EXPRESSION PROFILE OF MOLECULAR CIRCADIAN CLOCK GENES PREDICTS RISK STRATIFICATION IN ACUTE MYELOID LEUKEMIA
Brandão, M, Lima, SCG, Covas, DT, Souza, LEB
Published in Hematology, Transfusion and Cell Therapy (01.10.2023)
Published in Hematology, Transfusion and Cell Therapy (01.10.2023)
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Journal Article
PARP AND PARG INHIBITION SELECTIVELY IMPAIR METABOLISM OF B-ALL CELL LINES AND INDUCE CYTOTOXICITY THROUGH DISTINCT CELL-DEATH PATHWAYS
Machado, CB, Esteves, KS, Lima, SCG, Furtado, IP, Brandão, M, Pessoa, FMCP, Nogueira, BMD, Moraes, MEA, Souza, LEB, Moreira-Nunes, CFA
Published in Hematology, Transfusion and Cell Therapy (01.10.2024)
Published in Hematology, Transfusion and Cell Therapy (01.10.2024)
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Journal Article
PRODUCTION OF “UNIVERSAL” CHIMERIC ANTIGEN RECEPTOR (CAR) T CELLS THROUGH A HIGHLY EFFICIENT CRISPR/CAS9-INDUCED KNOCKOUT OF THE ENDOGENOUS TRAC GENE
Lima, SCG, Rossetti, R, Quadros, AU, Esteves, KS, Furtado, IP, Fantacini, DMC, Silveira, RM, Covas, DT, Souza, LEB
Published in Hematology, Transfusion and Cell Therapy (01.10.2023)
Published in Hematology, Transfusion and Cell Therapy (01.10.2023)
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Journal Article
EMPOWERING CAR-T CELL THERAPY: GITRL COSTIMULATION FOR ENHANCED ANTITUMOR RESPONSE AND IMMUNOSSUPPRESSION RESISTANCE IN SOLID TUMORS
Furtado, IP, Silveira, RM, Rossetti, R, Fantacini, DMC, Lima, SCG, Tsyrenov, L, Shiku, H, Souza, LEB, Covas, DT
Published in Hematology, Transfusion and Cell Therapy (01.10.2023)
Published in Hematology, Transfusion and Cell Therapy (01.10.2023)
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Journal Article
GENETICALLY ENGINEERED T CELLS EXPRESSING HIGH AFFINITY TCR ANTI-NY-ESO-1:HLA-A02 ARE ABLE TO CONTROL SOLID TUMOR GROWTH IN VIVO
Rossetti, R, Lima, SCG, Fantacini, DMC, Carvalho, JV, Furtado, IP, Silveira, RM, Tsyrenov, L, Shiku, H, Souza, LEB, Covas, DT
Published in Hematology, Transfusion and Cell Therapy (01.10.2023)
Published in Hematology, Transfusion and Cell Therapy (01.10.2023)
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Journal Article
PARP1 IS DIFFERENTIALLY EXPRESSED IN BCR-ABL P190+ ALL PATIENT SAMPLES AND TARGETING PARP INHIBITION INDUCES CELL DEATH COMPARABLE TO THAT OF TYROSINE-KINASE GOLDEN STANDARD IN PRE-CLINICAL MODELS
Machado, CB, Ferreira, WAS, Pessoa, FMCP, Mell-Júnior, FAR, Seabra, AD, Ribeiro, RM, Morae-Filho, MO, Moraes, MEA, Souza, LEB, Moreir-Nunes, CFA
Published in Hematology, Transfusion and Cell Therapy (01.10.2023)
Published in Hematology, Transfusion and Cell Therapy (01.10.2023)
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Journal Article
CHARACTERIZATION OF A NOVEL ANTI-CD19 CAR CONSTRUCT CO-EXPRESSING THE COSTIMULATORY MOLECULE GITRL
Fantacini, DMC, Lima, SCG, Rossetti, R, Furtado, IP, Silveira, RM, Tsyrenov, L, Shiku, H, Covas, DT, Souza, LEB
Published in Hematology, Transfusion and Cell Therapy (01.10.2023)
Published in Hematology, Transfusion and Cell Therapy (01.10.2023)
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Journal Article
A NOVEL SYNTHETIC AND RECOMBINANT GLUCOCEREBROSIDASE FOR GAUCHER DISEASE: IN SILICO MOLECULAR EVOLUTION AND GENE THERAPY APPROACHES TO ENHANCE ENZYME ACTIVITY
Figueiredo, LLS, Souza, LEB, Orellana, MD, Covas, DT, Lichtenstein, F, Siciliano, V, Abraham, KJ, Weiss, R, Gerson, SL, Fontes, AM
Published in Hematology, Transfusion and Cell Therapy (01.10.2023)
Published in Hematology, Transfusion and Cell Therapy (01.10.2023)
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Journal Article
ESTABLISHMENT OF A CRISPR/CAS9-BASED GENOME EDITING PLATFORM FOR THE GENERATION OF AN OFF-THE-SHELF ALLOGENEIC CAR-T CELL MODEL
Lima, SCG, Brand, H, Batista, LC, Fantacini, DMC, Coelho, MGB, Castro, FA, Covas, DT, Souza, LEB
Published in Hematology, Transfusion and Cell Therapy (01.10.2021)
Published in Hematology, Transfusion and Cell Therapy (01.10.2021)
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Journal Article
CÉLULAS CAR-T EXPRESSANDO UMA NOVA CONSTRUÇÃO CONTRA O ANTÍGENO INTRACELULAR MAGE-A4 INDUZEM REGRESSÃO TUMORAL COMPLETA EM MODELO DE MIELOMA MÚLTIPLO
Silveira, RM, Furtado, IP, Fantacini, DMC, Rossetti, R, Ferreira, AUQ, Tsyrenov, L, Shiku, H, Covas, DT, Souza, LEB
Published in Hematology, Transfusion and Cell Therapy (01.10.2023)
Published in Hematology, Transfusion and Cell Therapy (01.10.2023)
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Journal Article
EVALUATION OF ANTI-CD19 CAR-T CELL PERSISTENCE AND EFFICACY USING A DEVELOPED MULTIPARAMETRIC FLOW CYTOMETRY AND QPCR TRACKING PLATFORM FOR PRECLINICAL AND CLINICAL STUDIES
Batista, LC, Brand, H, Fantacini, DMC, Covas, DT, Souza, LEB
Published in Cytotherapy (Oxford, England) (01.04.2021)
Published in Cytotherapy (Oxford, England) (01.04.2021)
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Journal Article
DEVELOPMENT OF CRISPR/CAS9-BASED GENOME EDITING PLATFORM FOR THE GENERATION OF ALLOGENEIC CAR-T CELLS
Lima, SCG, Brand, H, Batista, LC, Fantacini, DMC, Coelho, MGB, Castro, FA, Covas, DT, Souza, LEB
Published in Cytotherapy (Oxford, England) (01.04.2021)
Published in Cytotherapy (Oxford, England) (01.04.2021)
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Journal Article
OPTIMIZED PROTOCOLS OF EXPANSION OF PERIPHERAL BLOOD-DERIVED δT-CELLS FOR THE ESTABLISHMENT OF AN OFF-THE-SHELF ADVANCED CELL THERAPY AGAINST CANCER
Fantacini, DMC, Lima, SCG, Rossetti, R, Furtado, IP, Silveira, RM, Covas, DT, Souza, LEB
Published in Hematology, Transfusion and Cell Therapy (01.10.2022)
Published in Hematology, Transfusion and Cell Therapy (01.10.2022)
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Journal Article
T CELLS ENGINEERED TO EXPRESS A CAR ANTI-GD2 AND THE COSTIMULATORY MOLECULE GITRL ERADICATE GLIOBLASTOMA CELLS AND ARE IFNY PRODUCERS
Furtado, IP, Silveira, RM, Brand, H, Rossetti, R, Fantacini, DMC, Souza, LEB, Covas, DT
Published in Hematology, Transfusion and Cell Therapy (01.10.2022)
Published in Hematology, Transfusion and Cell Therapy (01.10.2022)
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Journal Article
GENERATION OF T LYMPHOCYTES EXPRESSING ENGINEERED T CELL RECEPTOR TARGETING THE NY-ESO-1 TUMOR ANTIGEN USING A NEW GENETIC CONSTRUCT
Rossetti, R, Furtado, IP, Fantacini, DMC, Silveira, RM, Lima, SCG, Brand, H, Souza, LEB, Covas, DT
Published in Hematology, Transfusion and Cell Therapy (01.10.2022)
Published in Hematology, Transfusion and Cell Therapy (01.10.2022)
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