Cross-strand binding of TFAM to a single mtDNA molecule forms the mitochondrial nucleoid
Kukat, Christian, Davies, Karen M., Wurm, Christian A., Spåhr, Henrik, Bonekamp, Nina A., Kühl, Inge, Joos, Friederike, Polosa, Paola Loguercio, Park, Chan Bae, Posse, Viktor, Falkenberg, Maria, Jakobs, Stefan, Kühlbrandt, Werner, Larsson, Nils-Göran
Published in Proceedings of the National Academy of Sciences - PNAS (08.09.2015)
Published in Proceedings of the National Academy of Sciences - PNAS (08.09.2015)
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SLIRP Regulates the Rate of Mitochondrial Protein Synthesis and Protects LRPPRC from Degradation
Lagouge, Marie, Mourier, Arnaud, Lee, Hyun Ju, Spåhr, Henrik, Wai, Timothy, Kukat, Christian, Silva Ramos, Eduardo, Motori, Elisa, Busch, Jakob D, Siira, Stefan, Kremmer, Elisabeth, Filipovska, Aleksandra, Larsson, Nils-Göran
Published in PLoS genetics (01.08.2015)
Published in PLoS genetics (01.08.2015)
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ANGEL2 phosphatase activity is required for non-canonical mitochondrial RNA processing
Clemente, Paula, Calvo-Garrido, Javier, Pearce, Sarah F, Schober, Florian A, Shigematsu, Megumi, Siira, Stefan J, Laine, Isabelle, Spåhr, Henrik, Steinmetzger, Christian, Petzold, Katja, Kirino, Yohei, Wibom, Rolf, Rackham, Oliver, Filipovska, Aleksandra, Rorbach, Joanna, Freyer, Christoph, Wredenberg, Anna
Published in Nature communications (30.09.2022)
Published in Nature communications (30.09.2022)
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Journal Article
MTERF3 regulates mitochondrial ribosome biogenesis in invertebrates and mammals
Wredenberg, Anna, Lagouge, Marie, Bratic, Ana, Metodiev, Metodi D, Spåhr, Henrik, Mourier, Arnaud, Freyer, Christoph, Ruzzenente, Benedetta, Tain, Luke, Grönke, Sebastian, Baggio, Francesca, Kukat, Christian, Kremmer, Elisabeth, Wibom, Rolf, Polosa, Paola Loguercio, Habermann, Bianca, Partridge, Linda, Park, Chan Bae, Larsson, Nils-Göran
Published in PLoS genetics (01.01.2013)
Published in PLoS genetics (01.01.2013)
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Journal Article
Dinucleotide Degradation by REXO2 Maintains Promoter Specificity in Mammalian Mitochondria
Nicholls, Thomas J., Spåhr, Henrik, Jiang, Shan, Siira, Stefan J., Koolmeister, Camilla, Sharma, Sushma, Kauppila, Johanna H.K., Jiang, Min, Kaever, Volkhard, Rackham, Oliver, Chabes, Andrei, Falkenberg, Maria, Filipovska, Aleksandra, Larsson, Nils-Göran, Gustafsson, Claes M.
Published in Molecular cell (05.12.2019)
Published in Molecular cell (05.12.2019)
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A human mitochondrial poly(A) polymerase mutation reveals the complexities of post-transcriptional mitochondrial gene expression
Wilson, William C, Hornig-Do, Hue-Tran, Bruni, Francesco, Chang, Jeong Ho, Jourdain, Alexis A, Martinou, Jean-Claude, Falkenberg, Maria, Spåhr, Henrik, Larsson, Nils-Göran, Lewis, Richard J, Hewitt, Lorraine, Baslé, Arnaud, Cross, Harold E, Tong, Liang, Lebel, Robert R, Crosby, Andrew H, Chrzanowska-Lightowlers, Zofia M A, Lightowlers, Robert N
Published in Human molecular genetics (01.12.2014)
Published in Human molecular genetics (01.12.2014)
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Journal Article
Schizosacharomyces pombe RNA polymerase II at 3.6-Å resolution
Spåhr, Henrik, Calero, Guillermo, Bushnell, David A, Kornberg, Roger D
Published in Proceedings of the National Academy of Sciences - PNAS (09.06.2009)
Published in Proceedings of the National Academy of Sciences - PNAS (09.06.2009)
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Journal Article
Distinct pre-initiation steps in human mitochondrial translation
Khawaja, Anas, Itoh, Yuzuru, Remes, Cristina, Spåhr, Henrik, Yukhnovets, Olessya, Höfig, Henning, Amunts, Alexey, Rorbach, Joanna
Published in Nature communications (10.06.2020)
Published in Nature communications (10.06.2020)
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Journal Article
Super-resolution microscopy reveals that mammalian mitochondrial nucleoids have a uniform size and frequently contain a single copy of mtDNA
Kukat, Christian, Wurm, Christian A, Spåhr, Henrik, Falkenberg, Maria, Larsson, Nils-Göran, Jakobs, Stefan
Published in Proceedings of the National Academy of Sciences - PNAS (16.08.2011)
Published in Proceedings of the National Academy of Sciences - PNAS (16.08.2011)
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Journal Article
LRPPRC-mediated folding of the mitochondrial transcriptome
Siira, Stefan J, Spåhr, Henrik, Shearwood, Anne-Marie J, Ruzzenente, Benedetta, Larsson, Nils-Göran, Rackham, Oliver, Filipovska, Aleksandra
Published in Nature communications (16.11.2017)
Published in Nature communications (16.11.2017)
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Journal Article
NSUN4 is a dual function mitochondrial protein required for both methylation of 12S rRNA and coordination of mitoribosomal assembly
Metodiev, Metodi Dimitrov, Spåhr, Henrik, Loguercio Polosa, Paola, Meharg, Caroline, Becker, Christian, Altmueller, Janine, Habermann, Bianca, Larsson, Nils-Göran, Ruzzenente, Benedetta
Published in PLoS genetics (01.02.2014)
Published in PLoS genetics (01.02.2014)
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Journal Article
Human mitochondria require mtRF1 for translation termination at non-canonical stop codons
Krüger, Annika, Remes, Cristina, Shiriaev, Dmitrii Igorevich, Liu, Yong, Spåhr, Henrik, Wibom, Rolf, Atanassov, Ilian, Nguyen, Minh Duc, Cooperman, Barry S, Rorbach, Joanna
Published in Nature communications (03.01.2023)
Published in Nature communications (03.01.2023)
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Journal Article
Loss of the RNA-binding protein TACO1 causes late-onset mitochondrial dysfunction in mice
Richman, Tara R, Spåhr, Henrik, Ermer, Judith A, Davies, Stefan M K, Viola, Helena M, Bates, Kristyn A, Papadimitriou, John, Hool, Livia C, Rodger, Jennifer, Larsson, Nils-Göran, Rackham, Oliver, Filipovska, Aleksandra
Published in Nature communications (20.06.2016)
Published in Nature communications (20.06.2016)
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Journal Article
Structure of the human MTERF4-NSUN4 protein complex that regulates mitochondrial ribosome biogenesis
Spåhr, Henrik, Habermann, Bianca, Gustafsson, Claes M., Larsson, Nils-Göran, Hallberg, B. Martin
Published in Proceedings of the National Academy of Sciences - PNAS (18.09.2012)
Published in Proceedings of the National Academy of Sciences - PNAS (18.09.2012)
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Journal Article
C6orf203 is an RNA-binding protein involved in mitochondrial protein synthesis
Gopalakrishna, Shreekara, Pearce, Sarah F, Dinan, Adam M, Schober, Florian A, Cipullo, Miriam, Spåhr, Henrik, Khawaja, Anas, Maffezzini, Camilla, Freyer, Christoph, Wredenberg, Anna, Atanassov, Ilian, Firth, Andrew E, Rorbach, Joanna
Published in Nucleic acids research (26.09.2019)
Published in Nucleic acids research (26.09.2019)
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Journal Article
Crystal Structure of a Transcribing RNA Polymerase II Complex Reveals a Complete Transcription Bubble
Barnes, Christopher O., Calero, Monica, Malik, Indranil, Graham, Brian W., Spahr, Henrik, Lin, Guowu, Cohen, Aina E., Brown, Ian S., Zhang, Qiangmin, Pullara, Filippo, Trakselis, Michael A., Kaplan, Craig D., Calero, Guillermo
Published in Molecular cell (16.07.2015)
Published in Molecular cell (16.07.2015)
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Journal Article
SLIRP stabilizes LRPPRC via an RRM-PPR protein interface
Spåhr, Henrik, Rozanska, Agata, Li, Xinping, Atanassov, Ilian, Lightowlers, Robert N, Chrzanowska-Lightowlers, Zofia M A, Rackham, Oliver, Larsson, Nils-Göran
Published in Nucleic acids research (19.08.2016)
Published in Nucleic acids research (19.08.2016)
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Journal Article
Disease causing mutation (P178L) in mitochondrial transcription factor A results in impaired mitochondrial transcription initiation
Mehmedović, Majda, Martucci, Martial, Spåhr, Henrik, Ishak, Layal, Mishra, Anup, Sanchez-Sandoval, Maria Eugenia, Pardo-Hernández, Carlos, Peter, Bradley, van den Wildenberg, Siet M., Falkenberg, Maria, Farge, Geraldine
Published in Biochimica et biophysica acta. Molecular basis of disease (01.10.2022)
Published in Biochimica et biophysica acta. Molecular basis of disease (01.10.2022)
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