András N., IJlst, Lodewijk, van Roermund, Carlo W.T., Wijburg, Frits A., Wanders, Ronald J.A., Waterham, Hans R.
Published in Molecular genetics and metabolism (01.12.2005)
Published in Molecular genetics and metabolism (01.12.2005)
Get full text
Journal Article
Publisher Correction: Human CD45 is an F-component-specific receptor for the staphylococcal toxin Panton–Valentine leukocidin
Tromp, Angelino T., Van Gent, Michiel, Abrial, Pauline, Martin, Amandine, Jansen, Joris P., De Haas, Carla J. C., Van Kessel, Kok P. M., Bardoel, Bart W., Kruse, Elisabeth, Bourdonnay, Emilie, Boettcher, Michael, McManus, Michael T., Day, Christopher J., Jennings, Michael P., Lina, Gérard, Vandenesch, François, Van Strijp, Jos A. G., Lebbink, Robert Jan, Haas, Pieter-Jan A., Henry, Thomas, Spaan, András N.
Published in Nature microbiology (01.10.2018)
Published in Nature microbiology (01.10.2018)
Get full text
Journal Article