Neuronal hyperexcitability and ion channel dysfunction in CDKL5-deficiency patient iPSC-derived cortical organoids
Wu, Wei, Yao, Hang, Negraes, Priscilla D., Wang, Juan, Trujillo, Cleber A., de Souza, Janaina S., Muotri, Alysson R., Haddad, Gabriel G.
Published in Neurobiology of disease (01.11.2022)
Published in Neurobiology of disease (01.11.2022)
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Journal Article
Transcription Factor 4 loss-of-function is associated with deficits in progenitor proliferation and cortical neuron content
Papes, Fabio, Camargo, Antonio P., de Souza, Janaina S., Carvalho, Vinicius M. A., Szeto, Ryan A., LaMontagne, Erin, Teixeira, José R., Avansini, Simoni H., Sánchez-Sánchez, Sandra M., Nakahara, Thiago S., Santo, Carolina N., Wu, Wei, Yao, Hang, Araújo, Barbara M. P., Velho, Paulo E. N. F., Haddad, Gabriel G., Muotri, Alysson R.
Published in Nature communications (02.05.2022)
Published in Nature communications (02.05.2022)
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Journal Article
Unveiling the Angiotensin-(1–7) Actions on the Urinary Bladder in Female Rats
Lamy, Gustavo B., Cafarchio, Eduardo M., do Vale, Bárbara, Antonio, Bruno B., Venancio, Daniel P., de Souza, Janaina S., Maciel, Rui M., Giannocco, Gisele, Silva Neto, Artur F., Oyama, Lila M., Aronsson, Patrik, Sato, Monica A.
Published in Frontiers in physiology (19.07.2022)
Published in Frontiers in physiology (19.07.2022)
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Journal Article
Embryonic origin of two ASD subtypes of social symptom severity: the larger the brain cortical organoid size, the more severe the social symptoms
Courchesne, Eric, Taluja, Vani, Nazari, Sanaz, Aamodt, Caitlin M, Pierce, Karen, Duan, Kuaikuai, Stophaeros, Sunny, Lopez, Linda, Barnes, Cynthia Carter, Troxel, Jaden, Campbell, Kathleen, Wang, Tianyun, Hoekzema, Kendra, Eichler, Evan E, Nani, Joao V, Pontes, Wirla, Sanchez, Sandra Sanchez, Lombardo, Michael V, de Souza, Janaina S, Hayashi, Mirian A F, Muotri, Alysson R
Published in Molecular autism (25.05.2024)
Published in Molecular autism (25.05.2024)
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Journal Article
Lateral Preoptic Area Neurons Activated by Angiotensin-(1–7) Increase Intravesical Pressure: A Novel Feature in Central Micturition Control
Lamy, Gustavo B., Cafarchio, Eduardo M., do Vale, Bárbara, Antonio, Bruno B., Venancio, Daniel P., de Souza, Janaina S., Maciel, Rui M., Giannocco, Gisele, Aronsson, Patrik, Sato, Monica A.
Published in Frontiers in physiology (12.07.2021)
Published in Frontiers in physiology (12.07.2021)
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Journal Article
Oxytocin Reduces Intravesical Pressure in Anesthetized Female Rats: Action on Oxytocin Receptors of the Urinary Bladder
Cafarchio, Eduardo M, da Silva, Luiz A, Auresco, Luciana C, Rodart, Itatiana F, de Souza, Janaina S, Antonio, Bruno B, Venancio, Daniel P, Maifrino, Laura B M, Maciel, Rui M B, Giannocco, Gisele, Aronsson, Patrik, Sato, Monica A
Published in Frontiers in physiology (06.05.2020)
Published in Frontiers in physiology (06.05.2020)
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Journal Article
Loss of GTF2I promotes neuronal apoptosis and synaptic reduction in human cellular models of neurodevelopment
Adams, Jason W., Vinokur, Annabelle, de Souza, Janaína S., Austria, Charles, Guerra, Bruno S., Herai, Roberto H., Wahlin, Karl J., Muotri, Alysson R.
Published in Cell reports (Cambridge) (26.03.2024)
Published in Cell reports (Cambridge) (26.03.2024)
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Journal Article
SARS-CoV-2 infects human brain organoids causing cell death and loss of synapses that can be rescued by treatment with Sofosbuvir
Mesci, Pinar, de Souza, Janaina S, Martin-Sancho, Laura, Macia, Angela, Saleh, Aurian, Yin, Xin, Snethlage, Cedric, Adams, Jason W, Avansini, Simoni H, Herai, Roberto H, Almenar-Queralt, Angels, Pu, Yuan, Szeto, Ryan A, Goldberg, Gabriela, Bruck, Patrick T, Papes, Fabio, Chanda, Sumit K, Muotri, Alysson R
Published in PLoS biology (03.11.2022)
Published in PLoS biology (03.11.2022)
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Journal Article
Down Syndrome iPSC-Derived Astrocytes Impair Neuronal Synaptogenesis and the mTOR Pathway In Vitro
Araujo, Bruno H. S., Kaid, Carolini, De Souza, Janaina S., Gomes da Silva, Sérgio, Goulart, Ernesto, Caires, Luiz C. J., Musso, Camila M., Torres, Laila B., Ferrasa, Adriano, Herai, Roberto, Zatz, Mayana, Okamoto, Oswaldo K., Cavalheiro, Esper A.
Published in Molecular neurobiology (01.07.2018)
Published in Molecular neurobiology (01.07.2018)
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Journal Article
IGF1 neuronal response in the absence of MECP2 is dependent on TRalpha 3
de Souza, Janaina S, Carromeu, Cassiano, Torres, Laila B, Araujo, Bruno H S, Cugola, Fernanda R, Maciel, Rui M B, Muotri, Alysson R, Giannocco, Gisele
Published in Human molecular genetics (15.01.2017)
Published in Human molecular genetics (15.01.2017)
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Journal Article
Selenium supplementation during pregnancy and lactation promotes metabolic changes in Wistar rats' offspring
Laureano‐Melo, Roberto, Império, Güínever E., Kluck, George E. G., da Conceição, Rodrigo R., de Souza, Janaina S., Marinho, Bruno G., Giannocco, Gisele, Côrtes, Wellington S.
Published in Clinical and experimental pharmacology & physiology (01.07.2020)
Published in Clinical and experimental pharmacology & physiology (01.07.2020)
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Journal Article
Unravelling the intravenous and in situ vasopressin effects on the urinary bladder in anesthetized female rats: More than one vasopressin receptor subtype involved?
Cafarchio, Eduardo M., Auresco, Luciana C., da Silva, Luiz A., Rodart, Itatiana F., do Vale, Barbara, de Souza, Janaina S., Antonio, Bruno B., Venancio, Daniel P., Giannocco, Gisele, Aronsson, Patrik, Sato, Monica A.
Published in European journal of pharmacology (05.09.2018)
Published in European journal of pharmacology (05.09.2018)
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Journal Article
Regularly swimming exercise modifies opioidergic neuromodulation in rostral ventrolateral medulla in hypertensive rats
Almeida, Roberto L., Ogihara, Cristiana A., de Souza, Janaína S., Oliveira, Kelen C., Cafarchio, Eduardo M., Tescaro, Larissa, Maciel, Rui M.B., Giannocco, Gisele, Sato, Monica A.
Published in Brain research (01.01.2022)
Published in Brain research (01.01.2022)
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Journal Article
Triiodothyronine Treatment reverses Depression-Like Behavior in a triple-transgenic animal model of Alzheimer’s Disease
Maglione, Andréa V., do Nascimento, Bruna P. P., Ribeiro, Miriam O., de Souza, Talytha J. L., da Silva, Renata E. C., Sato, Monica A., Penatti, Carlos A. A., Britto, Luiz R. G., de Souza, Janaina S., Maciel, Rui M.B., da Conceição, Rodrigo Rodrigues, Laureano-Melo, Roberto, Giannocco, Gisele
Published in Metabolic brain disease (01.12.2022)
Published in Metabolic brain disease (01.12.2022)
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Journal Article
Novel lincRNA Susceptibility Gene and Its Role in Etiopathogenesis of Thyrotoxic Periodic Paralysis
Melo, Maria Clara C, de Souza, Janaína S, Kizys, Marina M L, Vidi, Angela C, Dorta, Haron S, Kunii, Ilda S, Giannocco, Gisele, Carvalheira, Gianna, Dias-da-Silva, Magnus R
Published in Journal of the Endocrine Society (01.07.2017)
Published in Journal of the Endocrine Society (01.07.2017)
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Journal Article
Down Syndrome iPSC-Derived Astrocytes Impair Neuronal Synaptogenesis and the mTOR Pathway In Vitro
Araujo, Bruno H. S., Kaid, Carolini, De Souza, Janaina S., Gomes da Silva, Sérgio, Goulart, Ernesto, Caires, Luiz C. J., Musso, Camila M., Torres, Laila B., Ferrasa, Adriano, Herai, Roberto, Zatz, Mayana, Okamoto, Oswaldo K., Cavalheiro, Esper A.
Published in Molecular neurobiology (01.07.2018)
Published in Molecular neurobiology (01.07.2018)
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Journal Article
SARS-CoV-2 infects human brain organoids causing cell death and loss of synapses that can be rescued by treatment with Sofosbuvir
Pinar Mesci, Janaina S. de Souza, Laura Martin-Sancho, Angela Macia, Aurian Saleh, Xin Yin, Cedric Snethlage, Jason W. Adams, Simoni H. Avansini, Roberto H. Herai, Angels Almenar-Queralt, Yuan Pu, Ryan A. Szeto, Gabriela Goldberg, Patrick T. Bruck, Fabio Papes, Sumit K. Chanda, Alysson R. Muotri
Published in PLoS biology (01.11.2022)
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Published in PLoS biology (01.11.2022)
Journal Article