Chronic brain inflammation and persistent herpes simplex virus 1 thymidine kinase expression in survivors of syngeneic glioma treated by adenovirus-mediated gene therapy: Implications for clinical trials
Castro, M.G, Löwenstein, P.R, Dewey, R. A, Morrissey, G, Cowsill, C. M, Stone, D, Bolognani, F, Dodd, N.J.F, Southgate, T. D, Klatzmann, D, Lassmann, H
Published in Nature medicine (01.11.1999)
Published in Nature medicine (01.11.1999)
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Neuronal and glial cell type-specific promoters within adenovirus recombinants restrict the expression of the apoptosis-inducing molecule Fas ligand to predetermined brain cell types, and abolish peripheral liver toxicity
Morelli, AE, Larregina, AT, Smith-Arica, J, Dewey, RA, Southgate, TD, Ambar, B, Fontana, A, Castro, MG, Lowenstein, PR
Published in Journal of general virology (01.03.1999)
Published in Journal of general virology (01.03.1999)
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Radioprotective gene therapy through retroviral expression of manganese superoxide dismutase
Southgate, Thomas D., Sheard, Victoria, Milsom, Michael D., Ward, Timothy H., Mairs, Robert J., Boyd, Marie, Fairbairn, Leslie J.
Published in The journal of gene medicine (01.05.2006)
Published in The journal of gene medicine (01.05.2006)
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Adenovirus-mediated herpes simplex virus type-1 thymidine kinase gene therapy suppresses oestrogen-induced pituitary prolactinomas
WINDEATT, S, SOUTHGATE, T. D, LÖWENSTEIN, P. R, CASTRO, M. G, DEWEY, R. A, BOLOGNANI, F, PERONE, M. J, LARREGINA, A. T, MALENIAK, T. C, MORRIS, I. D, GOYA, R. G, KLATZMANN, D
Published in The journal of clinical endocrinology and metabolism (01.03.2000)
Published in The journal of clinical endocrinology and metabolism (01.03.2000)
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Long-term transgene expression within the anterior pituitary gland in situ: impact on circulating hormone levels, cellular and antibody-mediated immune responses
Southgate, T D, Stone, D, Williams, J C, Lowenstein, P R, Castro, M G
Published in Endocrinology (Philadelphia) (01.01.2001)
Published in Endocrinology (Philadelphia) (01.01.2001)
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Central nervous system toxicity of two adenoviral vectors encoding variants of the herpes simplex virus type 1 thymidine kinase : reduced cytotoxicity of a truncated HSV1-TK
COWSILL, C, SOUTHGATE, T. D, CASTRO, M. G, MORRISSEY, G, DEWEY, R. A, MORELLI, A. E, MALENIAK, T. C, FORREST, Z, KLATZMANN, D, WILKINSON, G. W. G, LÖWENSTEIN, P. R
Published in Gene therapy (01.04.2000)
Published in Gene therapy (01.04.2000)
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Adenoviruses encoding HPRT correct biochemical abnormalities of HPRT-deficient cells and allow their survival in negative selection medium
SOUTHGATE, T. D, BAIN, D, FAIRBANKS, L. D, MORELLI, A. E, LARREGINA, A. T, SIMMONDS, H. A, CASTRO, M. G, LÖWENSTEIN, P. R
Published in Metabolic brain disease (01.12.1999)
Published in Metabolic brain disease (01.12.1999)
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Gene transfer into enteric neurons of the rat small intestine in organ culture using a replication defective recombinant herpes simplex virus type 1 (HSV1) vector, but not recombinant adenovirus vectors
BROWN, O. A, SANTER, R. M, SHERING, A. F, LARREGINA, A. T, MORELLI, A. E, SOUTHGATE, T. D, CASTRO, M. G, LOWENSTEIN, P. R
Published in Gene therapy (01.04.1997)
Published in Gene therapy (01.04.1997)
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